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| | Cooperative - Encyclopedia.WorldSearch |
 | | In biochemistry, a macromolecule that exhibits cooperative behavior has ligand binding characteristics that depend on the amount of ligand bound. | | | Because We Can Change the World: A Practical Guide To Building Cooperative, Inclusive Classroom Communities | | | Worldwide, the cooperative movement often has links and associations with Green politics or Socialist politics, with socially responsible investing and the social enterprise movement. |
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http://encyclopedia.worldsearch.com/cooperative.htm
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| | Cooperative DNA-binding by Bicoid provides a mechanism for threshold-dependent gene activation in the Drosophila embryo |
| | For example, cooperative binding by Bicoid to its sites in the hb upstream regulatory element is thought to result in a sharp posterior boundary of hb expression that specifies the position of the cephalic furrow. | | | Cooperative binding by Bicoid monomers appears to be pairwise (Figure 3B). | | | Cooperative DNA binding also results in concerted loading of Bicoid sites, and thus steepens the transition between the on and off states for gene activation, sharpening the borders of the expression domains as observed for both hunchback and eve stripe 2. |
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http://www.nature.com/cgi-taf/DynaPage.taf?file=/emboj/journal/v17/n20/full/7591292a.html
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| | Study Guide Week 4 |
| | Is the cooperative binding of O2 by Hb electrostatic or mechanical? | | | Describe/compare the three types of binding, cooperative, non-cooperative, un-cooperative. | | | n>1, then cooperative binding, n<1, then un-cooperative binding, n=1, then non-cooperative binding. |
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http://www-biology.ucsd.edu/classes/bibc100.SP98/StudyGuideWeek4.html
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| | Bhoite, Leena T - Residues important for cooperative binding of the Swi5p zinc finger and Pho2p homeodomain proteins at the HO promoter |
| | Deletion analysis of the proteins also revealed that DNA-binding domains of either were sufficient for binding to the HO promoter but additional regions were required for cooperative binding (JBC 270:29151). | | | Residues important for cooperative binding of the Swi5p zinc finger and Pho2p homeodomain proteins at the HO promoter | | | Further, changing the spacing between the binding sites does not block cooperative interactions, suggesting flexibility in at least one protein's interaction domain. |
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http://www.yeastgenome.org/yeast96/f2219.html
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| | Preferential Interactions of the Escherichia coli LexA Repressor with Anions and Protons Are Coupled to Binding the RecA Operator |
| | Binding of LexA repressor to the recA operator in the presence of NaCl ranging from 25 to 400 mM at picomolar DNA concentration showed a broad, apparently noncooperative, binding isotherm. | | | Binding of LexA repressor in NaF at the same [DNA] yielded binding isotherms with a narrow transition, reflecting an apparently cooperative binding process. | | | The binding of Escherichia coli LexA repressor to the recA operator was examined as a function of the concentration of NaCl, KCl, NaF, and MgCl |
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http://pubs.acs.org/cgi-bin/abstract.cgi/bichaw/1997/36/i05/abs/bi9618427.html
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| | ssDNA-dependent colocalization of adeno-associated virus Rep and herpes simplex virus ICP8 in nuclear replication domains -- Heilbronn et al. 31 (21): 6206 -- Nucleic Acids Research |
| | Dudas,K.C. and Ruyechan,W.T. (1998) Identification of a region of the herpes simplex virus single-stranded DNA-binding protein involved in cooperative binding. | | | Mapelli,M., Mühleisen,M., Persico,G., van der Zandt,H. and Tucker,P.A. (2000) The 60-residue C-terminal region of the single-stranded DNA binding protein of herpes simplex virus type 1 is required for cooperative DNA binding. | | | Lee,S.S. and Lehman,I.R. (1997) Unwinding of the box I element of a herpes simplex virus type 1 origin by a complex of the viral origin binding protein, single-strand DNA binding protein and single-stranded DNA. |
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http://nar.oupjournals.org/cgi/content/full/31/21/6206
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| | Protein Dimers and Cooperative Binding |
| | Cooperative binding refers to mechanisms in which the first of several protein binding reactions occurs at a relatively low rate, while subsequent binding reactions occur more rapidly, because the presence of the already bound protein enhances the binding affinity. | | | A similar power law behavior is obtained in cooperative binding of proteins to a substrate. | | | The active form of many enzymes, including the DNA binding proteins we propose using, is a bound combination of two copies of the protein. |
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http://www-swiss.ai.mit.edu/projects/amorphous/papers/cellgates/node5.html
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| | cooperative binding |
