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| | Cannabinoids and Pain |
 | | Early research also shows that cannabinoids may be effective in treating the painful condition, known as neuropathic pain. | | | Cannabinoids can induce euphoria and a wide variety of behavioral effects, such as changes in attention, deficits in movement and cognitive impairment. | | | The researchers suspect that the cannabinoid blocks pain enhancing molecules that are released after an injury and cuts off a nerve pain signal before it reaches the spinal cord. |
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http://www.unc.edu/gform-links/courses/pre2000fall/psyc070c/cannabinoids.html
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| | Cannabinoids - Wikipedia, the free encyclopedia |
| | All herbal cannabinoids are derived from their respective 2-carboxylic acids (2-COOH) by decarboxylation; that is, catalyzed by heat, light, or alkaline conditions. | | | For the propyl homologues (THCV, CBDV and CBNV), there is a similar pathway that is based on CBGV. | | | Structure Activity Relationships of the Cannabinoids (NIDA Monograph 79 - 1987) |
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http://en.wikipedia.org/wiki/Cannabinoid
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| | Chapter 2 -- CANNABINOIDS AND ANIMAL PHYSIOLOGY |
| | Those changes are mediated by cannabinoid receptors, selective for pain neurons, and unrelated to changes in skin temperature or depth of anesthesia, and they follow the time course of the changes in behavioral responses to painful stimuli, but not the time course of motor changes. | | | Thus, while cannabinoids appear to be conforming to some of the neurobiological effects of other drugs abused by humans, the underlying mechanisms of these actions and their significance in determining the reinforcement and dependence liability of cannabinoids in humans remain undetermined. | | | Cannabinoids are also effective in rodent models of chronic pain. |
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http://mojo.calyx.net/~olsen/MEDICAL/IOM/iom2.html
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| | THC Ministry :: Community :: View topic - Cannabinoids are in every living animal on the planet... |
| | Cannabinoids affect our skin and other parts of our bodies. | | | So what we are seeing is that morphine turns down the Endogenous cannabinoid Arachidonic acid & that seems to be involved in some of the addictive behavior & this is kind of interesting because we know that cannabinoids themselves other than very twisted circumstances do not show addictive behavior. | | | What the cannabinoid system is doing is giving us a way to peacefully & lovingly adapt to change & be open to change. |
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http://www.thc-ministry.net/forum/viewtopic.php?t=17
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| | Cannabinoids destroy cancer |
| | Titled Antineoplastic activity of cannabinoids, this study was funded by the US National Institute of Health, and performed by researchers at the Medical College of Virginia. | | | An article in the October 2003 issue of the medical journal Nature Reviews, explains in detail current research on how cannabinoids can be used to treat cancer and tumors. | | | Despite the promising results, no further research was made, and the study has essentially disappeared from the scientific literature. |
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http://cannabisculture.com/articles/3254.html
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| | eMedicine - CBRNE - Incapacitating Agents, Cannabinoids : Article by Gregory R Bell, MD |
| | This dopaminergic drive elicited by cannabinoids is believed to underlie the reinforcing and addicting properties of marijuana. | | | Among them, THC is the most psychoactive in humans, producing euphoria, relaxation, intensification of ordinary sensory experiences, perceptual alterations, diminished pain, and difficulties with memory and concentration. | | | In 1999, the Institute of Medicine concluded that scientific data support certain therapeutic uses for cannabinoid-based drugs including pain relief, nausea and vomiting, and appetite stimulation. |
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http://www.emedicine.com/emerg/topic921.htm
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| | TSRI - News and Publications |
| | Our research focuses on the mechanism of action of cannabinoids at the cellular level. | | | We use slices of hippocampus obtained from adult rats to study synaptic transmission and potassium conductances in this brain structure. | | | However, studies in our laboratory indicated that eicosanoids augment I |
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http://www.scripps.edu/news/sr/sr98/npgen26.htm
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| | BBC NEWS Health 'Cannabis' brain tumour drug hope |
