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| | Friedreich's Ataxia Fact Sheet: National Institute of Neurological Disorders and Stroke (NINDS) |
 | | The ataxia of Friedreich's ataxia results from the degeneration of nerve tissue in the spinal cord and of nerves that control muscle movement in the arms and legs. | | | Genetic counselors can help explain how Friedreich's ataxia is inherited and its effect on the patient and the family. | | | Armed with what they currently know about frataxin and Friedreich's ataxia, scientists are working to better define frataxin's role, clarify how defects in iron metabolism may be involved in the disease process, and explore new therapeutic approaches for the disease. |
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http://www.ninds.nih.gov/disorders/friedreichs_ataxia/detail_friedreichs_ataxia.htm
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| | Ataxia |
| | The age of onset is before adolescence; however, some patients with Friedreich ataxia may have preserved reflexes and later age of onset. | | | For Friedreich ataxia, carrier testing of relatives of an affected person may be appropriate so that appropriate genetic counseling can be provided. | | | Finally, establishing advance care directives will help the patient with progressive degenerative ataxia ensure that his care is as he would like even at a time when he is unable to communicate effectively. |
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http://www.medlink.com/scip.asp?suser=9999&uid=mlt000mz
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| | FRIEDREICHS ATAXIA |
| | This condition is caused by degeneration of nerve tissue in the spinal cord and of nerves that extend to peripheral areas such as the arms and legs. | | | The early ambulatory period is characterised by a decrease in or absence of muscle reflexes in addition to an unsteady gait. | | | The ataxia in the arms, head, and neck continue to worsen during the non ambulatory stage and it becomes increasingly difficult to sit upright. |
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http://www.mda.org.au/specific/mdafa.html
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| | Ataxia |
| | Friedreich's Ataxia is a hereditary neuromuscular syndrome characterized by slow degenerative changes of the spinal cord and the brain. | | | The National Ataxia Foundation is a nonprofit organization established in 1957 with the primary mission of encouraging and supporting research into Hereditary Ataxia, a group of neurological disorders which are chronic and progressive conditions affecting coordination. | | | Locating families affected by ataxia or at risk for ataxia in order to offer information and education. |
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http://www.alaska.net/~mnewell/html/ataxia.html
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| | Hereditary Ataxia Overview |
| | Ataxia may result from dysfunction of the cerebellum and its associated systems, lesions in the spinal cord, peripheral sensory loss, or any combination of these three conditions. | | | Genetic counseling and risk assessment depend on determination of the specific ataxia subtype in an individual. | | | The SCA4 families in Japan also have late onset (mean 55 years) and late-occurring hearing loss. |
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http://www.geneclinics.org/profiles/ataxias/details.html
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| | MEDSTUDENTS-NEUROLOGY |
| | Another important find is that the vestibular ataxia is gravity-dependent, which means that incoordination of limb movements cannot be demonstrated when the patient is examined lying down but becomes apparent when the patient attempts to stand or walk. | | | Most commonly the term is only used to describe an unsteadiness of walking, but it is not correct since the same principles apply to disturbances in coordinated movements affecting the upper extremities, the speech mechanisms and the eye movements. | | | Nevertheless, their anatomical and physiological basis are very distinct, sometimes poorly understood, and are beyond the scope of this review. |
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http://www.medstudents.com.br/neuro/neuro2.htm
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| | MDVU - Pediatric Movement Disorders - Ataxia |
| | Ataxia may affect any part of the body. | | | When it affects the arms and hands, it may cause tremor due to over-correction of inaccurate movements, past-pointing when an attempted reach overshoots the target, and poor performance of regular, repeated movements, such as hand clapping. | | | On careful examination, the eyes may be observed to overshoot or undershoot their mark, with "catch-up" movements. |
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http://www.mdvu.org/library/pediatric/ataxia
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| | Ataxia - PetPlace.com |
| | Ataxia may be defined as the inability to coordinate the voluntary movement of muscles. | | | Be prepared to tell your veterinarian when the problem began, if the ataxia is constant or intermittent, your birds chewing habits, the type of diet your bird is on, and of any potential exposure to other birds. | | | These are often caused by damage to the spinal cord, inner ear or brain. |
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http://www.petplace.com/birds/ataxia/page1.aspx
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| | National Ataxia Foundation |
