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| | IASP Newsletter Technical Corner: Pain, Its Perception and Pain Imaging |
 | | The descending connections of the anterior cingulate cortex to the medial thalamic nuclei and to the peri-aqueductal gray in the brain stem suggest that this system may also be involved in the modulation of reflex responses to noxious stimuli. | | | Support for the idea that the anterior cingulate processes the affective components of pain comes from PET studies of patients with atypical facial pain where psychogenic mechanisms are thought to contribute to the perseveration of the pain. | | | The anterior cingulate cortex is an extensive area of the limbic cortex overlying the corpus callosum and is involved in the integration of cognition, affect, and response selection (Dovinsky et al. |
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http://www.iasp-pain.org/TC97MayJune.html
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| | The Krasnow Institute: Abstracts |
| | A large body of clinical and functional imaging data support the crucial role of the ventral part of anterior cingulate cortex in emotional experience. | | | There is some degree of overlap between the emotional and cognitive components of the anterior cingulate, and they are extensively interconnected. | | | Recent evidence from EEG and fMRI indicates that the anterior cingulate is particularly active when the subject recognizes that he or she has just committed an error in one of these difficult tasks. |
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http://www.gmu.edu/departments/krasnow/abstracts_frames/abs00/allm0010.htm
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| | Clarkson University - Psychology Department |
| | Physiological basis of pain perception and pain control in humans, and the role of the anterior cingulate cortex in pain processing. | | | Recently we developed a means of isolating and quantifying pain-related activity in the anterior cingulate cortex, which is a brain area located in medial part of the frontal lobe. | | | The anterior cingulate cortex has been shown in several other studies to become active whenever a painful stimulus is given. |
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http://www.clarkson.edu/psychology/faculty/dowman.html
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| | Anterior Cingulate in Bipolar Disorder -- Neurotransmitter.net |
| | METHODS: Serial assessments of anterior cingulate cortex choline and myo-inositol metabolism were performed in nine subjects with bipolar disorder, taking either lithium or valproate, and 14 controls. | | | The location of central electrodes over the cingulate cortex may indicate that pretreatment cingulate activity is associated with response to ECT. | | | Localized gray matter deficits in bipolar subjects were found in the medial temporal lobe, orbito-frontal cortex, and the anterior cingulate, confirming and extending earlier studies. |
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http://www.neurotransmitter.net/bipolaracc.html
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| | Stuart Derbyshire homepage |
| | Region 1 is anterior midcingulate cortex (aMCC) that may have a particular role in processing the affect associated with pain. | | | Region 3 is the posterior cingulate cortex that is only occasionally activated by pain and we are still in the process of trying to figure what it is doing. | | | This image is a simplification of the thalamic projections believed to mediate the experience of pain. |
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http://www.geocities.com/sderbysh/stuart_page.html
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| | Chronic Lithium Treatment Decreases Neuronal Activity in the Nucleus Accumbens and Cingulate Cortex of the Rat |
| | Devinsky O, Morrell MJ, Vogt BA (1995): Contributions of anterior cingulate cortex to behavior. | | | To our knowledge, this is the first report of the use of CO brain maps to explore the neural pathways involved in the pharmacotherapy of psychiatric disorders. | | | The findings of this study support the cingulate cortex as a site of action of lithium's mood stabilizing effects. |
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http://www.nature.com/cgi-taf/dynapage.taf?file=/npp/journal/v21/n2/full/1395300a.html
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| | Research Interests of Jonathan D. Cohen |
| | Context, cortex and dopamine: A connectionist approach to behavior and biology in schizophrenia. | | | prefrontal) and evaluative (e.g., cingulate) functions evident in our work on cognitive control, and an appreciation of the fact that few, if any, aspects of real world behavior are governed exclusively by one form of processing or the other. | | | A preliminary theory of the interactions between prefrontal cortex and hippocampus that contribute to planning and prospective memory. |
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http://www.csbmb.princeton.edu/ncc/jdc.html
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| | [No title] |
| | Future studies evaluating whether the cingulate causes poor task performance during pain or its activity is an attempt to resolve the conflict resulting from pain during the task performance are warranted. | | | Indeed, our study here suggests that the anterior cingulate may be involved in selecting whether the subject should respond to his pain or continue with his task. | | | Our results also indicate that the anterior cingulate cortex is involved in the interaction between pain and task performance. |
