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Topic: Buprenorphine



  
 Buprenorphine - Wikipedia, the free encyclopedia
Buprenorphine and methadone are both used for short-term and long-term opioid maintenance therapy.
The practice of using buprenorphine (Subutex or Suboxone) in an inpatient rehabilitation setting is increasing rapidly.
A clinical trial conducted at Harvard Medical School in the mid-1990s, demonstrated that a majority of unipolar non-psychotic patients with major depression refractory to conventional thymoleptic antidepressants could be successfully treated with buprenorphine (Bodkin JA, et al., 1995).
http://en.wikipedia.org/wiki/Buprenorphine   (1845 words)

  
 Suboxone: What Is Suboxone, Buprenorphine, Subutex, Oxycontin detox, buprenorphine, Alcohol Detox
Buprenorphine was originally used for pain control when it was available as an injectable drug in the U.S. It has been used as a detoxification medication in Europe since the mid-1980’s where it had been available in a tablet form.
Buprenorphine can be used as a detoxification drug to get you drug free.
Like methadone, buprenorphine can be used for maintenance; however in my practice the goal of treatment is to become drug free.
http://www.nabumed.com/pages?page_id=BAPUI43550   (823 words)

  
 NGC - NGC Summary
In patients being treated with buprenorphine for opioid addiction, it is important to screen for and manage common comorbid medical conditions and to anticipate known and potential drug interactions.
Patients maintained on buprenorphine whose acute pain is not relieved by nonopioid medications should receive the usual aggressive pain management, which may include the use of short-acting opioid pain relievers.
Intensive buprenorphine monitoring activities are required, and treating physicians may be called upon to verify and explain treatment regimens (e.g., to parole and probation officers); to document patient compliance; and to interact with the legal system, employers, and others.
http://www.guideline.gov/summary/summary.aspx?view_id=1&doc_id=5887   (2685 words)

  
 Intelligence Bulletin: Buprenorphine: Potential for Abuse
Buprenorphine is the only opiate addiction therapy drug that can be prescribed in a physician's office; others must be dispensed in a clinic.
Subutex (buprenorphine hydrochloride) is used in the initial stages of therapy while Suboxone (buprenorphine hydrochloride and naloxone hydrochloride) is used in the maintenance stage.
However, buprenorphine can provide opiate addiction therapy to individuals addicted to lower doses of opiates, to those in rural areas with inadequate access to treatment, and to those in areas where methadone clinics have reached full capacity.
http://www.usdoj.gov/ndic/pubs10/10123   (2056 words)

  
 Buprenorphine-About Buprenorphine Therapy
The induction phase is the medically monitored startup of buprenorphine therapy.
This section provides a brief overview of the clinical use of buprenorphine (Suboxone® and Subutex®) for opioid addiction therapy.
There are three phases of buprenorphine maintenance therapy: induction, stabilization, and maintenance.
http://buprenorphine.samhsa.gov/about.html   (1393 words)

  
 News: About Buprenorphine
Buprenorphine is a medical intervention which is most effective when integrated within a substance abuse treatment program, including professional therapeutic interventions and peer support activities.
Buprenorphine is a medication for treating addiction to opiates like heroin, OxyContin and other pain killers.
This adds Buprenorphine to the tool kit of medications – including methadone, providers can utilize to facilitate a positive treatment experience, and help
http://www.tarzanatc.org/News/news_buprenorphine.php   (564 words)

  
 The Buprenorphine FAQ - Version 2.01 WIP
Buprenorphine, exactly like methadone, is a medication given to keep people off of heroin and improve their, and society in general's, quality of life.
Buprenorphine's major clinical importance is as an agonist.
Buprenorphine: a review of its pharmacological properties and therapeutic efficacy.
http://www.geocities.com/nephalim1327/Bupe-FAQ-201-WIP.htm   (8753 words)

  
 Bi-Valley Medical Clinic, Inc. - Buprenorphine
Counseling is a critical and mandatory component of the success of this treatment and involves individual sessions with a psychiatric nurse and/or counselor.
Each program or doctor is allowed to treat up to thirty patients with buprenorphine.
The duration of the taper process is individualized and will be determined by the patient and our medical and counseling staff.
http://www.bi-valley.com/Pages/Buprenorphine.htm   (1186 words)

