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Topic: Cytokine



  
 Antioxidants attenuate the plasma cytokine response to exercise in humans -- Vassilakopoulos et al. 94 (3): 1025 -- ...
with leukocyte infiltration; the cytokine response that eccentric
the observed attenuation of the cytokine response to exercise
Cytokine response to eccentric exercise in young and elderly humans.
http://jap.physiology.org/cgi/content/full/94/3/1025   (5093 words)

  
 Cytokines
Some of these cytokines are being used to treat patients that have deficiencies in hematopoiesis, such as cancer patients whose bone marrow are damaged by anti-cancer drug therapy.
The functional activity of these cytokines are critical for adaptive immune responses and redundancy might confer an evolutionary advantage to the host.
However, using this approach will at least give you a working knowledge of cytokine biology and help keep them straight.
http://www.hsc.wvu.edu/micro/test/cytos/cytokine.html   (1978 words)

  
 Modulation of Cytokine Profiles by the Mycoplasma Superantigen Mycoplasma arthritidis Mitogen Parallels Susceptibility ...
Early serum cytokine levels in response to MAM in vivo.
the cytokine profile toward a type 2 response (28).
Trinchieri, G. Interleukin 12: a proinflammatory cytokine with immunoregulatory functions that bridge innate resistance and antigen-specific adaptive immunity.
http://iai.asm.org/cgi/content/full/68/3/1142   (5683 words)

  
 Ureaplasma urealyticum Modulates Endotoxin-Induced Cytokine Release by Human Monocytes Derived from Preterm and Term ...
Induction of human neonatal pulmonary fibroblast cytokines by hyperoxia and Ureaplasma urealyticum.
Results are from a representative experiment of three experiments.
University of Maryland School of Medicine, UMAB Cytokine Core Laboratory,
http://iai.asm.org/cgi/content/full/69/6/3906   (3669 words)

  
 Th1 Cytokine Patterns in Cervical Human Papillomavirus Infection -- Scott et al. 6 (5): 751 -- Clinical and Vaccine ...
The interpretation of the varied cytokine responses seen in HPV-negative individuals (Table 3) is unclear but again highlights
To further investigate cytokine patterns associated with cervical HPV infection, we examined cross-sectional cytokine data
We hypothesized that a Th1 cytokine response, defined as a pattern
http://cdli.asm.org/cgi/content/full/6/5/751   (3666 words)

  
 Institute of Clinical Immunology Cytokine data collection
This two day conference will provide a unique forum for all specialties and disciplines with interests in the clinical and scientific aspects of Cytokine Medicine.
I have to warn you, though - this is material I´m constantly working with, it´s UNFINISHED and in continuous change!
If you want to go DEEPER into signaling pathways, have a look at
http://www.personal.uni-jena.de/~iuj/start.html   (454 words)

  
 Cytokine Gene Expression Occurs More Rapidly in Stimulated Peripheral Blood Mononuclear Cells from Human ...
Recently, we examined the kinetics of cytokine mRNA expression in PBMC from normal healthy subjects in response to various
Studies of changes in cytokines in HIV+ persons
at all other time points for that particular cytokine were expressed
http://cdli.asm.org/cgi/content/full/7/5/769   (3218 words)

  
 01_main
The CCL is a full-service research core laboratory focused on the measurement of cytokines and growth factors using immunoassays.
Our goal is to serve our clients with high quality data at a low cost.
Data is for research purposes only and is not intended for diagnostic use.
http://www.cytokines.com   (146 words)

  
 Cytokine - Wikipedia, the free encyclopedia
Cytokines mediate many important physiological functions including growth, development, wound healing and immune response.
Some studies have shown links between cytokine levels and clinical depression [1].
For instance, there are several known cytokines that have both stimulating and suppressing action on lymphocyte cells and immune response.
http://en.wikipedia.org/wiki/Cytokine   (488 words)

