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| | Northwestern Memorial Hospital - Exceptional Care in the Heart of Chicago |
 | | Although careful monitoring after the removal of hydatidiform mole or termination of pregnancy may not prevent the development of choriocarcinoma, it is essential in early identification of the condition, which improves outcome. | | | Hydatiform mole is a condition which develops when a pregnancy has many complications. | | | After an initial diagnosis, a careful history and examination are done to rule out metastasis (spread to other organs). |
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http://www.nmcancer.com/nmh/adam/adamencyclopedia/HIEArticles/001496.htm
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| | Choriocarcinoma - Talk Medical |
| | When the cancer has spread to the brain, radiation therapy may be given to the brain. | | | Choriocarcinoma is not contagious and poses no risk to others. | | | Treatment of choriocarcinoma can be very effective, particularly in its early stages. |
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http://www.talkmedical.com/diseases-disorders/213/Choriocarcinoma
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| | Primary choriocarcinoma in the anterior mediastinum in a man: a case report and review of the literatures |
| | Based on these findings, a diagnosis of primary choriocarcinoma in the anterior mediastinum was made, but chemotherapy and surgery were rejected and the patient was discharged by his relatives. | | | An international analysis showed that the median age of 635 patients with EGCTs was 30 years with a range of 14 years to 79 years.£Û4£Ý The most common symptoms of EGCTs are dyspnea and chest pain. | | | In any case, the level of ¦Â-HCG and chest X-ray or CT are important during the period of follow-up. |
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http://www.cmj.org/information/full.asp?id=1825
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| | eMedicine - Testicular Choriocarcinoma : Article by John W Davis, MD |
| | In pure choriocarcinoma, a bone scan can probably be omitted in the absence of bone pain. | | | Pure choriocarcinoma, an extremely rare variant comprising less than 1% of NSGCT, is not as sensitive to chemotherapy as mixed NSGCT. | | | Testicular pain with or without radiating pain to the groin and abdomen is possible but is more consistent with epididymitis. |
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http://www.emedicine.com/med/topic362.htm
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| | Medical Oncology: A Comprehensive Review - Gestational Trophoblastic Tumors |
| | Several investigators have examined the use of multimodality therapy in this group of patients. | | | Weed JC, Hammond CB: Cerebral metastatic choriocarcinoma: Intensive therapy and prognosis. | | | This subset represents a significant fraction of patients who die of the disease. |
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http://www.cancernetwork.com/textbook/morev23.htm
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| | ApolloLife - Education Material |
| | This may not prevent the development of choriocarcinoma, but it does help reduce the risk. | | | Always consult your doctor before undertaking any therapy. | | | Choriocarcinoma is a cancer that develops in the uterus. |
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http://channels.apollolife.com/show.asp?NewAid=8349
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| | CancerLink - Gestational Trophoblastic Disease |
| | At this point the patient is reexamined, a chest x-ray obtained and perhaps a scan of the liver. | | | This is a term that includes several conditions that are associated with the results of a pregnancy. | | | They can develop into choriocarcinoma which is a virulent cancer. |
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http://www.njh.u-net.com/cgest.html
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| | Gestational Trophoblastic Neoplasms - October 2001: 710200 |
| | Thus, the biological identity of the new human being does not depend on the sojourn in the uterus; the preimplantation embryo is the same individual of the human species as the adult, into whom the embryo can in principle develop. | | | AB - A retrospective analysis of clinicopathological data of 10 patients with clinically unsuspected cerebral metastatic choriocarcinoma was carried out. | | | However, such patients are often immunocompromised and cytotoxic agents may further compromise immunity. |
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http://www.acor.org/cnet/710200.html
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| | Getstation THrophoblastic diseas |
| | Choriocarcinoma: Is the full fledge malignant variant, which is treated with chemotherapy. | | | Choriocarcinoma can develop following any oneof these circumstances: | | | Choriocarcinoma: Is the full fledge malignant variant, which |
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http://www.tirgan.com/gtd.htm
