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| | From the Grand Rounds Archive at Baylor |
 | | The bleeding time is an in vivo assessment of platelet response to limited vascular injury and is reflective of the integrity of the primary hemostatic mechanism. | | | Because surgery is a thorough challenge to the hemostatic system, any history of excessive bleeding with prior surgical procedures may indicate a bleeding disorder. | | | This material should not be used as a basis for treatment decisions, and is not a substitute for professional consultation and/or peer-reviewed medical literature. |
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http://www.bcm.edu/oto/grand/11394.html
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| | SVMB: Bleeding Time Unaffected by Addition of Cilostazol to Aspirin or Clopidogrel in Peripheral Arterial Disease ... |
| | They scrutinised relationships between their baseline bleeding and platelet characteristics and how the patients responded to therapy with aspirin, clopidogrel and cilostazol alone and in various combinations. | | | In Dr. Wilhite's study, none of the patients who received the triple combination developed bleeding problems, and Dr. Jaff said he has not encountered any such bleeding episodes among his patients. | | | While aspirin and clopidogrel appeared to increase bleeding times and influenced platelet aggregation in vitro, the addition of cilostazol did not significantly change those figures, Dr. Wilhite said. |
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http://www.pslgroup.com/dg/234A3A.htm
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| | Method for determining bleeding time - Patent 5031619 |
| | During the period of external bleeding, temperature compensation member 13 senses localized temperature of the subject. | | | The temperature sensitive material is removably positioned on the subject's skin in a working area. | | | The compensation member 13 is removably positioned/affixed within the working area 23 with the back surface 19 making contact with the subject's skin and the frontal surface side 21 providing display 15. |
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http://www.freepatentsonline.com/5031619.html
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| | Anemia and Increased Bleeding Time |
| | Incidentally, this seems like a good time to remind ourselves about an often-overlooked method to avoid excessive blood transfusions during the first week of life for VLBW infants. | | | We need to be careful that in our zeal to limit blood exposure in VLBW premature babies, that we do not increase their risk of serious bleeding problems, especially intraventricular hemorrhage (IVH). | | | Until better data about this risk is available, we would be wise to maintain hematocrits > 28 – 30 in VLBW babies during the first week of life (when the risk of IVH is greatest). |
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http://www.fsneo.org/JourClub/2-038.htm
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| | The Evaluation of Bleeding Disorders |
| | Postoperative bleeding at a surgical site is usually related to a local surgical problem. | | | Platelet function screen: The PFA-100 is a platelet function analyzer that is slowly supplanting the bleeding time in the clinical arena. | | | Jilma B. Platelet function analyzer (PFA-100): a tool to quantify congenital or acquired platelet dysfunction. |
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http://www.clevelandclinicmeded.com/diseasemanagement/hematology/bleeding/bleeding.htm
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| | Bleeding Time (Hemostasis Test) Principal Health News |
| | Also, the bleeding time test is sometimes performed as a preoperative test to determine a patient's likely bleeding response during and after surgery. | | | However, in patients with no history of bleeding problems, or who are not taking anti-inflammatory drugs, the bleeding time test is not usually necessary. | | | Before administering the test, patients should be questioned about what medications they may be taking. |
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http://www.principalhealthnews.com/topic/topic100586523
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| | Unexpected Bleeding Disorders -- Aledort et al. 2001 (1): 306 -- Hematology |
| | Definition of the bleeding tendency in factor XI-deficient kindreds—A clinical and laboratory study. | | | time, which is no longer accepted as a valid marker of the therapeutic | | | was no family history of bleeding; one aunt had gastric cancer. |
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http://www.asheducationbook.org/cgi/content/full/2001/1/306
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| | Bleeding Disorders |
| | The Bleeding time test has been largely replaced by assays such as the Platelet function analyzer test. | | | Most common use is monitoring warfarin anticoagulant therapy. | | | If increased, indicates recent blood clot formation and breakdown |
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http://www.labtestsonline.org/understanding/conditions/bleeding_disorders-5.html
