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| | Filariasis - Wikipedia, the free encyclopedia |
 | | Wuchereria bancrofti can affect the legs, arms, vulva, breasts, while Brugia timori rarely affects the genitals. | | | Filariasis is a parasitic and infectious tropical disease, caused by the thread-like parasitic filarial worms, Wuchereria bancrofti, Brugia malayi, and Brugia timori, all transmitted by mosquitoes. |
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http://en.wikipedia.org/wiki/Filariasis
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| | eMedicine - Filariasis : Article by Michael D Nissen, BMedSc, MBBS, FRACP, FRCPA |
| | The consequence is lymphatic damage and chronic leakage of protein-rich lymph in the tissues, thickening and verrucous changes of the skin, and chronic streptococcal and fungal infections, which all contribute to the appearance of elephantiasis. | | | B malayi elephantiasis is more likely to affect the upper and lower limbs, with genital pathology and chyluria being rare. | | | Chyluria also may be present in chronically infected persons. |
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http://www.emedicine.com/med/topic794.htm
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| | Brugia malayi |
| | The aim is to "represent a non-redundant view of all B. | | | The Brugia malayi Gene Index (BmGI) from The Institute of Genomic Research (TIGR) integrates research data from international EST sequencing and gene research projects. | | | malayi genes and data on their expression patterns, cellular roles, functions, and evolutionary relationships". |
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http://bioresearch.ac.uk/browse/mesh/D017178.html
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| | Resources - |
| | Library construction was supported by a sub-contract from a grant (NIH/NIAID U01-AI50903-02) awarded to Dr. Elodie Ghedin at The Institute for Genomic Research (TIGR). | | | The CHORI-106 (BAC) library has been constructed by Chung-Li Shu and Kazutoyo Osoegawa in Pieter de Jong's laboratory, BACPAC Resources, Children's Hospital Oakland Research Institute. | | | Data on the CHORI-106 clone average insert size has been determined by Pulsed Field Gel Electrophoresis. |
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http://bacpac.chori.org/brugia106.htm
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| | Brugia malayi chitinase (BmCHT1), Human Parasite Drug Targets, New England Biolabs |
| | Brugia malayi chitinase (BmCHT1) is expressed in the microfilarial stage, the first larval stage, of the organism and is thought to be important in the exsheathment process of the microfilaria (1). | | | The microfiliaria of Brugia malayi have been shown to have chitin in their sheaths (3). | | | Brugia malayi chitinase (BmCHT1), Human Parasite Drug Targets, New England Biolabs |
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http://www.neb.com/nebecomm/products/productP5205.asp
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| | Filariases: Strategic Research - Gene Discovery |
| | malayi - these may be useful in the search for new targets for the development of drugs, vaccines or diagnostic tests; | | | malayi - these may be important in developing new ways to block the development of the parasite. | | | Researchers are currently using this method to look for genes from B. malayi and other nematodes that influence the host’s immune response and play a role in protective immunity. |
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http://www.who.int/tdr/research/progress/fil_str/discovery.htm
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| | Brugia malayi |
| | Brugia malayi: The causative agent of Brugian lymphatic filariasis of humans | | | The symptoms of Brugian filariasis begin earlier than those of Bancroftian filariasis, often within a month or less. | | | The nocturnally periodic form is found in areas with rice fields and the nocturnally subperiodic form is found in rural villages and plantations along the lower reaches of major rivers in swamp forests (see HERE for some comments on periodicity). |
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http://maven.smith.edu/~sawlab/fgn/pnb/brugmal.html
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| | Brugi malayi (elephantiasis) |
| | Many aspects of the biology of Brugia malayi are similar to Wuchereria bancrofti. | | | The primary difference between the two species is that brugian filariasis is not as widely distributed as is bancroftian filariais, although the distributions of the two diseases overlap in many areas of the world (view geographic distribution of filariasis). | | | It is a vector borne disease, spread by mosquitos (view diagram of the life cycle), and it can cause elephatiasis. |
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http://www.biosci.ohio-state.edu/~parasite/brugia.html
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| | AllRefer.com - elephantiasis (Pathology) - Encyclopedia |
| | In tropical countries the most common cause is filariasis, infestation with certain filaria, small parasitic roundworms (see worm) of the genera Wuchereria bancrofti or Brugia malayi that are introduced into the body by many species of mosquitoes. | | | The adult worms live in the lymphatic system, causing local inflammation, fibrosis, and obstruction, and resulting in the characteristic enlargement and thickening of the skin. |
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http://reference.allrefer.com/encyclopedia/E/elphntia.html
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| | Rajan lab |
