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| | Bile - Wikipedia, the free encyclopedia |
 | | Besides its digestive function, bile serves as the route of excretion for the hemoglobin breakdown product (bilirubin) which gives bile its colour. | | | This mixture, applied to textiles a few hours before washing, is a traditional and rather effective method for removing various kinds of tough stains. | | | Emulsified droplets then are organized into many micelles which increases absorption. |
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http://en.wikipedia.org/wiki/Bile_salts
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| | [Frontiers in Bioscience 3, d176-193, February 15, 1998] |
| | It appears that the neutral pathway may be the main pathway under most physiologic conditions and the dominant pathway when bile acid feedback is interrupted, i.e. | | | The classic pathway with modifications of cholesterol nucleus preceding oxidation and cleavage of the side chain is believed to be the major pathway in the rat. | | | Axelson and Sjovall (5) studied plasma concentration of c27-acids in patients with liver disease and proposed two pathways of bile acid synthesis in man. They referred the classic pathway as a neutral pathway which is most important when cholesterol 7alpha-hydroxylase activity is high. |
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http://bioscience.igh.cnrs.fr/1998/v3/d/chiang/3.htm
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| | VI. Drug Therapy -- 106 (25): 3303 -- Circulation |
| | Sequestrant therapy can produce a variety of gastrointestinal | | | Flushing of the skin is common with the crystalline | | | Colesevelam, a recently marketed drug, is a much more potent bile |
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http://circ.ahajournals.org/cgi/content/full/106/25/3303
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| | Colestipol |
| | The STC level changes were not correlated with concomitant changes in low-density lipoprotein-cholesterol (LDL-C) during any of the treatment regimens. | | | In adult patients treated with cholestyramine, gastrointestinal complaints, especially constipation, abdominal pain and unpalatability are most frequently observed. | | | Abstract: Cholestyramine, colestipol, clofibrate, gemfibrozil, nicotinic acid (niacin), probucol, neomycin, and dextrothyroxine are the most commonly used drugs in the treatment of hyperlipoproteinaemic disorders. |
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http://home.caregroup.org/clinical/altmed/interactions/Drugs/Colestipol.htm
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| | Lipids Online Slides: bile acid resins, bile acid sequestrants, efficacy |
| | Combination Lipid-Altering Drug Therapy with Statins (Harold Bays, MD, FACP) | | | Combination Lipid-altering Drug Therapy with Statins: An Update (Harold Bays, MD, FACP) | | | Unfortunately, the clinical use of bile acid resins such as cholestyramine and colestipol has been limited because of common gastrointestinal side effects and potential drug interactions with commonly prescribed concomitant drugs. |
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http://www.lipidsonline.org/slides/slide01.cfm?q=bile+acid+resins
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| | Method of reducing gastrointestinal side effects associated with orlistat treatment - Patent 6756364 |
| | In addition, the present invention refers to a method of treatment of obesity in a human in need of such treatment which comprises administration to the human of a therapeutically effective amount of a lipase inhibitor and a therapeutically effective amount of a bile acid sequestrant. | | | This method comprises administering to a patient being treated with a lipase inhibitor an amount of a bile salt sequestrant effective to reduce the side effects associated with the lipase inhibitor treatment. | | | The reduction of unpleasant gastrointestinal side effects can improve the quality of life in sensitive patients during treatment with a lipase inhibitor and may further enhance compliance of the patients with drug intake and thus enhance the therapeutic benefit. |
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http://www.freepatentsonline.com/6756364.html
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| | BILE ACID SEQUESTRANT |
| | A class of medications that lower cholesterol by trapping bile and fats in the intestine. | | | Copyright DSHI Systems, Inc., Last updated Feb. 2002 |
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http://www.medhelp.org/glossary2/new/GLS_0737.HTM
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| | NHLBI-CHD Cholesterol Lowering Medicines |
| | Talk to your doctor about the best time to take this medicine, especially if you take other medications. | | | Sequestrant therapy may produce a variety of symptoms including constipation, bloating, nausea, and gas. | | | Although sequestrants are not absorbed, they may interfere with the absorption of other medicines if taken at the same time. |
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http://www.nhlbisupport.com/chd1/meds2.htm
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| | Health Library - |
| | Calcium and zinc balances in rats chronically fed the bile salt-sequestrant cholestyramine (Questran). | | | For additional evidence-based information on diseases, conditions, symptoms, diagnosis, treatment and wellness issues, continue searching the Healthwise Knowledgebase. | | | Cholestyramine (Questran®) and colestipol (Colestid®) are bile acid sequestrants-a class of drugs that binds bile acids, prevents their reabsorption from the digestive system, and reduces cholesterol levels. |
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http://www.coxnet.org/library/healthguide/en-us/Cam/topic.asp?hwid=hn-1322001
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| | Bile acid sequestrants for high cholesterol |
| | People with the following conditions should not take sequestrants: | | | For people with very high cholesterol levels (over 240 mg/dL or 6.21 mmol/L), these drugs also may be prescribed in combination with medications called statins. | | | However, they may be beneficial when combined with statins. |
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http://hw.healthdialog.com/kbase/topic/detail/drug/hw114997/detail.htm
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| | Tables |
| | Initial drug therapy for elevated LDL should be with a statin | | | Fibrates may be used in Stage 5 CKD 1) for patients with triglycerides >/=500; and 2) for patients with triglycerides >/=200 mg/dl with non-HDL cholesterol >/=130 mg/dl who do not tolerate statins | | | Initial drug therapy for elevated LDL should be with a statin, bile acid sequestrant, or nicotinic acid |