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http://home.uchicago.edu/~msgoyal/PainCingulateManu.doc
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| | Welcome to the Bush Lab |
| | Cognitive and emotional influences in anterior cingulate cortex. | | | Determining the nature of cingulate sub-territories is vital to understanding the neurobiology of neuropsychiatric disorders, as cingulate subregions play crucial roles in cognitive, motor, and emotional processes. | | | My research seeks to use functional neuroimaging in conjunction with cognitive, motor, and emotional activation paradigms in novel ways to study cingulate cortex function in normal cognitive processing and neuropsychiatric disorders--especially attention-deficit/hyperactivity disorder (ADHD). |
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http://www.nmr.mgh.harvard.edu/BushLab
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| | cingulat |
| | "It is of interest that stimulation and ablation of the cingulate gyrus result in a diverse range of emotional experiences corresponding to those described. | | | "Its location makes the cingulate cortex an excellent candidate for the brain's emotional control centre, which is what it seems to be" (Carter 1998:101). | | | 302, No. 5643), suggest links between emotions and the anterior cingulate cortex. |
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http://members.aol.com/nonverbal3/cingulat.htm
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| | DukeMedNews Brain Area Identified That Weighs Rewards |
| | The researchers chose to study the role of the posterior cingulate cortex in making decisions about eye movement, because the visual system and the neural control of the eye muscles is very well understood, said Platt. | | | Also, said Platt, although he and his colleagues used eye movement as their experimental indicator of response, the posterior cingulate cortex has been linked to control of other muscle movements, suggesting that it plays a broader role in decision-making about actions. | | | For example, by precisely stimulating neurons in the region at different points in the judgment process, the researchers hope to determine whether they can affect the ability of a monkey to choose the right eye movements to receive a reward. |
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http://dukemednews.org/news/article.php?id=7266
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| | Publications & Presentations |
| | Neuroanatomical correlates of error-related activity in the anterior cingulate cortex: Evidence from single-subject analyses. | | | Errors and conflict but not error feedback engage the anterior cingulate cortex during event-related fMRI: Implications for performance monitoring in the human brain. | | | Separating semantic conflict from response conflict in the Stroop task: Behavioral and functional MRI evidence. |
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http://www.pitt.edu/AFShome/v/e/veen/public/html/pubs.htm
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| | Publications - Gabriel Lab |
| | Interaction of the laminae of cingulate cortex and the anteroventral thalamus during behavioral learning. | | | Unit activity in limbic cortex and antero- ventral thalamus during acquisition and overtraining of discriminative avoidance behavior in rabbits. | | | Effects of anterior thalamic lesions on discriminative avoidance behavior and neuronal activity in the cingulate cortex, |
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http://soma.npa.uiuc.edu/labs/mgabriel/publications.php
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| | Glutamate and Unipolar Depression Research -- Neurotransmitter.net |
| | At this time, a considerable amount of new information is converging--derived from animal models of mood disorders, genetics, basic behavioral research, and neuroscience. | | | In this study metabolic changes within the DLPFC of severely depressed patients before and after electroconvulsive therapy (ECT) were evaluated by proton STEAM spectroscopy (1H-MRS). | | | This change is delayed and occurs only in the cortex. |
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http://www.neurotransmitter.net/depressionglutamate.html
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| | Brain Explorer - cingulate gyrus |
| | The cingulate gyrus forms part of the limbic system, which is associated with mood and emotions. | | | A prominent gyrus (a ridge of the infolded cerebral cortex) found near the mid-sagittal plane of the brain, above the corpus callosum. |
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http://www.brainexplorer.org/glossary/cingulate_gyrus.shtml
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| | Localization of area prostriata and its projection to the cingulate motor cortex in the rhesus monkey. |
| | This linkage between cortex bordering V1 and cortex giving rise to a component of the corticofacial and corticospinal pathways demonstrates a more direct visuomotor route than visual association projections coursing laterally. | | | Cytoarchitectural analysis confirmed the identity of area prostriata and further clarified its extent and borders with the parasubiculum of the hippocampal formation rostrally, and V1 of the visual cortex caudally. | | | It has attracted interest as a separate visual area and progenitor for the cortex of this modality. |