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| | Lola's Story, Gestational Trophoblastic Disease - Choriocarcinoma EyesOnThePrize.org |
| | I quickly learned the hard way, that Gestational Trophoblastic Disease is a term that includes several malignant conditions that are associated with pregnancy: molar pregnancy, invasive mole, metastatic mole and gestational choriocarcinoma (korio carcinoma). | | | I can only hope that during my lifetime I can pass my support and experience to help some else with a gyn/cancer or Gestational Trophoblastic Disease. | | | Lola's Story, Gestational Trophoblastic Disease - Choriocarcinoma |
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http://www.eyesontheprize.org/stories/lola.html
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| | choriocarcinoma I don't have timeto Die! - |
| | Peter G. Rose, MD Bagshawe and Brooks(1) first reported that choriocarcinoma could be found at autopsy in the pulmonary tree of patients who died with pulmonary hypertension. | | | My story of how Choriocarcinoma affected my life | | | The clinical, biochemical, and radiologic findings as well as the dramatic response to chemotherapy in the current case provide support to the diagnosis of cerebrovascular embolic disease. |
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http://www.angimarek.com/chorio/DrRose.htm
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| | Choriocarcinoma |
| | For instance, some people find activities such as yoga, massage, music therapy, meditation, prayer, or mild physical exercise helpful. | | | Choriocarcinomas are usually referred to an oncologist, a doctor who specializes in cancer treatment. | | | Choriocarcinomas are usually treated by surgical removal of the tumor and chemotherapy. |
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http://myhealth24.com/pacificare/Atoz/ency/choriocarcinoma.jsp
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| | World Journal of Surgical Oncology Full text Unusual presentation of choriocarcinoma |
| | Choriocarcinoma is an aggressive neoplasm arising in the body of the uterus. | | | On the other hand choriocarcinoma is rare but one of the most malignant neoplasms arising in the body of uterus. | | | Trophoblastic diseases comprise a variety of biologically interrelated conditions which form a clinical spectrum consisting of four distinct clinical pathological entities like (1) molar pregnancy (2) invasive mole (3) placental site trophoblastic tumours and (4) choriocarcinoma [ 1 ]. |
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http://www.wjso.com/content/1/1/4
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| | Chin Med J (Taipei) 1997;59:320-4. (Refractory Choriocarcinoma) |
| | This combination therapy offers a great chance to treat very serious refractory choriocarcinoma. | | | The VIP regimen may be considered as an effective protocol to cure refractory choriocarcinoma. | | | The VIP Regimen Effective Treatment to Refractory Choriocarcinoma: A Case Report |
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http://www.vghtpe.gov.tw/~jcma/5905/590509.htm
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| | Gestational Trophoblastic Disease |
| | Furthermore, loss of p27kip1 in malignant trophoblast may represent a necessary step in the development of choriocarcinoma. | | | Metastases especially to brain and liver can occur in 20-60% of patients | | | Abnormal trophoblastic proliferations may be mediated through interactions of Cdk-2, E2F-1, cyclin E, and p27kip1. |
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http://www.thedoctorsdoctor.com/diseases/gestationaltrophoblasticdisease.htm
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| | Sheffield Trophoblastic Disease Centre - Guide to Trophoblastic Disease |
| | Even a tiny amount of mole anywhere in the body can grow quickly and cause problems, so active treatment of this condition is very important. | | | CHORIOCARCINOMA: A very rare but curable form of cancer where the placenta becomes malignant. | | | This can arise from a molar pregnancy or an otherwise normal pregnancy or miscarriage. |
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http://www.shef.ac.uk/chorio/tdpib/pibwi.html
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| | hCG Reference Service - hCG, phantom hCG, hCG Reference Service, trophoblast |
| | It was started to address these issues, aid in the interpretation of irregular or conflicting hCG results, help interpret low levels of hCG in non-pregnant individuals, and in individuals with trophoblast disease (hydatidiform mole and choriocarcinoma). | | | A relatively large number of patient have been and are still being needlessly treated with chemotherapy and received a hysterectomy or other surgical procedures based solely on false or phantom hCG levels (see references 7-13, below) ( click here to see potential sources of hCG in and outside of pregnancy). | | | As such, according to our databases, even hysterectomy is ineffective in completely abating quiescent diseases. |
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http://www.hcglab.com
