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Topic: Creatinine



  
 A Brief Review of Creatinine Concentration
A clay that specifically absorbs creatinine prior to reacting with alkaline picrate is available, but is difficult to manipulate and is often messy.
In addition, elevations in creatinine concentration do not correlate with a proportionate loss of renal function, further complicated by the body’s diversion pathways (discussed in the following paragraphs) to metabolize an overabundance of creatinine.
Balint and Visy proved that noncreatinine chromagens were absent from the urine of the dog in 1965, which implies that there are alternate elimination pathways for these compounds.
http://www.vet.uga.edu/vpp/clerk/miller   (3057 words)

  
 Hypertension Online Slides - creatinine clearance, blood pressure, creatinine
Also, the mean increase in the serum creatinine and the mean decrease in creatinine clearance were significantly slower in the irbesartan group.
The patients in the amlodipine group had worse renal outcomes than those in the irbesartan group, although there was equal control of blood pressure in the amlodipine group.
The regular measurement of certain clinical and laboratory parameters provides a useful guide to the success of therapy in patients with chronic renal disease.
http://www.hypertensiononline.org/slides2/slide01.cfm?q=creatinine+clearance   (1477 words)

  
 Renally excreted drug dosing review
Use of a very low serum creatinine (0.5 mg% or less) in the C&G equation leads to a falsely elevated CL Therefore, many practitioners designate 0.7 mg% as the minimum SCr which should be used in the equation.
Furthermore, much controversy exists as to which method is best for a particular patient group.
The following conditions may falsely elevate serum creatinine, thereby falsely decreasing the creatinine clearance.
http://www.rxkinetics.com/renal.html   (1924 words)

  
 K/DOQI Update 2000
Serum creatinine and the creatinine index are predictors of clinical outcome.
Direct relationships between serum creatinine and the serum albumin
The relationship between the creatinine index and the edema-free lean body mass or skeletal muscle protein mass needs to be defined for ESRD patients.
http://www.kidney.org/professionals/kdoqi/guidelines_updates/nut_a05.html   (672 words)

  
 Creatinine
Creatinine is a breakdown product of creatine, which is an important
Lab values may change suddenly (within a few days to 2 weeks):
creatinine, depends on muscle mass, which fluctuates very little.
http://www.geocities.com/worldwidebarnes/Creatinine.htm   (1473 words)

  
 Adult Health Advisor 2005.4: Blood (Serum) Creatinine Test
You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition.
Ask your health care provider when and how you will get the result of your test.
This information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment.
http://www.med.umich.edu/1libr/aha/aha_creatini_crs.htm   (583 words)

  
 Creatinine - Wikipedia, the free encyclopedia
Creatinine is a breakdown product of creatine phosphate in muscle, and is usually produced at a fairly constant rate by the body (depending on muscle mass).
Men tend to have higher levels of creatinine because they have more skeletal muscle than women.
Measuring serum creatinine is a simple test and it is the most commonly used indicator of renal function.
http://en.wikipedia.org/wiki/Creatinine   (378 words)

  
 Creatinine Blood Levels — Complete medical explanation regarding the production of this chemical waste molecule on ...
Elderly persons, on the other hand, may have less creatinine in their blood than the norm.
Creatinine is produced from creatine, a molecule of major importance for energy production in muscles.
Abnormally high levels of creatinine thus warn of possible malfunction or failure of the kidneys, sometimes even before a patient reports any symptoms.
http://www.medicinenet.com/creatinine_blood_test/article.htm   (527 words)

  
 Creatinine clearance Medical Information
Creatinine is used for this purpose, since it is normally present in the body and very little creatinine is reabsorbed after it is filtered.
Veins and arteries vary in size from one patient to another and from one side of the body to the other.
Drugs that can interfere with creatinine clearance measurements include: cimetidine, trimethoprim, and nephrotoxic drugs, such as cephalosporins (cefoxitin).
http://www.drugs.com/enc/creatinine_clearance.html   (1116 words)

  
 Cystatin C versus Creatinine in Renovascular Disease -- Olivieri et al. 48 (12): 2256 -- Clinical Chemistry
this is indeed what currently happens in the so-called creatinine
Creatinine was assayed by the Jaffe method on a DAX 96 multichannel
not recognized by creatinine measurements in some ischemic patients
http://www.clinchem.org/cgi/content/full/48/12/2256   (1550 words)