  
 Buprenorphine Treatment Option
However, NIDA officials are quick to caution that approval of buprenorphine would not diminish the importance of methadone in the treatment of heroin addiction.
These limited side effects can be attributed to the fact that buprenorphine is a partial mu agonist, explains Dr. Eric Strain, a researcher in the Behavioral Pharmacology Research Unit at the Johns Hopkins University School of Medicine in Baltimore.
As a partial mu agonist, buprenorphine has some potential for misuse, making it subject to diversion--being sold by patients to other addicts.
http://www.nida.nih.gov/NIDA_Notes/NNVol10N1/Bupren.html   (1348 words)

  
 Congress OKs Prescription Buprenorphine
Proponents of mixing buprenorphine with naxolone say that it is necessary to ensure that users don't misuse buprenorphine or take illegal drugs while they're receiving their treatment.
Others feel that prescription buprenorphine is a first step to getting Congress to approve legislation that would allow doctors to prescribe any anti-addiction drug to their patients, including methadone.
While buprenorphine has proven successful in helping casual users or mild addicts in forgoing their habits, it has not yet proven successful in treating many heavily-dependent addicts.
http://www.november.org/razorwire/rzold/20/20034.html   (586 words)

  
 buprenorphine and naloxone - [Medication]
Buprenorphine and naloxone may dangerously increase the effects of other drugs that cause drowsiness, including antidepressants, alcohol, antihistamines, sedatives (used to treat insomnia), other pain relievers, anxiety medicines, and muscle relaxants.
Your doctor may want to perform blood tests or other forms of monitoring during treatment with buprenorphine and naloxone.
Tell your doctor about all medicines that you are taking, and do not take any other prescription or over-the-counter medicine, including herbal products, without first talking to your doctor.
http://www.peacehealth.org/kbase/multum/d04819a1.htm   (1865 words)

  
 Buprenorphine as a detoxification medication; 42 references with abstracts - doctordeluca.com
Buprenorphine may be a valuable alternative to clonidine, dextropropoxiphene and methadone in the detoxification of opiate addicts
After neutralization, buprenorphine analyzed by RIA was in the range of 0.01 to 0.47 ng/mg.
The results of this clinical trial indicated that buprenorphine was acceptable to patients and as effective as methadone in the detoxification treatment of heroin addicts
http://www.doctordeluca.com/Library/References/BupDtx2.htm   (9213 words)

  
 Buprenorphine
This training is designed for physicians who are likely to treat opiate-dependent persons in their practice, such as those in family practice, general internal medicine, psychiatry, pediatrics and adolescent medicine specialists.
AAAP buprenorphine training sessions meet the requirements specified in the Drug Addiction Treatment Act of 2000.
AAAP is one of five organizations designated by the U.S. Department of Health and Human Services (DHHS) to provide such training for physicians to dispense buprenorphine in office practice for treatment of opioid dependence.
http://www.aaap.org/buprenorphine/buprenorphine.html   (328 words)

  
 Buprenorphine
Designed for addiction counselors, this 3-hour course, Buprenorphine Treatment of Opioid Addiction—A Counselor's Guide, prepares counselors as they guide patients and their families on the use of buprenorphine in office-based and other healthcare and substance abuse treatment settings.
SAMHSA announces the availability of Treatment Improvement Protocol (TIP) 40, the first clinical practice consensus guide produced by leading experts on the use of buprenorphine for the treatment of patients addicted or dependent on heroin or prescription pain medications, such as oxycodone, hydrocodone or meperidine.
If you are looking for doctors in your area who can prescribe buprenorphine for opioid addiction click here for the SAMHSA Buprenorphine Physician Locator.
http://buprenorphine.samhsa.gov   (904 words)

  
 Clinical Research - Buprenorphine Studies
FRANCE: Report on buprenorphine and methadone in practice
The other report from the 'Liberation' is of a rural study under way in Alsace normalising drug treatments to community doctors and pharmacies.
There are numerous anecdotes of previous heroin addicts getting on with their lives while on substitution treatment, mostly buprenorphine.
http://www.opiateaddictionrx.info/addiction/bupstudy.html   (372 words)

  
 MedlinePlus Drug Information: Buprenorphine Sublingual and Buprenorphine and Naloxone Sublingual
Buprenorphine (Subutex) and buprenorphine and naloxone (Suboxone) are used to treat opioid dependence (addiction to opioid drugs, including heroin and narcotic painkillers).
This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.
tell your doctor and pharmacist if you are allergic to buprenorphine, naloxone, or any other medications.
http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a605002.html   (970 words)

