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| | Cholecystokinin and Anxiety -- Neurotransmitter.net |
 | | We therefore investigated the behavioral and endocrine response of PTSD patients to the panicogen cholecystokinin tetrapeptide (CCK-4). | | | Characterization of the effect of cholecystokinin (CCK) on neurons in the periaqueductal gray of the rat: immunocytochemical and in vivo and in vitro electrophysiological studies. | | | Supraspinal neurotensin-induced antianalgesia in mice is mediated by spinal cholecystokinin. |
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http://www.neurotransmitter.net/cholecystokinin.html
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| | MedlinePlus Drug Information: Cholecystokinin (Diagnostic) |
| | In addition, cholecystokinin increases the movements or contractions of the stomach and intestines. | | | Children—Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of cholecystokinin in children with use in other age groups. | | | The doctor will know if there is anything wrong with these organs if cholecystokinin does not work in the usual way. |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202784.html
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| | On the Measurement of Cholecystokinin -- Liddle 44 (5): 903 -- Clinical Chemistry |
| | Cholecystokinin bioactivity in human plasma: molecular forms, responses to feeding, and relationship to gallbladder contraction. | | | Characterization of the major form of cholecystokinin in human intestine: CCK-58. | | | Izzo RS, Brugge WR, Praissman M. Immunoreactive cholecystokinin in human and rat plasma: correlation of pancreatic secretion in response to CCK. |
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http://www.clinchem.org/cgi/content/full/44/5/903
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| | Cholecystokinin |
| | In addition to its synthesis in small intestinal epithelial cells, cholecystokinin has been clearly demonstrated in neurons within the wall of the intestine and in many areas of the brain. | | | Cholecystokinin plays a key role in facilitating digestion within the small intestine. | | | Cholecystokinin deficiency has been described in humans as part of autoimmune polyglandular syndrome, and was manifest as a malabsorption syndrome clinically similar to pancreatic exocrine insufficiency. |
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http://arbl.cvmbs.colostate.edu/hbooks/pathphys/endocrine/gi/cck.html
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| | Expression of Cannabinoid CB1 Receptors by Vagal Afferent Neurons Is Inhibited by Cholecystokinin -- Burdyga et al. 24 ... |
| | Raybould HE, Gayton RJ, Dockray GJ (1988) Mechanisms of action of peripherally administered cholecystokinin octapeptide on brain stem neurons in the rat. | | | Schwartz GJ, McHugh PR, Moran TH (1993) Gastric loads and cholecystokinin synergistically stimulate rat gastric vagal afferents. | | | Covasa M, Marcuson JK, Ritter RC (2001) Diminished satiation in rats exposed to elevated levels of endogenous or exogenous cholecystokinin. |
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http://www.jneurosci.org/cgi/content/full/24/11/2708
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| | [No title] |
| | A third approach investigates stimulating the body's satiety mechanism. | | | The trypsin inhibitor was postulated to act by inhibiting the negative feedback signal for cholecystokinin secretion. | | | Studies have shown that cholecystokinin is extremely effective in extending satiety following ingestion of a meal. |
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http://www.wipo.int/cgi-pct/guest/getbykey5?KEY=01/17541.010315&ELEMENT_SET=DECL
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| | Molecular characterization and organ distribution of type A and B cholecystokinin receptors in cynomolgus monkey -- ... |
| | Departments of Internal Medicine and Biochemistry/Molecular Biology, Center for Basic Research in Digestive Diseases, Mayo Clinic and Foundation, Rochester, Minnesota 55905 | | | Identification and characterization of various cholecystokinin B receptor mRNA forms in rat brain tissue and partial determination of the cholecystokinin B receptor gene structure. | | | Because the type A cholecystokinin (CCK) receptor is a potentially important target for drug development (2, 11), and |
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http://ajpgi.physiology.org/cgi/content/full/281/2/G507
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| | Mental and Emotional Health: Cholecystokinin in a historical perspective |
| | Mental and Emotional Health: Cholecystokinin in a historical perspective | | | Also, it has been suggested that cholecystokinin might be the neurotransmitter responsible for the satiety signal to the brain. | | | rediscovered cholecystokinin in 1975 as one of the first gastrointestinal peptide found in the mammalian brain. |
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http://www.queendom.com/articles/mentalhealth/pd_cckh.html
