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Topic: Cyclophosphamide



  
 Johns Hopkins Vasculitis Center Discusses Cytoxan Treatment for Vasculitis
Cyclophosphamide is one of a number of medications first developed as a chemotherapy drug (a medication used in the treatment of cancer).
In a long-term study of the effectiveness of cyclophosphamide in treating lupus, the risk of infertility among women of childbearing potential was 57%.
Normally, even after the rash and other symptoms of chickenpox subside, the virus that caused the sickness continues to reside in the body in a “dormant” state, hiding in the root of one of the nerves along the spine.
http://vasculitis.med.jhu.edu/treatments/cytoxan.html   (1880 words)

  
 Safety and efficacy of intravenous pulse cyclophosphamide in acute steroid refractory inflammatory bowel disease -- ...
intravenous cyclophosphamide pulse therapy was used in refractory
Intravenous pulse cyclophosphamide therapy in Crohn's disease and ulcerative colitis
pulse cyclophosphamide therapy and decreased from 479 to 157
http://gut.bmjjournals.com/cgi/content/full/52/3/377   (2755 words)

  
 MedlinePlus Drug Information: Cyclophosphamide (Systemic)
Cyclophosphamide may also be used for other conditions as determined by your doctor.
Before you begin treatment with cyclophosphamide, you and your doctor should talk about the good this medicine will do as well as the risks of using it.
While you are being treated with cyclophosphamide, and after you stop treatment with it, do not have any immunizations (vaccinations) without your doctor's approval.
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202174.html   (2359 words)

  
 MedlinePlus Drug Information: Cyclophosphamide
Talk to your doctor about the possible risks of using this drug for your condition.
tell your doctor and pharmacist if you are allergic to cyclophosphamide or any other drugs.
This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a682080.html   (570 words)

  
 Arthritis Research Campaign Drugs for Arthritis: Cyclophosphamide
Some drugs interact with cyclophosphamide, so you should discuss any new medications with your doctor before starting them, and you should always tell any other doctor treating you that you are taking cyclophosphamide.
If you would like any further information about cyclophosphamide, or if you have any concerns about your treatment, you should discuss this with your doctor, rheumatology nurse or pharmacist.
Some doctors prescribe a drug called mesna along with cyclophosphamide to try and reduce the risk of cystitis.
http://www.arc.org.uk/about_arth/infosheets/6244/6244.htm   (1060 words)

  
 Cyclophosphamide - Family factsheets - GOSH and ICH
If cyclophosphamide is used to treat conditions other than cancer, leukaemia and bone marrow transplants, it may be given by mouth in tablet form.
This fact sheet explains what cyclophosphamide is, how it is given and some of the possible side effects.
This test will also be used to monitor the heart during the course of treatment and at long-term follow-up clinic.
http://www.gosh.nhs.uk/factsheets/families/F000243   (1018 words)

  
 Cyclophosphamide news articles
Both cytotoxic drugs (methotrexate, cladribine, azathioprine, chlorambucil, cyclophosphamide and ciclosporin) and immunomodulators (chloroquine...
By itself, however, the so-called metronomic therapy with Cytoxan (cyclophosphamide) and methotrexate was ineffective, reported Harold Burstein, MD, Ph.D., of...
http://www.mongabay.com/drugs/drugs/Cyclophosphamide.html   (6429 words)

  
 CYCLOPHOSPHAMIDE
Cyclophosphamide and two of its metabolites, 4-hydroxycyclophosphamide and phosphoramide mustard were analyzed for their ability to induce sister chromatid exchanges in mouse peripheral blood lymphocytes in vitro and in vivo.
The latter cmpd may be responsible for the hemorrhagic cystitis seen during therapy with cyclophosphamide.
Mesna, a drug that acts to detoxify metabolites of cyclophosphamide, has been used in human medicine to preclude hemorrhagic cystitis.
http://www.frankmckinnon.com/cyclophosphamide.htm   (17325 words)