| | "It is important to note that cannabinoids would need to generate very strong data in the future as there are already a number of VEGF inhibitors in clinical development," he said. | | | The researchers first gave mice cancer resembling the human form of brain cancer they wanted to study. | | | Lead researcher Dr Guzmán said: "As far as we know, this is the first report showing that ceramide depresses VEGF pathway by interfering with VEGF production." |
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http://news.bbc.co.uk/2/hi/health/3561686.stm
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| | Erowid Cannabis Vault : Cannabis Neuroprotective? |
| | Other research has found that anandamide levels in the brains of rats naturally rise after brain injury or death and the cannabinoid system may play a primary role in limiting brain damage. | | | One synthetic cannabinoid, Dexanabinol (HU-211), is already in phase 3 trials (medium scale, involving humans) headed towards governmental approval as a neuroprotective pharmaceutical. | | | Support accessible drug information by Becoming an Erowid Member. |
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http://www.erowid.org/plants/cannabis/cannabis_science1.shtml
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| | Researchers Identify Clues About Marijuana Effects |
| | Rawls' research team is currently investigating the impact of cannabinoids on other physiological systems, such as analgesia and movement, and the brain neurotransmitters that mediate those systems. | | | One such study, "L-NAME, a nitric oxide synthase inhibitor, and WIN 55212-2, a cannabinoid agonist, interact to evoke synergistic hypothermia," published in the February issue of the Journal of Pharmacology and Experimental Therapeutics, reveals how cannabinoids produce one of the drug's most robust actions, hypothermia, or decreased body temperature. | | | "This demonstrates the possibility that NO plays a part in regulating the impact of cannabinoids on body temperature and other cannabinoid-mediated actions," said Rawls. |
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http://www.sciencedaily.com/releases/2004/03/040309071927.htm
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| | Wired News: Another Cannabis Drug Sans Buzz |
| | Paul Mallet, a behavioral pharmacologist researching cannabinoids at Australia's University of New England, is interested in Pharmos' new compounds. | | | Steven Childer of the department of physiology and pharmacology at Wake Forest University is conducting work on cannabinoids in the brain, for example. | | | Mechoulam is a founding father of medicinal marijuana research. |
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http://www.wired.com/news/culture/0,1284,50762,00.html
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| | Cannabinoids in the treatment of symptoms in cancer and AIDS |
| | Established and potential therapeutic applications of cannabinoids in oncology. | | | Cannabinoids in the treatment of symptoms in cancer and AIDS | | | Fast Fact and Concept #093: Cannabinoids in the treatment of symptoms in cancer and AIDS |
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http://www.mywhatever.com/cifwriter/library/eperc/fastfact/ff93.html
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| | ICRS -The International Cannabinoid Research Society |
| | The ICRS is dedicated to research in all fields of the cannabinoids, ranging from biochemical, chemical and physiological studies of the endogenous cannabinoid system to studies of the abuse potential of recreational cannabis. | | | In addition to acting as a source for impartial information on cannabis and the cannabinoids, the main role of the ICRS is to provide a forum for researchers to meet and discuss their results. | | | Our aim for this webpage is to provide information to members of the society on forthcoming events, as well as to provide an interactive forum for discussion of methodologies and results. |
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http://cannabinoidsociety.org
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| | Cannabinoids |
| | There are about 60 related cannabinoids in cannabis — at least 2 others (cannaninol and cannabidiol) have psychoactive effects |
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http://www.uni.edu/walsh/cannabis.html
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| | DEA Briefs & Background, Drugs and Drug Abuse, Drug Descriptions, Cannabis |
| | One of these, delta-9-tetrahydrocannabinol (THC), is believed to be responsible for most of the characteristic psychoactive effects of cannabis. | | | In the United States, cannabis is legitimately grown only for scientific research. | | | Among the cannabinoids synthesized by the plant are cannabinol, cannabidiol, cannabinolidic acids, cannabigerol, cannabichromene, and several isomers of tetrahydrocannabinol. |
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http://www.usdoj.gov/dea/concern/cannabis.html
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