| | This three-day conference is a comprehensive look at ataxia through experts in the field of ataxia research, genetics, physical therapy, living with ataxia, coping skills, and much more. | | | The Foundation is dedicated to improving the lives of persons affected by ataxia through support, education, and research. | | | Readers should seek their own medical advice by a qualified physician in the treatment and care of their condition. |
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http://www.ataxia.org/home.htm
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| | ataxia |
| | Though most commonly used to describe the way a person walks, this condition can affect any of the muscles in the body. | | | People with ataxia have irregular or awkward movements. | | | An example of ataxic movement would be someone who is clearly drunk. |
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http://www.northmemorial.com/healthencyclopedia/content/3121.asp
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| | eMedicine - Friedreich Ataxia : Article by Eric Ciliberti, MD |
| | The cerebellar ataxia is explained by loss of the lateral and ventral spinocerebellar tracts and involvement of the Clarke column, dentate nucleus, superior vermis, and dentatorubral pathways. | | | In this case of a 21-year-old patient with a 2-year history of gait ataxia, dysarthria, and absent lower extremity reflexes, motor and sensory involvement had not yet become clinically apparent. | | | Dysarthria, areflexia, motor weakness of the lower extremities, extensor plantar responses, and distal loss of joint position and vibration senses are not found in all patients within the first 5 years, but are eventually universal. |
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http://www.emedicine.com/neuro/topic139.htm
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| | eMedicine - Ataxia-Telangiectasia : Article by Sergiusz Jozwiak, MD, PhD |
| | Intact sensation and a negative Romberg sign are helpful in differentiating the cerebellar ataxia of A-T from Friedreich ataxia, in which the ataxia is predominantly spinal or sensory and the Romberg sign is positive. | | | The facies is usually relaxed, dull, sad, and seemingly inattentive, which is in sharp contrast to the cheerful, alert appearance when the patient is smiling. | | | Woods CG, Taylor AM: Ataxia telangiectasia in the British Isles: the clinical and laboratory features of 70 affected individuals. |
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http://www.emedicine.com/derm/topic691.htm
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| | Friedreich Ataxia |
| | Friedreich ataxia (FRDA) is characterized by slowly progressive ataxia with onset usually before the age of 25 years typically associated with depressed tendon reflexes, dysarthria, Babinski responses, and loss of position and vibration senses. | | | All affected individuals have generalized areflexia followed by a peripheral neuropathy and quadriplegia with loss of ambulation about seven to ten years after onset. | | | PCR or Southern blot analysis of the GAA repeat reveals homozygous expanded alleles in the vast majority of individuals |
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http://www.geneclinics.org/profiles/friedreich/details.html
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| | Welcome to Ataxia UK |
| | Ataxia UK hosted a one day conference in London for researchers on 21 September 2005 on therapeutic approaches for the ataxias. | | | We support people affected by ataxia with research, information, welfare grants, campaigning and the opportunity to meet and help others in a similar position. | | | Recent research suggests that the cerebellar ataxias may be much more prevalent than previously suspected. |
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http://www.ataxia.org.uk
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| | ataxia - multiple sclerosis encyclopaedia |
| | In other conditions, it can also result from damage to the eighth cranial nerve leading from the balance organs in the inner ear. | | | Because the cerebellum is responsible for synchronising voluntary muscle movement throughout the body, cerebellar ataxia can result in: | | | Ataxia is most often applied to unsteadiness in walking but it also refers to upper body incoordination and dysfunction in eye movements and speech. |
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http://www.mult-sclerosis.org/ataxia.html
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| | Spinocerebellar Ataxia |
| | Molecular and clinical analyses of spinocerebellar ataxia type 8 in Japan. | | | A recent trial of Idebenone, a free radical scavenger, resulted in modest reductions in cardiac hypertrophy (Mariotti et al, 2003). | | | ataxia with sensory neuropathy, vomiting and gastrointestinal pain. |
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http://www.dizziness-and-balance.com/disorders/central/cerebellar/sca.htm
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| | Ataxia: Recessive |
| | Similar locus to Early onset cerebellar ataxia with retained reflexes | | | Early onset cerebellar ataxia with retained tendon reflexes (EOCA) | | | Ataxia: Dysarthria; Legs; Postural and Gait disorder; Dysmetria |
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http://www.neuro.wustl.edu/neuromuscular/ataxia/recatax.html
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| | Ataxia |
| | (Bilingual) Enables families of children affected by ataxia telangiectasia to seek information and share thoughts with other families. |