| | An excellent example of cooperative binding was discovered by Gehrhardt and Pardee in their study of the enzyme Aspartate transcarbamylase. | | | The term cooperative binding derives from the property that the binding of one molecule of substrate makes it easier for the second molecule of substrate to bind. | | | A model to explain the sigmoid shape of the curve is called the cooperative binding model. |
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http://academic.brooklyn.cuny.edu/biology/bio4fv/page/coopera.htm
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| | Cooperative binding of c-Myb and Pax-5 activates the RAG-2 promoter in immature B cells -- Kishi et al. 99 (2): 576 -- Blood |
| | Cooperative binding of c-Myb and Pax-5 activates the RAG-2 promoter in immature B cells -- Kishi et al. | | | (A) Binding of c-Myb and Pax-5 to the | | | 17 oligonucleotide, the oligonucleotide containing the consensus c-Myb binding sequence (c-Myb) or its mutant binding sequence (c-Mybm), the oligonucleotide containing the consensus Pax-5 binding sequence (Pax-5) or its mutant binding sequence (Pax-5m), or the oligonucleotide containing the consensus GATA binding sequence (GATA). |
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http://www.bloodjournal.org/cgi/content/full/99/2/576
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| | Structure/Function Relationships of Hemoglobin |
| | As shown later, when the saturation behavior of hemoglobin (i.e., its oxygen binding capacity) is regulated according to the first equation above, each hemoglobin molecule is capable of transporting about twice as many oxygen molecules under normal physiological conditions than would be possible if the saturation behavior obeyed the second equation. | | | Hemoglobin’s primary function is to bind oxygen that diffuses into the bloodstream from the lungs and then transport it to outlying tissues where it is released primarily for aerobic respiration. | | | Without hemoglobin’s specialized cooperative ligand binding behavior, nearly twice as much hemoglobin would be needed to transport the same amount of oxygen and this requirement would presumably require twice the blood volume to accommodate a doubling of the number of red blood cells for housing the additional hemoglobin. |
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http://tutor.lscf.ucsb.edu/instdev/sears/biochemistry/tw-hbn/hba-overview.htm
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| | Mathews/van Holde/Ahern 3rd Edition |
| | The Hill plot for noncooperative binding will, according to equation (7.9), be a straight line with slope = 1. | | | - Hill plots readily identify the transition between binding states in cooperativity, and the binding behavior is unmistakably different for cooperative and noncooperative systems. | | | The Hill coefficient must be greater than unity in order for the Hill plot to switch over from the weak-binding line to the strong-binding line. |
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http://oregonstate.edu/instruction/bb451/winter2004/common451/ch07/c07hp.htm
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| | Mathews/van Holde/Ahern 3rd Edition |
| | - Hill plots readily identify the transition between binding states in cooperativity, and the binding behavior is unmistakably different for cooperative and noncooperative systems. | | | The Hill plot for noncooperative binding will, according to equation (7.9), be a straight line with slope = 1. | | | As binding progresses, the curve switches over to approach another, parallel line that describes the strong-binding state (small P |
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http://oregonstate.edu/instruction/bb451/winter2004/common451/ch07/c07hp.htm
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| | Hill coefficient - Wikipedia, the free encyclopedia |
| | The Hill coefficient was originally devised to explain the cooperative binding of oxygen to Hemoglobin (a system which has a Hill coefficient of 2.8-3). | | | In biochemistry, the binding of a ligand to a macromolecule is often enhanced if there are already other ligands present on the same macromolecule (this is known as Cooperative binding). | | | A coefficient of 1 indicates completely independent binding, regardless of how many additional ligands are already bound. |
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http://en.wikipedia.org/wiki/Hill_coefficient
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| | Hill Coefficient Encyclopedia Article, Definition, History, Biography |
| | The Hill coefficient was originally devised to explain the cooperative binding of oxygen to Hemoglobin (a system which has a Hill coefficient of 2.8-3). | | | In biochemistry, the binding of a ligand to a macromolecule is often enhanced if there are already other ligands present on the same macromolecule (this is known as Cooperative binding). | | | A coefficient of 1 indicates completely independent binding, regardless of how many additional ligands are already bound. |
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http://www.karr.net/search/encyclopedia/Hill_coefficient
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| | Table of contents for Biochemistry laboratory |
| | Ligand-Macromolecule Interactions (Molecular Recognition) Properties of Noncovalent Binding Interactions Quantitative Characterization of Ligand Binding Scatchard's Equation Cooperative Binding of Ligands Experimental Measurement of Ligand-Binding Interactions The Bradford Protein Assay as an Example of Ligand Binding Computer Software for Analysis of LM Binding B. | | | Radioisotopes in Biochemistry Origin and Properties of Radioactivity Detection and Measurement of Radioactivity Radioisotopes and Safety Study Problems Further Reading Chapter 4 Centrifugation Techniques in Biochemistry A. | | | Affinity Chromatography and Immunoadsorption Chromatographic Media The Immobilized Ligand Attachment of Ligand to Matrix Experimental Procedure for Affinity Chromatography Immunoadsorption Study Problems Further Reading Chapter 6 Characterization of Proteins and Nucleic Acids by Electrophoresis A. |
