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Topic: Bone healing



  
 How an electrical bone growth stimulator for spinal fusion works
Electrical bone growth stimulators are a supplemental form of therapy to help enhance the body’s bone healing process … a process that is absolutely essential for the success of any type of spinal fusion surgery.
During surgery, the surgeon lays down bone fragments (usually taken from iliac crest in the patient’s hip) in the segment of the spine to be fused.
The fusion of these bone fragments stops the motion in the affected segment of the spine, and thereby eliminates or reduces the pain that was created by the motion.
http://www.spine-health.com/topics/surg/stimulator/stim01.html   (572 words)

  
 Do NSAIDs inhibit bone healing?
The purpose of this document is to examine the evidence for effects of NSAIDs on bone healing.
Smoking is also a potent inhibitor of repair of bone injury, and of normal bone function, and is likely to be an important confounder in studies of the effects of NSAIDs and coxibs on bone.
Interference in bone healing, especially union after spinal fusion surgery, has already been seen in one analysis, and has been explored further in another [24] that retrospectively identified 357 patients who underwent a posterior instrumented fusion at either L4-L5 or L4-S1.
http://www.jr2.ox.ac.uk/bandolier/booth/painpag/wisdom/NSAIbone.html   (3936 words)

  
 BONE GRAFT ALTERNATIVES
Bone grafts that are transplanted directly from one area of an individual’s skeleton into his or her own spine are called autogenous bone grafts, or bone autografts.
Bone grafts can also be used in surgical procedures to stabilize the spine after a fracture or to correct deformity.
Once the bone “bridge” between the vertebrae is in place, the spine is stabilized and movement and pressure on nerve roots is relieved, thus easing pain.
http://www.spine.org/articles/bone_grafts.cfm   (1316 words)

  
 Online Orthopaedics - Electrical Stimulation of Bone Healing
Electrical stimulation of the bone healing is a very old technique and has been studied for at least 25 years.
Frequently, when a bone does not heal, a medically prescribed bone healing system can be used to promote healthy bone growth and repair when normal bone healing has not appeared to be satisfactory.
Just as the patient is unaware of the electrical current produced by their own body, they are not aware of the electrical current produced by the bone healing system.
http://www.orthopodsurgeon.com/elecstim.html   (1073 words)

  
 Mechanical Effects on Fracture Healing
This agrees with bone adaptation theories because osteogenesis and modeling are physiologic pathways for mechanically mediate bone adaptation which have a much greater potential to change tissue structure.
In this section we will first review biological processes of fracture healing, discuss how these healing processes determine mechanical behavior of healing bone, discuss theories of how external mechanical stimulus can affect healing bone, and finally, discuss how these theories of healing and mechanical stimulus affect clinical fracture fixation treatments.
The third classification of bone alteration is osteogenesis, the ability to change bone structure when laying bone down on soft tissues, either fibrous soft tissue or cartilage.
http://www.engin.umich.edu/class/bme456/bonefracture/bonefracture.htm   (3051 words)

  
 Bone Healing Studies
Their clearly documented resistance to the usual forms of surgical treatment, including bone grafting, served as a reasonable control in judging the efficacy of this new therapeutic method, particularly when PEMFs were the sole change in patient management.
This enhancement of the femoral bone formation of the ischemic rat model by the static magnetic field seems to be due to the improved blood circulation of the femur.
For this long-term follow-up study, all patients who had healed in the original study were recalled for a follow-up radiograph.
http://www.therionresearch.com/database/bone_healing.html   (8508 words)

  
 [No title]
Healing of bone as influenced by rigid immobilization
In such instances healing process is probably little different from that which occurs using external fixation alone.
Allograft: Bone is transferred between genitically dissimilar members of the same species.
http://www.cmki.org/LMHS/Chapters/5b-BoneHealing.htm   (2766 words)

  
 All About Back & Neck Pain: Articles
The most common use of bone graft is to stimulate the healing of bone.
Bone grafting is used for many types of orthopedic procedures that require bones to heal.
If the bone is taken from the person's own body, there may also be osteocytes (living bone cells) that survive being transferred to the new location and continue to do their work of making new bone.
http://www.allaboutbackandneckpain.com/html/spinesub.asp?id=17   (849 words)