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| | Archives of the AFIP -- RadioGraphics 1996; 16: 131-148 |
| | Those cases that arise after complete hydatidiform mole are nearly all cured by chemotherapy (in contrast to the others, which have a less favorable prognosis). | | | Alternatively, the better prognosis may also result because patients with complete hydatidiform mole are identified to be "at risk" earlier than general postpartum patients, in whom the diagnosis would be relatively unsuspected ( 3, 11). | | | As stated, half of all cases of choriocarcinoma occur in patients with prior complete hydatidiform mole who would be undergoing careful follow-up for the purpose of early detection of just such a lesion. |
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http://rsna.org/REG/publications/rg/afip/privateM/1996/0016/0001/0131/8.htm
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| | Cancer Information, Research, and Treatment for all Types of Cancer OncoLink |
| | A comparative study of transvaginal ultrasonography and pelvic arteriogram in assessment of patients with gestational trophoblastic | | | A clinical diagnosis of metastatic gestational choriocarcinoma involving the choroid and lung was made. | | | CONCLUSION: This is a very rare case of the successful treatment of gestational choriocarcinoma metastatic to the choroid using systemic chemotherapy alone. |
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http://www.oncolink.upenn.edu/types/article.cfm?c=6&s=22&ss=176&id=7883
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| | choriocarcinoma on Encyclopedia.com |
| | Publication: Southern Medical Journal; Author: Altiparmak, Mehmet Riza Pamuk, Omer Nuri Pamuk, Gulsum Emel Ozbay, Gulsen ; Source: MAGAZINES | | | Membranous glomerulonephritis in a patient with choriocarcinoma: case report. | | | Primary testicular choriocarcinoma with pulmonary metastases presenting as ARDS. |
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http://www.encyclopedia.com/html/X/X-chorioca.asp
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| | News - A Review of Diagnosis, Treatment, and Prognosis in Infantile Choriocarcinoma |
| | Approximately 18% of infants achieved a sustained remission after multi-agent cisplatinum-based chemotherapy and tumour resection. | | | A Review of Diagnosis, Treatment, and Prognosis in Infantile Choriocarcinoma | | | Because prognosis of children with infantile choriocarcinoma may be improved by early diagnosis and appropriate treatment, Martin E. Blohm and Ulrich Göbel, MD, of Heinrich Heine University Children's Hospital in Dusseldorf, recently published a retrospective literature review to alert paediatricians to clinical symptoms and therapeutic options. |
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http://www.docguide.com/gpc.nsf/doc?CreateDocument=&n=22&l=PE&u=/news/content.nsf/news/8525697700573E1885256DEA0037A15B?OpenDocument&c=Anaemia&count=10
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| | CHEST: Does primary pulmonary choriocarcinoma really exist? - Letter to the Editor |
| | There is no comment concerning the technique (physical examination? | | | Finally, it is well documented that many nontrophoblastic malignancies may produce and/or express ectopic placental hormones, including primary conventional lung carcinomas. | | | Although a weak cytoplasmic immunostaining for [beta]-human chorionic gonadotrophin was noted, such tumors have been classified as pleomorphic carcinomas with choriocarcinoma-like features in accordance to the 1999 World Health Organization classification of lung tumors, (4) but not as primary choriocarcinomas of the lung. |
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http://findarticles.com/p/articles/mi_m0984/is_1_123/ai_97115968
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| | Tumor Markers |
| | In patients with choriocarcinoma who have had a hysterectomy and oophorectomy, the presence of beta-HCG will confirm the patient has residual cancer that requires further treatment. | | | Beta-HCG is also used as a marker postoperatively to monitor residual tumor and the effectiveness of therapy. | | | In patients with testicular cancer who have had an orchiectomy, the presence of beta-HCG will confirm the patient has residual cancer that requires further treatment. |
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http://training.seer.cancer.gov/module_diagnostic/unit03_tumor_markers.html
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| | Introduction: Choriocarcinoma - WrongDiagnosis.com |
| | Treatments for Choriocarcinoma: Various information is available about treatments available for Choriocarcinoma, or research treatments for other diseases. | | | Researching symptoms of Choriocarcinoma: Further information about the symptoms of Choriocarcinoma is available including a list of symptoms of Choriocarcinoma, or alternatively return to research other symptoms in the symptom center. | | | Causes of Choriocarcinoma: Research more detailed information about the causes of Choriocarcinoma, other possibly hidden causes of Choriocarcinoma, or other general information about Choriocarcinoma. |
