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| | Gastroenterology Chapter 6 Pathophysiology of Peptic Ulcer Disease |
 | | Another therapeutic approach to the patient with peptic ulcer disease, based on different pathophysiologic mechanisms, includes the use of drugs that enhance mucosal defense. | | | Hereditary factors are important in the pathogenesis of peptic ulcer disease, as suggested by a higher prevalence of peptic ulcer disease in certain genetic syndromes. | | | There is epidemiologic evidence suggesting that the incidence and behavior of chronic peptic ulcers vary according to the site at which they occur. |
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http://gastroresource.com/gitextbook/en/chapter6/6-4-pr.htm
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| | Harvey Williams Cushing (www.whonamedit.com) |
| | Cushings first experience of pituitary disease was in 1901, when he carried out a decompression of a girl aged 14 who had complained of headaches and visual failure. | | | Cushing contributed to the study of blood pressure during surgery and developed the method of local anaesthesia during surgery. | | | In Switzerland in 1900-1901 Cushing studied the blood-pressure-spinal-pressure problem and demonstrated in a classic experiment that as the spinal fluid pressure of a dog is increased, there is initially a vagal effect with bradycardia followed by a high rise in arterial blood pressure. |
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http://www.whonamedit.com/doctor.cfm/980.html
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| | eMedicine - Glucocorticoid Therapy and Cushing Syndrome : Article by George P Chrousos, MD, FAAP, FACP, MACE |
| | Transsphenoidal surgical excision remains the treatment of choice for Cushing disease, with a cure rate of 50-95% for the first exploration, depending upon the experience of the surgeon, the size and position of the tumor, and the duration of follow-up care. | | | Cushing disease: With transsphenoidal pituitary surgery, the cure rate for uncomplicated cases is approximately 95% and the recurrence rate is about 5%. | | | Background: Cushing syndrome (CS) takes its name from Harvey Cushing, who, in 1912, was one of the first physicians to report a patient affected with excessive glucocorticoid. |
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http://www.emedicine.com/ped/topic1068.htm
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| | eMedicine - Cushing Syndrome : Article by Gail Adler |
| | The primary therapy for Cushing disease is transsphenoidal surgery, and the primary therapy for adrenal tumors is adrenalectomy. | | | Treatment of choice for classic Cushing disease is transsphenoidal surgery by an experienced neurosurgeon. | | | Patients with an ACTH-producing pituitary tumor (Cushing disease) may develop headaches, polyuria and nocturia, visual problems, or galactorrhea. |
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http://www.emedicine.com/med/topic485.htm
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| | Cushing' Syndrome Laboratorial Diagnosis - Endocrinology - MEDSTUDENTS |
| | Because so many of the problems found in Cushings Syndrome are also seen in the absence of the disorder, we look particulary for features of Cushings syndrome not often seen in the general population (e.g., severe hypertension in young person, severe metabolic bone disease, violaceous striae). | | | Also, it must be stressed out that the term "Cushings Disease" is a specific type of Cushings Syndrome whose ethiology is Pituitary Adenoma ACTH producer (generally it is due to microadenoma). | | | First of all, the process should start with a detailed anamnesis and physical exam of the suspect patient as there are various situations that may bring confusion to the analysis: classified as Pseudo Cushings Syndrome or Cushing ACTH independent (facticia type) Syndrome, for instance. |
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http://www.medstudents.com.br/endoc/endoc7.htm
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| | Harvey Williams Cushing (www.whonamedit.com) |
| | Cushings first experience of pituitary disease was in 1901, when he carried out a decompression of a girl aged 14 who had complained of headaches and visual failure. | | | In Switzerland in 1900-1901 Cushing studied the blood-pressure-spinal-pressure problem and demonstrated in a classic experiment that as the spinal fluid pressure of a dog is increased, there is initially a vagal effect with bradycardia followed by a high rise in arterial blood pressure. | | | Although he improved and developed several surgical procedures, there is no particular "Cushing surgical procedure", but it is obvious that he, more than any other, proved the feasibility of intracranial surgery. |
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http://www.whonamedit.com/doctor.cfm/980.html
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| | Pet Owner's Crash Course in Canine Cushing's Disease |
| | Cushing's Disease (hyperadrenocorticism) is a common condition in older dogs, often mistaken for the aging process itself. | | | Although most dogs with Cushing's disease cannot be cured, their quality of life (as well as the owner's quality of life) can be improved, and their lives may be extended with early intervention. | | | Iatrogenic Hyperadrenocorticism: The third cause of Cushing's is one that we can create ourselves if we give a dog too much external glucocorticoid, especially for chronic conditions like allergies. |
