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Topic: Cefotetan



  
 RxMed: Pharmaceutical Information - CEFOTAN
Antibiotics, including cefotetan, should be administered with caution to any patient who has demonstrated some form of allergy, particularly to drugs.
Before therapy with cefotetan is instituted, careful inquiry should be made to determine whether the patient has had previous hypersensitivity reactions to cefotetan, cephalosporins, penicillins or other drugs.
http://www.rxmed.com/b.main/b2.pharmaceutical/b2.1.monographs/CPS-%20Monographs/CPS-%20(General%20Monographs-%20C)/CEFOTAN.html

  
 Formulary conversion of cefoxitin usage to cefotetan: experience at a large teaching hospital -- Smith et al. 23 (12): ...
The mean cost of cefotetan therapy was $180.59, which is $130.26 less per patient than a comparable regimen of cefoxitin (mean cost of therapy $310.85).
These patients received either cefotetan therapy or concomitant therapy of an aminoglycoside combined with either clindamycin or mezlocillin.
A total of 960 patients were treated in the first year; no major patterns of ineffectual therapy or adverse events associated with cefotetan usage have emerged.
http://www.theannals.com/cgi/content/abstract/23/12/1024

  
 MedlinePlus Drug Information: Cefotetan Disodium Injection
Your health care provider may tell you to stop your infusion if you have a mechanical problem (such as a blockage in the tubing, needle, or catheter); if you have to stop an infusion, call your health care provider immediately so your therapy can continue.
If you are receiving cefotetan intramuscularly (in your muscle), your health care provider will tell you how to store it properly.
The drug will be either injected into a large muscle (such as your buttock or hip) or added to an intravenous fluid that will drip through a needle or catheter placed in your vein for 30 minutes, one or two times a day.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a686015.html

  
 Virtual Hospital: P & T News
Cefotetan is a cost effective alternative to cefoxitin due to a similar antimicrobial spectrum, favorable pharmacokinetic profile, and lower cost per day of therapy.7 Therefore, cefotetan will replace cefoxitin as the second-generation cephalosporin on the UIHC formulary.
The injectable second generation cephalosporins - cefmetazole, cefotetan, and cefoxitin - have been designated by the Pharmacy and Therapeutics Subcommittee to be therapeutically equivalent and interchangeable.
The Pharmacy and Therapeutics Subcommittee considers cefoxitin and cefotetan to be therapeutically equivalent and interchangeable antibiotics.
http://www.vh.org/adult/provider/pharmacyservices/PTNews/1995/01.95.html

  
 Arch Surg -- Abstract: Hypoprothrombinemia and hemorrhage in a surgical patient treated with cefotetan, April 1991, ...
Hypoprothrombinemia and hemorrhage in a surgical patient treated with cefotetan
Arch Surg -- Abstract: Hypoprothrombinemia and hemorrhage in a surgical patient treated with cefotetan, April 1991, Kaiser et al.
Postoperatively, the patient followed a diet of intravenous nutrition only.
http://archsurg.ama-assn.org/cgi/content/abstract/126/4/524

  
 Cefotetan Disodium
If your condition has not improved within a few days of starting cefotetan disodium, or instead has worsened, tell your doctor.
The decision to stop taking the drug should be made by your doctor.
Cefotetan disodium is generally prescribed for short-term therapy (10 to 14 days).
http://www.wholehealthmd.com/print/view/1,1560,DR_103,00.html

  
 Genesis Health System - Quick Drug Info - Cefotetan (Injection)
If you have severe diarrhea while taking cefotetan, check with your doctor before taking medicine to stop the diarrhea.
Some services or procedures listed here may not be provided by Genesis Health System entities.  Please consult your medical professional for further information.
If your infection does not improve, or if it gets worse, while taking this medicine, talk to your doctor.
http://genesishealth.com/micromedex/quickdrug/dnx0636.aspx

  
 Cephalexin
Bleeding problems, history of (cefamandole, cefoperazone, and cefotetan only)—These medicines may increase the chance of bleeding
When you are taking a cephalosporin, it is especially important that your health care professional know if you are taking any of the following:
Make sure you tell your doctor if you have any other medical problems, especially:
http://www.healthtouch.com/bin/EContent_HT/drugShowLfts.asp?fname=usp0472.htm&title=Cephalexin&cid=L