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| | July 2000 - Platelet Closure Times |
| | It may also be useful to monitor the response of therapeutics, such as DDAVP infusions, renal dialysis, platelet and antiplatelet drug therapy. | | | As a consequence many clinicians no longer use BT. | | | For questions or further information on regarding Closure Times, please contact |
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http://www.itxm.org/TMU2000/tmu7-2000.htm
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| | BLEEDING TIME |
| | Method: The bleeding time is subject to many technical and physiological variables. | | | The modified Ivy technique must be performed by experienced laboratory staff. | | | Although it may be abnormal in von Willebrand’s disease, inherited disorders of platelet function, uraemia, myeloproliferative disorders and after aspirin and NSAID use, its ability to predict surgical bleeding and/or the need for therapeutic cover in these situations is very limited.Bleeding time can also be prolonged after ingestion of some foods eg garlic. |
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http://www.npg.co.za/RCPA/bleedin2.htm
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| | Mucosal Bleeding Time |
| | Indications to perform this test: This is a simple clinical procedure used to evaluate the primary clotting system of a patient suspected to have a | | | The blood is blotted off of the skin with a piece of filter paper. | | | Primary bleeding disorders are either due to inadequate platelet numbers or improperly functioning platelets, but do not involve the coagulation factors. |
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http://www.vetmed.wsu.edu/courses_vm546/Content_Links/Clinical_Pathology/Lab_Tests/bleeding_time.htm
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| | Transfusion Medicine #3 |
| | "The preoperative bleeding time test lacks clinical benefit: College of American Pathologists' and American Society of Clinical Pathologists' position article." Archives Of Surgery 133(2): 134-9. | | | When questions arise concerning testing for platelet disorders, consultation with the medical director of the coagulation laboratory may prove useful. | | | The most common cause of platelet dysfunction is drug related. |
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http://hsc.unm.edu/cme/creditApp/Transfusion_Med_3.html
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| | Bleeding Time : BT |
| | *to clear a patient for surgery given clinical evidence of bleeding, other laboratory abnormality(ies) or a positive history of bleeding. | | | The test was used to evaluate patients who presented with purpura. | | | A good history has been shown, repeatedly, to be more sensitive to bleeding disorders than any hemostatic screening test. |
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http://www.mclno.org/webresources/kbase/Hemostasis/BT.html
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| | NEJM -- Deamino-8-D-arginine vasopressin shortens the bleeding time in uremia |
| | Our findings indicate that 1-deamino-8-D-arginine vasopressin can be used for temporary correction of bleeding time and may prevent surgical bleeding in patients with uremia. | | | The compound was given to nine additional patients with acute or chronic renal failure and prolonged bleeding times, before major surgery or renal biopsy. | | | In these patients, shortening of the bleeding time was associated with normal hemostasis. |
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http://content.nejm.org/cgi/content/short/308/1/8
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| | Bleeding Time |
| | Methodology A trained healthcare professional makes a small incision on the patient's arm, and every 30 seconds gently blots the blood with filter paper to see if the bleeding has stopped. | | | Clinicians may wish to inform the patient that a scar might form as a result of a bleeding time test, particularly if the patient has a history of keloids. | | | Additional Information The bleeding time can be prolonged in von Willebrand disease and other hereditary platelet function disorders, uremia, macroglobulinemia, and a variety of other conditions. |
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http://www.mgh.harvard.edu/labmed/lab/coag/handbook/CO006500.htm
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| | BLEEDING TIME |
| | The Laboratory has not established a reference range for children. | | | Bleeding times will not be done on thrombocytopenic patients if platelet count is less than 50 X 10 | | | Bleeding time should not be done unless patient has forearm free of IV's, vascular shunts, arterial lines, or heparin locks. |
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http://www.healthsystem.virginia.edu/internet/labtests/clinical/b/bldx.cfm
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| | Healthopedia.com - Bleeding Time |
| | This test measures how long it takes a person to stop bleeding after the skin is cut. | | | Usually a blood pressure cuff is placed on the upper arm and inflated. | | | You are here : Healthopedia.com > Medical Encyclopedia > Tests and Exams > Bleeding Time |