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http://www.webmd.com/hw/health_guide_atoz/shc29ata.asp
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| | Ataxia - MayoClinic.com |
| | The term "ataxia" describes a lack of muscle coordination when performing voluntary movements. | | | It may affect any part of the body. | | | Ataxia is usually caused by damage to a part of the brain called the cerebellum, which is responsible for muscle coordination. |
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http://www.mayoclinic.com/health/ataxia/AN00117
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| | Random Dance - Sadler's Wells - June 2004 |
| | AtaXia redraws the traditional hierarchies of dance to generate a fresh and radical look at human physicality. | | | Deliberately interfering with Random's sophisticated ability to co-ordinate muscular movement, AtaXia explores a dislocating loss of control. | | | Joining them will be Sarah Seddon Jenner, the ataxic patient that Wayne McGregor has been working with during the creation of AtaXia. |
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http://www.sadlerswells.com/whats_on/2003_2004/random.asp
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| | Ataxia - Wikipedia, the free encyclopedia |
| | People with ataxia experience a failure of muscle control in their arms and legs, resulting in a lack of balance and coordination or a disturbance of gait. | | | While the term ataxia is primarily used to describe this set of symptoms, it is sometimes also used to refer to a family of disorders. | | | Most disorders that result in ataxia cause cells in the part of the brain called the cerebellum to degenerate, or atrophy. |
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http://en.wikipedia.org/wiki/Ataxia
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| | The DRM WebWatcher: Ataxia |
| | FARA is a nonprofit organization that pursues educational, scientific and research activities leading to treatments for Friedreich's ataxia related ataxias. | | | In addition to subscription instructions, this nicely constructed web site includes "FAQs," useful tips based on personal experiences and ideas offered on the FAPG list, research notes, photos, and more. | | | Hereditary ataxia is a group of progressive, degenerative neurological disorders characterized by ataxia (incoordination). |
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http://www.disabilityresources.org/ATAXIA.html
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| | Friedreich's Ataxia |
| | When both parents are carriers, they have a one-in-four chance in each pregnancy of conceiving a child who will develop the disease. | | | muscle weakness and loss of coordination (ataxia) in the arms and legs | | | However, there are treatments for its cardiac symptoms and ways to manage ataxia and muscle weakness. |
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http://www.geocities.com/andysannex/fa.html
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| | Dr. Koop - Friedreich's Ataxia- Health Encyclopedia and Reference |
| | You should promptly seek professional medical care if you have any concern about your health, and you should always consult your physician before starting a fitness regimen. | | | However, many of the following symptoms associated with Friedreich's Ataxia can be treated or controlled. | | | What medications will be prescribed to treat some of the symptoms? |
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http://www.drkoop.com/encyclopedia/43/13.html
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| | Ataxia (Ataxia-telangiectasia) |
| | The word “ataxia” means lack of muscle control and “telangiectasia” means tiny, red spots, both of which characterize this disease. | | | Ataxia refers to a group of nervous system disorders marked by loss of muscle control. | | | While carriers will not show symptoms of ataxia, they may experience increased radiation sensitivity and higher cancer rates. |
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http://www.hmc.psu.edu/childrens/healthinfo/a/ataxia.htm
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| | ataxia : Definition |
| | Ataxia is the shaky and unsteady movements that result from the brain's failure to regulate the body's posture and the strength and direction of movements. | | | Ataxia is most often caused by disease activity in the cerebellum. | | | Search for ataxia in these other databases too |
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http://www.biology-text.com/definition.php?word=ataxia
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| | ataxia on Encyclopedia.com |
| | ATAXIA [ataxia], lack of coordination of the voluntary muscles resulting in irregular movements of the body. | | | Ataxia can be brought on by an injury, infection, or degenerative disease of the central nervous system, e.g., syphilis, encephalitis, brain tumor, or multiple sclerosis. | | | The term also designates a specific type of cerebral palsy. |
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http://encyclopedia.infonautics.com/html/a1/ataxia.asp
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| | Spinocerebellar ataxia |
| | The cerebellum is concerned with coordination of movements, so the "wasting away" of this critical control center results in a loss of muscle coordination. | | | Persons with spinocerebellar ataxia, of which there are several types, experience a degeneration of the spinal cord and the cerebellum, the small fissured mass at the base of the brain, behind the brain stem. | | | In this way, it is similar to fragile-X syndrome, Huntington disease and myotonic dystrophy, all of which exhibit a triplet repeat expansion of a gene. |
