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| | Why Some Neonates (Newborns) Need Caffeine |
 | | The question of an increase in peripheral chemoreceptor responsiveness (associated or not with a direct, central action of caffeine) remains debatable, particularly in human neonates. | | | This drop in ventilation involves an acute reduction in peripheral chemoreceptor inputs (i.e., physiological chemodenervation) and thus reflects the strength of the peripheral chemoreceptor drive. | | | Peripheral chemoreceptor activity is typically assessed by monitoring the rapid decline in minute ventilation (in the first minute) after inhalation of pure O2. |
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http://www.medicalnewstoday.com/medicalnews.php?newsid=11024
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| | Physiology Department Faculty and Their Research |
| | Chen, J., He, L., Dinger, B. and Fidone, S. Stimulus specific signaling pathways in rabbit carotid body chemoreceptors. | | | His research is focused on the mechanisms of sensory transduction and chemical transmission between preneural receptor cells and afferent nerve terminals in mammalian arterial chemoreceptors, which sense blood levels of O2, H+ and CO2 and reflexly adjust cardiopulmonary parameters. | | | He, L., Dinger, B., Powell, F. and Fidone, S. Evaluation of carotid body chemoreceptor activity elicited by doxapram after a 48 hour hypoxic exposure. |
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http://www-medlib.med.utah.edu/physio/faculty/fidone.html
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| | APStracts 10:0501A, 2003. |
| | Augmented peripheral chemoreceptors have been implicated in early stages of recurrent apneas, congestive heart failure, and certain forms of hypertension. | | | This mini-review summarizes the importance of peripheral chemoreceptor reflexes in various physiological and pathophysiological conditions. | | | In the absence of carotid bodies, compensatory upregulation of aortic bodies as well as other chemoreceptors contributes to the hypoxic ventilatory response. |
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http://www.uth.tmc.edu/apstracts/2003/jap/October/501a.html
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| | EBSDC Component 4 - Open Literature |
| | Relative responses of aortic body and carotid body chemoreceptors to carboxyhemoglobinemia. | | | Comparison of aortic and carotid chemoreceptor responses to hypercapnia and hypoxia. | | | Aortic and carotid chemoreceptor responses to metabolic acidosis in the cat. |
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http://www.health.upenn.edu/ebdc/components/component_4/open/
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| | 2.3 Respiratory Regulation-2 |
| | The peripheral chemoreceptors are the aortic and carotid bodies. | | | is mostly (80%) mediated by the central chemoreceptors but about 20% of the response is due to peripheral chemoreceptor stimulation. | | | The central chemoreceptors are located near the ventral surface of the medulla close to the site of exit of the 9th and 10th cranial nerves. |
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http://www.qldanaesthesia.com/AcidBaseBook/AB2_3B.htm
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| | BRAIN NEUROTRANSMITTERS |
| | Other actions of dopamine include the induction of vomiting by stimulation of D2 cells in the chemoreceptor trigger zone, stimulation of growth hormone release by D2 receptors, and increased exploration and locomotion (thought to be connected to dopaminergic activity in the nucleus accumbens). | | | Acetylcholine was the first neurotransmitter discovered and is the major neurotransmitter in the peripheral nervous system (the only other peripheral neurotransmitter being norepinephrine). | | | Sexual behavior in the male is increased by dopamine agonists, whereas sexual behavior in the female is increased by dopamine antagonists. |
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http://www.benbest.com/science/anatmind/anatmd10.html
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| | Publications |
| | Omental Graft Improves Functional Recovery Of Transected Peripheral Nerve. |
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http://www.mpi-dortmund.mpg.de/publications/searchform.php3
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| | The Pregnancy Institute - PUCP |
| | These changes are simultaneous with cord stimulation and due to chemoreceptor and baroreceptor responses (which are for quick fetal compensation). | | | These patterns form based on late fetal compensation due to acidosis, peripheral vasoconstriction, increases in catacholamines, cortisol and various biochemical defenses. | | | Because it is innervated, it may also send neurologic responses to the brain. |
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http://www.preginst.com/pucp.html
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| | Faculty and Research Interests |
| | I am presently examining the brainstem of male adult rats anesthetized, paralyzed, artificially ventilated, and peripheral chemoreceptor denervated for regions which may be chemosensitive. | | | Thus, prematurity and/or functional deficits in the central chemoreceptor mechanism predisposes to clinical conditions associated SIDS. | | | This research involves an examination of the hypothesis that the chemosensory mechanism might, from a functional point of view, not be fully developed at birth in normal animals and humans. |
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http://www.uta.edu/biology/research/facresearch.htm
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| | Kinesiology Graduate Faculty Research Interests |
| | Peripheral chemoreceptor function following carbonic anhydrase inhibition during moderate intensity exercise. | | | Salmoni has research interests in both gerontology and in ergonomics. | | | (f) applied aspects of motor learning which have dealt with cue utilization in sport and the influence of practice upon peripheral vision in athletes/non-athletes. |
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http://www.uwo.ca/fhs/kinesiology/grad_fac_research.html
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| | Peripheral chemoreceptor |
| | Purves Hypoxia - the Role of the Peripheral Chemoreceptors | | | A peripheral chemoreceptor is a chemoreceptor in the carotid body and aortic body that is stimulated by chemical changes in the composition of the blood. | | | Peripheral Arterial Chemoreceptors and Respiratory-Cardiovascular Integration (Monographs of the Physiological Society, 46) |
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http://www.freeglossary.com/Peripheral_chemoreceptor
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| | Respiratory influence of peripheral chemoreceptor stimulation in maturing rabbits. |
| | Respiratory influence of peripheral chemoreceptor stimulation in maturing rabbits. | | | Both the respiratory depressant effects of hypoxia alone and in combination with NaCN were abolished after denervation of the peripheral chemoreceptors. | | | To evaluate whether the influence of peripheral chemoreceptor (PCR) stimulation is centrally modulated by hypoxia, the respiratory effects of sodium cyanide (NaCN) infusion were compared during room air and 10% O2 inhalation in 18 lightly anesthetized, tracheotomized rabbits of varying postnatal age (1-33 days). |
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http://www.arclab.org/medlineupdates/abstract_3693203.html
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