  
 Absolute bioavailability and noncompartmental analysis of intravenous and intramuscular Cefotan (cefotetan) in normal ...
Absolute bioavailability and noncompartmental analysis of intravenous and intramuscular Cefotan (cefotetan) in normal volunteers -- Zimmerman et al.
Absolute bioavailability and noncompartmental analysis of intravenous and intramuscular Cefotan (cefotetan) in normal volunteers
Cefotetan tautomer was detected in the plasma and urine of all subjects after both routes of administration, but the mean concentrations were only minimal compared to those for cefotetan.
http://www.jclinpharm.org/cgi/content/abstract/29/2/151

  
 Pharmacokinetics and pharmacodynamics of total and unbound cefoxitin and cefotetan in healthy volunteers -- Carver et ...
and cefotetan are needed but our results support the clinical
More studies comparing the clinical outcome of cefoxitin
Cefotetan is a semisynthetic cephalosporin with a broad spectrum of
http://jac.oupjournals.org/cgi/content/abstract/23/1/99

  
 Use of cephalosporins for prophylaxis and therapy of polymicrobial infection in mice -- Brook 37 (7): 1531 -- ...
therapy was delayed, cefotetan and cefmetazole were less effective than
Cefoxitin, cefotetan, and cefmetazole were compared in 10-day therapy of
thetaiotaomicron survived in all abscesses treated with cefotetan and
http://intl-aac.asm.org/cgi/content/abstract/37/7/1531

  
 Cefotetan disodium-induced hemolytic anemia -- Wagner et al. 26 (2): 199 -- The Annals of Pharmacotherapy
To our knowledge, this is the first case of fulminant hemolytic anemia associated with intravenous cefotetan disodium therapy.
Monitoring for hemolysis should be considered for patients who receive multiple courses of therapy.
Positive Coomb's tests have been reported in less than three percent of patients receiving cefotetan.
http://www.theannals.com/cgi/content/abstract/26/2/199

  
 Microbiology Frontline
Also of interest, 36% and 26% of laboratories changed cefotetan and piperacillin-tazobactam interpretations to resistant for potentially ESBL-harboring isolates of E
The data suggest that <50% of laboratories routinely changed ceftriaxone interpretations to resistant for ceftazidime-intermediate or -resistant isolates of E
Table II indicates that this practice was more common among isolates of both bacterial species tested by a Vitek instrument than by a MicroScan instrument.
http://www.microbiologyfrontline.com/archives/vol2_issue1_february02/1_feature.html

  
 Virtual Hospital: Rx Update
The Pharmacy and Therapeutics Subcommittee has determined that the second-generation cephalosporins - cefmetazole, cefotetan, and cefoxitin - are therapeutically equivalent and interchangeable.
The dose of cefotetan must be adjusted downward in renally compromised patients.
This conversion is being made because of the similarity in antimicrobial spectrums of activity, the less frequent dosing requirements of cefotetan, and the lower cost-per-day of therapy with cefotetan.
http://www.vh.org/adult/provider/pharmacyservices/RXUpdate/1995/03.March.95.html

  
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Clinically significant bone loss after intestinal shunt surgery, as in several other clinical situations, results from the combined effects of an unsustained increase in bone resorption and a sustained decrease in bone formation.
Comparisons were made with other drugs (cefoxitin, cefotaxime, piperacillin, rifampicin, clindamycin, tetracycline, chloramphenicol) widely utilized for the treatment of nosocomial infections.
Cefotetan showed the highest activity against all the tested strains, with a geometrical mean of MICs (MG) of 0.32 and a MIC 50 and MIC 90 of 0.12 and 8 micrograms/ml, respectively.
http://darwinpharmacy.com/ref-tetracycline/tetracycline-research-abs3.565.html

  
 Cefotetan Disodium Injection - Drugs & Vitamins - Drug Library - DrugDigest
Check with your health care professional before stopping or starting any of your medicines.
Cefotetan treats many kinds of infections of the skin, bone, stomach, respiratory tract, sinuses, ear, and urinary tract.
Elderly patients are more likely to get serious side effects from cefotetan.
http://www.drugdigest.com/DD/PrintablePages/Monograph/0,7765,1170,00.html

