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Topic: Cholangiocarcinoma



  
 eMedicine - Cholangiocarcinoma : Article by Mahesh Kumar Neelala Anand, MBBS, DNB, FRCR
The incidence of cholangiocarcinomas in patients with ulcerative colitis is 0.4-1.4%, with a latent period of 15 y.)
Cholangiocarcinoma is very responsive to local radiation therapy.
Furthermore, determination of the preferred examination is complex in the presence of a predisposing condition such as primary sclerosing cholangitis (PSC).
http://www.emedicine.com/radio/topic153.htm   (3942 words)

  
 Primary Liver Tumors (cont.)
The only therapy with any chance of curing intrahepatic cholangiocarcinoma is complete surgical removal of the cancer.
Intrahepatic cholangiocarcinoma is an aggressive cancer that has often spread beyond the original location to other sites in the body before the diagnosis is made.
Unfortunately, no studies have demonstrated that chemotherapy and/or radiation therapy extends life in patients with intrahepatic cholangiocarcinoma.
http://www.vicc.org/showcontent.php?id=334   (2616 words)

  
 Cholangiocarcinoma of the Biliary Tract
Decorin staining was not correlated with aggressive behavior of intrahepatic cholangiocarcinoma, whereas intratumoral tenascin staining was correlated with lymphatic permeation and proliferative activity measured by Ki67.
Extrahepatic cholangiocarcinoma remains a dismal disease with only a 22.5% chance of a curative surgical resection, achieving a 5-year survival rate of 44.4%.
MUC2 was rarely expressed in pancreatic ductal carcinoma (1 of 46, 2%) and was negative in the ampullary carcinoma of pancreatobiliary origin and in intrahepatic cholangiocarcinoma.
http://www.thedoctorsdoctor.com/diseases/biliary_cholangioca.htm   (12298 words)

  
 Better Outcomes with Liver Transplant for Hilar Cholangiocarcinoma Patients
Hilar cholangiocarcinoma may be treated by surgical removal of the cancer (resection) in some patients.
For patients with localized, node-negative hilar cholangiocarcinoma, liver transplantation preceded by radiation and chemotherapy may be an alternative to surgical resection, according to a study published in the Annals of Surgery.
Liver transplantation may be an alternative to resection for some patients with hilar cholangiocarcinoma.
http://patient.cancerconsultants.com/news.aspx?id=34970   (603 words)

  
 Thioacetamide-induced intestinal-type cholangiocarcinoma in rat: an animal model recapitulating the multi-stage ...
Praet,M.M. and Roels,H.J. (1984) Histogenesis of cholangiomas and cholangiocarcinomas in thioacetamide fed rats.
Thioacetamide-induced intestinal-type cholangiocarcinoma in rat: an animal model recapitulating the multi-stage progression of human cholangiocarcinoma -- Yeh et al.
Endo,K., Yoon,B.I., Pairojkul,C., Demetris,A.J. and Sirica,A.E. (2002) ERBB-2 overexpression and cyclooxygenase-2 up-regulation in human cholangiocarcinoma and risk conditions.
http://carcin.oxfordjournals.org/cgi/content/full/25/4/631   (2606 words)

  
 MR Imaging of Intrahepatic Cholangiocarcinoma: Use of Ferumoxides for Lesion Localization and Extension -- Braga et al. ...
from needle biopsy or surgery (three patients with cholangiocarcinoma
Advances in surgical techniques have improved the long-term
In our experience, the conspicuity of cholangiocarcinoma on
http://www.ajronline.org/cgi/content/full/177/1/111   (2050 words)

  
 Medical Dictionary: Cholangiocarcinoma - WrongDiagnosis.com
Cholangiocarcinoma (medical condition): Cancer of the digestive bile ducts.
Cholangiocarcinoma: Another name for Bile Duct Cancer (or close medical condition association).
More information on medical condition: Bile Duct Cancer:
http://www.wrongdiagnosis.com/medical/cholangiocarcinoma.htm   (278 words)