  
 Differential Role for Competitive Reverse Transcriptase-Polymerase Chain Reaction and Intracellular Cytokine Staining ...
Intracellular cytokine analysis by flow cytometry is a powerful
In contrast to the intracellular cytokine staining, the amount
For the experiments in which RNA was isolated from graft-infiltrating
http://ajp.amjpathol.org/cgi/content/full/157/5/1453   (2871 words)

  
 Cytokine function of heat shock proteins -- Tsan and Gao 286 (4): C739 -- AJP - Cell Physiology
Hsp70 stimulates cytokine production through a CD-14-dependent pathway, demonstrating its dual role as a chaperone and cytokine.
the reported cytokine function of HSPs, with particular emphasis
Furthermore, the observed HSP cytokine effects are mediated
http://ajpcell.physiology.org/cgi/content/full/286/4/C739   (4707 words)

  
 IngentaConnect Anti-cytokine autoantibodies: Epiphenomenon or critical modulator...
High-titered autoantibodies induced by cytokine therapy are of clinical concern since their occurrence is often associated with the loss of response to treatment.
Their levels, although highly variable, are increased in the circulation of patients subjected to cytokine therapy or suffering from a variety of immunoinflammatory diseases.
Keywords: interferon-alpha; -beta and -gamma; autoantibodies to cytokines; autoimmunity; cytokine therapy; interleukins
http://www.ingentaconnect.com/content/klu/biot/1997/00000010/00000001/00129236   (384 words)

  
 A Point Mutation of Tyr-759 in Interleukin 6 Family Cytokine Receptor Subunit gp130 Causes Autoimmune Arthritis -- ...
Laboratory for Cytokine Signaling, RIKEN Research Center for Allergy and Immunology (RCAI), Yokohama, Kanagawa 230-0045, Japan
of cytokine mRNA expression were analyzed by Mann-Whitney U
Quantitative RT-PCR analysis of cytokine transcripts in the
http://www.jem.org/cgi/content/full/196/7/979   (6468 words)

  
 Encyclopedia: Cytokine
The term stimulus (plural: stimuli) has several related meanings: In physiology, a stimulus is something external that elicits or influences a physiological or psychological activity or response.
Cytokines also regulate a process known as programmed cell death, or apoptosis, which is in part responsible for alcohol-induced destruction of liver tissue.
Alcohol Research and Health: Cytokines—central factors in alcoholic liver disease
http://www.nationmaster.com/encyclopedia/Cytokine   (349 words)

  
 Human Endothelial Cells Effectively Costimulate Cytokine Production by, But Not Differentiation of, Naive CD4+ T Cells ...
the single-cell level by use of an intracellular cytokine staining technique
producers may imply that the intracellular cytokine staining technique
For characterization and enumeration of cytokine producers in the
http://www.jimmunol.org/cgi/content/full/161/5/2158   (6801 words)

  
 One Lambda - Product
"Genetic regulation of cytokine synthesis: Consequences for acute and chronic organ allograft rejection." (1998) Graft 1, 15-21
Researchers are currently investigating the role of cytokine expression levels in diseases such as cancer, AIDS, and autoimmune diseases.
Research suggests that polymorphic variants of cytokine genes may be associated with acute and chronic transplant rejection.
http://www.onelambda.com/product/product.asp?productid=42&productlineID=4   (171 words)

  
 Cytokine Bioassays
Bacterial endotoxins are effective inducers of cytokines; hence, their presence in the bioassay cultures should be eliminated.
The following tables summarize the conditions and reagents needed for human and mouse cytokine bioassays.
Biological activity of cytokines and their concentrations are commonly measured by cellular proliferation of primary cell cultures or isolated cell lines that are dependent and/or responsive to a specific growth factor.
http://www.ebioscience.com/ebioscience/appls/BAC.htm   (759 words)