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http://brainmeta.com/neuroanat/a63.html
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| | Research - Gabriel Lab |
| | The anterior cingulate cortex has been shown to play a very important role in the early stages of learning of our discriminative avoidance task while the posterior cingulate cortex is important in the later stages of learning. | | | Evidence for this is that lesions of the anterior or posterior cingulate cortex alone lead to early or late learning deficits, respectively. | | | This study tested the hypothesis that lesions of the posterior cingulate cortext in rabbits exposed to cocaine in utero will have a more severe learning deficit than that seen with cocaine exposure alone due to the inability of the posterior cingulate cortex to compensate for the abnormal functioning of the anterior cingulate cortex. |
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http://soma.npa.uiuc.edu/labs/mgabriel/research.php?doc=0004
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| | The Human Brain Conference 2002 - Speakers and Abstracts |
| | Although cytoarchitectural studies identified many cingulate areas, limbic theories suggested it was one entity. | | | Opiate and serotonergic drugs influence affect and are active in pACC. | | | Since citalopram binding to the serotonin transporter is particularly high in pACC, this may explain the effectiveness of antidepressants in alleviating mood and pain disorders. |
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http://www.thehumanbrain.org/Vogt.htm
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| | Poster Session Abstracts |
| | The brains of all patients were staged for the severity of neurofibrillary changes according to the Braak method and divided into 3 groups from least severe to most severe: transentorhinal, limbic and isocortical. | | | Our results suggest that allocortical cingulate regions display a greater vulnerability to AD brain lesions than the isocortical regions. | | | In this study, the distribution of the brain lesions characteristic of Alzheimer's disease (AD) was studied in the cingulate cortex of normal aged and AD patients. |
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http://www.medlib.iupui.edu/faculty/scs/p101.html
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| | WOBIB: 39 - Maddock, et al. (2003) Posterior cingulate ... |
| | The findings are consistent with the suggestion that this region may mediate interactions of emotional and memory-related processes. | | | Temporal and spatial dynamics of human forebrain activity during heat pain: analysis by positron emission tomography. | | | The results also extend prior findings that evaluating emotional words consistently activates the subgenual cingulate cortex, and suggest a means of probing this region in patients with mood disorders. |
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http://hendrix.imm.dtu.dk/services/jerne/brede/WOBIB_39.html
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| | anterior cingulate cortex: Information From Answers.com |
| | The ACC appears to play a role in a wide variety of autonomic functions, such as regulating heart rate and blood pressure, and is vital to cognitive functions, such as reward anticipation, decision-making, empathy, and emotion. | | | Neuroscientists indicate the dorsal anterior cingulate cortex is primarily related to rational cognition while the ventral is more related to emotional cognition. | | | Whereas most funded research is concentrated on reduced task focus - often diagnosed subjectively as attention deficit hyperactivity disorder (ADD) - recent research has revealed that heightened ACC activity (generally associated with reduced dopamine utilization) reduces capacity to learn how to use visual cues for anticipating rewards [1] (http://www.msnbc.msn.com/id/5673747/). |
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http://www.answers.com/topic/anterior-cingulate-cortex
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| | NPR : Brain Region May Give Early Warning of Risk |
| | A new theory suggests that the anterior cingulate cortex, described by some as part of the brain's "oops center," may serve as an early warning system -- working at a subconscious level to help us recognize and avoid high-risk situations. | | | Some theories suggest that what the cingulate actually detects is this state of conflict. | | | All Things Considered, February 17, 2005 · Researchers say that the part of the brain that recognizes our mistakes also acts as an early warning system to keep us from screwing up. |
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http://www.npr.org/templates/story/story.php?storyId=4503396
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| | Axons of early generated neurons in cingulate cortex pioneer the corpus callosum. |
| | We conclude that the two major efferent pathways from cortex, the corpus callosum and the internal capsule, are pioneered by developmentally and spatially distinct populations of early generated cortical neurons. | | | Previous studies have shown that the first cortical axons to grow through the internal capsule, the pathway from cortex to its subcortical targets, are extended by subplate neurons, which are the earliest generated neurons in the neocortex. | | | Here, we characterize the origin of the first axons to project through the other major efferent pathway of the cortex, the midline corpus callosum, which connects the two cortical hemispheres. |
