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Topic: Colon carcinoma



  
 MedlinePlus Medical Encyclopedia: Colon cancer
When cancer arises from the lining of an organ like the large intestine, it is called a carcinoma.
Some evidence suggests that non-steroidal anti-inflammatory drugs (NSAIDs) may help prevent colon cancer, but again, screening is still necessary.
Factors that increase the risk of colon cancer are colorectal polyps, cancer elsewhere in the body, a family history of colon cancer, and ulcerative colitis.
http://www.nlm.nih.gov/medlineplus/ency/article/000262.htm   (1623 words)

  
 eMedicine - Obstruction, Large Bowel : Article by Charles McCabe, MD
Sigmoid colon and rectal tumors cause colonic obstruction much earlier in their development because the colon is narrower and the stool is harder in that area.
Pathophysiology: Colonic obstruction that occurs from the rotating or twisting of the cecum or sigmoid colon normally causes abrupt onset of symptoms.
Sigmoid diverticulitis and a perforated sigmoid secondary to carcinoma are clinically difficult to differentiate.
http://www.emedicine.com/emerg/topic65.htm   (1623 words)

  
 Colon cancer
Eligible patients should be considered for entry into carefully controlled clinical trials comparing various postoperative chemotherapy regimens, postoperative radiation therapy, or biological therapy, alone or in combination.[ 4, 16 ] Refer to PDQ and to CancerNet ( http://cancernet.nci.nih.gov) for information on clinical trials for patients with stage III colon cancer.
Beart RW, Moertel CG, Wieand HS, et al.: Adjuvant therapy for resectable colorectal carcinoma with fluorouracil administered by portal vein infusion: a study of the Mayo Clinic and the North Central Cancer Treatment Group.
For locally advanced disease, the role of radiation therapy with chemotherapy in colon cancer is under clinical evaluation.
http://www.meds.com/pdq/colon_pro.html   (1623 words)

  
 MedlinePlus Medical Encyclopedia: Colon cancer
When cancer arises from the lining of an organ like the large intestine, it is called a carcinoma.
Some evidence suggests that non-steroidal anti-inflammatory drugs (NSAIDs) may help prevent colon cancer, but again, screening is still necessary.
Factors that increase the risk of colon cancer are colorectal polyps, cancer elsewhere in the body, a family history of colon cancer, and ulcerative colitis.
http://www.nlm.nih.gov/medlineplus/ency/article/000262.htm   (1623 words)

  
 Carcinoma in Situ of the Penis in a 76-Year-Old Circumcised Man
Significant past medical history included nonrecurrent bladder carcinoma, left hemicolectomy in 1964 for colon adenocarcinoma, excision of a rectal tubovillous adenoma in 1994, benign prostatic hypertrophy status post-transuretharl resection of prostate, prostatourethritis in 1965, and hepatitis A with jaundice in 1942.
In one study of 11 men with carcinoma in situ of the penis, 10 had been circumcised as infants.
In a Danish study, men with localized squamous cell carcinoma of the penis were 7.81 times as likely to have been circumcised after the newborn period as the general population.
http://www.cirp.org/library/disease/cancer/vanhowe   (1914 words)

  
 Pooled Analysis of Fluorouracil-Based Adjuvant Therapy for Stage II and III Colon Cancer: Who Benefits and by How Much? -- Gill et al. 22 (10): 1797 -- Journal of Clinical Oncology
Moertel CG, Fleming TR, Macdonald JS, et al: Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma.
Iwashyna TJ, Lamont EB: Effectiveness of adjuvant fluorouracil in clinical practice: A population-based cohort study of elderly patients with stage III colon cancer.
therapy for stage II and III colon cancer in an accessible format.
http://www.jco.org/cgi/content/full/22/10/1797   (1914 words)

  
 Carcinoma in Situ of the Penis in a 76-Year-Old Circumcised Man
Significant past medical history included nonrecurrent bladder carcinoma, left hemicolectomy in 1964 for colon adenocarcinoma, excision of a rectal tubovillous adenoma in 1994, benign prostatic hypertrophy status post-transuretharl resection of prostate, prostatourethritis in 1965, and hepatitis A with jaundice in 1942.
In one study of 11 men with carcinoma in situ of the penis, 10 had been circumcised as infants.
Carcinoma in situ of the penis in a 76-year-old circumcised man. J Fam Pract 1997; 44:407-410.
http://www.cirp.org/library/disease/cancer/vanhowe   (1914 words)