  
 SOCS Proteins: Negative Regulators of Cytokine Signaling -- Krebs and Hilton 19 (5): 378 -- Stem Cells
SOCS2, and SOCS3 are upregulated in response to cytokine stimulation,
cytokine and the pattern of SOCS mRNAs it induces.
Cytokine stimulation activates the JAK-STAT pathway, leading to the induction of CIS, SOCS1, SOCS2, and/or SOCS3.
http://stemcells.alphamedpress.org/cgi/content/full/19/5/378   (5407 words)

  
 Diabetes: Aberrant Macrophage Cytokine Production Is a Co... @ HighBeam Research
Moreover, the finding of elevated IL-12 production by NOD M[Phi] in response to several stimuli suggests that this aspect of cytokine dysregulation could enhance autoreactive Th1 responses in diverse settings.
These observations suggest that some Idd susceptibility loci may be associated with the regulation of cytokine expression, especially that by M[Phi].
The latter process may interfere with the early establishment of important regulatory pathways and thus disrupt the normal pathway of disease (53).
http://www.highbeam.com/library/doc0.asp?DOCID=1G1:63713277&refid=holomed_1   (7529 words)

  
 Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies.
We show the specificity of this technique by blocking cytokine staining using a molar excess of recombinant cytokine.
The state of the art may have changed since the publication date.
Recently, there have been several reports demonstrating improvements in the flow cytometric detection of intracellular cytokines.
http://www.aegis.com/aidsline/1996/apr/M9640183.html   (592 words)

  
 The Transforming Growth Factor-{beta} Superfamily Cytokine Macrophage Inhibitory Cytokine-1 Is Present in High ...
Cytokines in the TGF-ß superfamily are thought to have
Serum Macrophage Inhibitory Cytokine 1 as a Marker of Pancreatic and Other Periampullary Cancers
of this cytokine, we have also assessed the capacity of a placental
http://jcem.endojournals.org/cgi/content/full/85/12/4781   (4786 words)

  
 Cytokine WebFacts
NOTE: You will only be able to view cytokine profiles if you are logged in.
Institute of Child Health, University College London, UK Choose a cytokine
For problems or suggestions concerning this service, please contact: webmaster@elsevier-international.com
http://www.cytokinewebfacts.com   (176 words)

  
 Inhibitors of Cytokine Signal Transduction -- Wormald and Hilton 279 (2): 821 -- Journal of Biological Chemistry
in response to cytokine will certainly prove a challenge for
Negative regulation of signal transduction pathways is necessary
for an appropriate cellular and physiological response to cytokine
http://www.jbc.org/cgi/content/full/279/2/821   (3352 words)

  
 Mechanisms of Soluble Cytokine Receptor Generation -- Levine 173 (9): 5343 -- The Journal of Immunology
Pulmonary-Critical Care Medicine Branch, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD 20892
Cytokines affecting endothelial and smooth muscle cells in vascular disease
cytokine receptors that mediate antagonistic and agonistic effects.
http://www.jimmunol.org/cgi/content/full/173/9/5343   (4850 words)

  
 Intracellular Cytokine Staining
Table 2: Human Cytokine Intracellular Staining Quick Guide
A modification of the basic immunofluorescence staining and flow cytometric analysis protocol can be used for the simultaneous analysis of surface molecules and intracellular cytokines at single-cell level.
In contrast to detection of secreted cytokines by ELISA, for detection of intracellular cytokines, it is necessary to block secretion of cytokines with reagents such as Monensin or Brefeldin A during the last few hours of the stimulation.
http://www.ebioscience.com/ebioscience/appls/FCI.htm   (833 words)

  
 Cytokine and Cytokine Receptor Pleiotropy and Redundancy -- Ozaki and Leonard 277 (33): 29355 -- Journal of Biological ...
This should clarify the specific structural basis for the ability
Cytokines represent a diverse group of molecules that collectively exert a wide range of actions (1).
typical cytokines, have similar structures and signaling mechanisms
http://www.jbc.org/cgi/content/full/277/33/29355   (3821 words)