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http://www.arclab.org/medlineupdates/abstract_7965064.html
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| | cingulate cortex: Information From Answers.com |
| | The cingulate cortex is part of the brain and situated roughly in the middle of the cortex. | | | Four Regions of Cingulate Cortex and Disease Vulnerability (http://www.thehumanbrain.org/Vogt.htm), Brent A. Vogt. | | | The areas 26, 29 and 30 are usually referred to as the retrospenial areas. |
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http://www.answers.com/topic/cingulate-cortex?hl=cingulate
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| | Nielsen, Balslev, Hansen: Mining Posterior Cingulate |
| | A research study on text mining and automated analysis of the functions of the posterior cingulate area of the human brain. | | | Brede Neuroinformatics Toolbox are used to analyze the data. | | | We present a general method for automatic meta-analyses in neuroscience and apply it on text data from published functional imaging studies to extract main functions associated with a brain area --- the posterior cingulate cortex. |
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http://hendrix.imm.dtu.dk/staff/fnielsen/Nielsen2003Posterior.html
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| | HABITUATION DECREASES THE EXPRESSION OF FOS IN THE STRIATUM AND CINGULATE CORTEX OF NOVELTY-SHUTTLED RATS |
| | The decrease in FLI was not correlated with locomotor behavior suggesting that repeated exposure to novel environments results is responsible for the reduction of striatal and cingulate cortex FLI and that this effect is not due to a reduction in locomotor activity. | | | The present study examined the effects of repeated NS on FLI in the striatum and the cingulate cortex. | | | Male rats were placed into one of three groups; 1) animals sacrificed in their homecage (HC), 2) animals sacrificed after their first day of NS (Novelty), and 3) animals sacrificed after their fifth day of NS (Habituation). |
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http://www.wheaton.edu/psychology/undergrad/faculty/wms/research/SFN2001abs.htm
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| | Cingulate cortex of the rhesus monkey: II. Cortical afferents. |
| | The following projections were observed both to and within posterior cingulate cortex. | | | Areas 24a and 24b received afferents from areas 25 and 23b of cingulate cortex, but most were from frontal and temporal cortices. | | | The origin and termination of these connections were expressed in a number of different laminar patterns. |
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http://brainmeta.com/neuroanat/a101.html
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| | Serotoninergic neurites in senile plaques in cingulate cortex of aged nonhuman primate. |
| | Intricate and distinct patterns of serotoninergic processes were seen in anterior and posterior segments of cingulate cortex (Brodmann areas 24 and 23). | | | In these regions of cortex, many multivaricose serotonin-immunoreactive axonal swellings were identified, and some of these immunostained neurites were associated with deposits of amyloid. | | | In immunocytochemical studies, a polyclonal antiserotonin antibody was used to visualize fibers within the cingulate cortex of young and aged rhesus monkeys. |
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http://www.arclab.org/medlineupdates/abstract_2919367.html
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| | cingulate sulcus - definition of cingulate sulcus in the Medical dictionary - by the Free Online Medical Dictionary, ... |
| | cingulate sulcus - definition of cingulate sulcus in the Medical dictionary - by the Free Online Medical Dictionary, Thesaurus and Encyclopedia. | | | This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional. | | | A fissure on the mesial surface of the cerebral hemisphere, bounding the upper surface of the cingulate gyrus, curving up to the superomedial margin of the hemisphere, and bordering the paracentral lobule posteriorly. |
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http://medical-dictionary.thefreedictionary.com/cingulate+sulcus
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| | Journal of Vision - World-centered spatial representations in posterior cingulate cortex, by Dean & Platt |
| | Posterior cingulate cortex (CGp) is strongly connected with both visual and oculomotor circuitry, and dysfunction of this area has been linked to spatial disorientation. | | | These observations suggest that CGp might integrate visual and oculomotor data to compute spatial representations used in orienting and navigation. | | | Journal of Vision - World-centered spatial representations in posterior cingulate cortex, by Dean and Platt |
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http://www.journalofvision.org/4/8/263
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| | New Publications at Beckman Institute |
| | Erickson, K.I., Milham, M.I., Colcombe, S.J., Kramer, A.F., Banich, M.T., Webb, A. and Cohen, N.J. (2004), “Behavioral Conflict, Anterior Cingulate Cortex, and Experiment Duration: Implications of Diverging Data,” Human Brain Mapping, in press. |
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http://www.beckman.uiuc.edu/news/pubs/index.html
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