  
 Cyclophosphamide – Cytoxan, Neosar - Chemotherapy Drugs - Chemo
You will be checked regularly by your doctor while you are taking cyclophosphamide, to monitor side effects and check your response to therapy.
Cyclophosphamide – Cytoxan, Neosar - Chemotherapy Drugs - Chemo
Meaning, your ability to conceive or father a child may be affected by cyclophosphamide.
http://www.chemocare.com/BIO/cyclophosphamide.asp   (1484 words)

  
 Imaginis - Profiles of Breast Cancer Drugs
cyclophosphamide, doxorubicin (Adriamycin), and fluorouracil (this therapy is called CAF)
cyclophosphamide (Cytoxan), methotrexate (Amethopterin, Mexate, Folex), and fluorouracil (Fluorouracil, 5-Fu, Adrucil) (this therapy is called CMF)
doxorubicin (Adriamycin) and cyclophosphamide (this therapy is called AC)
http://imaginis.com/breasthealth/bc_drugs.asp   (2628 words)

  
 Patient Education - Cyclophosphamide
Cyclophosphamide is not used to treat arthritis itself except in very unusual circumstances.
There may be an increased risk of some other forms of cancer while taking this medication.
To avoid pregnancy, it is important that an effective form of birth control be used while taking this medication.
http://www.rheumatology.org/public/factsheets/cyclophosphamide.asp?aud=pat   (921 words)

  
 cyclophosphamide (oral/injection) - [Medication]
Your doctor will determine the correct amount and frequency of treatment with cyclophosphamide depending upon the type of cancer being treated and other factors.
Your doctor will probably want you to have regularly scheduled blood tests and other medical evaluations during treatment with cyclophosphamide to monitor progress and side effects.
Your pharmacist has additional information about cyclophosphamide written for health professionals that you may read.
http://www.peacehealth.org/kbase/multum/d00036a1.htm   (1389 words)

  
 A mouse-based strategy for cyclophosphamide pharmacogenomic discovery -- Watters et al. 95 (4): 1352 -- Journal of ...
cyclophosphamide response, we have determined in vitro and in
are consistent with the notion that cyclophosphamide induces
G-CSF is an essential regulator of neutrophil trafficking from the bone marrow to the blood.
http://jap.physiology.org/cgi/content/full/95/4/1352   (4332 words)

  
 Cyclophosphamide-Induced Cystitis and Bladder Cancer in Patients with Wegener Granulomatosis -- Talar-Williams et al. ...
As a function of time receiving cyclophosphamide therapy.
All patients received cyclophosphamide as part of clinical research
in monitoring cyclophosphamide treated patients for the development
http://www.annals.org/cgi/content/full/124/5/477   (4308 words)

  
 Cyclophosphamide (Cytoxan®, Neosar®) - PetPlace.com
One common example is its use in a multiple-drug treatment plan for lymphoma in dogs.
Consult with your veterinarian to determine if other drugs your pet is receiving could interact with cyclophosphamide.
Cyclophosphamide is one of a number of drugs that is effective in treating some cancers and tumors.
http://www.petplace.com/articles/artShow.asp?artID=1546   (646 words)

  
 Cyclophosphamide - [Medication]
Cyclophosphamide is effective against many forms of cancer.
Cyclophosphamide is effective against many forms of cancer, including:
Cyclophosphamide can also be used to suppress the immune system in diseases such as:
http://www.peacehealth.org/kbase/topic/detail/drug/tv6593/detail.htm   (328 words)

  
 Cyclophosphamide
Patients should be encouraged to drink plenty of fluids (3-4 L/day) during therapy, void frequently, and avoid taking the drug at night.
Personnel should be wearing surgical gloves and a closed front surgical gown with knit cuffs.
Genitourinary: Severe, potentially fatal acute hemorrhagic cystitis or urinary fibrosis, believed to be a result of chemical irritation of the bladder by acrolein, a cyclophosphamide metabolite, occurs in 7% to 12% of patients and has been reported in up to 40% of patients in some series.
http://www.musc.edu/pharmacyservices/Drugs/C/Cyclophosphamide.htm   (828 words)