  
 Cytokine, Inflammatory Response & Other Immunology-Related Arrays gene array
Interferon a,b Response cDNA GEArray in HybTube Format
The Immunology GEArray DNA Microarrays and RT² Profiler PCR Arrays are designed to monitor the expression profiles of genes that encode many important immunological molecules including interleukins, chemokines, receptors, and lymphocytic activation markers.
Cytokine, Inflammatory Response & Other Immunology-Related Arrays gene array
http://www.superarray.com/cytoki.php   (391 words)

  
 OUP: Cytokine Network: Balkwill
Cytokine and cytokine antagonists have shown therapeutic potential in a number of chronic and acute diseases.
The Cytokine Network: Frontiers in Molecular Biology is not a survey of individual cytokines, but guides the reader through the latest research on the cytokine network as a whole covering genomics, signalling pathways, control of the immune response, and therapeutics.
Viral homologues exist for many cytokines and receptors and genetic variations in cytokine production may influence response to pathogenic stimuli.
http://www.oup.co.uk/isbn/0-19-963702-4   (443 words)

  
 BD Biosciences : Pharmingen : Protocols : Cytokine ELISA Protocol
In these cases, it may be necessary to use complementary techniques such as multi-probe ribonuclease protection assay analysis, immunofluorescent intracellular cytokine staining with flow cytometric analysis, or ELISPOT, to gauge the relative levels of cytokine expression by various test cell populations.
It should be noted that in addition to providing a rich source of information for clinical and basic science research studies, sandwich ELISA for measuring cytokines and their receptors have become increasingly important as diagnostic tools and for monitoring therapeutic regimens,
For example, because test samples often come from tissue culture supernatants or biological fluids which are conditioned with cytokines produced by mixed cell populations, the ELISA data does not provide direct information on the identities and frequencies of individual cytokine producing cells.
http://www.bdbiosciences.com/pharmingen/protocols/Cytokine_ELISA.shtml   (1934 words)

  
 HON Allergy Glossary Cytokine
Cytokines are soluble glycoproteins released by cells of the immune system, which act nonenzymatically through specific receptors to regulate immune responses.
Cytokines resemble hormones in that they act at low concentrations bound with high affinity to a specific receptor.
http://www.hon.ch/Library/Theme/Allergy/Glossary/cytokine.html   (39 words)

  
 International Cytokine Society
Cytokines, Cellular and Molecular Therapy - on-line journal
This is a trial to collect data on cytokines, carried out by the Institute of Clinical Immunology, FSU Jena, Germany.
Cytokine and Growth Factor Reviews (CGR) - at Elsevier Science
http://www.weizmann.ac.il/cytokine   (322 words)

  
 Growth Factors and Cytokines
, IL-6 does not induce cytokine expression; its main effects, therefore, are to augment the responses of immune cells to other cytokines.
A large family of cytokines are produced by various cells of the body.
CSFs are cytokines that stimulate the proliferation of specific pluripotent stem cells of the bone marrow in adults.
http://web.indstate.edu/thcme/mwking/growth-factors.html   (2547 words)

  
 Cytokines Web
Potential roles of recently dicovered Human cytokines in diagnosis and treatment of disease
Clinical Significance - potential uses of Human cytokines in diagnosis and treatment of disease
The Cytokines Web provides leading-edge scientific information about cytokines and their receptors, including 3-D structural information and topological and evolutionary relationships.
http://cmbi.bjmu.edu.cn/cmbidata/cgf/CGF_Database/cytweb   (414 words)

  
 Cytokine Polymorphism Component
The final protocol for this has not been completed, but we anticipate that each participating laboratory will carry out phase II studies on at least 100 samples collected from selected racial/ethnic groups, transplant patients, or patients being studied in the disease components.
This interest is due to the fact that certain of these polymorphisms have been shown to correlate with cytokine plasma levels in vitro or with the survival of kidney, heart or lung allografts.
We therefore felt that it would be appropriate and desirable to establish a cytokine polymorphism component (CPC) within the framework of the 13th IHWG.
http://www.ihwg.org/components/cytokine/cytover.htm   (599 words)