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http://www.healthopedia.com/bleeding-time
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| | WOMENS-HEALTH Messages for November, 1999: Re: Prolonged bleeding time |
| | This information is not intended to supplant the need for you to consult with your physician prior to choosing therapeutic options and/or interventions. | | | NSAIDs including Advil and aspirin can cause increased bleeding times but one dose doesn't usually do that much. | | | Keeping that in mind, if repeat testing was all normal, including bleeding time, the Advil must have been the culprit. |
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http://forums.obgyn.net/womens-health/WHF.9911/0144.html
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| | Bleeding Time |
| | A small (1-2 mm deep) stab wound is made in the earlobe (Duke technique) or the forearm (Ivy technique). | | | The bleeding time is the time from the stab wound to the time that no further bleeding is detectable. | | | The Bleeding Time is a measure of how quickly blood clots, using platelets, coagulation factors, and small vessel vasospasm. |
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http://www.md.pims.org/operationalmed/Lab/Bleeding%20Time.htm
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| | MedlinePlus Medical Encyclopedia: Bleeding disorders |
| | Calling your health care provider Return to top | | | Others are developed during certain illnesses (such as vitamin K deficiency or severe liver disease), or treatments (such as use of anticoagulant drugs or prolonged use of antibiotics). | | | Bleeding disorders are a group of conditions of the blood clotting (coagulation) system, in which bleeding following an injury is prolonged and excessive. |
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http://www.nlm.nih.gov/medlineplus/ency/article/001304.htm
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| | Bleeding time test, Eastern Carolina |
| | For this test, a health professional puts a blood pressure cuff on your upper arm and inflates it slightly. | | | The health professional will time how long it takes for the bleeding to stop in each incision. | | | If the incisions take too long to clot, you may have a bleeding disorder. |
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http://www.uhseast.com/130565.cfm
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| | BLEEDING TIME Care Guide Information |
| | Apply pressure or a pressure bandage to the puncture site. | | | A bleeding time is a test to see if platelets are working as they should. | | | This test often is done before surgery to make sure you do not bleed too much during or after surgery. |
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http://www.drugs.com/CG/BLEEDING_TIME.html
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| | Pregnancy Testing Index of Articles |
| | Although it would be nice to be able to visit our doctor and get all hooked up with electrodes, inflatable cuffs, probes, needles and catheters and have a read-out telling | | | Any form of exercise was strictly prohibited by doctors and feared by concerned fathers. | | | According to the Center for Disease Control and Prevention (CDC), the number of Americans over 50 who are infected with HIV have grown over 5 times (16,300 people in 1995, to 90,600 in 2003). |
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http://www.life-healthy.com
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| | Hemostasis and Its Regulation -- Answer |
| | Thrombin time is prolonged in patients with severe liver disease and DIC and those undergoing heparin therapy. | | | The bleeding time is difficult to standardize, and a normal bleeding time does not predict the safety of a surgical procedure. | | | Factor VII levels are measured in patients who have a prolonged PT; it is a test of the extrinsic system. |
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http://www.medscape.com/content/2004/00/47/98/479839/ans12.html
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| | Bleeding Time |
| | Bleeding time may be normal in disorders of the coagulation system. | | | Bleeding time is elevated in the following conditions: decreased platelet count decreased platelet function increased prothrombin time uremia DIC certain drugs: aspirin and other anti-inflammatory drugs | | | The mechanism to stop bleeding involves vascular contraction, platelet function, and the participation of the non-clotting portion of the Factor VIII. |
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http://www.thebiotechdictionary.com/term/bleeding_time
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| | Notoginseng Cuts Bleeding Time in Half |
| | Modern medicine has no treatment for one common problem—external bleeding, which can range from a simple nosebleed to life-threatening blood loss from trauma. | | | The researchers are hope- ful that notoginseng could help people who experience excessive bleeding as a result of taking anticoagulants. | | | The animals that received no treatment bled for 17.6 minutes. |
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http://www.newhope.com/nutritionsciencenews/nsn_backs/Dec_01/news3.cfm