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http://www.kateconnick.com/library/cushingsdisease.html
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| | eMedicine - Peptic Ulcer Disease : Article by Meta Carroll, MD |
| | The ulcer associated with a brain tumor or injury (Cushing ulcer) is characterized as single, deep, and prone to perforation; associated with high gastric acid output; and located in the duodenum or stomach. | | | Background: The lesion of peptic ulcer disease (PUD) is a disruption in the mucosal layer of the stomach or duodenum. | | | Surgical Care: Surgical intervention is required in a small percentage of infants and children with complications of PUD that include perforation, obstruction, intractable pain, and bleeding unresponsive to medical or endoscopic therapy. |
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http://www.emedicine.com/ped/topic2341.htm
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| | Miniature Horse Cushing's Syndrome - Cushings |
| | "Currently, we do recognize that some breeds (Morgans especially) and types of equids (ponies in particular) are at greater risk of developing Cushing's disease. | | | "Even though the clinical symptoms are often very obvious, a number of tests have been developed over the years to positively diagnose Cushings Disease in horses. | | | These observations, accompanied by the fact that Cushing's disease has been recognized for a number of decades in horses, suggest that genetics likely plays a more important role than environment in development of Cushing's disease." |
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http://www.mini-horse.org/health_care_cushings.html
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| | ICU - Stress Ulceration |
| | Although this structure is not completely understood, it serves as a valuable concept in understanding the pathogenesis of peptic ulcer disease. | | | This includes "Cushing's Ulcer", which is seen classically in patients suffering from prolonged coma from any cause. | | | The cure was often no better, with a mortality of approximately 70% associated with surgery for this condition. |
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http://www.anzics.com.au/teaching/phvc/stressul.html
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| | Which patients require stress ulcer prophylaxis in ICU? |
| | In 1842 Curling described a series of cases of severe duodenal ulceration associated with burns; in 1832 Cushing reported ulcer disease associated with surgery and trauma. | | | Fulminant peptic ulcer disease in cardiac surgical patients: pathogenesis, prevention, and management. | | | Prophylactic therapy for stress ulcer bleeding: a reappraisal. |
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http://www.4um.com/tutorial/CCM/ulcer.htm
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| | Canine Cushings Disease - Jacks Tale |
| | However, its clinical affects are hard to monitor, because responses to the main test for Cushing's Disease are unaffected. | | | It was first described in humans by Dr Harvey Cushing in 1932, and is called a 'syndrome' in the 15% of cases which are linked to the adrenal gland, and a 'disease' in the 85% of cases that are linked to the pituitary gland. | | | Cushing's is rather like an insidious cloak that gradually envelopes the sufferer, and where previously there stood a floodlight, a light bulb gradually takes its place. |
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http://www.firstscience.com/site/editor/005_ramblings_04042003.asp
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| | Dr. Harvey Williams Cushing / Cushing's Help and Support |
| | Cushing’s first experience of pituitary disease was in 1901, when he carried out a decompression of a girl aged 14 who had complained of headaches and visual failure. | | | Cushing contributed to the study of blood pressure during surgery and developed the method of local anaesthesia during surgery. | | | In Switzerland in 1900-1901 Cushing studied the blood-pressure-spinal-pressure problem and demonstrated in a classic experiment that as the spinal fluid pressure of a dog is increased, there is initially a vagal effect with bradycardia followed by a high rise in arterial blood pressure. |
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http://www.cushings-help.com/harvey.htm
(4965 words)
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| | the GASTROLAB Gastrointestinal Encyclopedia |
| | Rabeprazole A drug used in the treatment of reflux oesophagitis and ulcer disease. | | | Remicade Trademark for a drug containing infliximab, used in the treatment of Crohn´s disease. | | | Rokitansky-Cushing ulcer Ulcerative lesions in the lower third of the oesophagus, gastric fundus or duodenum associated with and probably due to severe brain lesions. |
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http://www.gastrolab.net/dicter.htm
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| | FAQ Cushing's Syndrome |
| | In the cat, the clinical feature’s of Cushing’s disease are similar to those in the dog: excess water consumption, muscle wasting, pot-bellied appearance, thin coat, and skin abnormalities. | | | There are several mechanisms which can lead to Cushing’s syndrome and, as they are treated differently, it is important to determine which one is at work in a given animal. | | | This symptom, present in over 90% of Cushing’s syndrome dogs, results from hormonal redistribution of body fat plus a breakdown of abdominal musculature. |
