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| | Autoimmune Polyendocrine Syndromes |
 | | In the first stage, a patient's HLA genotype plays the key role in his or her predisposition to the development of autoimmune polyendocrine syndrome type II. |  | | Obvious long-term goals are therapies that address the underlying |  | | Genes that lower the set point for maintaining tolerance, such |
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http://www.medical-journals.com/r04_135.htm
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| | APECED Syndrome,Autoimmune Endocrinopathy-Candidiasis-Ectodermal Dystrophy,Autoimmune Polyglandular Disease Type ... |
 | | Although association between the HLA system and autoimmune conditions has been observed in numerous cases, HLA represents at best only part of the genetic susceptibility factors. |  | | I despair at the waste of time and effort, knowing others have to trudge the same hard path to learn how to live harmoniously with APECED. |  | | Clinical variation of autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) in a series of 68 patients |
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http://www.icomm.ca/geneinfo/apeced.htm
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| | Autoimmune polyendocrine syndrome - Wikipedia, the free encyclopedia |
 | | Rather, patients are at a higher risk when they carry a particular HLA genotype (DQ2, DQ8 and DRB1*0404). |  | | There are three "autoimmune polyendocrine syndromes", and a number of other diseases which have endocrine autoimmunity as one of their features. |  | | Most patients develop diabetes and diarrhea as neonates and many die due to autoimmune activity against many organs. |
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http://en.wikipedia.org/wiki/Autoimmune_polyendocrine_syndrome
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| | Diabetes mellitus |
 | | Risk of diabetes is higher with chronic use of several medications, including high dose glucocorticoids, some cancer chemotherapy agents (especially L-asparaginase), and some of the antipsychotics and mood stabilizers (especially phenothiazines). |  | | It may be caused by a number of diseases, such as hemochromatosis and polycystic ovary syndrome, and can also be caused by certain types of medications (e.g., long-term steroid use). |  | | Many medical conditions are associated with a higher risk of various types of diabetes and warrant screening. |
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http://www.sciencedaily.com/encyclopedia/diabetes_mellitus
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| | Diabetes Monitor - autoimmune endocrine failure syndromes |
 | | Autoimmune endocrine failure syndromes may include diabetes and other endocrine and non-endocrine problems. |  | | (1) Autoimmune: Disorders of the body's immune system in which the immune system mistakenly attacks and destroys body tissue that it believes to be foreign. |  | | This syndrome might include any or most of the following disorders: |
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http://www.diabetesmonitor.com/aefs.htm
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| | Diabetes Care: Comparative Analysis of Organ-Specific Autoantibodies and Celiac Disease- Associated Antibodies in Type ... |
 | | This overlap of different autoimmune disorders has led to the concept of autoimmune polyendocrine syndrome (APS) with the clinical or subclinical involvement of several organs in the same subject or family [2-4]. |  | | The first evidence that type 1 diabetes might be a disease of autoimmune origin came from the observation that type 1 diabetes is often associated with other endocrine autoimmune disorders. |  | | Based on the hypothesis that the frequent coexistence of these diseases can be explained at least in part by their similar genetic background, we addressed the question whether first-degree relatives of type 1 diabetic patients might be significantly affected by these disorders. |
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http://www.findarticles.com/p/articles/mi_m0CUH/is_1_24/ai_69493723
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| | Medical Dictionary: Autoimmune endocrine failure syndrome - WrongDiagnosis.com |
 | | More information on medical condition: Polyendocrine deficiency syndrome : |  | | Autoimmune endocrine failure syndrome : Type of Polyendocrine deficiency syndrome. |  | | We show you all these ads in order to provide this free site; give your feedback. |
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http://www.wrongdiagnosis.com/medical/autoimmune_endocrine_failure_syndrome.htm
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| | Gene Information |
 | | Defects in this gene cause the autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). |  | | Anderson MS, et al used aire- deficient mice to test the hypothesis that this transcription factor regulates autoimmunity by promoting the ectopic expression of peripheral tissue- restricted antigens in medullary epithelial cells of the thymus. |  | | Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED), also known as autoimmune polyglandular syndrome Type I (APS1), is an autosomal recessive autoimmune disease caused by mutations in a gene designated as AIRE (autoimmune regulator). |
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http://ovary.stanford.edu/4_display.html?rec=1092
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