  
 Medical Encyclopedia: Cholangiocarcinoma (Print Version)
Primary sclerosing cholangitis, choledochal (bile duct) cysts, and chronic biliary irritation are all associated with increased risk for this condition.
For this condition, see cancer - support group.
Hospice is often a good resource for patients with cholangiocarcinoma that cannot be cured.
http://www.nlm.nih.gov/medlineplus/print/ency/article/000291.htm   (527 words)

  
 p990316a - Cholangiocarcinoma
Complete surgical resection offers the only chance for cure in patients with cholangiocarcinoma.
Question: What are the clinical characteristics and presentations of cholangiocarcinoma?
Jaundice is the presenting symptom in over 90% of patients who present with cholangiocarcinoma.
http://www.emory.edu/WHSCL/grady/amreport/litsrch98/p990316a.html   (252 words)

  
 Inflammatory Cytokines Induce DNA damage and Inhibit DNA repair in Cholangiocarcinoma Cells by a Nitric Oxide-dependent ...
RT-PCR and immunoblot analysis in three human cholangiocarcinoma
Our findings add human cholangiocarcinomas to this group
To more specifically demonstrate iNOS expression in human cholangiocarcinoma
http://cancerres.aacrjournals.org/cgi/content/full/60/1/184   (5420 words)

  
 Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998 -- Taylor-Robinson et ...
Asia and China, development of cholangiocarcinoma is mainly associated
outcomes for cholangiocarcinoma are poor, such studies may lead
Guidelines for the diagnosis and treatment of cholangiocarcinoma: consensus document
http://gut.bmjjournals.com/cgi/content/full/48/6/816   (2819 words)

  
 SSAT - 1997 Abstract: 133 Results of resection for hilar cholangiocarcinoma: American versus Asian experience.
It is very important that you consult a doctor about any specific medical problem or question.
Recently, better results have been reported by our Asian colleagues.
Cholangiocarcinoma involving the hepatic hilum is notorious for locoregional extension and surgical inaccesibility.
http://www.ssat.com/cgi-bin/abstracts/97ddw/ddw133.cgi?affiliation=   (268 words)

  
 Pallimed: A Palliative Medicine Blog: Cholangiocarcinoma review
The last few sections of the review cover palliative therapies** including the role of biliary stenting and photodynamic therapy which I've been reading about for a bit but have yet to see used although, per this reviewer, it sounds quite helpful:
The photodynamic therapy group had higher median survival (493 days
In a prospective study, 39 patients with Bismuth III/IV cholangiocarcinomas were randomised to treatment with either biliary stenting plus photodynamic therapy or stenting alone.
http://pallimed.blogspot.com/2005/10/cholangiocarcinoma-review.html   (609 words)

  
 eMedicine - Cholangiocarcinoma : Article by Peter Darwin, MD
Medicine is a constantly changing science and not all therapies are clearly established.
Absence of biliary ductal dilatation may be misleading in patients with long-standing sclerosing cholangitis.
Most patients with cholangiocarcinoma (CCC) require follow-up care for acute and late adverse effects of therapy.
http://www.emedicine.com/med/topic343.htm   (3295 words)

  
 Cyclooxygenase-2 Promotes Human Cholangiocarcinoma Growth: Evidence for Cyclooxygenase-2-Independent Mechanism in ...
role in the regulation of human intrahepatic cholangiocarcinoma
Western blot analysis showed that celecoxib did not
Cholangiocarcinoma cells were subjected to celecoxib treatment (50 µ
http://cancerres.aacrjournals.org/cgi/content/full/64/4/1369   (5981 words)

  
 Hepatic Pathology
Cholangiocarcinomas do not make bile, but the cells do make mucin, and they can be almost impossible to distinguish from metastatic adenocarcinoma on biopsy or fine needle aspirate.
A liver cancer may have both hepatocellular as well as cholangiolar differentiation.
The carcinoma at the left has a glandular appearance that is most consistent with a cholangiocarcinoma.
http://www-medlib.med.utah.edu/WebPath/LIVEHTML/LIVER032.html   (56 words)

  
 SSAT - 1998 Abstract: EFFECTIVE TOXIN GENE EXPRESSION VIA ADENOVIRAL INFECTION OF HUMAN CHOLANGIOCARCINOMA CELLS IN THE ...
It is very important that you consult a doctor about any specific medical problem or question.
Verification of therapeutic gene transfer to the biliary epithelium in the presence of bile is critical to the clinical application of these gene therapy strategies.
The biliary milieu may present obstacles to clinical gene therapy applications due to ineffective gene transfer in situ.
http://www.ssat.com/cgi-bin/abstracts/98ddw/abstscorrt-137.cgi?affiliation=other   (486 words)