  
 Lupus: A Patient Care Guide for Nurses and Other Health Professionals Patient Information Patient Information Sheet ...
You will need to work closely with your doctor and nurse to make sure that the amount of the drug you are taking gives you the benefits you need with as few side effects as possible.
If you want to have a baby in the future, talk to your doctor about the option of storing your eggs or sperm before beginning therapy.
Cyclophosphamide is a drug used to treat a number of cancers, and it is used to treat patients with lupus when major organs, such as the kidneys, are affected.
http://www.niams.nih.gov/hi/topics/lupus/lupusguide/chppis16.htm   (417 words)

  
 Cyclophosphamide Cancer Therapy May Offer Lupus Patients New Hope
Cyclophosphamide Cancer Therapy May Offer Lupus Patients New Hope
Title: Cyclophosphamide Cancer Therapy May Offer Lupus Patients New Hope
Investigators believe "reprogramming" the immune system could be an effective way of treating such disorders.
http://www.docguide.com/dg.nsf/PrintPrint/E9A427B8355D5DA485256CAA0052EAEB   (765 words)

  
 Lymphoma Information Network - Cyclophosphamide / Cytoxan
Please consult with a doctor or the literature provided with the drug packaging if you need specific information on a drug.
This drug has been known to affect fertility.
Cyclophosphamide (brand names Cytoxan, Neosar in the US, cytoxan or procytox in Canada) is a chemotherapy agent used in the treatment of Non-Hodgkin's lymphoma (NHL) and other forms of cancer.
http://www.lymphomainfo.net/therapy/drugs/cytoxan.html   (425 words)

  
 Cyclophosphamide + PE Rx
During a course of therapy this regimen is given 6 times, one every 4 weeks.
The patient is treated with cyclophosphamide (Cytoxan), a total of 1.0 gm/M
The patient should be sent home with enough antiemetics for 2-3 days.
http://www.neuro.wustl.edu/neuromuscular/antibody/ctxrx.html   (322 words)

  
 Cyclophosphamide
Immune mediated diseases (especially those of life-threatening nature such as Immune Mediated Hemolytic Anemia)
Cyclophosphamide is a serious drug used to treat very serious disease.
In the treatment of immune mediated disease, it is common and usual to use cyclophosphamide in conjunction with corticosteroids (such as
http://www.marvistavet.com/html/body_cyclophosphamide_.html   (564 words)

  
 cyclophosphamide (Cytoxan) - drug class, medical uses, medication side effects, and drug interactions by MedicineNet.com
MedicineNet Home > Medications A-Z List > Cancer Home Page > cyclophosphamide
PRESCRIBED FOR: Cyclophosphamide is used for the treatment of several types of cancers and often in combination with other drugs to treat breast cancer, leukemia and ovarian cancer.
DRUG CLASS AND MECHANISM: Cyclophosphamide is a drug that is used primarily for treating several types of cancer.
http://www.medicinenet.com/cyclophosphamide/article.htm   (670 words)

  
 Sequential Dose-Dense Doxorubicin, Paclitaxel, and Cyclophosphamide for Resectable High-Risk Breast Cancer: Feasibility ...
Coombes RC, Bliss JM, Wils J, et al: Adjuvant cyclophosphamide, methotrexate, and fluorouracil versus fluorouracil, epirubicin, and cyclophosphamide in premenopausal women with axillary node-positive operable breast cancer: Results of a randomized trial.
cyclophosphamide was decreased by one third in these two patients.
and cyclophosphamide at escalated doses is feasible and associated
http://www.jco.org/cgi/content/full/17/1/93   (4442 words)

  
 MedlinePlus Medical Encyclopedia: Arthritis
It is very important to take your medications as directed by your doctor.
Immunosuppressants -- these drugs, like azathioprine or cyclophosphamide, are used for serious cases of rheumatoid arthritis when other medications have failed.
Such medications, including etanercept (Enbrel), infliximab (Remicade) and adalimumab (Humira), are administered by injection and can dramatically improve your quality of life.
http://www.nlm.nih.gov/medlineplus/ency/article/001243.htm   (1802 words)

  
 The Treatment of Feline Fibrosarcoma with Lipopolysaccharide and Cyclophosphamide;
The Treatment of Feline Fibrosarcoma with Lipopolysaccharide and Cyclophosphamide
The Treatment of Feline Fibrosarcoma with Lipopolysaccharide and Cyclophosphamide;
To overcome this, we used a combination therapy of LPSp and the alkylating agent cyclophosphamide which induces TNF
http://www.priory.com/vet/feline.htm   (1823 words)