  
 Plasmid-Determined AmpC-Type {beta}-Lactamases -- Philippon et al. 46 (1): 1 -- Antimicrobial Agents and Chemotherapy
or cefotetan, are not affected by commercially available ß-lactamase
and cefotetan) and the clinical introduction of ß-lactamase
A majority of the patients had been treated
http://aac.asm.org/cgi/content/full/46/1/1

  
 WebMD Health - Patient Handout for Cefotetan Disodium Injection
What should I know before taking this medicine?
WebMD Health - Patient Handout for Cefotetan Disodium Injection
A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment.
http://my.webmd.com/drugs/drug-5920-Cefotetan+Disodium+Injection.aspx?...

  
 CEPHALOSPORINS
Used in surgical wound prophylaxis when activity against Bacteroides fragilis is needed.
The cephamycins in some instances (eg: cefotetan) have improved activity against Enterobacteriaceae.
These groups are the "true" second generation cephalosporins (cefamandole, cefuroxime) and the cephamycins (cefoxitin, cefotetan, cefmetazole).
http://www.uic.edu/pharmacy/courses/pmpr342/itokazu/cephalosporins.html

  
 BIAXIN CLARITHROMYCIN CEFOTETAN ► CANADIAN PRICES - Next Day Delivery World Wide
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 [No title]
At this point, we do not have an automatic substitution policy for this product and the coordination of seeking a change in orders has resulted in some delays in surgery.
AstraZeneca has experienced a manufacturing shortage with cefotetan and it is not expected to be released until June.
Please substitute Cefoxitin for Cefotetan during this shortage.
http://www.pathology.washington.edu/academics/residency/Intraweb/Misc/cefotetan.txt

  
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 HighBeam Research: Library Search: Results
Cefotetan and cefoxitin, commonly used to treat endometritis, are...
Perioperative care of the patient with morbid obesity.
Update on the Prevention and Treatment of Sexually Transmitted Diseases.
http://www.highbeam.com/library/search.asp?q=Cefotetan&refid=healthcyclopedia

  
 Pharmacokinetics and tissue penetration of single-dose cefotetan used for antimicrobial prophylaxis in patients ...
Pharmacokinetics and tissue penetration of single-dose cefotetan used for antimicrobial prophylaxis in patients undergoing colorectal surgery
Pharmacokinetics and tissue penetration of single-dose cefotetan used for antimicrobial prophylaxis in patients undergoing colorectal surgery -- Martin et al.
The pharmacokinetics and tissue penetration of cefotetan were studied after
http://aac.asm.org/cgi/content/abstract/36/5/1115

  
 Cefotetan C Drugs and Medications Pharmacy Health English LoCuaL
English : Health : Pharmacy : Drugs and Medications : C : Cefotetan :
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http://locual.com/D/Health/Pharmacy/Drugs_and_Medications/C/Cefotetan

  
 2000 FDA Forum Poster Abstract F06 - Viraraghavan
Direct antiglobulin test was positive in 50 patients (59%), and serologic studies revealed antibodies to cefotetan in 30 patients (35%).
These data suggest that treatment with Cefotetan may induce a potentially severe autoimmune hemolytic anemia.
Cefotetan use and reports of hemolytic anemia have prompted an FDA review of the overall number, severity, and causality of such cases.
http://vm.cfsan.fda.gov/~frf/forum00/f06.htm

  
 Search.com Directory : Health : Pharmacy : Drugs and Medications : C : Cefotetan
Directory Home > Health > Pharmacy > Drugs and Medications > C > Cefotetan
Search.com Directory : Health : Pharmacy : Drugs and Medications : C : Cefotetan
http://www.search.com/dir/Top/Health/Pharmacy/Drugs_and_Medications/C/Cefotetan

  
 Penetration of cefotetan into suction skin blister fluid and tissue homogenates in patients undergoing abdominal ...
Penetration of cefotetan into suction skin blister fluid and tissue homogenates in patients undergoing abdominal surgery
Penetration of cefotetan into suction skin blister fluid and tissue homogenates in patients undergoing abdominal surgery -- Mazzei et al.
The penetration of cefotetan (2-g intravenous bolus) into the suction
http://aac.asm.org/cgi/content/abstract/38/9/2221

