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| | Ceruloplasmin |
 | | Interaction of neocuproine, 1,10-phenanthroline and 2,2'-dipyridyl with human ceruloplasmin. | | | Induction of ceruloplasmin in rat lung during hyperoxia | | | [Biosynthesis of ceruloplasmin in various rat organs] Puchkova LV; Denezhkina VV; Zakharova ET; Gaitskhoki VS; Neifakh SA Biokhimiia 55: 2095-102 (1990) Ceruloplasmin (CP) biosynthesis in various organs of the rat was studied. |
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http://www.mad-cow.org/~tom/ceruloplasmin.html
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| | Bioline International Official Site (site up-dated regularly) |
| | Middleton RB, Linder MC Synthesis and turnover of ceruloplasmin in rats treated with 17 beta-estradiol. | | | Hormone replacement therapy in postmenopausal women reportedly increased ceruloplasmin concentration. | | | Acute stress was induced before overiectomy, following recovery from surgery, and again after Estradiol Valerate injection (for 10 days) in same group of rats. |
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http://www.bioline.org.br/request?ms04025
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| | Cirrhosis in a Young Woman From Central America -- Answer |
| | A key biochemical difference is that in all other disorders of chronic cholestasis, the ceruloplasmin level is normal or increased, suggesting a defect in biliary copper excretion past the point of entry into the secretory pathway. | | | Perhaps the most useful aspect of nonceruloplasmin copper level is in following its reduction in response to chelation therapy. | | | The level is relatively lower in patients with neurologic or psychiatric disease. |
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http://www.medscape.com/content/2003/00/44/82/448293/ans4.html
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| | INABIS '98 - Aceruloplasminemia |
| | Details of the ligand structure essential for the function of ceruloplasmin have been further provided by the elucidation of the human ceruloplasmin structure by x-ray crystallography (16). | | | The following review will focus on the biology of ceruloplasmin and the human disease - aceruloplasminemia. | | | Further studies of the role of ceruloplasmin in both the systemic and central nervous system iron cycles, elucidating the specific mechanisms of this process, will provide an opportunity to test our hypothesis and may have broader implications for our understanding of the role of iron in human neuropathology. |
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http://www.mcmaster.ca/inabis98/templeton/harris0342/two.html
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| | Nat' Academies Press, Copper in Drinking Water (2000) |
| | Despite careful clinical investigations of afflicted individuals, it is still unclear how ceruloplasmin controls iron homeostasis and tissue distribution. | | | Lack of that form of ceruloplasmin in the aceruloplasminemic patient could also result in neurodegeneration. | | | An increased susceptibility to lipid peroxidation is believed to contribute substantially to the neuropathology, which suggests that free-radical-mediated tissue injury is responsible for the basal-ganglia degeneration (Miyajima et al. |
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http://www.nap.edu/books/0309069394/html/63.html
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| | Dr. Koop - Ceruloplasmin |
| | You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen. | | | The information provided herein should not be used during any medical emergency or for the diagnosis or treatment of any medical condition. | | | This test may be performed when disorders of copper metabolism and/or storage are suspected. |
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http://www.drkoop.com/ency/93/003662.html
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| | Wilson's Disease |
| | The serum ceruloplasmin concentration is routinely available in all clinical laboratories and has a normal range of 20 to 50 mg/dL. | | | It should be noted, however, that 5% of all homozygotes, whether symptomatic or not, and 15% to 50% of WD patients with liver disease, may maintain normal levels of ceruloplasmin. | | | The process of copper incorporation into apoceruloplasmin is also dependent on ATP7B, and this process is absent or diminished in most patients with WD, leading to a reduced circulating level of serum ceruloplasmin in most patients. |
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http://www.clevelandclinicmeded.com/diseasemanagement/gastro/wilsons/wilsons.htm
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| | University of Miami School of Medicine - Glossary - Ceruloplasmin deficiency |
| | Ceruloplasmin deficiency is agenetic condition, also known as aceruloplasminemia. | | | Aceruloplasminemia is inherited as an autosomal recessive condition. | | | Aggressive treatment with deferoxamine, a chelating agent that takes up iron, may halt the progression of these complications. |
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http://www.med.miami.edu/glossary/art.asp?articlekey=16208
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| | Lab News, Sept 1996d, Department of Laboratory Medicine at Yale |
| | Previously, ceruloplasmin was measured in the Chemistry laboratory by a functional assay that relied on the ability of ceruloplasmin to catalyze the oxidation of phenylenediamine. | | | Ceruloplasmin is also elevated in patients who use oral contraceptives. | | | In addition, very low levels of ceruloplasmin are observed in 10-20% of hetero-zygotes as well as some patients with nephrotic syndrome, sprue, and severe hepatic failure, none of whom show the clinical abnormalities of Wilson's disease. |
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http://info.med.yale.edu/labmed/labnews/sept1996d.html
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| | Tissue-specific ceruloplasmin gene expression in the mammary gland. |
| | Ceruloplasmin gene expression in the mammary gland was tissue-specific, with no evidence of expression in brain, heart or other extrahepatic tissues. | | | Ceruloplasmin gene expression was also detected in a human breast adenocarcinoma cell line and in biopsy tissue from women with invasive ductal carcinoma. | | | Biosynthetic studies indicated that the ceruloplasmin mRNA in mammary gland tissue was translated into a 132 kDa protein qualitatively similar to that synthesized in liver. |
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http://www.arclab.org/medlineupdates/abstract_1764031.html
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| | Ceruloplasmin is an interesting molecule |
| | Point is, there can be an ethnic influence on | | | Ceruloplasmin is an interesting molecule, as far as | | | First let me say something about reference ranges |
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http://munstermom.tripod.com/ceruloplasminLD.htm
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| | Ceruloplasmin antibody (ab8749) datasheet |
| | But please do contact us if you would like any reassurance! | | | This antibody reacts with human ceruloplasmin, a 140 kD a globulin of blood plasma. | | | If Ceruloplasmin antibody (ab8749) does not perform as described on this datasheet, notify us within 90 days of delivery using this form, so that we can help you or offer you a replacement or a refund. |
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http://www.abcam.com/?datasheet=8749
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| | Encyclopedia: Ceruloplasmin |
| | Updated 109 days 5 hours 12 minutes ago. | | | Ceruloplasmin (or caeruloplasmin), officially known as ferroxidase or iron(II):oxygen oxidoreductase, is a copper transport protein found in the blood. | | | Image File history File links Gen w/ Deepview from PDB:1KCW File history Legend: (cur) = this is the current file, (del) = delete this old version, (rev) = revert to this old version. |
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http://www.nationmaster.com/encyclopedia/Ceruloplasmin
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| | Toxicity |
| | In the period preceding this investigation the mercury concentrations in workplace air ranged from 0.106 to 0.783 mg/cu m; the range of urinary mercury concentrations was from 0.029 to 0.545 mg/l. | | | Forty one male mercury exposed workers were examined for serum concentration levels of immunoglobulins (IgG, IgA, IgM), alpha-1-antitrypsin (AIAT), alpha-2-macroglobulin (A2M), ceruloplasmin (CPL), and orosomucoid (ORO). |
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http://www.nomercury.org/atsdr.htm
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