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http://www.loc.gov/catdir/toc/ecip058/2005005103.html
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| | 2002 Publications |
| | Schumacher, M. Miller, S. Grkovic, M. Brown, R. Skurray and R. Brennan, "Structural Basis for Cooperative DNA Binding by Two Dimers of the Multidrug-binding Protein QacR", EMBO J. Schumacher, R. Pearson, T. Moller, P. Valentin-Hansen and R. Brennan,"Structures of the Pleiotropic Translational Regulator Hfq and an Hfq-RNA Complex: A Bacterial Sm-like Protein", EMBO J. | | | Borths, K. Locher, A. Lee and D. Rees, "The Structure of Escherichia coli BtuF and Binding to Its Cognate ATP Binding Cassette Transporter", Proc. | | | Parsons, M. Hejazi, K. Tiemann, J. Henning and J. Gardea-Torresdey, "An XAS Study of the Binding of Copper(II), Zinc(II), Chromium(III), and Chromium(VI) to Hops Biomass", Microchem. |
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http://www-ssrl.slac.stanford.edu/pubs/2002pubs.html
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| | Lund University, Doctoral Dissertation |
| | The binding of CTAB to amylopectin was of Langmuir type while the binding to amylose was of the positive cooperative type. | | | The formation of this complex was studied by determining the binding of the cationic surfactant hexadecyltrimethylammonium bromide (CTAB) to amylose and amylopectin using surface tension measurements and measuring the enthalpy of binding with isothermal titration calorimetry (ITC). | | | The enthalpy of binding CTAB to amylopectin was in the same range as the binding of CTAB to amylose. |
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http://www.lub.lu.se/cgi-bin/show_diss.pl/tec_473.html
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| | The Wolf Firm- Mortgage Banking Bookstore |
| | Credit Availability for Condominium and Cooperative Purchase : field hearing before the Subcommittee on Consumer Credit and Insurance of the Committee on Banking, Finance, and Urban Affairs, House of Representatives, One Hundred Third Congress, second session, September 14, 1994 ; Unknown Binding (Hard to Find) | | | Actuarial Soundness of the Federal Housing Administration's Mutual Mortgage Insurance Fund : hearing before the Subcommittee on Housing and Community Development of the Committee on Banking, Finance, and Urban Affairs, House of Representatives, One Hundred Third Congress, second session, June 30, 1994 ; Unknown Binding (Hard to Find) | | | H.R. 3153, The Home Equity Protection Act of 1993: hearing before the Subcommittee on Consumer Credit and Insurance of the Committee on Banking, Finance, and Urban Affairs, House of Representatives, One Hundred Third Congress, second session, March 22, 1994 ; Unknown Binding (Hard to Find) |
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http://www.wolffirm.com/bookstore/title.htm
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| | Cooperative |
| | In biochemistry, a macromolecule that exhibits cooperative behavior has ligand binding characteristics that depend on the amount of ligand bound. | | | Unlike a union, a cooperative may assign different numbers of votes to different members; typically a cooperative is governed proportionally according to each member's level of economic interest in the cooperative. | | | A housing cooperative is a legal mechanism for ownership of housing where residents either own shares (share capital co-op) or have membership and occupancy rights in a not-for-profit continuing co-operative (non-share capital co-op). |
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http://hallencyclopedia.com/Cooperative
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| | Genome-Wide Analyses of Cooperative Transcriptional Regulations with Context-Dependent Probabilistic Models |
| | In some cases, even if the binding score for one single site is weak, the cooperative binding score for both factors is strong enough so that their precise identifications can be achieved. | | | In this study, we have explored genome-wide analyses for cooperative binding activities and context-dependent transcriptional regulations. | | | Recent biological studies have revealed that context dependencies of transcriptional activations among multiple transcription factors are important to understand the mechanisms of complex transcriptional regulations, and the context dependencies enable combinatorial regulations among different types of transcriptional factors (TFs) such as ubiquitous TFs and signal-specific TFs to execute an exponentially larger number of regulatory decisions. |
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http://www.iscb.org/ismb2004/posters/yujiATdna.bio.keio.ac.jp_793.html
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| | Lecture 14: Analysis of Cooperative Binding |
| | Non-cooperative binding to multiple sites (n-sites) is analyzed in exactly the same fashion as to a single site. | | | Quantitative Analysis of Cooperative by the Hill Plot: | | | The Hill plot for oxygen binding to normal adult hemoglobin is shown to the right |
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http://stingray.bio.cmu.edu/~web/bc/Lec/Lec14/lec14.html
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