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| | Cholecystokinin - definition of Cholecystokinin in Encyclopedia |
| | Cholecystokinin (CCK, previously pancreozymin) is a peptide hormone of the gastrointestinal system responsible for stimulating the digestion of fat and protein. | | | Cholecystokinin thus refers to the movement, or contraction of the gallbladder. | | | Previously, CCK was also called "pancreozymin", referring to its stimulation of the pancreas to release digestive enzymes. |
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http://encyclopedia.laborlawtalk.com/Cholecystokinin
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| | ASAP Dictionary of Anxiety and Panic Disorders |
| | Cholecystokinin (CCK) - a chemical messenger related to some forms of panic disorder and associated with gastrointestinal disorders. | | | CCK-4 is a potent challenge agent that can induce anxiety or panic attacks even in people with no history of anxiety disorder. | | | Challenge Agent - any chemical substance that can produce an anxiety or panic attack. |
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http://anxiety-panic.com/dictionary/en-dictc.htm
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| | Glycated cholecystokinin-8 has an enhanced satiating activity and is protected against enzymatic degradation. - ... |
| | The purpose of the present study was to examine the effects of CCK-8 and glycated CCK-8 on food intake and determine what effect, if any, structural modification of this hormone has on its enzymatic degradation in vitro and biological action in vivo. | | | (5.) Crawley JN, Corwin RL: Biological actions of cholecystokinin. | | | This study demonstrated that CCK-8 is a potent short-term inhibitor of food intake, and that structural modification of this peptide by amino-terminal glycation leads to enhanced satiating activity, partially due to increased resistance to serum aminopeptidase degradation. |
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http://www.highbeam.com/library/doc0.asp?DOCID=1G1:21215664&refid=holomed_1
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| | [No title] |
| | Additional roles of cholecystokinin receptors include the regulation of appetite and metabolism, indicating potential therapeutic applications in the treatment of disorders such as obesity and anorexia nervosa. | | | Cholecystokinin also inhibits gastric emptying and has various effects in the central nervous system, including regulation of appetite and pain. | | | Gastrin and cholecystokinin are key regulators of gastrointestinal function. |
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http://www.wipo.int/cgi-pct/guest/getbykey5?KEY=05/16896.050224&ELEMENT_SET=DECL
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| | NEJM -- Pituitary tumors containing cholecystokinin |
| | The cholecystokinin concentrations were moderately increased in adenomas from another 12 patients, of whom 5 had Cushing's disease and 7 acromegaly with adenomas containing ACTH. | | | We found small amounts of cholecystokinin in the normal human adenohypophysis and therefore examined pituitary tumors from 87 patients with acromegaly, Cushing's disease, Nelson's syndrome, prolactinoma, or inactive pituitary adenomas. | | | We conclude that ACTH-producing pituitary cells may also produce an altered form of cholecystokinin. |
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http://content.nejm.org/cgi/content/abstract/316/20/1244
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| | Cholecystokinin: |
| | The possible role of a brain-gut peptide, cholecystokinin (CCK), in these processes was the initial subject of investigation in this laboratory. | | | Although the physiological regulation of body weight and appetite has been strongly suggested by experimental evidence, the elucidation of the relevant molecular mechanisms has proven difficult. | | | CCK has been extensively evaluated as a possible satiety factor. |
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http://www.rockefeller.edu/labheads/friedman/cholecys.htm
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| | British Journal of Pharmacology - Exogenous cholecystokinin-8 reduces vagal efferent nerve activity in rats through ... |
| | RICHARDS, W.,, HILLSLEY, K.,, EASTWOOD, C. and, GRUNDY, D. (1996) Sensitivity of vagal mucosal afferents to cholecystokinin and its role in afferent signal transduction in the rat.. | | | ZARBIN, M.A.,, WAMSLEY, J.K.,, INNIS, R.B. and, KUHAR, M.J. (1981) Cholecystokinin receptors: presence and axonal flow in the rat vagus nerve.. | | | LEWIS, L.D. and, WILLIAMS, J.A. (1990) Regulation of cholecystokinin secretion by food, hormones, and neural pathways in the rat.. |
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http://www.nature.com/bjp/journal/v129/n8/full/0703270a.html
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| | Cholecystokinin |
| | CCK agonists might have a role in obesity treatment, | | | Isolation of CCK mRNA from a thyroid medullary carcinoma led on to cDNA sequencing followed by characterisation of the CCK gene on chromosome 3 in humans. | | | which was later identified as the above cholecystokinetic and named Cholecystokinin. |