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http://www.ncbi.nlm.nih.gov/books/bv.fcgi?call=bv.View..ShowSection&rid=gnd.section.218
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| | Friedreich's ataxia |
| | "Spinocerebellar Degeneration (Friedreich's Ataxia)." In Harrison's Principles of Internal Medicine, ed. | | | Friedreich's ataxia is the most common inherited ataxia, affecting between 3,000-5,000 people in the United States. | | | Ataxia is a condition marked by impaired coordination. |
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http://www.lifesteps.com/gm/Atoz/ency/friedreichs_ataxia.jsp
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| | BBC NEWS Health Medical notes Cerebellar ataxia |
| | And, while it is not fatal in itself, it can place unbearable stress upon the heart. | | | The condition is named after the cerebellum in the brain | | | However, in some cases it is not known what causes the condition. |
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http://news.bbc.co.uk/1/hi/health/medical_notes/4055425.stm
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| | Ataxia Telangiectasia / Family Village Library |
| | These funds are then used to accelerate first-rate, international scientific research aimed at finding a cure and improving the lives of all children with Ataxia Telangiectasia. | | | This private, non-profit organization was founded in 1984 by Pam and George Smith, whose daughter Rebecca has A-T. The sole purpose of this foundation is to fund medical research that may lead to a cure for ataxia-telangiectasia. | | | This organization supports research that will contribute to a model of disease management for A-T, along the lines of those developed for diabetes, cystic fibrosis, PKU, epilepsy, and others. |
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http://www.familyvillage.wisc.edu/lib_attl.htm
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| | Episodic Ataxia |
| | If you experience any difficulties with this site, please email our | | | Affected patients also may have migraine; some even complain of basilar migraine. | | | Episodic ataxia, a disorder affecting the cerebellum, is a rare inherited syndrome of intermittent ataxia. |
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http://www.ucsf.edu/humgene/episodic_ataxia.htm
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| | OPCA Awareness Website -OLIVOPONTOCEREBELLAR ATROPHY ataxia, Spinocerebellar Ataxia, Cerebellar Ataxia |
| | Creating awareness for Olivopontocerebellar atrophy and other ataxias! | | | Olivopontocerebellar atrophy (OPCA) refers to a group of ataxias characterized by progressive neurological degeneration affecting the cerebellum, the pons and the inferior olives. | | | hereditary: olivopontocerebellar atrophy, spinocerebellar ataxia (SCA), SCA # "slow-eye movement" ataxia, Machado-Joseph disease, "pure" cerebellar ataxia, OPCA #, ataxia with ophthalmoplegia, ataxia with retinopathy, Marie's ataxia, Holmes ataxia, Menzel's ataxia, spinopontine atrophy, etc. |
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http://alyshia.com/OPCA
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| | Acute cerebellar ataxia Encyclopedia Search - Drug Price Search |
| | No treatment is generally attempted for acute cerebellar ataxia. | | | The diagnosis of acute cerebellar ataxia is made by excluding other causes of ataxia, and by taking a history of a recent illness. | | | Ataxia may affect movement of the trunk (axial) or limbs. |
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http://www.drug-price-search.com/encyclopedia/?encyclopedia_name_url=148&level=2
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| | Inclusive Technology - Useful Websites & Contacts - Ataxia |
| | Broadly speaking, the word "ataxia" simply means unsteadiness and clumsiness, and has been given to the condition because those are usually the earliest symptoms. | | | Ataxia deals with all kinds of degenerative cerebellar ataxia, not just Friedreich's ataxia, and funds research into causes and treatments. | | | This is because ataxia destroys both nerve and muscle cells. |
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http://www.inclusive.co.uk/support/ataxia.shtml
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| | :: CIRAH - Ataxia Clinic :: |
| | Ataxia definition: Friedreichs ataxia, ataxia telangiectasia, cerebellar ataxia, spinocerebellar ataxia, among others, are hereditary neurodegenerative disorders which can manifest in anyone and at any stage of a person's life. | | | Ataxia symptom is awkwardness, or loss of coordination. | | | The project is responsible for studying the illness and looking for a solution which will stop its progression both in people already showing signs of the illness, and for their descendents who will do it in the future. |
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http://www.ataxiacubana.sld.cu
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| | Friedreich ataxia - Genetics Home Reference |
| | Friedreich ataxia is a genetic condition that damages nerve tissue, causing a loss of muscle coordination (ataxia) that worsens over time. | | | You may also be interested in these resources, which are designed for healthcare professionals and researchers. | | | Certain nerve and muscle cells cannot function properly with a shortage of frataxin, leading to the signs and symptoms of Friedreich ataxia. |