  
 C2479 Cytokine Network
It is not a survey of individual cytokines, but a guide to the cytokine network covering genomics, signaling pathways, control of the immune response, and therapeutics.
Cytokines act in a complex network where one cytokine can influence production of, and response to other cytokines.
This book covers the study of cytokine and cytokine receptor structure, elucidation of convergent intracellular signaling pathways, molecular genetics, and targeted gene disruption to 'knock-out' production of individual cytokines in mice.
http://www.sigmaaldrich.com/catalog/search/ProductDetail?ProdNo=C2479&Brand=SIGMA   (131 words)

  
 Academic Press: Cytokine Reference: Individual License
Continued use of Cytokine Reference indicates your acceptance of these terms.
I Agree to the Terms of the License
License: You are granted a license to access and use Cytokine Reference for your personal research purposes for a period of 24 hours after guest registration.
http://www.apnet.com/companions/0122526708/demolicense.htm   (502 words)

  
 Immunology and cytokine ELISPOT assays
While ELISPOT assay techniques have existed for two decades now, modern ELISPOT analysis is typically performed using ELISPOT readers, which employ computer vision techniques to enumerate the cytokine-producing cells.
One such tool is the cytokine ELISPOT assay, which provides a means to count cytokine-producing cells within a suspension.
They also have more sophisticated techniques for measuring the functions and secretions of these cells.
http://www.angelfire.com/mech/elispot/cytokine-elispot.html   (256 words)

  
 Scientist
Vasocative Intestinal Peptide (VIP): Neurotransmitter, Hormone and Cytokine.
The murine erythrocyte protein-4.2- encoding gene: similarity and differences in structure and expression from its human counterpart.
http://bahrikaracay.com/scientist/scientist.htm   (958 words)

  
 CIG - Internet Sites of Interest to Cytokine researchers
CIG - Internet Sites of Interest to Cytokine researchers
http://www.nih.gov/sigs/cytokine/cig_links.html   (19 words)

  
 RayBiotech, Inc. - Welcome to RayBiotech.com
Furthermore, the experiment can be performed at a general laboratory setting without any specialized equipment and special training.
By using our system, you can rapidly and accurately identify the expression profiles of more than
RayBio® Cytokine Antibody Arrays use a proprietary, patent-pending technology for high-throughput analysis of cytokine expression.
http://www.raybiotech.com/product.htm   (333 words)

  
 Cytokines and Cytokine Products - PeproTech for the Americas
PeproTech is devoted to providing life science research with the highest quality cytokine products.
These products are all available through secure online ordering from all product and search result pages.
Cytokines and Cytokine Products - PeproTech for the Americas
http://www.peprotech.com   (65 words)

  
 Cytokine Family Database
The Cytokine Family Database (dbCFC) is a collection of EST (Expressed Sequence Tag) records of cytokines deposited in the NCBI GenBank.
Sakaki (University of Tokyo, Institute of Medical Science, Human Genome Center)
EST sequences in the dbCFC were periodically BLAST-searched by us, and the identification of each EST record in the dbCFC is not necessarily identical to the identifier that is found, for example, in the DEFINITION line of the GenBank record.
http://cytokine.medic.kumamoto-u.ac.jp   (216 words)

  
 Cytokine Homepage
has replaced the contents of my previous Cytokine homepage
http://www.lmb.uni-muenchen.de/groups/ibelgaufts/cytokines.html   (9 words)

  
 cytokine webs
CD28 costimulation and cytokine production in aging mice
CTLA-4 (CD152) inhibits cytokine production by downmodulating NF-kB
http://www.geocities.com/CapeCanaveral/Lab/8180/cytokine.htm   (25 words)

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