  
 UCLA Engineering: News Center
By studying diseases in which the human body generates too much bone, UCLA researchers have discovered and isolated a natural molecule that can be used to heal fractures and generate new bone growth in patients who lack it.
The problem with taking a patient’s own bone for this procedure is that aside from the pain, which often becomes severe and persistent, there is a high risk of infection.
Another current option is to use the patient’s own bone grafted from another part of the body.
http://www.engineer.ucla.edu/news/2005/bones.html   (956 words)

  
 BBC NEWS Health Painkillers 'prevent bone healing'
A US study found that when rats were given non-steroidal anti-inflammatory drugs (NSAIDs), their broken bones healed more slowly that normal, or never fully healed.
None of the rats given rofecoxib were able to heal their bones.
Dr Patrick O'Connor, from the University of New Jersey, who led the research, said: "Ibuprofen and indomethacin delay bone healing by about one to two weeks in rats, which is the equivalent to slowing it down by 25 to 50% in humans," says O'Connor.
http://news.bbc.co.uk/1/hi/health/2026619.stm   (506 words)

  
 Enhancement of bone defect healing in old rats by TGF-beta and IGF-1.
The ability to induce bone healing in aging by TGF-beta+IGF-1 is of a great clinical importance for restoration of bone strength and biomechanical properties of bone defects in aging.
The ability of growth factors to enhance bone formation in femoral defects in old rats was tested.
Biomechanical tests indicated that treatment with TGF-beta, IGF-1 or TGF-beta+IGF-1 resulted in a significant increase of bone bending rigidity compared to control in the 4 weeks group and that TGF-beta+IGF-1 was the most inductive in this respect.
http://www.arclab.org/medlineupdates/abstract_11830358.html   (278 words)

  
 Smoking -- Can It Affect Bone Healing?
The researchers studied 29 patients who were being treated for a fractured tibia (shin bone) and who developed infection of the bone (osteomyelitis).
Now, there is also some evidence that bone heals slower in smokers than in nonsmokers.
One researcher at the University of California in San Francisco thinks nicotine may cause bone and soft tissue to heal slower in smoking patients.
http://www.hughston.com/hha/a.smoke.htm   (468 words)

  
 Kick nicotine for faster bone healing?
While the link between smoking and bone harm is clear, no one knows why it occurs, says Dr. Thomas Einhorn, chairman of orthopedic surgery at Boston University.
It will take a few years of additional animal research before that theory can be tested in smokers, he says, although there's no down side to people trying to kick the habit in hopes it will help heal their bones.
Now, armed with a new $1.4 million grant from the Defense Department, Zuscik is out to prove that theory, and whether going cold-turkey for a short time after breaking a bone or undergoing bone surgery might help smokers heal faster.
http://www.dailysouthtown.com/southtown/dsnews/189nd2.htm   (741 words)

  
 USATODAY.com - Some pain killers may delay bone healing
But some bone experts call the research compelling enough that doctors should explain the risk before patients choose a painkiller for a broken bone, spinal surgery or other bone injury.
New research suggests some of the most widely used painkillers may delay healing of a broken bone — and one study, albeit in animals, that's getting lots of doctors' attention suggests the blockbuster sellers Vioxx and Celebrex are among the culprits.
Indomethacin-treated rats took a week longer to heal than untreated rats; the resulting bone was as strong.
http://www.usatoday.com/news/health/2002-05-28-bone-healing.htm   (702 words)

  
 MedlinePlus Medical Encyclopedia: Bone fracture repair
Bone grafts may be used to allow for proper healing or to speed the healing process.
The advantage of surgery is that it often allows early mobility and faster healing than nonsurgical treatment.
Children's bones heal rapidly, usually in 6 weeks.
http://www.nlm.nih.gov/medlineplus/ency/article/002966.htm   (598 words)

  
 Pain Killers May Delay Bone Healing
Indomethacin-treated rats took a week longer to heal than untreated rats; the resulting bone was as strong.
ccording to the AP story, bone experts call the research compelling enough that doctors should explain the risk before patients choose a painkiller for a broken bone, spinal surgery or other bone injury.
From the May 28, 2002 Associated Press comes a report of new research that suggests some of the most widely used painkillers may delay healing of a broken bone.
http://www.chiropracticresearch.org/News_pain_killers_may_delay_bone_heal.htm   (232 words)