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http://www.wrongdiagnosis.com/c/choriocarcinoma/intro.htm
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| | Gestational Tumors |
| | Gestational choriocarcinomas are highly responsive to chemotherapy and patients are typically cured. | | | Tumors arising from the placental chorionic villi (derived from the fetus) are generically termed "gestational trophoblastic disease." The benign form of this disorder is hydatidiform mole, and affected pregnancies are referred to as "molar pregnancies." The malignant counterpart is choriocarcinoma. | | | Since choriocarcinoma may arise in molar pregancies (1 in 40 molar pregnancies), moles should be viewed with suspicion. |
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http://www.mcl.tulane.edu/classware/pathology/medical_pathology/prenatal/05tumors.html
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| | Choriocarcinoma -- eCureMe.com |
| | Choriocarcinoma is a cancer that originates in trophoblastic cells of the placenta (afterbirth). | | | HCG levels are used to track the effectiveness of treatment for all types of gestational trophoblastic neoplasia. | | | Cure rates are high for choriocarcinoma, if treated aggressively. |
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http://www.ecureme.com/especial/obgyn/Choriocarcinoma.asp
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| | Uterine Cancer News |
| | Now, Dutch researchers report that radiation therapy may not be necessary for many women with stage I disease. | | | Therefore, women in whom HCG is detected after pregnancy are often treated for choriocarcinoma with surgical removal of the uterus and/or chemotherapy. | | | Now, researchers in New Mexico caution that false-positive blood tests for HCG are possible and may result in unnecessary treatment in women who, in fact, do not have choriocarcinoma. |
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http://patient.cancerconsultants.com/uterine_cancer_news.aspx
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| | Endometrial Cancer |
| | Despite suction and curretage persisting hCG : choriocarcinoma (20% of patients) |
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http://webpages.charter.net/saabrio/UROGEN_Gestational_Trophoblastic_Disease.htm
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| | National Cancer Institute - Gestational Trophoblastic Tumor Treatment |
| | Choriocarcinoma can spread from the uterus to other parts of the body. | | | This type of cancer occurs in women during the years when they are able to have children. | | | Hydatidiform mole does not spread outside of the uterus to other parts of the body. |
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http://www.cancer.gov/cancerinfo/pdq/treatment/gestationaltrophoblastic/patient
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| | Korean Journal of Radiology |
| | Intrarenal pseudoaneurysms complicating renal choriocarcinoma metastases: treatment with coil embolization. | | | In conclusion, the clinical and imaging presentation of primary choriocarcinoma can be absent or subtle, possibly due to spontaneous regression of the tumor itself, and only a metastatic lesion presents as either a hypervascular liver mass at imaging studies, or progressive anemia or intra-abdominal hemorrhage, clinically. | | | The angiographic findings for metastatic choriocarcinoma of the brain (6, 7) and kidney (8) are reported in the literature and include prominent hypervascularity, arteriovenous shunt, oncocytic or fusiform aneurysm, and thrombosis. |
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http://www.kjronline.org/abstract/view_articletext.asp?year=2002&page=260
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| | Infantile Choriocarcinoma |
| | The management of the other six successfully treated children is summarised in the table I. In most cases of successfully treated infantile choriocarcinoma the diagnosis was made from liver biopsy. | | | Infantile choriocarcinoma is an extremely rare form of gestational choriocarcinoma, with 26 published case reports and only seven successfully treated children (1). | | | There are no established treatment protocols and the prognosis has usually been very poor with diagnosis made at post mortem in many cases. |
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http://isstd.org/journal/new_page_8.htm
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| | Choriocarcinoma |
| | Whether women with PMD need human chorionic gonadotrophin (hCG) follow-up is debated. | | | All patients, with suspected PM should be reviewed and if confirmed, need hCG follow-up. | | | This was identified as choriocarcinoma in 3 cases. |
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http://www.mdbrowse.com/Speciality/Oncology/Choriocarcinoma.htm
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| | Fluid Shear Stress Reduces 11{beta}-Hydroxysteroid Dehydrogenase Type 2 -- Lanz et al. 37 (1): 160 -- Hypertension |
