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| | Antiviral drug - Wikipedia, the free encyclopedia |
 | | The first experimental antivirals were developed in the 1960s, mostly to deal with herpesviruses, and were found using traditional trial-and-error drug discovery methods. | | | This pocket is similar in most strains of rhinoviruses, and the drug also seems to work against enteroviruses, which can cause diarrhea, meningitis, conjunctivitis, and encephalitis. | | | All drugs designed to fight pathogens have a common problem: over the long run, the pathogens evolve to acquire resistance to the drugs. |
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http://en.wikipedia.org/wiki/Antiviral_drug
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| | Chemical properties of the antiviral drug Acyclvoir: Always-Health.com |
| | This drug is used for the treatment of sexually transmitted diseases including genital herpes. | | | It has been nearly quarter of a century since the antiviral drug Acyclovir was first approved and brought into the market as one of the most effective antiviral drugs for the treatment of genital herpes. | | | In turn, this necessitated the need for larger and continuous forms of drug therapy, which is not expensive for the average patient, the duration too may become a problem. |
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http://www.always-health.com/Acyclovir2.html
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| | Antiviral drug used to treat AIDS to be tested as vaccine |
| | Antiviral drug used to treat AIDS to be tested as vaccine | | | A theory that an antiviral drug used to treat AIDS may also be used to prevent it will be put to the test in San Francisco and Atlanta this month, when enrollment of 400 gay men will begin for the U.S. arm of an international HIV prevention study. |
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http://www.sfgate.com/cgi-bin/article.cgi?file=/chronicle/archive/2004/12/01/MNGRMA48351.DTL
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| | Influenza Antiviral Drugs and Related Information |
| | Use of antiviral drugs does not eliminate the risk of complications, and some complications (as well as other medical conditions that could be confused with influenza) can be life-threatening. | | | Recent increases in the number and promotion of antiviral drugs for influenza have increased interest in the role of specific antiviral drugs for this condition. | | | FDA encourages reporting of serious adverse events (associated with these or any other drugs) to the MedWatch program to facilitate continued updating of risk/benefit information. |
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http://www.fda.gov/cder/drug/antivirals/influenza
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| | [No title] |
| | Other antiviral drugs currently on the market are active only against type A. "These results are very encouraging, but it is important to bear in mind that these studies were done in experimentally infected volunteers," said Dr. Frederick Hayden, head of the study at U.Va. and professor of internal medicine. | | | Researchers here and at the University of Rochester medical schools found that intranasal administration of the experimental drug was 82 percent effective in preventing laboratory evidence of infection and 95 percent effective in preventing the fever associated with experimental influenza. | | | The study of delayed treatment was too small to be conclusive at this point. |
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http://www.virginia.edu/insideuva/textonlyarchive/96-01-26/1.txt
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| | Genital Herpes Transmission Reduced With Antiviral Drug |
| | The findings that antiviral therapy reduces HSV-2 transmission add an important option in the management of patients with genital herpes who are sexually active, said Wald, medical director of the UW Virology Research Clinic. | | | In the last few years, Wald, Corey and others have shown that such drugs also reduce the frequency and amount of HSV-2 that is shed from the genital area, which is the major source of herpes transmission. |
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http://www.altpenis.com/penis_news/20031131232646data_trunc_sys.shtml
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| | Apath,LLC Drug Discovery |
| | The worldwide market for antiviral drugs is estimated to be approximately $10 billion and it is expected to grow rapidly as new therapies become available. | | | Most of these drugs, however, are for treatment of human immunodeficiency virus (HIV) and various herpesviruses. | | | Similar to HIV, HCV has a high predeliction to develop resistance to antiviral drugs during therapy. |
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http://www.apath.com/Directory/Antiviral_Drug_Discovery/Drug_Discovery.asp
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| | Journals Antiviral Therapy Home |
| | The field of antiviral therapy is expanding at an unprecedented rate. | | | Previously, however, publications concerning clinical aspects of antiviral therapy have been dispersed among a wide range of different journals, making it increasingly difficult to keep abreast of this multidisciplinary field. | | | Antiviral Therapy is an official publication of the International Society for Antiviral Research |
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http://www.intmedpress.com/General/showSectionSub.cfm?SectionID=2&SectionSubID=1&SectionSubSubID=1
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| | Antiviral Drug Sharply Reduces Return of Herpes of the Eye [NEI News and Events] |
| | Researchers have found that an antiviral drug, often used to suppress genital herpes, also decreases the recurrence of herpes of the eye. | | | "This drug is the first treatment that helps prevent herpes of the eye from returning," said Dr. Carl Kupfer, director of the National Eye Institute (NEI), part of the Federal government’s National Institutes of Health (NIH) and the agency that supported the clinical trial. | | | Antiviral Drug Sharply Reduces Return of Herpes of the Eye |
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http://www.nei.nih.gov/news/pressreleases/hedsii.asp