  
 UCSF Researchers Identify Key Genes In Bone Healing Process That Could Lead To New, Molecular-Based Treatments
This type of targeted, molecular-based treatment would be more desirable than a bone graft, which currently is the most common therapy for a problem fracture, according to Miclau.
A graft involves taking bone from elsewhere in the body, usually the pelvis, and carries an overall complication rate of about 25 percent.
Now we can use these principles to begin to develop new clinical treatments for troublesome fractures in which we mimic the natural healing process," said Theodore Miclau, MD, lead investigator and UCSF assistant professor of orthopaedic surgery who treats patients at San Francisco General Hospital Medical Center.
http://www.eurekalert.org/pub_releases/1999-02/UoCS-URIK-050299.php   (534 words)

  
 [No title]
The osteoinductive capacity of a BMP is expected to allow it to be used clinically to enhance regeneration of bone in cases that would normally require bone grafting.
Improved treatment methods may not only replace bone graft, but may also speed bone healing.
Various bone grafting materials are used with different degrees of success.
http://www.orl.med.umich.edu/orl/clin/c14.htm   (553 words)

  
 chondrotin supports healthy joints
Animal studies indicate that chondroitin sulfate may promote healing of bone, which is consistent with the fact that the majority of glycosaminoglycans found in bone consist of chondroitin sulfate.
The effect of chondroitin sulfate on bone healing.
Chondroitin Sulfate - For Bone Healing, Joint Health, and Osteoarthritis
http://www.bodyandfitness.com/Information/Health/Research/chondrotin.htm   (822 words)

  
 NONSTEROIDALS DELAY BONE HEALING?
Continued use of nonsteroidals delays bone healing (8), and taken over several months, they can increase the rate of cartilaginous breakdown in joints of people who have osteoarthritis (9,10,11).
They block prostaglandins that cause pain, but are also the first step in healing, so several papers show that what you gain in pain control, you may lose in actually delaying healing (6,7).
Effect of nonsteroidal antiinflammatory drugs on fracture healing: A laboratory study in rats.
http://www.drmirkin.com/joints/7788.html   (494 words)

  
 Military funds research on how nicotine impairs bone healing
Slower healing means a greater chance of re-injury and can lead to chronic pain and disability.
One goal of the research then is to determine, based on biochemical evidence, the window of time during which healing has the greatest chance of being delayed by cigarette smoke.
Long-term health concerns aside, military experts say smoking reduces soldiers' readiness to fight by impairing night vision, weakening the immune system and lengthening healing time.
http://www.medicalnewstoday.com/medicalnews.php?newsid=32238   (803 words)

  
 British Medical Journal: Effects of NSAIDs on bone healing have been widely reported in maxillofacial journals - Letter ...
These various studies randomised patients to placebo or non-steroidal anti-inflammatory drug; they did not specifically study bone healing, but the authors would have been obliged to report any adverse effects and they did not report any delay in bone healing.
Varghese et al's work on rodents should not be extrapolated to the clinical situation and seems to be of only academic or veterinary interest.[5] Not only would a trial be unnecessary but it would also be of questionable ethics if it deprived patients of these valuable and effective drugs.
Maxillofacial journals have published an abundance of reports studying the effects of various non-steroidal anti-inflammatory drugs on pain relief after the surgical removal of third molars[2-4] The healing dental socket replicates the biology of fracture healing.
http://www.findarticles.com/p/articles/mi_m0999/is_7191_318/ai_54654570   (385 words)

  
 [No title]
Nonsteroidal anti-inflammatory painkillers known as NSAIDs continue to be prescribed for patients as part of their recovery for healing fractures even though using these medications have been found to diminish bone healing, formation and remodeling.
In some cases, however, some NSAIDs have a positive effect on soft-tissue healing by stimulating collagen that can increase the strength in the early phases of skin and ligament healing, but results have been inconclusive.
As a result, researchers believe NSAIDs exert significant effects on the slowing of bone formation after injuries, the healing of fractures and the growth of bone around prostheses.
http://mercola.com/2004/jun/30/painkillers_bones.htm   (503 words)

  
 Bone Growth Stimulation Devices*
The effect of low-intensity pulsed ultrasound therapy on time to fracture healing: a meta-analysis.
Invasive or noninvasive electric bone growth stimulators may be considered medically necessary as an adjunct to spinal fusion surgery for patients with any of the following high risks for failed spinal fusion:
Noninvasive electrical bone growth stimulators may be considered medically necessary for both of the following conditions: 
http://www.wellmark.com/e_business/provider/medical_policies/policies/Fracture_Healing_Devices.htm   (930 words)