  
 Schedule of Controlled Substances: Proposed Rule: Rescheduling of Buprenorphine From Schedule V to Schedule III
Both foreign data on buprenorphine and the U.S. experience with other drugs like buprenorphine have been viewed by both the DHHS and the DEA as significant and relevant to the control of buprenorphine under the CSA.
Buprenorphine products have been diverted from legitimate channels through theft, doctor shopping and fraudulent prescriptions.
Since the original review conducted by the FDA in the early 1980s (prior to the marketing of Buprenex), a substantial amount of human experience with buprenorphine products as well as a number of scientific studies have provided new information.
http://www.deadiversion.usdoj.gov/fed_regs/rules/2002/fr0321.htm   (2693 words)

  
 Subnanogram-concentration measurement of buprenorphine in human plasma by electron-capture capillary gas ...
Buprenorphine effects on human heroin self-administration: an operant analysis.
A trial of sublingual buprenorphine in cancer pain.
A clinical trial of buprenorphine: comparison with methadone in the detoxification of heroin addicts.
http://www.clinchem.org/cgi/content/full/43/12/2292   (5067 words)

  
 Buprenorphine Update
The safety and effectiveness profiles for buprenorphine and buprenorphine/naloxone suggest they could be dispensed under controlled circumstances that would be delineated in the product labeling and associated rules and regulations.
The treatment of patients by physicians or group practice would allow office-based treatment to augment the current system, while placing an adequate level of control on the dispensing of these medications.
Of that group, fully half maintained that they did not want treatment in the current narcotic treatment program system.
http://www.psychosocial.com/addiction/bupren.html   (1341 words)

  
 National Poll of Physicians Finds Barriers to Widespread Buprenorphine Use
Eight percent of respondents had exclusively treated patients with Subutex® (buprenorphine only); 35% had only prescribed Suboxone® (buprenorphine/naloxone in combination); and 23% had prescribed both.
In October, 2002, the prescription drug manufacturer Reckitt Benckiser received approval from the Food and Drug Administration to market Subutex® and Suboxone®, buprenorphine and buprenorphine/naloxone products used to treat addiction to opiates such as heroin or prescription analgesics.
We were interested in finding out directly from authorized physicians what barriers, if any, are preventing further use and what have been their overall impressions and experiences.
http://www.jointogether.org/sa/news/features/reader/0,1854,567169,00.html   (1054 words)

  
 Amazon.com: Buprenorphine Therapy of Opiate Addiction (Forensic Science and Medicine): Books: Albert D. Fraser,Pascal ...
Covers all aspects of buprenorphine therapy to treat the heroin addicted.
Details the latest analytical advances in drug testing for buprenorphines and describes current prescription and monitoring practices in France and Australia.
http://www.amazon.com/exec/obidos/tg/detail/-/158829031X?v=glance   (549 words)

  
 Erowid Buprenorphine (Temgesic, Subutex) Vault
Buprenorphine Proves Effective Treatment for Heroin Addiction, NIDA Notes
It is an analgesic (pain killer) and has gained a great deal of notoriety for its ability to interrupt severe opiate addiction, including heroin and methadone addictions.
New drug treats the new face of addiction - USA Today, Jan 24 2006
http://www.erowid.org/pharms/buprenorphine/buprenorphine.shtml   (125 words)

  
 The Buprenorphine Initiative
Establishing teams composed of a physician, nurse, physician assistant, counselor and patient advocate to both coordinate and make decisions about buprenorphine integration at their clinic; 2.
Provide physician education and training on addiction treatment, integrated services, and the use of buprenorphine; 2.
As a demonstration project, this initiative seeks to determine the feasibility and/or effectiveness of integrating buprenorphine opioid abuse treatment into HIV primary care settings.
http://hab.hrsa.gov/special/\SPNS05RPT\bup.htm   (2827 words)

  
 ASAM - Buprenorphine Home Page 2003
Columbia, MD Buprenorphine and Office Based Treatment of Opioid Dependence
Madison, WI Buprenorphine and Office Based Treatment of Opioid Dependence
Augusta, ME Buprenorphine and Office Based Treatment of Opioid Dependence
http://www.asam.org/conf/Buprenorphineconferences.htm   (202 words)

  
 MedlinePlus Drug Information: Narcotic Analgesics For Surgery and Obstetrics (Systemic)
Buprenorphine or similar medicines—The narcotic analgesics may not work if you are taking buprenorphine or other similar medicines
Central nervous system (CNS) depressants (medicine that causes drowsiness)—The CNS depressant and other effects of either these medicines or the narcotic analgesics may be increased
http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/202391.html   (1174 words)