  
 Current Status of Sentinel Lymph Node Mapping and Biopsy: Facts and Controversies -- Jakub et al. 8 (1): 59 -- The Oncologist
Sentinel lymph node mapping for carcinoma of the colon: a pilot study.
Atypical ductal hyperplasia and ductal carcinoma in situ as revealed by large-core needle breast biopsy: results of surgical excision.
Ductal carcinoma in situ diagnosed with stereotactic core needle biopsy: can invasion be predicted?
http://theoncologist.alphamedpress.org/cgi/content/full/8/1/59   (1914 words)

  
 Strictures of the Sigmoid Colon: Barium Enema Evaluation -- Blakeborough et al. 220 (2): 343 -- Radiology
Diverticulitis and carcinoma of the colon: differential diagnosis.
and neoplastic strictures of the sigmoid colon persist ( 11).
oblique views of the sigmoid, supine oblique view of the cecum,
http://radiology.rsnajnls.org/cgi/content/full/220/2/343   (1914 words)

  
 Gastrointestinal II, Case 11
Adult colon obstruction: carcinoma (65%), acute diverticulitis (20%), volvulus (5%), other-hernia, intussusception.
Colonic distention and the patient's history indicate a mechanical obstruction.
Marked distention of the cecum and ascending colon to the hepatic flexure is present.
http://www.indyrad.iupui.edu/rtf/teaching/medstudents/gastro2c2.htm   (1914 words)

  
 Colorectal Cancer Treatment, from Avastin.com
Avastin, used in combination with intravenous 5-fluorouracil-based chemotherapy, is indicated for first-line treatment of patients with metastatic carcinoma of the colon or rectum.
In a small study, the incidence of serious or fatal hemoptysis was 31% in patients with squamous histology and 4% in patients with adenocarcinoma receiving AVASTIN as compared to no cases in patients treated with chemotherapy alone.
Serious, and in some cases fatal, hemoptysis has occurred in patients with non-small cell lung cancer treated with chemotherapy and AVASTIN.
http://www.avastin.com   (245 words)

  
 Liver Cancer – Complete medical information associated with this form of cancer on MedicineNet.com
Liver cancer (hepatocellular carcinoma) is a cancer arising from the liver.
The subject of this article is hepatocellular carcinoma, which I will refer to as liver cancer.
When patients or physicians speak of liver cancer, however, they are often referring to cancer that has spread to the liver, having originated in other organs (such as the colon, stomach, pancreas, breast, and lung).
http://www.medicinenet.com/liver_cancer/article.htm   (2261 words)

  
 The Political Graveyard: Politicians Who Died of Colon Cancer
Died, of carcinoma of the sigmoid colon, in North Adams,
Died, of colon cancer, in South Woodstock, Woodstock,
Died, of colon cancer, at George Washington University
http://politicalgraveyard.com/death/colon-cancer.html   (2261 words)

  
 Archives of Pathology & Laboratory Medicine: Focus of signet ring cell carcinoma in an adenoma of the sigmoid colon
Histologic examination of the medium-sized polyp was consistent with an adenoma to carcinoma sequence for signet ring cell carcinoma of the colon, similar to that for the common adenocarcinomas.
Hamazaki M, Kono S, Mimaya J, Ishihara A. Signet ring cell carcinoma in a polyp of the colon: a case report of a six-year-old boy.
Signet ring cell carcinoma has been described in virtually all mucinous organs of the body, most frequently in the stomach,5 but also in the urinary bladder,6 prostate,7 pancreas,8 breast,9 lung,10 and elsewhere.
http://www.findarticles.com/p/articles/mi_qa3725/is_199910/ai_n8874375   (1121 words)

  
 In Vitro and in Vivo Antitumor Activity of Methotrexate Conjugated to Human Serum Albumin in Human Cancer Cells -- Wosikowski et al. 9 (5): 1917 -- Clinical Cancer Research
PC3 (human prostate adenocarcinoma), T84 (human colon carcinoma),
Colo-205 (human colon carcinoma), WiDr (human colon carcinoma),
Intratumoral Administration of Methotrexate Bound to Activated Carbon Particles: Antitumor Effectiveness against Human Colon Carcinoma Xenografts and Acute Toxicity in Mice
http://clincancerres.aacrjournals.org/cgi/content/full/9/5/1917   (1121 words)

  
 Colon Carcinoma, EL SALVADOR ATLAS of Gastrointestinal VideoEndoscopy
Carcinoma of the transverse colon, proximal to the
Colon Carcinoma, EL SALVADOR ATLAS of Gastrointestinal VideoEndoscopy
It has been reported that carcinoma of the colon occurring
http://www.gastrointestinalatlas.com/English/Colon_and_Rectum/Colon_Carcinoma/colon_carcinoma.html   (1121 words)