| | We focus our efforts on understanding the biology of human lymphatic filariasis, using Brugia malayi as a model and various deficient mice as hosts. | | | malayi requires a leukotriene to complete its development. | | | We have also been examining the factors determining host immunity against this parasite. |
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http://cmp.uchc.edu/Rajan_lab/rajan_lab.htm
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| | Filariasis |
| | The two species of worms most often associated with this disease are Wuchereria bancrofti and Brugia malayi. | | | The larval form of the parasite transmits the disease to humans by the bite of a mosquito. | | | Filariasis is an infectious tropical disease caused by any one of several thread-like parasitic round worms. |
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http://my.webmd.com/hw/health_guide_atoz/nord116.asp
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| | B1 B Lymphocytes Play a Critical Role in Host Protection against Lymphatic Filarial Parasites -- Paciorkowski et al. ... |
| | Rajan, T.V., Shultz, L.D, Yates, J., Greiner, D.L. B lymphocytes are not required for murine resistance to the human filarial parasite, Brugia malayi. | | | Brugia malayi and Brugia pahangi third stage (L3) larvae were | | | Ash, L., Riley, J. Development of subperiodic Brugia malayi in the jird, Meriones unguiculatus, with notes on infections in other rodents. |
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http://www.jem.org/cgi/content/full/191/4/731
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| | Edinburgh Research Archive : Item 1842/171 |
| | Because B. malayi is known to secrete homologs (Bm macrophage migration inhibitory factor (MIF)-1 and -2) of the human cytokine MIF, we chose to investigate the role this cytokine mimic may play in the development of the novel macrophage phenotype observed during infection. | | | A Brugia malayi Homolog of Macrophage Migration Inhibitory Factor Reveals an Important Link Between Macrophages and Eosinophil Recruitment During Nematode Infection | | | Infections with the helminth parasite Brugia malayi share many key features with Th2-mediated allergic diseases, including recruitment of eosinophils. |
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http://hdl.handle.net/1842/171
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| | Filariases: Strategic Research - Vaccine candidates |
| | For both antigens, the region of the molecule responsible for generating the protective immune response has been identified. | | | Present on the surface of Brugia malayi microfilariae (larval worms), this enzyme is crucial for the parasite’s development. | | | Present in multiple worm stages of Brugia malayi, vaccination in animal models induces partial protection to both microfilariae and adult worms. |
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http://www.who.int/tdr/research/progress/fil_str/vaccine.htm
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| | Brugia Database |
| | TEXT SEARCH to identify Brugia consensus sequences that show similarity to genbank entries or that contain prosite motifs. | | | ID QUERY using Brugia Consensus ID numbers or genbank identifiers for specific EST sequences. | | | The Brugia malayi Database contains consensus sequences generated from aligning the Brugia malayi sequences contained in dbEST as of September 18, 1998. |
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http://www.cbil.upenn.edu/ParaDBs/Brugia_2
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| | Brugia malayi Genome Project |
| | Funding for this project is being provided by the National Institute of Allergy and Infectious Diseases (NIAID) | | | Listed right below is a collection of information on Brugia malayi genome research at TIGR. | | | Annotated sequences will be displayed based on their map position and will be searchable by clone name as well as by gene name. |
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http://www.tigr.org/tdb/e2k1/bma1
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| | Energy Citations Database (ECD) - Energy and Energy-Related Bibliographic Citations |
| | Availability information may be found in the Availability, Publisher, Research Organization, Resource Relation and/or Author (affiliation information) fields and/or via the "Full-text Availability" link. | | | For a journal article, please see the Resource Relation field. | | | Brugia malayi: vaccination of jirds with /sup 60/cobalt-attenuated infective stage larvae protects against homologous challenge |
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http://www.osti.gov/energycitations/product.biblio.jsp?osti_id=5650665
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| | Nematode Net |
| | Worms, which are spread by mosquitos, reside in the human lymphatic system where they can block lymphatic drainage. | | | The complete genomic sequence for B. malayi is in progress at The Institute of Genomic Research (TIGR), funding by NIH-NIAID. | | | Filarial worms infect over 100 million people in tropic regions (Wucheria bancrofti is more common than Brugia malayi). |
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http://www.nematode.net/Species.Summaries/Brugia.malayi/index.php
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| | Blaxter Lab |
| | Using gridded BAC libraries, we are generating genome maps for Brugia malayi | | | Filarial nematodes live in symbiosis with a bacterial partner, closely related to the Wolbachia parasites of arthropods. | | | Brugia malayi genome sequence from Edinburgh and the Sanger Institute |
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http://nema.cap.ed.ac.uk/fgp.html
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| | The Sanger Institute: Brugia malayi |