  
 Cephalexin Advanced Consumer Drug Information
Cefprozil is also used to treat bronchitis, otitis media, pharyngitis and tonsillitis, sinusitis, and skin and soft tissue infections
They are also used prophylactically to help prevent perioperative infections that may result from colorectal surgery and appendectomies, and in the treatment of penicillin-resistant strains of gonorrhea
Cefotetan has activity similar to that of cefoxitin against B.
http://www.drugs.com/MMX/Cephalexin.html

  
 Dorlands Medical Dictionary
cefotetan disodium, [USP]  the disodium salt of cefotetan, used for the treatment of a wide variety of infections caused by susceptible organisms; administered intravenously or intramuscularly.
http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_c_17zPzhtm

  
 Cefotan (cefotetan) - Cephalosporins - antibiotics used to treat infections caused by bacteria
Apatef is used for the treatment of infections caused by certain bacteria in many different parts of the body, including the abdomen (body trunk), chest and women's reproductive organs.
Any medical information on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a health care professional.
This medicine contains the antibiotic cefotetan which is a member of a group of antibiotics called cephalosporins.
http://www.patienthealthinternational.com/product/2342.aspx

  
 In-vitro study of the susceptibility of cefoxitin/cefotetan resistant Bacteroides fragilis group strains to various ...
that were resistant to both cefoxitin and cefotetan.
http://jac.oupjournals.org/cgi/content/abstract/26/3/353

  
 cefotetan disodium - Resources from the U.S. Government
: Cefotetan disodium-induced hemolytic anemia has been reported previously, and some of these cases have been severe or fatal.
EPA: Federal Register: Table of Contents: :...tetraoxaspiro[5.5]undecane, 33711-33712 Calcium disodium EDTA, 33710-33711 Human drugs: Antibiotic drugs-- Cefotetan and cefotetan disodium injection, 33712.
MedlinePlus Drug Information: Cefotetan Disodium Injection : Cefotetan Disodium Injection.
http://drugs.mongabay.com/resources/cefotetan_disodium.html

  
 Thrombolytic therapy
cephalosporins, such as cefamandole (Mandol), cefoperazone (Cefobid), and Cefotetan (Cefotan)
Also, anyone who has been treated with anistreplase or streptokinase within the past year should tell the physician in charge.
http://www.healthatoz.com/healthatoz/Atoz/ency/thrombolytic_therapy.jsp

  
 Surgical Prophylaxis
Single dose cefotetan versus multiple­dose cefoxitin as prophylaxis in colorectal surgery.
Results of double-blind, placebo-controlled clinical trial of si.ngle dose ceftizoxime vs. multiple dose cefotetan as prophylaxis for patients undergoing vaginal and abdominal hysterectomy.
Combination therapy: 1 gram ceftizoxime IV plus 500 mg metronidazole IV 30-45 minutes before skin incision; second dose if procedure > 3 hours.
http://www.intmed.mcw.edu/drug/SurgProph.html

  
 Cefotetan
Armed Forces Network WebSearch : Health : Pharmacy : Drugs and Medications : C : Cefotetan
http://www.armedforces.net/search/Health/Pharmacy/Drugs_and_Medications/C/Cefotetan/index.shtml

  
 Re: How common is 'drug-induced hemolytic anemia'
The patient received 2 g of intravenous cefotetan intraoperatively and subsequently at 12 and 24 h post-operatively.
During the transfusion of the second unit of PRBC nursing staff observed gross hemoglobinuria and she subsequently developed acute renal failure.
The patient's direct antiglobulin test was reactive and her serum reacted with cefotetan-coated red blood cells (RBCs) and serum plus soluble cefotetan reacted with untreated RBCs.
http://www.madsci.org/posts/archives/aug2000/966753038.Me.r.html

  
 Pharmacy/Drugs and Medications/C/Cefotetan
Home : Pharmacy : Drugs and Medications : C : Cefotetan
http://www.healthboard.com/websites/Pharmacy/Drugs_and_Medications/C/Cefotetan/index.html