  
 Creatinine: The Test
For more information on reference ranges, please read Reference Ranges and What They Mean.
The creatinine blood test may be ordered, along with the BUN test, at regular intervals when the patient has a known kidney disorder or has a disease that may affect kidney function or be exacerbated by dysfunction.
Increased creatinine levels in the blood suggest diseases or conditions that affect kidney function.
http://www.labtestsonline.org/understanding/analytes/creatinine/test.html   (573 words)

  
 Creatinine Test Principal Health News
Normal values can vary from laboratory to laboratory, but are generally in the following ranges:
Similarly, other patients may have creatinine levels in which muscle abnormalities must be taken into consideration, such as long-term corticosteroid therapy, high thyroid (hyperthyroidism), muscular dystrophy, or paralysis.
Some drugs that may increase creatinine values include gentamicin, cimetidine, heavy-metal chemotherapeutic agents (e.g., cisplatin), and other drugs toxic to the kidneys, such as the cephalosporins.
http://www.principalhealthnews.com/topic/topic100586675   (562 words)

  
 Creatinine and Creatinine Clearance
Also, people who have large muscles, such as athletes, normally have above-average blood creatinine levels.
A high creatinine level may mean your kidneys are not working properly.
A BUN-to-creatinine ratio can help your health professional predict which conditions, such as dehydration, may be causing abnormal BUN and creatinine levels and decreased kidney function.
http://www.webmd.com/hw/lab_tests/hw4322.asp   (1830 words)

  
 Diavant - Analytes - Renal Parameters - Creatinine
Home > Analytes > Renal Analytes > Creatinine
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Creatinine is the most important marker for renal function, because it is steadily produced in the muscles and excreted via the kidneys in the urine.
http://www.diavant.us/diavant/CMSFront.html?pgid=1,5,15,0   (256 words)

  
 Serum creatinine is a poor marker of GFR in nephrotic syndrome -- Branten et al. 20 (4): 707 -- Nephrology Dialysis ...
Department of Medicine, Division of Nephrology, University Medical Center, Nijmegen, The Netherlands
that the tubular handling of creatinine is altered in patients
By regression analysis serum albumin was identified as an independent
http://ndt.oxfordjournals.org/cgi/content/abstract/20/4/707   (261 words)

  
 Creatinine Clearance
Many medications must be adjusted for renal impairment when the CrCl falls below 50 mL/min.
In pediatrics, it is generally corrected to a body surface area of 1.73 m2 (standard body surface area of an adult).
Reference range in our laboratory of an "uncorrected" creatinine clearance for an adult male is 90-139 mL/minute, and for an adult female is 80-125 mL/minute.
http://www-users.med.cornell.edu/~spon/picu/calc/crclcalc.htm   (121 words)

  
 Creatine and Creatinine Metabolism -- Wyss and Kaddurah-Daouk 80 (3): 1107 -- Physiological Reviews
Creatine and Creatinine Metabolism -- Wyss and Kaddurah-Daouk 80 (3): 1107 -- Physiological Reviews
suggest that Cr and creatinine may be precursors of food mutagens
It must be stressed that the detailed contribution of different bodily tissues (pancreas, kidney, liver, testis) to total Cr synthesis is still rather unclear and may vary between species (see text).
http://physrev.physiology.org/cgi/content/full/80/3/1107   (9456 words)

  
 Serum creatinine
A panic value for creatinine is 10 mg/dl in nondialysis patients.
A patient's BUN and creatinine should always be checked before giving nephrotoxic drugs.
Measuring serum creatinine is a useful and inexpensive method of evaluating renal dysfunction.
http://www.rnceus.com/renal/renalcreat.html   (476 words)

  
 Section 2 - Creatinine clearance
The relationship between creatinine clearance and overall drug elimination can be used to predict an optimum dose for a patient.
Jelliffe's multi-step method, which corrects for rising serum creatinine, may be more accurate in these patients.
Most authorities state that these equations should not be used in patients with liver disease.
http://www.rxkinetics.com/pktutorial/2_1.html   (687 words)