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http://ghr.nlm.nih.gov/condition=friedreichataxia
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| | Ataxia Telangiectasia |
| | Individuals with AT also have an increased risk of developing certain malignancies, particularly of the lymphatic system (lymphomas), the blood-forming organs (e.g., leukemia), and the brain. | | | Ataxia telangiectasia (AT) is a complex genetic neurodegenerative disorder that may become apparent during infancy or early childhood. | | | Ataxia is often accompanied by difficulty speaking (dysarthria); drooling; and an impaired ability to coordinate certain eye movements (oculomotor apraxia), including the occurrence of involuntary, rapid, rhythmic motions (oscillations) of the eyes while attempting to focus upon certain objects (fixation nystagmus). |
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http://www.peacehealth.org/kbase/nord/nord406.htm
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| | Ataxia Telangiectasia |
| | Ataxia telangiectasia (A-T) is a rare, progressive, neurodegenerative childhood disease that affects the nervous system and other body systems. | | | The hallmarks of A-T are ataxia (lack of muscle control) and telangiectasias (tiny, red "spider" veins), which appear in the corners of the eyes or on the surface of the ears and cheeks soon after the onset of ataxia. | | | The first signs of the disease, which include lack of balance and slurred speech, usually occur during the first decade of life. |
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http://healthlink.mcw.edu/article/921385170.html
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| | Euro-Ataxia |
| | The researchers and research teams have always shown a exemplary behaviour in this. | | | All kind of research groups were hunting for the genes that caused hereditary diseases, including the hereditary ataxias. | | | Because genetic research is very expensive and the ataxias are rare disorders, it calls for international cooperation. |
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http://www.euro-ataxia.org
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| | BBC - Health - Conditions - Ataxia |
| | Spinocerebellar ataxia type 6 is thought to be the most common in the UK. | | | Ataxia can be caused by many things, including multiple sclerosis, brain tumours and alcoholism. | | | Symptoms generally start early in life but there are cases where symptoms start later on. |
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http://www.bbc.co.uk/health/conditions/ataxia1.shtml
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| | Ataxia - Telangiectasia |
| | Ataxia telangiectasia (AT) is a complex genetic disease characterized by: Progressive cerebellar degeneration leading to ataxia... | | | Ataxia telangiectasia (A-T) is a rare, recessive genetic disorder of childhood that occurs in about 1/40,000 and 1/100,000 persons worldwide. | | | Incidence of cancer in 161 families affected by Ataxia - Telangiectasia by Swift M., et al. |
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http://ibis-birthdefects.org/start/ataxsyn.htm
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| | International Ataxia Awareness Day |
| | “People with ataxia can have some odd symptoms and people are often misled and make assumptions. | | | Help more people understand the effects of ataxia | | | Help raise funds internationally for research into treatments for ataxia |
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http://www.ataxiaawarenessday.org
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| | Job Accommodation Network |
| | A majority of individuals with ataxia use mobilitiy aids and have difficulty with their speech, although mental abilities are unaffected. | | | Developing workplace strategies to deal with work problems before they arise, providing sensitivity training to coworkers, allowing telephone calls during work hours to doctors and others for support, and easy access to information on counseling and employee assistance programs are beneficial. | | | Friedreich's, the best known inherited ataxia, and other cerebellar ataxias are impairments of the nervous system, most of which are inherited. |
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http://www.jan.wvu.edu/soar/other/ataxia.html
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| | Ataxia-telangiectasia - Genetics Home Reference |
| | Ataxia-telangiectasia is a rare inherited disorder of childhood that affects the nervous system, immune system, and other body systems. | | | This disorder is characterized by progressive difficulty with coordinating movements (ataxia) beginning in early childhood. | | | Affected children typically develop difficulty walking, problems with balance, abnormal eye movements, and slurred speech. |
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http://ghr.nlm.nih.gov/condition=ataxiatelangiectasia
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| | Facts About Friedreich's Ataxia MDA Publications |
| | After doctors did some tests, I found out I had Friedreich’s ataxia. | | | MDA offers a great program of services, leads the world in Friedreich’s ataxia research and keeps us well informed about the disease. | | | Erin Kiernan, a teenager with Friedreich's Ataxia, monitors her cardiac function closely and gets help from several specialists. |
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http://www.mdausa.org/publications/fa-fried.html
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