  
 Buprenorphine Info
This is an initial clinical contract between the patient and provider of buprenorphine treatment, listing what adherence to treatment is necessary to remain at the office-based level of care.
This is the text of the law allowing office-based use of narcotics to treat addiction: the Drug Addiction Treatment Act of 2000.
It focuses on the drug use history, and on needle-related illnesses.
http://www.asam.org/info/buprenorphine_info.htm   (467 words)

  
 DEA Briefs & Background, Drugs and Drug Abuse, Drug Descriptions, Buprenorphine
DEA Briefs and Background, Drugs and Drug Abuse, Drug Descriptions, Buprenorphine
This drug is a semi-synthetic narcotic derived from thebaine and is currently being investigated for the treatment of narcotic addiction.
Unlike the other treatment drugs, buprenorphine produces far less respiratory depression and is thought to be safer in overdose.
http://www.usdoj.gov/dea/concern/buprenorphine.html   (108 words)

  
 Outpatient Buprenorphine Opiate Detoxification
If you have any questions regarding buprenorphine in the detoxification from Oxycontin, Percocet, Vicodin, Methadone, Heroin or other narcotic drugs, this is THE place to share your experience, strength and hope with others who are on the road of recovery.
I was one of the original researchers on buprenorphine in 1987 when it was first discovered that buprenorphine helped in withdrawal from opiates.
The website www.nabumed.com contains information on my own detox program as well as an "addictionary" of drugs and their effects.
http://groups.msn.com/OutpatientBuprenorphineOpiateDetoxification   (181 words)

  
 Drug Policy Alliance: Opioid Treatment Programs Can Now Offer Buprenorphine
Join the Drug Policy Alliance's work to promote drug policies based on science, compassion, health, and human rights.
Buprenorphine is an opiate used for the treatment of opiate dependence.
Subutex, which contains only buprenorphine, is intended for use at the beginning of treatment.
http://www.drugpolicy.org/news/05_28_03opioid.cfm   (253 words)

  
 SAMHSA Buprenorphine Clinical Discussion WebBoard
If you would like to locate the doctors in your area who prescribe buprenorphine for the treatment of opioid addiction, please visit the SAMHSA Buprenorphine Physician Locator Web site at
The SAMHSA Buprenorphine Clinical Discussion WebBoard is a moderated password-protected Web site in which physicians holding waivers from SAMHSA under the authority of the Drug Addiction Treatment Act of 2000 (DATA) can ask and answer clinical questions regarding the use of buprenorphine for the treatment of opioid addiction.
For more information about the SAMHSA Buprenorphine Clinical Discussion WebBoard, e-mail us at info@buprenorphine.samhsa.gov, or call 866-BUP-CSAT (866-287-2728).
http://bup-webboard.samhsa.gov/login.asp   (222 words)

  
 Publications on Buprenorphine
12, No. 2): SAMHSA Helps Bring Buprenorphine to the Field
TIP 40: Clinical Guidelines for the Use of Buprenorphine in the Treatment of Opioid Addiction
Quick Guide for Physicians Based on TIP 40: Clinical Guidelines for the Use of Buprenorphine in the Treatment of Opioid Addiction
http://store.health.org/catalog/results.aspx?h=drugs&topic=245   (176 words)

  
 Suboxone info, Buprenorphine info, Subutex, Suboxone (buprenorphine/naloxone) info - What's the difference?
Buprenorphine / Naloxone Suboxone and Subutex Treatment for Opiate addiction
Subutex is used little in the U.S. Some physicians may use it in the very beginning of treatment, or if the patient has a reaction to naloxone.
Buprenorphine is a generic name for a chemical compound and is short for Buprenorphine Hydrochloride and is a semi-synthetic opioid.
http://www.helpmegetoffdrugs.com/wst_page2.html   (129 words)

  
 Buprenorphine definition - Medical Dictionary definitions of popular medical terms
Buprenorphine: A prescription medication for people addicted to heroin or other opiates that acts by relieving the symptoms of opiate withdrawal such as agitation, nausea and insomnia.
The side effects of buprenorphine include cold or flu-like symptoms, headaches, sweating, sleeping difficulties, nausea, and mood swings.
Subutex is intended for use at the beginning of treatment while Suboxone is intended for the maintenance treatment of opiate addiction.
http://www.medterms.com/script/main/art.asp?articlekey=38304   (262 words)