  
 Creatinine clearance - Wikipedia, the free encyclopedia
Creatinine is used because it fulfills these requirements (though not perfectly) and it is produced naturally by the body (creatinine is a metabolite of creatine, which is found in muscle).
For example grading of chronic renal insufficiency and dosage of drugs that are primarily excreted via urine are based on GFR (creatinine clearance).
In general, creatinine clearance is the removal of creatinine from the body.
http://en.wikipedia.org/wiki/Creatinine_clearance   (434 words)

  
 Creatinine Clearance
The nurse has an important role in instructing the patient about the purpose of the test and the procedures that will be used.
The creatinine clearance test is used to diagnose renal dysfunction and is also used to evaluate the progression of renal disease.
Because all the creatinine filtered by the kidneys in a given time interval is excreted into the urine, creatinine levels are equivalent to the glomerular filtration rate (GFR); the rate at which the kidneys process blood through the glomerular system.
http://www.rnceus.com/renal/renalcc.html   (304 words)

  
 Creatinine: Common Questions
Once in the muscle, some of the creatine is spontaneously converted to creatinine.
Creatine is a compound that is made primarily in the liver and then transported to your muscles, where it is used as an energy source for muscle activity.
An increased ratio may be due to a condition that causes a decrease in the flow of blood to the kidneys, such as congestive heart failure or dehydration.
http://www.labtestsonline.org/understanding/analytes/creatinine/faq.html   (376 words)

  
 Creatinine
Creatinine is a protein produced by muscle and released into the blood.
Creatinine: What is it and why is it important?
Infants that have little muscle will have lower normal levels (0.2).
http://www.transweb.org/qa/qa_txp/faq_creat.html   (467 words)

  
 Creatinine Level --The Doctors Lounge(TM)
A drug might interfere with the measurement of creatinine and cause it to be falsely high (known as Jaffee Reaction)
In a crush injury muscle may be crushed and release creatinine, its difficult to tell what the kidney function is.
If you are a body builder and you have too much muscle, your creatinine might be high but your kidney function normal.
http://www.thedoctorslounge.net/forums/backup/topic-175.html   (322 words)

  
 Ref. HB008 Creatinine
Most of the creatinine is found in muscle tissue where it is present as creatine phosphate and serve as a high energy storage reservoir for conversion to ATP.
This method is linear up to 15 mg/dl.
Creatinine in a basic picrate solution forms a coloured complex.
http://www.diagnostics.be/products/clinical/biochemistry/hb008.htm   (215 words)

  
 creatinine - definition of creatinine in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and ...
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
creatinine - definition of creatinine in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia.
A creatine anhydride formed by the metabolism of creatine and found in muscle tissue and blood and normally excreted in the urine as metabolic waste.
http://medical-dictionary.thefreedictionary.com/creatinine   (96 words)

  
 Thermo Electron Corporation --Infinity™ Creatinine
The reagent is suitable for manual use or on automated clinical chemistry analyzers.
Applications for a wide range of automated analyzers are available on request.
The Infinity™ Creatinine single liquid stable reagent offers the laboratory all the convenience of single liquid stability to help maximize laboratory productivity, minimize operator error and provide quick result turnaround time.
http://www.thermo.com/com/cda/product/detail/0,1055,23203,00.html   (114 words)

  
 MDAdvice.com - Health Library - Medical Tests
If you are an athlete with exceptionally well-developed muscles, you may have above-average creatinine levels, even with normal kidney function.
Acromegaly* and gigantism* may be accompanied by elevated creatinine.
From Complete Guide to Medical Tests by H. Winter Griffith, M.D. Copyright by Fisher Books.
http://www.mdadvice.com/library/test/medtest59.html   (576 words)

  
 Estimated Creatinine Clearance
Note: this formula is applicable only if the serum creatinine is stable.
Please enter the weight, sex, age and serum Cr.
http://www.intmed.mcw.edu/clincalc/creatinine.html   (34 words)

  
 Creatinine Clearance Calculator
Creatinine Clearance = (140 - Age)(kg) / (72 x Creatinine)
http://www.medstudents.com.br/calculat/creatcle.htm   (20 words)

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