  
 ASA 149th Meeting Lay Language Papers -The healing of bone - a new field for shock waves?
But recent studies showed that even lower energy levels, which did not show any destructions of the bone, were able to enhance bone healing.
This leads us to continue our research in this field because the extracorporal shock wave therapy would be a noninvasive method with low complication rate to heal pathologic bone conditions with body's own substances.
It also concerns all fields of non-union of bones, in which physicians must come up with.
http://www.aip.org/149th/hausdorf.html   (565 words)

  
 UNMC to participate in clinical trial using adult stems cells to enhance bone healing
Aastrom’s TRCs are also being used in a clinical trial in Spain for jaw bone reconstruction preparatory to maxillary sinus lift procedures, to generate sufficient jaw bone for successful dental implants.
In this trial, five of six patients treated with TRCs exhibited clinical and functional healing as determined by radiographic imaging within six months.
About 90 percent of the time, the bone particles will graft with the existing bone and healing will occur.”
http://app1.unmc.edu/publicaffairs/newsarchive/view_art.cfm?article_id=1163   (574 words)

  
 Researchers Show COX-2 Inhibitors Interfere With Bone Growth, Healing
While acknowledging the limitations of animal research, Goodman said this study "has great applicability to humans, because the healing process is virtually the same" for rabbit and human bones.
UCSF Study Shows Novel "Stress-Sharing" Prosthetic Device To Save Legs With Cancer Stimulates Bone Development (April 16, 1999) -- A clinical study led by UC San Francisco researchers has found that a new prosthetic device primarily used to save legs with cancer stimulates bone development.
The study, conducted in rabbits, also suggests that physicians should consider changing prescribing patterns since many doctors commonly prescribe anti-inflammatory drugs including COX-2 inhibitors under the very circumstances in which the drugs should be avoided.
http://www.sciencedaily.com/releases/2002/11/021120064725.htm   (955 words)

  
 A Role for Advanced Glycation End Products in Diminished Bone Healing in Type 1 Diabetes -- Santana et al. 52 (6): 1502 ...
that the degree of healing of circular osteotomies was reduced
Further studies in nondiabetic animals indicated that bone healing
on bone healing used circular craniotomy defects of 1.0-, 1.6-,
http://diabetes.diabetesjournals.org/cgi/content/full/52/6/1502   (5201 words)

  
 EBI - Products
Healing may occur earlier when the EBI Bone Healing System
EBI is the original developer and leading provider of bone growth stimulators
is the most widely studied bone growth stimulator
http://www.ebimedical.com/products/detail.cfm?p=0C   (201 words)

  
 Bone Healing - compare prices, reviews and buy at NexTag - Price - Review
Calcium with Magnesium and Zinc is necessary for proper bone development, muscle function, reproduction, immune response, nervous system health, blood pressure, wound healing, and...
Can also be used beore after surgery to promote healing time.
Health & longevity through the healing power of nature - that's what it means to Trust the Leaf.
http://www.nextag.com/serv/main/buyer/OutPDir.jsp?search=bone+healing   (253 words)

  
 Spiritual Healing: Encyclopedia Of Natural Healing
I thought, how do I choose the best option for encyclopedia of natural healing?
spiritual healing - natural healing - music healing - tarot - phone psychic
You decide what encyclopedia of natural healing is right for you.
http://www.spiritual-healing-4u.com/2005/03/encyclopedia-of-natural-healing.php   (105 words)

  
 Bone healing - definition of Bone healing in Encyclopedia
Necrotic bone is then demolished by osteoclasts, and the haematoma by macrophages.
This is where all of the cells that participate in the healing of bone originate.
After a fracture, the first thing that forms is a haematoma, similar to that seen elsewhere in the body.
http://encyclopedia.laborlawtalk.com/Bone_healing   (247 words)

  
 Products that enhance fracture healing and bone repair
-BSM, Bone Substitute Material, is a purely synthetic bone graft substitute that resorbs and is replaced with bone during the healing process.
Products that enhance fracture healing and bone repair
ETEX Corporation specializes in the development of calcium phosphate-based bone graft substitutes, implant surface coatings, and resorbable orthopedic devices.
http://www.etexcorp.com   (72 words)

  
 Impairment of Bone Healing by Insulin Receptor Substrate-1 Deficiency -- Shimoaka et al. 279 (15): 15314 -- Journal of ...
Impairment of Bone Healing by Insulin Receptor Substrate-1 Deficiency -- Shimoaka et al.
http://www.jbc.org/cgi/reprint/279/15/15314   (21 words)

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