| | This project involves end sequencing of over 4600 BACs and producing 150kb of finished sequence of the region around the MIF-1 locus, which is covered by 7 BAC sequences that have been mapped by the Blaxter Lab. | | | The Sanger Institute is carrying out a combined sequencing and mapping project of Brugia malayi in collaboration with Mark Blaxter at The University of Edinburgh. | | | All sequences produced at The Sanger Institute can be downloaded from the Sanger Institute FTP site. |
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http://www.sanger.ac.uk/Projects/B_malayi
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| | Untitled Document |
| | In 1927, Lichtenstein and Brug identified microfilaria that were distinct from the previously discovered Wucheria bancrofti while in Indonesia. | | | The adults were isolated in 1977 by Partono and named Brugia timori. | | | Human Biology 103 Parasites and Pestilence Spring 2004 Instructor: D. |
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http://www.stanford.edu/class/humbio103/ParaSites2004/Filariasis/history.htm
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| | Wolbachia Genome Project |
| | (2005) The Wolbachia Genome of Brugia malayi: Endosymbiont Evolution within a Human Pathogenic Nematode. | | | and Integrated Genomics, Inc. (IG) have completed the DNA sequence and preliminary annotation of the genome of Wolbachia from Brugia malayi. | | | The work has been published in PLOS Biology [Foster J, Ganatra M, Kamal I, Ware J, Makarova K, et al. |
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http://tools.neb.com/wolbachia
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| | B74.1 Filariasis due to Brugia malayi - OneLook Dictionary Search |
| | You can look up the words in the phrase individually using these links: b74.1 | | | You might try using the wildcards * and ? | | | If you're sure it's a word, try doing a general web search for B74.1 Filariasis due to Brugia malayi: Google, AltaVista |
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http://www.onelook.com/?w=B74.1+Filariasis+due+to+Brugia+malayi&ls=all
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| | [No title] |
| | SOURCE Wolbachia endosymbiont strain TRS of Brugia malayi ORGANISM Wolbachia endosymbiont strain TRS of Brugia malayi Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales; Rickettsiaceae; Wolbachieae; Wolbachia. | | | REFERENCE 1 (bases 1 to 1080084) AUTHORS Foster,J., Ganatra,M., Kamal,I., Warel,J., Makarova,K., Ivanova,N., Bhattacharyya,A., Kapatra,V., Kumar,S., Posfail,J., Vinczel,T., Ingram,J., Moran,L., Lapidus,A., Omelchenko,M., Krypides,N., Ghedin,E., Wang,S., Goltsman,E., Joukov,V., Ostrovskaya,O., Tsukerman,K., Mazur,M., Comb,D., Koonin,E. and Slatko,B. TITLE The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode JOURNAL PLoS Biol. | | | LOCUS NC_006833 1080084 bp DNA circular BCT 05-FEB-2005 DEFINITION Wolbachia endosymbiont strain TRS of Brugia malayi, complete genome. |
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http://tools.neb.com/wolbachia/data/NC_006833.gb
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| | Brugia spp. - Material Safety Data Sheets (MSDS) |
| | malayi transmitted by various species of Mansonia, Anopheles and Aedes; B. timori transmitted by Anopheles barbirostris | | | INCUBATION PERIOD: Variable; allergic manifestations may appear as early as a month after infection; microfilariae may not appear in blood until 3-6 months after infection. | | | SYNONYM OR CROSS REFERENCE: Brugia malayi, B. timori, filariasis, Brugian filariasis, Malayan filariasis, Timorean filariasis |
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http://www.phac-aspc.gc.ca/msds-ftss/msds24e.html
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| | The Sanger Institute: Brugia malayi |
| | You can find out about all the Brugia Malayi EST sequences generated at the sanger here | | | The number at the end of the filename will refer to the release date of that file (day_month_year). |
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http://www.sanger.ac.uk/Projects/B_malayi/ftp.shtml
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| | Filariasis |
| | (Lymphatic Filariasis, Elephantiasis, Lymphedema, Wuchereria bancrofti Infection, Brugia malayi Infection, Brugia timori Infection, Loa loa Infection) | | | Click on the graphic below to vote for this page as a Starting Point Hot Site. |
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http://www.medconsumer.info/topics/filariasis.htm
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| | Brugia Blast Server |
| | Enter the e-mail address to which you requre the results to be sent | | | Select which BLAST executable you wish to use | | | For further info on the Brugia ESTs contact Mark Blaxter (mark.blaxter@ed.ac.uk) |
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http://www.dbbm.fiocruz.br/genome/parasite-genome/Brugia_blast_server.html
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| | NCBI Nematode Genome Resources |
| | Genome sequence of Brugia malayi: The first genome of a parasitic nematode has been published (Ghedin et al., 2004). | | | The C. elegans RefSeq collection was updated to represent data submitted from WormBase (WS144). |
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http://www4.ncbi.nlm.nih.gov/genome/guide/nematode
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| | Brugia malayi ESTs |
| | The project bioinformatics strand is dedicated to performing quality analyses on the EST dataset: these are made available through downloadable or www-accessible databases. | | | Searching the Brugia malayi EST dataset in NEMBASE |
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http://nema.cap.ed.ac.uk/fgn/ests.html
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