  
 Clinical Trial: Effects of Buprenorphine/Naloxone in Treating Opioid Dependent Individuals Who Are Maintained on ...
Buprenorphine is a drug that may be helpful in treating opioid dependent individuals who were previously maintained on methadone.
Buprenorphine is a mixed agonist-antagonist opioid that is being developed as a treatment for opioid dependence.
The purpose of this study is to determine the effects of different doses of buprenorphine/naloxone in treating opioid dependent individuals who were previously maintained on methadone.
http://www.clinicaltrials.gov/ct/gui/show/NCT00000243   (286 words)

  
 The National Alliance of Advocates for Buprenorphine Treatment
Serve as a conduit connecting patients in need of treatment to qualified treatment providers.
Help reduce the stigma and discrimination associated with patients with addiction disorders.
Educate the public about the disease of opioid addiction and the buprenorphine treatment option.
http://www.naabt.org   (88 words)

  
 Buprenorphine
This drug may cause mild anorexia and slight hyperactivity in rodents.
Due to delayed onset of action, buprenorphine should be administered at least 20 minutes prior to the completion of a surgical procedure.
Multiple doses of buprenorphine in rats has occasionally been associated with a tendency of the rats to ingest bedding and subsequently exhibit decreased appetite for food.
http://campusvet.wsu.edu/infofac/buprenorphineuse.htm   (548 words)

  
 SAMHSA-CSAT-DPT:buprenorphine
Using Buprenorphine for Office-Based Treatment of Opiate Addiction
The Center for Substance Abuse Treatment (CSAT) has developed this website to assist States, the medical community, and the addiction community as they begin to implement the use of buprenorphine for opioid addiction treatment.
Buprenorphine Listserve: Part of this initiative includes a listserve.
http://dpt.samhsa.gov/buprenorphine.htm   (206 words)

  
 Methadone, buprenorphine, drug treatment at Recovery Month
The Physician Locator is an on-line resource designed to assist the States, medical and addiction treatment communities, potential patients, and/or their families in finding information on locating physicians who can prescribe buprenorphine (Suboxone® and Subutex®) for treatment of opioid addiction.
CSAT's Division of Pharmacologic Therapies (DPT) manages the day-to-day regulatory oversight activities necessary to implement new SAMHSA regulations (42 CFR Part 8) on the use of Opioid agonist medications (methadone and LAAM) approved by the Food and Drug Administration (FDA) for addiction treatment.
On October 8, 2002 the Schedule III narcotic medications Subutex® (buprenorphine hydrochloride) and Suboxone® tablets (buprenorphine hydrochloride and naloxone hydrochloride) received FDA approval for the treatment of opioid addiction.
http://www.recoverymonth.gov/2005/medtreat   (143 words)

  
 Wired 13.04: The Bitter Pill
For all these reasons, doctors and mental health professionals expected bupe to take off quickly.
But bureaucrats, doctors, and much of the treatment industry are just saying no. A case study in why the best technology doesn't always win.
Buprenorphine could end heroin addiction, curb disease, and cut crime.
http://www.wired.com/wired/archive/13.04/bupe.html   (1030 words)

  
 Meditox of Palm Beach
The Palm Beach Method was adapted specifically for high functioning, motivated people who need individual attention and guidance so they can free themselves from chemical addictions while continuing with their lives.
Its philosophy draws upon recent breakthroughs in science and technology which have given rise to the discovery of medications (i.e., Buprenorphine) designed for the safe and comfortable withdrawal from opiate dependency.
Meditox of Palm Beach (or the Palm Beach Method) is a new protocol for outpatient opiate detoxification.
http://www.meditoxofpalmbeach.com/method.aspx   (193 words)

  
 Subutex and Suboxone Information Page
Subutex (buprenorphine hydrochloride) and Suboxone tablets (buprenorphine hydrochloride and naloxone hydrochloride) is approved for the treatment of opiate dependence.
Subutex (buprenorphine hydrochloride) and Suboxone tablets (buprenorphine hydrochloride and naloxone hydrochloride)
http://www.fda.gov/cder/drug/infopage/subutex_suboxone   (46 words)

  
 Buprenex Online, Description, Chemistry, Ingredients - Buprenorphine - RxList Monographs
Buprenex (buprenorphine hydrochloride) is a narcotic under the Controlled Substances Act due to its chemical derivation from thebaine.
Each ml of Buprenex contains 0.324 mg buprenorphine hydrochloride (equivalent to 0.3 mg buprenorphine), 50 mg anhydrous dextrose, water for injection and HCl to adjust pH.
Buprenorphine hydrochloride is a white powder, weakly acidic and with limited solubility in water.
http://www.rxlist.com/cgi/generic2/buprenorphine.htm   (125 words)

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