  
 Encyclopedia: Cyclophosphamide
Cyclophosphamide is a nitrogen mustard alkylating agent, used to treat various types of cancer and some autoimmune disorders.
Chemotherapy is the use of chemical substances to treat disease.
In addition, its use is becoming more common in (Any of a large group of diseases characterized by abnormal functioning of the immune system that causes your immune system to produce antibodies against your own tissues) autoimmune diseases where (additional info and facts about disease-modifying antirheumatic drug) disease-modifying antirheumatic drugs (DMARDs) have been ineffective.
http://www.nationmaster.com/encyclopedia/Cyclophosphamide   (633 words)

  
 Peculiar pattern of nail pigmentation following cyclophosphamide therapy
A 47-year-old woman, diagnosed with pemphigus vulgaris was started on dexamethasone-cyclophosphamide pulse therapy.
As dexamethasone has not been reported to cause pigmentation, this change in our patient was attributed to cyclophosphamide.
This therapy included monthly pulses of a single intravenous dose of 500 mg cyclophosphamide with 3 days of intravenous infusion of 100 mg of dexamethasone and daily doses of 50 mg cyclophosphamide orally in the intervening days between pulses.
http://dermatology.cdlib.org/93/case_reports/nails/thappa.html   (667 words)

  
 ADAP drugs: cyclophosphamide
Cyclophosphamide is a cancer treatment, and is used to treat Hodgkinís disease, lymphomas, leukemias, and a variety of other tumors.
It should be used cautiously if there are active infections, bone marrow depression, or chronic debilitating illnesses.
Treatment with cyclophosphamide may decrease antibody response to live virus vaccines and increase the risk of adverse reactions.
http://www.atdn.org/access/drugs/cyclop.html   (379 words)

  
 Cyclophosphamide for multiple sclerosis (Cochrane Review)
Cyclophosphamide (CFX) is a cytotoxic and immunosuppressive agent, used in systemic autoimmune diseases.
This review shows that the overall effect of CFX (administered as intensive schedule) in the treatment of progressive MS does not support its use in clinical practice.
Background: Multiple sclerosis is a presumed cell-mediated autoimmune disease of the central nervous system.
http://www.cochrane.org/cochrane/revabstr/ab002819.htm   (447 words)

  
 Cytoxan Online, Description, Chemistry, Ingredients - Cyclophosphamide - RxList Monographs
Cyclophosphamide is a synthetic antineoplastic drug chemically related to the nitrogen mustards.
Cyclophosphamide is soluble in water, saline, or ethanol and has the following structural formula:
Cyclophosphamide is a white crystalline powder with the molecular formula C
http://www.rxlist.com/cgi/generic3/cyclophosphamide.htm   (150 words)

  
 Phase I Study of 131I-Anti-CD45 Antibody Plus Cyclophosphamide and Total Body Irradiation for Advanced Acute Leukemia ...
From the Division of Clinical Research, Fred Hutchinson Cancer Research Center, and the Departments of Pediatrics, Medicine and Radiology, University of Washington, Seattle, WA; and Pacific Northwest National Laboratories, Richland, WA.
Phase I Study of 131I-Anti-CD45 Antibody Plus Cyclophosphamide and Total Body Irradiation for Advanced Acute Leukemia and Myelodysplastic Syndrome -- Matthews et al.
I-Anti-CD45 Antibody Plus Cyclophosphamide and Total Body Irradiation for Advanced Acute Leukemia and Myelodysplastic Syndrome
http://www.bloodjournal.org/cgi/content/full/94/4/1237   (7496 words)

  
 Cyclophosphamide - definition of Cyclophosphamide in Encyclopedia
Embed a dictionary search in your own web page
http://encyclopedia.laborlawtalk.com/Cyclophosphamide   (41 words)

  
 Product Label
FDA Oncology Tools Approval Summary for cyclophosphamide for
Study Details (Click on NDA or Supplement Number to view details)
http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=21   (19 words)

  
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