  
 Archives of the AFIP -- RadioGraphics 1995; 15: 127-146
Some adenocarcinomas of the colon, however, develop not from preexisting adenomas but from a premalignant condition within flat mucosa called dysplasia.
This condition may be partially responsible for the carcinoma seen in patients with the hereditary nonpolyposis colon cancer syndrome.
More common conditions associated with an increased risk of developing colon carcinoma include a personal history of colorectal carcinoma or adenoma; a personal history of ovarian, endometrial, or breast cancer; and a history of colon cancer or adenoma in a first-degree relative.
http://www.rsna.org/REG/publications/rg/afip/privateM/1995/0015/0001/0127/3.htm   (1657 words)

  
 Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells
Together, these results identify molecular mechanisms of silibinin efficacy as a cell cycle regulator and apoptosis inducer in human colon carcinoma HT-29 cells, and justify further studies to investigate potential usefulness of this nontoxic agent in colon cancer prevention and intervention.
Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human colon carcinoma HT-29 cells
Silymarin, a defined mixture of natural flavonoid, has recently been shown to have potent cancer chemopreventive efficacy against colon carcinogenesis in rat model; however, the mechanism of such efficacy is not elucidated.
http://www.nature.com/onc/journal/v22/n51/abs/1207158a.html   (514 words)

  
 Fluorouracil plus Levamisole as Effective Adjuvant Therapy after Resection of Stage III Colon Carcinoma: A Final Report -- Moertel et al. 122 (5): 321 -- Annals of Internal Medicine
Levamisole and fluorouracil for adjuvant therapy of resected colon carcinoma.
Fluorouracil plus Levamisole as Effective Adjuvant Therapy after Resection of Stage III Colon Carcinoma: A Final Report -- Moertel et al.
Surgical adjuvant therapy of large-bowel carcinoma: an evaluation of levamisole and the combination of levamisole and fluorouracil.
http://www.annals.org/cgi/content/full/122/5/321   (4866 words)

  
 Comparative Hepatology Abstract MHC class I expression protects rat colon carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway
MHC class I expression protects CC531s colon carcinoma cells from hepatic NK cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway.
Therefore, using isolated rat hepatic NK cells and the syngeneic colon carcinoma cell line CC531s, we investigated whether this protective role of MHC class I is also operative in hepatic NK cells, and addressed the mechanism of MHC class I protection.
Hepatic natural killer (NK) cells, the most cytotoxic cells of the natural occurring NK cells, are located in the liver sinusoids and are thus in a strategic position to kill arriving metastasising tumour cells, like colon carcinoma cells.
http://www.comparative-hepatology.com/content/1/1/2/abstract   (339 words)

  
 Case of the Month July 2002
Transitional cell carcinoma of the right and left ovary with metastases to the omentum, serosa of the small intestine, serosa/adventitia and wall of rectosigmoid colon, posterior pelvic peritoneum, posterior cervical region and lateral portions of uterus, and spleen.
On the other hand, some experts claim that transitional cell carcinoma of the ovary is a variant of serous carcinoma with pseudopapillary pattern, although the current view favors that transitional cell carcinoma of the ovary is a separate entity.
Immunohistochemical and pathological studies appear to favor that transitional cell carcinoma of ovary is one subtype of ovarian surface epithelial carcinomas, originating in celomic epithelium (as proposed by Austin and Norris 1987), and is different from urothelial carcinoma of urinary bladder.
http://www.hsc.wvu.edu/som/pathology/pathcases/apcases2003/apcasejan03/apcasejan03discussion.htm   (339 words)

  
 stage 3 colon cancer
Stage 0 Colon Cancer (Carcinoma in Situ) Stage I Colon Cancer.
increase the overall survival in patients with TNM stage 3 colon cancer, over those treated by surgery alone, from 46...
role in the adjuvant therapy of stage T4 colon cancer?
http://www.youramazinglife.com/cancercures/11/stage-3-colon-cancer.html   (339 words)

  
 : The AMEDEO Literature Guide
Familial adenomatous polyposis associated with colon carcinoma, desmoid tumour, gallbladder carcinoma, and endometrioid carcinoma: a case report.
MONAGHAN H, Williams AR Brenner tumour with carcinoma in situ: evidence for a spectrum from benign to malignant.
Alteration of PTEN expression in endometrial carcinoma is associated with down-regulation of cyclin-dependent kinase inhibitor, p27.
http://www.amedeo.com/medicine/ovc/histopa.htm   (339 words)