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http://www.guthormones.co.uk/Cholecystokinin.htm
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| | BRAIN NEUROTRANSMITTERS |
| | Cholecystokinin (CCK) seems to function in the production of satiety. | | | Although opioids are generally inhibitory, they have an excitatory effect on hippocampal pyrimidal neurons mediated by inhibition of GABA release. | | | Injection of small quantities of this peptide into the ventricles or the paraventricular nucleus can inhibit feeding. |
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http://www.benbest.com/science/anatmind/anatmd10.html
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| | the GASTROLAB Gastrointestinal Encyclopedia |
| | Under the influence of the hormon cholecystokinin (formed in the duodenum after food intake) the bile is released from the gallbladder into the duodenum. |
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http://www.gastrolab.net/dicteg.htm
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| | Watch what you eat - leptin and cholecystokinin |
| | Watch what you eat - leptin and cholecystokinin | | | Please send any medical news or health news press releases to: | | | Michael Schwartz and colleagues from the University of Washington used rats that develop severe obesity due to genetic absence of leptin receptors. |
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http://www.medicalnewstoday.com/medicalnews.php?newsid=19909&nfid=rssfeeds
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| | Holistic Health Encyclopedia - L |
| | These people will need phenylalanine to help with their depression. | | | Besides producing norepinephrine, dopamine, epinephrine, adrenaline & thyroid, phenylalanine is also a constituent of important brain neuropeptides, somatostatin, vasopressin, melanotropin, ACTH, substance P, encephalin, vasoactive intestinal peptide, angiotensin II, & cholecystokinins. | | | After numerous years of prescribing amino acids, Dr. Slagle has come to first prefer the use of tyrosine over PA for treating depression, low thyroid & stress. |
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http://www.myholistic.com/glossary/L.php3
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| | Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells -- Dabrowski et ... |
| | Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells -- Dabrowski et al. | | | Cholecystokinin and EGF activate a MAPK cascade by different mechanisms in rat pancreatic acinar cells | | | Pertussis Toxin Inhibits Cholecystokinin- and Epidermal Growth Factor-Induced Mitogen-Activated Protein Kinase Activation by Disinhibition of the cAMP Signaling Pathway and Inhibition of c-Raf-1 |
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http://ajpcell.physiology.org/cgi/content/abstract/273/5/C1472
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| | The World's Healthiest Foods: Feeling Great |
| | The movement of chyme through the pyloric sphincter stimulates the intestine to release the hormones secretin and cholecystokinin, which signal the pancreas to release its contents, the pancreatic juice, inside the lumen (the lining) of the duodenum (the first segment of the small intestine). | | | The small intestine, which is specifically designed to maximize the digestion and absorption process, has an expanded surface area with inner folds, called plicae, villi and microvilli, to increase its surface area and enhance its ability to absorb nutrients. |
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http://www.worldshealthiestfoods.com/genpage.php?tname=faq&dbid=16
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| | ASSOCIATION OF CHOLECYSTOKININ-A RECEPTOR GENE POLYMORPHISM WITH ALCOHOL DEPENDENCE IN A JAPANESE POPULATION -- ... |
| | (2000) Gene structure of human cholecystokinin (CCK) type-A receptor: Body fat content is related to CCK type A receptor gene promoter polymorphism. | | | ASSOCIATION OF CHOLECYSTOKININ-A RECEPTOR GENE POLYMORPHISM WITH ALCOHOL DEPENDENCE IN A JAPANESE POPULATION -- Miyasaka et al. | | | Tachikawa, H., Harada, S., Kawanishi, Y., Okubo, T. and Shiraishi, H. (2000) Novel polymorphisms of human cholecystokinin A receptor gene: An association analysis with schizophrenia. |
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http://alcalc.oxfordjournals.org/cgi/content/full/39/1/25
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| | Cholecystokinin |
| | Since its discovery in the brain, anatomical, physiological and pharmacological research on cholecystokinin (CCK) and its possible involvement in neurological and psychiatric disease has continued unabated. | | | In just the last three years, over 1400 papers have been published on CCK. |
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http://www.acnp.org/g4/GN401000056/CH056.html
(6886 words)
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