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| | Diagnostic Handbook |
| | Acquired platelet dysfunction also occurs in immune thrombocytopenia (ITP) where the bleeding time is prolonged more than predicted for the reduced platelet count, in myeloproliferative disorders (essential thrombocythaemia), in paraproteinaemias (MGUS, myeloma) and sometimes in association with viral illness. | | | The bleeding time is a poor predictor of the risk of surgical bleeding. | | | It is a useful test in the diagnosis of inherited minimal bleeding disorders associated with a platelet function defect such as von Willebrand's disease. |
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http://www.dml.co.nz/hbook/5a65045.htm
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| | Bleeding time |
| | Bleeding time is usually within a normal range when the platelet count is greater than 100,000 per microliter. | | | Normal bleeding time is largely dependant upon both the number and function of platelets. | | | A patient history of: von Willebrand's disease, thrombcytopenia, inherited platelet dysfunction, recent NSAID or antihistamine use can all prolong bleeding time. |
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http://www.rnceus.com/coag/coagbleed.html
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| | Bleeding Time |
| | No evidence that bleeding time is useful in predicting bleeding in individual patient |
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http://www.wramc.army.mil/departments/Medicine/Nephrology/education/Lectures/ublood/tsld013.htm
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| | Penn State Faculty Research Expertise Database (FRED) |
| | Desmopressin control of surgical hemorrhage secondary to prolonged bleeding time. | | | We report a case of surgical hemorrhage secondary to prolonged bleeding time of unexplained origin controlled with desmopressin. | | | Desmopressin has been used as a hemostatic agent in numerous hematological and nonhematological diseases. |
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http://fred.hmc.psu.edu/ds/retrieve/fred/publication/3361648
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| | Resource Library: Find information on Bleeding time at MerckSource |
| | Additional conditions under which the test may be performed: | | | Certain medications can interfere with platelet function and therefore may alter test results. | | | A blood pressure cuff is placed on the upper arm and inflated. |
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http://www.mercksource.com/pp/us/cns/cns_hl_adam.jspzQzpgzEzzSzppdocszSzuszSzcnszSzcontentzSzadamzSzencyzSzarticlezSz003656zPzhtm
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| | Procedure Bleeding Time |
| | Bleeding time results will be affected when the platelet count is less than 100,000 mm3. | | | The patient should be off aspirin for at least 10 days prior to testing. | | | Aspirin and anti-inflammatory medication will prolong the bleeding time result. |
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http://health.ucsd.edu/labref/P428.html
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| | British Journal of Pharmacology - Abstract of article: Antithrombotic effects of YM-60828, a newly synthesized factor ... |
| | The effects of YM-60828, a newly synthesized factor Xa inhibitor, were investigated to analyse the relationship between its antithrombotic effects and its prolongation of template bleeding time in rats. | | | Antithrombotic effects of YM-60828, a newly synthesized factor Xa inhibitor, in rat thrombosis models and its effects on bleeding time | | | British Journal of Pharmacology - Abstract of article: Antithrombotic effects of YM-60828, a newly synthesized factor Xa inhibitor, in rat thrombosis models and its effects on bleeding time |
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http://www.nature.com/bjp/journal/v123/n1/abs/0701566a.html
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| | Bleeding Time and Prediction of Surgical Bleeding |
| | Elevated BT - no difference in bleeding, chest tube output, need for transfusions | | | BT of only moderate sensitivity and specificity, therefore many false positives in low-risk populations | | | Bleeders and non-bleeders have same mean bleeding time |
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http://www.bcm.edu/medicine/hema-onco/lectures/postop/sld012.htm
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| | Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice. |
| | Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.Activation of P2Y1 resulted in increased intracellular calcium but no alteration in cyclic adenosine monophosphate (cAMP) levels. | | | P2Y1-deficient platelets partially aggregated at higher ADP concentrations, and the lack of P2Y1 did not alter the ability of ADP to inhibit cAMP, indicating that platelets express at least one additional ADP receptor. | | | Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice. |
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http://www.pdg.cnb.uam.es/UniPub/iHOP/gp/2021467.html
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