  
 Apatef/Cefotan (cefotetan) - treatment of bacterial infections - AstraZeneca
Apatef/Cefotan (cefotetan) is an injectable antibiotic for prophylaxis and treatment of bacterial infections.
Apatef/Cefotan (cefotetan) - treatment of bacterial infections - AstraZeneca
AstraZeneca has marketing rights to Apatef/Cefotan, which is licensed from Yamanouchi International Ltd, in all major countries outside Japan (although it is not available in all markets).
http://www.astrazeneca.com/productbrowse/3_66.aspx

  
 Enlaces : Health : Pharmacy : Drugs_and_Medications : C : Cefotetan :: 100cia.com
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http://www.100cia.com/recursos/enlaces/Health/Pharmacy/Drugs_and_Medications/C/Cefotetan

  
 Cefotetan: a second-generation cephalosporin active against anaerobic bacteria. Committee on Antimicrobial Agents, ...
recommended use of cefotetan to prevent and treat infections against which
of cefotetan, with its attendant costs and risk of development of resistant
AND COSTS: These guidelines should lead to less inappropriate prescribing
http://www.ecmaj.com/cgi/content/abstract/151/5/537

  
 cars - Cefotetan
Cefotetan is an injectable antibiotic of the cephamycin type for prophylaxis and treatment of bacterial infections.
It is a second generation cephalosporin that has some anaerobe converage.
http://www.carluvers.com/cars/Apatef

  
 Excite Deutschland - - Cefotetan > C > Drugs and Medications > Pharmacy > Health (Web-Katalog)
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http://www.excite.de/directory/Top/Health/Pharmacy/Drugs_and_Medications/C/Cefotetan

  
 Cefotetan Stability in Normal Saline and Five Percent Dextrose in Water
During the 31-day study period all solutions stored at 4 degrees Celsius and 23 degrees Celsius lost more than 10% of the initial cefotetan concentration.
A small shift in the UV-spectra of these solutions was also observed during the 31-day study period.
Complete ultra-violet and visible spectra, pH, and physical inspections were also completed on each of the 14 study days.
http://www.icomm.ca/shsc/stab_abs/cefoteta.html

  
 SELECTED THERAPEUTIC GUIDES
Either cefoxitin or cefotetan is preferred for colorectal surgery and appendectomy because these agents have better coverage against bowel anaerobes (including Bacteroides fragilis).
http://www.samford.edu/schools/pharmacy/dic/therap.htm

  
 Infection Rx
Three day course; may resolve spontaneously without therapy.
The gram-negative activity of ampicillin/sulbactam and gentamicin may be less than that of the other combinations listed
Fluconazole has relatively poor activity against these species
http://www.intmed.mcw.edu/drug/InfectionRx.html

  
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 Health - Pharmacy - Drugs and Medications - C - Cefotetan
Health - Pharmacy - Drugs and Medications - C - Cefotetan
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 Cefotan Online, Description, Chemistry, Ingredients - Cefotetan - RxList Monographs
The pH has been adjusted between 4 and 6.5 with sodium bicarbonate and may have been adjusted with hydrochloric acid.
RxList only refers patients to online pharmacies certified by VIPPS, Verified Internet Pharmacy Practice Sites, a program administered by the National Association of Boards of Pharmacy which ensures that member pharmacies offering online prescription services are bona fide, fully licensed, and demonstrate "competent Internet/interstate pharmacy practices."
CEFOTAN in the ADD-Vantage Vial† is intended for intravenous use only after dilution with the appropriate volume of ADD-Vantage diluent solution.
http://www.rxlist.com/cgi/generic2/cefotet.htm

  
 FDA Approvals, Prescribing/Scientific Literature, and Patents for CEFOTETAN
Check with each pharmacy to see if they do business in your country and state.
Cefotan (cefotetan disodium) Injection, AstraZeneca NDA 50-588/S-029 6/20/03 7/6/03 7/8/03 Cefotan (cefotetan disodium) Injection, AstraZeneca NDA 50-588/S-027 Cefotan (cefotetan) Injection, AstraZeneca - For the latest approval information, locate this drug in the e-Pharmacy.
If you do not see the VIPPS seal, contact the pharmacy and ask if they are taking steps to receive the VIPPS certification.
http://www.betterchem.com/DrugFinder/CEFOTETAN/default.htm

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