  
 Cholangiocarcinoma - Common Bile Duct
Intrahepatic cholangiocarcinoma with a long-term survival of 12 years after surgical resection: report of a case and review of the literature.
Smith MD; Robbins PD; Cullingford GL; Levitt MD. Cholangiocarcinoma and familial adenomatous polyposis.
Klempnauer J; Ridder GJ; Werner M; Weimann A; Pichlmayr R. What constitutes long-term survival after surgery for hilar cholangiocarcinoma?
http://home.flash.net/~drrad/tf/081197.htm   (373 words)

  
 Tauroursodeoxycholate inhibits human cholangiocarcinoma growth via Ca2+-, PKC-, and MAPK-dependent pathways -- Alpini ...
Consistent with the concept that the Ca pathway regulates cholangiocarcinoma growth by changes in MAPK
TUDCA may be important for the treatment of cholangiocarcinoma.
Cholangiocarcinoma is a liver neoplasm arising from intrahepatic
http://ajpgi.physiology.org/cgi/content/full/286/6/G973   (5890 words)

  
 SIR: Chemoembolisation Effective Treatment Option for Interhepatic Cholangiocarcinoma
PHOENIX, AZ -- March 31, 2004 -- Interhepatic cholangiocarcinoma is a rare cancer that presents a unique clinical challenge, but researchers report encouraging results with a chemoembolisation protocol.
Study title: Interhepatic Cholangiocarcinoma: 10-Year Experience With Treatment With CAM/Ethiodol/PVA Chemoembolization.
SIR: Chemoembolisation Effective Treatment Option for Interhepatic Cholangiocarcinoma
http://www.docguide.com/dg.nsf/PrintPrint/A2DA7FAB8B8248BF85256E68007595FA   (355 words)

  
 Apoptosis and Tumorigenesis in Human Cholangiocarcinoma Cells : Involvement of Fas/APO-1 (CD95) and Calmodulin -- Pan ...
in vitro in Fas-positive human cholangiocarcinoma is 1–5
in our in vitro studies to induce apoptosis of cholangiocarcinoma
not expressed in untreated human cholangiocarcinoma cells cultured in
http://ajp.amjpathol.org/cgi/content/full/155/1/193   (5525 words)

  
 Trail induces cell migration and invasion in apoptosis-resistant cholangiocarcinoma cells -- Ishimura et al. 290 (1): ...
Thus our aim was to examine whether TRAIL is expressed
is a promising agent for cancer therapy; however, many cholangiocarcinoma
pathway in human cholangiocarcinoma cell lines, an observation
http://ajpgi.physiology.org/cgi/content/abstract/290/1/G129   (225 words)

  
 Cyclooxygenase-2-derived Prostaglandin E2 Promotes Human Cholangiocarcinoma Cell Growth and Invasion through EP1 ...
Our findings in this study provide the first evidence for the
patients to the development of cholangiocarcinoma, the molecular
in an animal model of cholangiocarcinoma (8, 9).
http://www.jbc.org/cgi/content/full/280/25/24053   (6008 words)

  
 Re: Cholangiocarcinoma (Bile Duct Cancer) -- VietNow Locator & Message Board
Re: Cholangiocarcinoma (Bile Duct Cancer) -- Donald A. Hamilton, 08:32:28 11/09/05 Wed
I haven't had much luck trying to find anything on in, online.
If there is anything at all that you could share with me, I would really appreciate it.
http://www.voy.com/14001/1785.html   (178 words)

  
 Reversal of Multiple Drug Resistance in Cholangiocarcinoma by the Glutathione S-Transferase-{pi}-Specific Inhibitor ...
GSTP1-1 is a resistance factor for anticancer drugs in cholangiocarcinoma
useful for treatment of cholangiocarcinoma in combination with
Cholangiocarcinoma is a cancer that is highly resistant to various
http://jpet.aspetjournals.org/cgi/content/full/306/3/861   (4822 words)

  
 Cholangiocarcinoma - Wikipedia, the free encyclopedia
Cholangiocarcinoma is an adenocarcinoma of the biliary duct system.
http://en.wikipedia.org/wiki/Cholangiocarcinoma   (101 words)