  
 : The AMEDEO Literature Guide
Familial adenomatous polyposis associated with colon carcinoma, desmoid tumour, gallbladder carcinoma, and endometrioid carcinoma: a case report.
MONAGHAN H, Williams AR Brenner tumour with carcinoma in situ: evidence for a spectrum from benign to malignant.
Alteration of PTEN expression in endometrial carcinoma is associated with down-regulation of cyclin-dependent kinase inhibitor, p27.
http://www.amedeo.com/medicine/ovc/histopa.htm   (339 words)

  
 Melanoma immunotherapy by targeted IL-2 depends on CD4+ T-cell help mediated by CD40/CD40L interaction -- Lode et al. 105 (11): 1623 -- Journal of Clinical Investigation
Xiang, R., Lode, H.N., Gillies, S.D., and Reisfeld, R.A. T cell memory against colon carcinoma is long lived in the absence of antigen.
Xiang, R., Lode, H.N., Dreier, T., Gillies, S.D., and Reisfeld, R.A. Induction of persistent tumor-protective immunity in mice cured of established colon carcinoma metastases.
Suppression of human prostate carcinoma metastases in severe combined immunodeficient mice by interleukin 2 immunocytokine therapy.
http://www.jci.org/cgi/content/full/105/11/1623   (339 words)

  
 T cell homeostatic proliferation elicits effective antitumor autoimmunity -- Dummer et al. 110 (2): 185 -- Journal of Clinical Investigation
Thirty-five days after challenge, splenocytes were cultured for 72 hours with either B78D14 melanoma cells (black bars) or MC-38 colon carcinoma cells (white bars).
Ten days after challenge, splenocytes were coincubated with either irradiated B78D14 melanoma cells (filled squares) or irradiated MC-38 colon carcinoma cells (open squares) for 48 hours; a standard 4-hour
The B6-derived B78D14 murine melanoma ( 17) and the MC-38 colon
http://www.jci.org/cgi/content/full/110/2/185   (339 words)

  
 Expression of histo-blood group A antigen increases resistance to apoptosis and facilitates escape from immune control of rat colon carcinoma cells -- Marionneau et al. 12 (12): 851 -- Glycobiology
Expression of histo-blood group A antigen increases resistance to apoptosis and facilitates escape from immune control of rat colon carcinoma cells -- Marionneau et al.
Expression of histo-blood group A antigen increases resistance to apoptosis and facilitates escape from immune control of rat colon carcinoma cells
A and B histo-blood group antigens are present on carcinoma
http://glycob.oupjournals.org/cgi/content/abstract/12/12/851   (339 words)

  
 MedlinePlus Medical Encyclopedia: Colon cancer
When cancer arises from the lining of an organ like the large intestine, it is called a carcinoma.
Some evidence suggests that non-steroidal anti-inflammatory drugs (NSAIDs) may help prevent colon cancer, but again, screening is still necessary.
Factors that increase the risk of colon cancer are colorectal polyps, cancer elsewhere in the body, a family history of colon cancer, and ulcerative colitis.
http://www.nlm.nih.gov/medlineplus/ency/article/000262.htm   (1623 words)

  
 NordiQC
Among germ cell tumours, CEA is seen in most cases of embryonal carcinoma but rarely in the other types.
Among neuroendocrine tumours, CEA is found in the large majority of medullary thyroid carcinoma (Fig 2D), less often and more weakly expresed in carcinoid tumour, neuroendocrine carcinoma and rarely in small cell carcinoma.
In normal adult tissue, CEA is expressed in the apical border and, to a lesser extent in the cytoplasm, of the columnar cells of colon (Fig.
http://www.nordiqc.org/Epitopes/CEA/CEA.htm   (1623 words)

  
 carcinoma: Definition and Much More From Answers.com
The UICC/AJCC TNM system is often used, however for some common tumours, classic staging methods (such as the Dukes classification for colon cancer) are still used.
Carcinomas, like all cancers, are staged according to the extent of disease.
Sometimes a tumour is referred to by the presumptive organ of the primary (eg carcinoma of the prostate) or the putative cell of origin (hepatocellular carcinoma, renal cell carcinoma).
http://www.answers.com/main/ntquery?method=4&dsid=2222&dekey=Carcinoma&gwp=8&curtab=2222_1&sbid=lc01a   (1623 words)

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