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http://www.medscape.com/content/2004/00/49/16/491665/491665_tab.html
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| | ezetimibe |
| | Continue to take any other lipid-lowering drugs that have been prescribed for you. | | | If used as part of combination therapy; give drug at the same time as HMG Co-A reductase inhibitors and > 2 hr before or > 4 hr after bile acid sequestrants. | | | Determine that patient has been on low cholesterol diet and exercise program for at least 2 wk before starting ezetimibe. |
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http://wellcaremc.com/drugs/mg/ezetimibe.htm
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| | Bile Acid Sequestrants, medications to lower cholesterol on MedicineNet.com |
| | Improving Your Cholesterol Profile: Heart Attack Prevention Series - Medical information about cholesterol, produced by doctors for patients experiencing elevated cholesterol levels to make informed health decisions | | | Bile acid sequestrants are not absorbed into the body and therefore they do not have systemic side effects (affecting other organs). | | | Bile acid sequestrants such as cholestyramine (Questran), colestipol (Colestid), and colesevelam (Welchol) are medications for lowering LDL cholesterol. |
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http://www.medicinenet.com/script/main/art.asp?subject=bile_acid_sequestrants
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| | [No title] |
| | If LDL goal not achieved, intensify drug therapy or refer to a lipid specialist | | | If LDL goal not achieved, intensify LDL-lowering therapy | | | Consider higher dose of statin or add a bile acid sequestrant or nicotinic acid |
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http://hin.nhlbi.nih.gov/ncep_slds/atpiii/part5txt.htm
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| | Arch Intern Med -- Abstract: Colesevelam Hydrochloride (Cholestagel): A New, Potent Bile Acid Sequestrant Associated ... |
| | RELATED ARTICLES IN Archives of Internal Medicine Reader's Choice: Continuing Medical Education | | | Bruce Gordon, MD Peter Jones, MD Julie Samuels, MD Stuart Weiss, MD Jonathon Isaacsohn, MD Phillip Toth, MD Steven K. Burke, MD Arch Intern Med. | | | Arch Intern Med -- Abstract: Colesevelam Hydrochloride (Cholestagel): A New, Potent Bile Acid Sequestrant Associated With a Low Incidence of Gastrointestinal Side Effects, September 13, 1999, Davidson et al. |
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http://archinte.ama-assn.org/cgi/content/abstract/159/16/1893
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| | Bile Acid Sequestrant Drugs - Swedish Medical Center, Seattle, Washington |
| | The bile acid sequestrant drugs are among the earliest class of medications used to lower cholesterol. | | | It appears, however, that only folate supplementation may be needed by individuals on long-term therapy with bile acid sequestrants. | | | Always seek the advice of your physician or other qualified health provider prior to starting any new treatment or with any questions you may have regarding a medical condition. |
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http://www.swedish.org/111895.cfm
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| | Familial hypercholesterolemia - Wikpedia |
| | In case statins are not effective, either a drug from the fibrate or bile acid sequestrant class can be added, as well as nicotinic acid/acipimox. | | | Homozygous FH Homozygous FH is a different story. | | | As previously mentioned, the LDL levels are much higher and the most effective treatments (statins) require at least one copy of the functional LDL receptor gene. |
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http://www.bostoncoop.net/~tpryor/wiki/index.php?title=Familial_hypercholesterolemia
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| | Pharmacology |
| | NSAID s, anticholinergic, haemostatic drug, antifibrinolytic, Hormone Replacement Therapy, bone regulator, beta-receptor agonist, follicle stimulating hormone, luteinising hormone, LHRH gamolenic acid, gonadotropin release inhibitor, progestogen, dopamine agonist, oestrogen, prostaglandin, gonadorelin, clomiphene, tamoxifen, Diethylstilbestrol | | | For the gastrointestinal tract or digestive system === antacid, reflux suppressant, antiflatulent, antidopaminergic, antispasmodic, proton pump inhibitor, H2 antagonists, cytoprotectant, prostaglandin analogue, laxative, antidiarrhoeal, bile acid sequestrant s, opioid |
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http://www.serebella.com/encyclopedia/article-Pharmacology.html
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| | NDEP National Diabetes Education Program |
| | Notify physician immediately of muscle pain.Use caution if combining with fibric acid derivatives or bile acid sequestrants (described below).(increased risk of rhabdomyolysis) | | | Main action: Lowers LDL cholesterol; inhibits absorption of cholesterol.If used with a statin, take together. | | | If used with bile acid sequestrant, ezetimibe should be taken 2 hr before or 4 hr after bile acid sequestrant. |
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http://ndep.nih.gov/diabetes/wtmd/diabets_suppl_3.htm
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| | Bile Acid Sequestrant |
| | The next step, after you have been diagnosed with a disease, is to find out what is the specific cause, and then choose supplements that address that cause, as well as supplements that alleviate the symptoms of the disease. | | | Bile acid sequestrants impair the absorption of several nutrients, including vitamins A, E, K, and B12, iron, and calcium. |
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http://www.naturdoctor.com/Chapters/Drugs/Bile_Acid_Sequestrant.html
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| | bile acid: Definition and Much More From Answers.com |
| | Any of several acids formed in the liver that commonly occur in the bile in combination with glycine or taurine as sodium salts. | | | bile acid: Definition and Much More From Answers.com | | | Note: click on a word meaning below to see its connections and related words. |
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http://www.answers.com/topic/bile-acid
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| | Cola Nut |
| | The effect of Cola acuminata and Cola nitida on gastric acid secretion. |
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http://www.al-hikmah.org/cola-nut.asp
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