  
 Recurrent thrombo-embolic episodes: the association of cholangiocarcinoma with antiphospholipid syndrome -- Samadian ...
Recurrent thrombo-embolic episodes: the association of cholangiocarcinoma with antiphospholipid syndrome -- Samadian and Estcourt 75 (879): 45 -- Postgraduate Medical Journal
Recurrent thrombo-embolic episodes: the association of cholangiocarcinoma with antiphospholipid syndrome
The discovery of a cholangiocarcinoma on post mortem leads us to think that the antiphospholipid syndrome could be associated
http://pmj.bmjjournals.com/cgi/content/full/75/879/45   (617 words)

  
 Paraneoplastic Syndromes in Cancer: CASE 3. Parathyroid Hormone-Related Hypercalcemia in Cholangiocarcinoma -- Yen et ...
in our patient was humoral, mediated by the cholangiocarcinoma.
examined, 17.5% had disease due to cholangiocarcinoma without
Parathyroid Hormone-Related Hypercalcemia in Cholangiocarcinoma -- Yen et al.
http://www.jco.org/cgi/content/full/22/11/2244   (888 words)

  
 Transcatheter Arterial Chemoembolization in Unresectable Cholangiocarcinoma: Initial Experience in a Single Institution ...
cholangiocarcinoma were treated with one or more cycles of TACE
Transcatheter Arterial Chemoembolization in Unresectable Cholangiocarcinoma: Initial Experience in a Single Institution
Transcatheter Arterial Chemoembolization in Unresectable Cholangiocarcinoma: Initial Experience in a Single Institution -- Burger et al.
http://www.jvir.org/cgi/content/abstract/16/3/353   (359 words)

  
 HerbChina2000.com - Herbal Remedies - Liver cancer
Cholangiocarcinoma originates in the bile ducts and is often caused by infestation with the liver fluke Clonorchis (a parasite).
The cancer grows along the bile ducts in sheets or lines, and is hard to find on X-ray studies.
Cancer of the bile duct cells is called cholangiocarcinoma.
http://www.herbchina2000.com/therapies/CLC.shtml   (821 words)

  
 News Bureau: MDNews - Mortality rate for intrahepatic cholangiocarcinoma on the rise
Researchers at the Imperial College School of Medicine and other institutions analyzed national morality data for liver, gall bladder, and pancreatic tumors to assess changes in mortality rates for specific tumor types between 1968 and 1998.
In 1993, intrahepatic cholangiocarcinoma surpassed hepatocellular carcinoma as the most commonly recorded cause of death related to liver neoplasms.
In individuals aged 45 years and older, the rate increased 15-fold; in contrast, the rate remained fairly stable in individuals aged 20 to 44.
http://merck.micromedex.com/index.asp?page=newsarchive&news_id=939&news=md   (288 words)

  
 cholangiocarcinoma - definition of cholangiocarcinoma by the Free Online Dictionary, Thesaurus and Encyclopedia.
This information should not be considered complete, up to date, and is not intended to be used in place of a visit, consultation, or advice of a legal, medical, or any other professional.
You may also use the word browser links:
cholangiocarcinoma is not available in the general English dictionary and thesaurus.
http://www.thefreedictionary.com/cholangiocarcinoma   (84 words)

  
 Cholangiocarcinoma
In some countries, there are a lot of cholangiocarcinomas because of liver flukes.
These characteristics can help one recognize mnalignancy regardless of the cell of origin.
http://www.pathguy.com/~tdemark/0009.htm   (60 words)

  
 Bile duct cancer (cholangiocarcinoma) : Cancerbackup
There are approximately 600 new cholangiocarcinomas diagnosed each year in the UK.
The bile ducts are the tubes connecting the liver and gall bladder to the small intestine (small bowel).
http://www.cancerbacup.org.uk/Cancertype/Bileduct/Bileduct   (2994 words)

  
 Medcyclopaedia - Cholangiocarcinoma
See cholangiocarcinoma extrahepatic bile ducts and cholangiocarcinoma intrahepatic bile ducts.
http://www.medcyclopaedia.com/library/topics/volume_iv_1/c/CHOLANGIOCARCINOMA.aspx   (49 words)

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