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| | Atherosclerotic plaque inflammation: The final frontier? |
 | | Recent work has provided evidence that lipid-lowering therapy prevents acute coronary complications in patients by limiting inflammation and, in turn, improving features associated with instability and thrombogenicity in atheromata (ie, ‘stabilization’) rather than merely shrinking the plaque (3,7). | | | Previous studies have localized MMPs in macrophages of human and experimental atheromata. | | | These future approaches should help to prevent acute complications of vascular inflammation more effectively and individually. |
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http://www.pulsus.com/CARDIOL/20_06/aika_ed.htm
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| | [No title] |
| | The analysis in the MI and LOH positive cases was repeated at least twice and the results were highly reproducible." In their discussion, Hatzistamou et al (1996, p.187) comment: "Originally, LOH was reported in the development of human tumours and represents a manifestation of the recessive behavior of the onco-suppressor genes. | | | Although the incidence of LOH reported in the present investigation is not very high, this is the first report to our knowledge which demonstrates LOH in atherosclerotic lesions. | | | During a person's lifetime, the arterial SMCs accumulate exposure to mutagens (including ionizing radiation from natural sources and especially from medical XRAYS). |
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http://www.ratical.org/radiation/CNR/RMP/RAMPadd3.txt
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| | Welcome to LifeScore.com! - Key Articles About Electron Beam Computed Tomography for Coronary Calcium |
| | The relative risk for a cardiac event in patients with VCS progression was 10 fold greater than that of patients with stabilization of VCS. | | | The 40 treated patients who had average LDL cholesterol levels of at least 120 had a measurable increase in mean calcium volume score (mean change, +25 +/-22%, p<0.001), although it was smaller than the increase in the untreated patients. | | | EBCT is the only noninvasive test that can be used to assess response to therapeutic interventions aimed at shrinking coronary plaque. |
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http://www.lifescore.com/eb-articles.htm
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| | BFML: Research: Atherosclerotic Plaque Rupture |
| | The objective of this project is to integrate the technologies needed to quantitatively determine an individual patient's risk for embolism due to plaque rupture. | | | The current criterion for predicting a patients risk for stoke is based on the percent stenosis (diameter reduction) of the carotid artery and has no physical or biochemical basis for assessing the risk for an embolic stroke. | | | Among the several causes are hemorrhage, embolism, thrombosis, and aneurysm rupture. |
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http://www.umbc.edu/bfml/apr.html
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| | Atherosclerotic Plaque Rupture |
| | Active cathepsins appear to be associated with foam cells at the shoulders of the plaque. | | | · Dr Ken Rodgers found that levels of cathepsin activity are much higher in atherosclerotic plaques than in normal tissue, and that cathepsin S is of particular interest as it is active at physiological pH. | | | · Dr Alistair Miller is currently investigating the release of proteases by human monocyte-derived macrophages co-cultured with atherosclerotic plaque fibrous cap. |
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http://www.bris.ac.uk/Depts/BHI/chris/chrisres.htm
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| | Atherosclerotic Plaque - Artery with |
| | Macrophages (green) infiltrate plaques that eventually rupture, causing ischemia in patients with hypercholesterolemia (see 103-239 for full arterial view). | | | I work in layers so that any image can be modified to fit your layout or animation. | | | For a searchable website of all my images, please visit www.peggerrity.com |
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http://www.indexedvisuals.com/index2/103-208.htm
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