| | Regulation of 11beta-hydroxysteroid dehydrogenase type 2 by progesterone, estrogen, and the cyclic adenosine 5'-monophosphate pathway in cultured human placental and chorionic trophoblasts. | | | The hormone-synthesizing trophoblastic cell in vitro: a model for cancer research and placental hormone synthesis. | | | Hardy DB, Pereria LE, Yang K. Prostaglandins and leukotriene B4 are potent inhibitors of 11beta-hydroxysteroid dehydrogenase type 2 activity in human choriocarcinoma JEG-3 cells. |
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http://hyper.ahajournals.org/cgi/content/full/37/1/160
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| | choriocarcinoma - I don't have time todie -Favorites |
| | Choriocarcinoma is what happens when Gestational trophoblastic disease metastasizes from the uterus, it metastasized to my brain, causng a stroke, and 2 subsequent brain hemorhages. | | | I developed choriocarcinoma after a molar pregnancy, causing all of the problems listed in this article. | | | choriocarcinoma - I don't have time todie -Favorites |
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http://www.angimarek.com/chorio/cancer.htm
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| | Search Results for choriocarcinoma - Encyclopædia Britannica |
| | Brief information on the causes, symptoms, diagnosis, prognosis, prevention, and cure of this malignant type of tumour arising from the trophoblast. | | | The reasons that normal chorionic cells undergo cancerous change, with exaggeration of their natural and... | | | Choriocarcinoma is a rare, extremely malignant type of tumour arising from the trophoblast. |
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http://www.britannica.com/search?query=choriocarcinoma&submit=Find&source=MWTAB
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| | CD9 is involved in invasion of human trophoblast-like choriocarcinoma cell line, BeWo cells -- Hirano et al. 5 (2): 168 ... |
| | Ellis, S.A., Palmer, M.S. and McMichael, A.J. (1990) Human trophoblast and the choriocarcinoma cell line BeWo express a truncated HLA Class I molecule. | | | Taylor, RN., Newman, E.D. and Chen S.A. (1991) Forskolin and methotrexate induce an intermediate trophoblast phenotype in cultured human choriocarcinoma cells. | | | Damsky, C.H., Fitzgerald, M.L. and Fisher, S.J. (1992) Distribution patterns of extracellular matrix components and adhesion receptors are intricately modulated during first trimester cytotrophoblast differentiation along the invasive pathway, in vitro. |
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http://molehr.oupjournals.org/cgi/content/full/5/2/168
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| | Human choriocarcinoma cell line JEG-3 produces and secretes active retinoids from retinol -- Blanchon et al. 8 (5): 485 ... |
| | Tremblay, J., Hardy D.B., Pereira, L.E. and Yang, K. (1999) Retinoic acid stimulates the expression of 11beta-hydroxysteroid dehydrogenase type 2 in human choriocarcinoma JEG-3 cells. | | | Sun, T., Zhao, Y., Mangelsdorf, D.J. and Simpson, E.R. (1998) Characterization of a region upstream of exon I.1 of the human CYP19 (aromatase) gene that mediates regulation by retinoids in human choriocarcinoma cells. | | | Grummer, R., Hellmann, P., Traub, O., Soares, M.J., El-Sabban, M.E. and Winterhager, E. (1996) Regulation of connexin31 gene expression upon retinoic acid treatment in rat choriocarcinoma cells. |
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http://molehr.oupjournals.org/cgi/content/full/8/5/485
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| | National Cancer Institute - Testicular Cancer Treatment |
| | Elevation of the beta subunit of human chorionic gonadotropin (HCG) alone is found in approximately 10% of patients with pure seminoma. | | | A number of prognostic classification schema are in use for metastatic nonseminomatous testicular cancer and for primary extragonadal nonseminomatous germ cell cancers treated with chemotherapy.[ 3 - 5 ] Most incorporate some or all of the following factors which may independently predict worse prognosis: | | | Tumors that appear to have a seminoma histology but that have elevated serum levels of alpha fetoprotein (AFP) should be treated as nonseminomas. |
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http://www.cancer.gov/cancerinfo/pdq/treatment/testicular/healthprofessional
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| | Society for Pediatric Pathology - SPP Publications |
| | These cases support the concept that choriocarcinoma associated with otherwise normal pregnancy arises in the placenta and may be more common than reported. | | | Reluctance to diagnose choriocarcinoma in the presence of chorionic villi can delay diagnosis; however, timely diagnosis of choriocarcinoma is prognostically important, both for the mother and infant. | | | All of the infants survived, and none had evidence of choriocarcinoma. |
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http://path.upmc.edu/spp/pubs/v01-05.htm
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