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| | Interactions of the Valtrex antiviral drug: Always-Health.com |
| | In discussing the side effects of Valtrex antiviral drug generally prescribed for the treatment of various types of herpes, it was found that though there exists little evidence to show that any evaluation of pregnant women was ever carried out with respect to the use of Valtrex antiviral drug. | | | Thus, studies carried out on the Valtrex antiviral drug show that it has no depletion or interference action, side effects are present as with all antiviral drugs, absence of any supportive interaction, and evidence of an adverse interactions. | | | Properties of the Valtrex drug and its application |
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http://www.always-health.com/Valtrex2.html
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| | Introduction — Fourth HIV DRP Symposium: Antiviral Drug Resistance |
| | The Symposium on Antiviral Drug Resistance brings together researchers in a variety of virus systems who share common interests in understanding the mechanism of action of the viral targets for resistance, the mechanism of antiviral therapy, and the mechanism of resistance to specific therapy. | | | The problem of resistance to antiviral therapy is not limited to HIV, but has been seen in all viruses against which antiviral therapy has been developed. | | | This problem not only results in the frequent failure of therapy, but limits the effectiveness of subsequent therapies. |
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http://www.ncifcrf.gov/campus/symposium/introduction.html
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| | Antiviral drug resistance |
| | Amantadine and its structural homologue rimantadine are currently the only drugs available to treat influenza A infection; on the basis of their prophylactic and therapeutic efficacy they are an acceptable alternative to vaccine. | | | The use of an antiviral drug will provide a selective pressure for the preferential growth of variants with a reduced susceptibility to drugs in accordance with Darwinian evolutionary principles. | | | Finally, there is an urgent need to clarify the most effective use of antiviral resistance assays in clinical practice. |
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http://bmj.bmjjournals.com/content/vol317/issue7159/fulltext/supplemental/660/index.shtml
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| | Division of Antiviral Drug Products - Emerging Viral Infections |
| | Sponsors seeking to develop antiviral drugs for emerging infections are urged to communicate with the Division as early in the development process as possible. | | | For some drug development programs for emerging infections, repeated Pre-IND interactions may be desirable. | | | Sponsors are urged to contact DAVDP early in the development process to discuss the most efficient design and potential uses of nonclinical as well as clinical studies. |
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http://www.fda.gov/cder/ode4/preind/emerging.htm
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| | Antivirals targeting the conserved cis-acting sequences of RNA viruses |
| | A major problem with current antiviral drugs is the high frequencies of drug-resistant mutants. | | | How antiviral drugs are best developed is not so clear. | | | Public health measures are arguably the single most important factor contributing to the improved health and increased longevity of humans. |
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http://www.microbiology.wustl.edu/dept/fac/huang/ccas/intro.html
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| | Antiviral Drug More Effective Than Cesarean in Preventing Neonatal Herpes |
| | SAN FRANCISCO, Oct. 16, 1996 -- A common antiviral drug taken during the last month of pregnancy is more cost-effective and prevents more neonatal infections than cesarean delivery for women with genital herpes, according to a UCSF analysis published in the current (October) issue of the journal Obstetrics and Gynecology. | | | Antiviral Drug More Effective Than Cesarean in Preventing Neonatal Herpes | | | If you have any technical questions or other concerns about this site, feel free to contact us at webmaster@docguide.com. |
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http://pslgroup.com/dg/cff6.htm
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| | Incremental progress with new antiviral drug |
| | Donor-to-donor PBMC variations (variations among study subjects) in host co-receptor expression did not affect potency in the study discussed in abstract H-875, indicating that “427” should be active regardless of individual variations in CCR5 expression or function. | | | No clinically significant increases in any laboratory safety tests including haematology, clinical chemistry or lipid profiles, and no clinically significant changes in 12-lead ECGs, blood pressure, or heart rate were observed. | | | These subjects had been failing T-20 for a median time of 66 weeks (range 28-165). |
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http://www.i-base.org.uk/pub/htb/v4/htb4-9/Incremental.html
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| | The Body: The Buzz: Taking Giant Steps Forward in Antiviral Drug Treatment |
| | This has eventually translated into applying the results in the clinics with their patients. | | | Highly experienced patients can be hopeful because they have new sophisticated options with further upcoming choices that are approaching in the near future. | | | The Body: The Buzz: Taking Giant Steps Forward in Antiviral Drug Treatment |
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http://www.thebody.com/tpan/janfeb_04/buzz.html
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| | China Vows to End Misuse of Antiviral Drug |
| | The report didn't say when or how widely the drug amantadine was misused or whether farmers still use it. | | | "This is a matter of concern if these studies are proven to be correct and this drug is not useful in the fight against H5N1 in humans," Wadia said. | | | "What we can say in general is that any misuse of drugs, and especially antivirals which are key in the fight against pandemics... |
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http://sfgate.com/cgi-bin/article.cgi?f=/n/a/2005/06/20/international/i193200D04.DTL