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http://www.iol.ie/~pjmathew/faqcush.htm
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| | Cushings syndrome 1 |
| | Cushing's syndrome should be talked about briefly in school just to inform students about this disease. | | | After thorough research, there is no information on Cushing's Syndrome being taught in schools. | | | If a pituitary tumor can not be removed, radiation therapy to the pituitary tumor can be used, but the improvement in the Cushing's syndrome is much slower (NADF,2004). |
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http://www.ulm.edu/kinesiology/Spr2004cushings.html
(1291 words)
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| | Cushing's Syndrome/Disease Links |
| | Navigate to Health Clinic, 2) disease, 3) Endocrine Disease, 4) Cushing's. | | | Auburn University College of Veterinary Medicine- Cushing's Disease FAQs | | | The National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health- Cushing's Syndrome |
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http://www.io.com/~lolawson/cushings/cushlinks.html
(618 words)
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| | Cushing, Harvey -- Britannica Student Encyclopedia |
| | Discusses the diagnosis and treatment of the disease, as well as research being conducted through the National Institutes of Health. | | | The illness known as Cushing's disease or syndrome was named for the man who first described it, Harvey Williams Cushing. | | | History of 20th-century neurological surgery, with an emphasis on the career of Harvey Cushing. |
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http://www.britannica.com/ebi/article?tocId=9273883
(618 words)
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| | CUSHINGS SYNDROME |
| | Cushings Syndrome is a very serious disease that requires professional care. | | | My experience with Cushings I can honestly say is limited, but those cases I have examined with EAV have shown abnormally high energy values in the Adrenal Glands, Pituitary, Liver, Small Intestine, and Colon and lower than normal values in the Pancreas, bone marrow and immune system. | | | The syndrome can be due to iatrogenics or doctor induced, from administration of therapeutics amounts of corticosteroids (prednisone, prednisilone, depomedrol, etc.) over a protracted period of time. |
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http://www.holisticvetpetcare.com/cushings-syndrome.htm
(819 words)
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| | Client Education Series: Cushings Syndrome |
| | Cushings animals have thromboembolic disease due to glomerulopathy and antithrombin III loss, vascular stasis (blood pooling) due to an increase in blood cell numbers, damage to blood vessels due to hypertension, and an increase in clotting factors in the bloodstream. | | | Pituitary dependent Cushings disease is caused by a functional pituitary tumor that stimulates the adrenal glands to produce excess cortisol. | | | Cushings syndrome is a condition in which there is an excess of cortisol (cortisone). |
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http://www.vetmed.auburn.edu/dcs/sac/mededu/cushings/home.html
(2572 words)
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| | Q&A - Ask Dr Mike |
| | Hypothyroidism is the most common hormonal disease in dogs and hyperadrenocorticism (Cushing's disease) is probably second. | | | In older dogs these conditions can be associated with hormonal imbalances, such as hypothyroidism or hyperadrenocorticism (Cushing's disease). | | | Hormonal diseases can cause bizarre symptoms in some patients and hypothyroidism, hyperadrenocorticism and hypoadrenocorticism could cause the the symptoms seen. |
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http://www.vetinfo.com/Q&A.html
(2572 words)
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| | Pituitary Network Association - Disorders - Cushing’s Syndrome |
| | For patients whose Cushing's disease is not controlled with surgery, both conventional (external beam) and stereotactic radiosurgery are effective in controlling cortisol levels and tumor growth in many patients. | | | These patients with "pseudo-Cushing's" may be difficult to distinguish from those with true Cushing's disease. | | | The only way to achieve long term cure of Cushing's disease is by transsphenoidal removal of theadenoma. |
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http://www.pituitary.org/disorders/cushings_disease.aspx
(801 words)
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| | Cushing's Syndrome |
| | Several therapies are available to treat the ACTH-secreting pituitary adenomas of Cushing's disease. | | | Understanding the basis of Cushing's syndrome will yield new approaches to therapy. | | | Cushing's syndrome is a hormonal disorder caused by prolonged exposure of the body's tissues to high levels of the hormone cortisol. |
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http://endocrine.niddk.nih.gov/pubs/cushings/cushings.htm
(2803 words)
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| | Table of Contents / Cushing's Help and Support |
| | Cushing's Disease in Dogs — A Case Study | | | Harvey Cushing, the Doctor who discovered this awful disease | | | Harvey Williams Cushing, for whom this disease is named |
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http://www.cushings-help.com/toc.htm
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