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| | antiviral drug on Encyclopedia.com |
| | Acyclovir is also used to lessen the pain and speed the healing of herpes zoster (shingles). | | | Landmark Study Demonstrates Comparable Antiviral Efficacy of HIV Drugs VIRAMUNE(R) and Efavirenz Over 48 Weeks; Study Also Finds VIRAMUNE-Based Therapy Results in Improved Lipid Profile. | | | Fomivirsen, which is an antisense drug, is also used to treat CMV. |
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http://www.encyclopedia.com/html/a1/antivir.asp
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| | New Studies May Knock Antiviral Drug Off the Fast Track |
| | The latest studies, however, did not produce clear-cut evidence that the drug was effective. | | | And two other studies showed it couldn't help most patients shake the telltale headaches of viral meningitis, an infection of the lining of the brain or spinal cord. | | | In one report, researchers say the drug couldn't significantly shorten the time patients battled a severe cold. |
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http://my.webmd.com/content/article/23/1728_56519
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| | Division of Antiviral Drug Products - ODE IV Pre-IND Consultation Program |
| | We encourage all potential drug sponsors or investigators to examine the information available from this site and to initiate contact with us as early in the drug development process as possible, so that they will have the opportunity to consider our recommendations in planning preclinical and clinical development programs. | | | The Division of Antiviral Drug Products (DAVDP) is responsible for: | | | The Division of Anti-Infective Drug Products (DAIDP) is responsible for: |
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http://www.fda.gov/cder/ode4/preind
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| | ALIFE VI abstract: Computational Coevolution of Antiviral Drug Resistance |
| | An understanding of antiviral drug resistance is important in the design of effective drugs. | | | We use this method to characterize general features of inhibitors that are effective in overcoming resistance, and to study related issues of selection pathways, cross-resistance, and combination therapies. | | | Comprehensive features of the interaction between drug designs and resistance mutations are difficult to study experimentally, because of the very large numbers of drugs and mutants involved. |
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http://alife6.alife.org/abstracts/BR71.html
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| | DAYBREAK - Antiviral Drug Resistance Predictions Now Possible |
| | The model, reported in the June 1 issue of Nature Medicine and lauded in an accompanying review by a Yale School of Management professor of management sciences and medicine, looked specifically at the likelihood of drug resistance occurring with increased use of a drug to treat genital herpes. | | | "The methodology we've developed and applied to genital herpes can be used as a health policy tool to predict the likelihood of future levels of antibiotic or antiviral resistance for numerous infectious diseases, including HIV," said Blower. | | | Researchers led by a UCSF scientist have developed a model for predicting the emergence of antiviral drug resistance and for identifying the key factors that generate drug resistance. |
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http://www.ucsf.edu/daybreak/1998/06/02_anti.html
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| | Panavir ® - the Russian antiviral drug |
| | The instruction on medical application of the drug Panavir | | | REPORT on clinical approbation of viricide PANAVIR (1st phase) | | | Interaction of the drug with other medicinal preparations is not detected. |
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http://panavir.com/info
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| | Vidyya Medical News Service - Today in Vidyya |
| | All of these drugs require a prescription from a doctor. | | | For more detailed information, contact a physician or consult the package insert that comes with the medication. | | | This drug is inhaled and can cause side effects, especially in those with asthma or other chronic lung disease. |
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http://www.vidyya.com/vol5/v5i341_4.htm
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| | Antiviral drug discovery and clinical trials: News from Lab21 |
| | Antiviral drug discovery and clinical trials: News from Lab21 | | | 'Our customers can benefit today from a unique portfolio of tests that allow the characterisation of a virus, the assessment of prospective drug candidates, and the understanding of potential resistance. | | | And once a drug is in the clinic, Lab21 offers pharmacogenetic testing and trial stratification, FDA requirements for registration, efficacy studies and resistance monitoring. |
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http://www.laboratorytalk.com/news/lav/lav100.html
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| | The Implications of Antibiotic and Antiviral Drug Resistance for the Power of Darwinian Evolution |
| | Unfortunately, this fact has made HIV quite difficult to combat, and many have suffered greatly because of difficulties in stopping HIV from becoming resistant to drugs. | | | If evolution ever had a chance, it had it's easiest and simplest chance with HIV virus anti resistance (see HIV Resistance to Antiretroviral Drugs (Journal of American Medical Association, Vol. | | | The second type is “antiviral drug resistance,” occurring when a virus mutates such that antiviral drugs are no longer effective in stopping the spread of a virus. |
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http://www-acs.ucsd.edu/~idea/antibiotic.htm
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| | The NCI's AIDS antiviral drug screening program. |
| | Yang SS; Antiviral Evaluation Branch, National Cancer Institute, Bethesda,; MD 20892, USA. | | | This communication will concentrate on the developmental therapeutic program on anti-AIDS drug discovery. | | | Keywords: Acquired Immunodeficiency Syndrome/*DRUG THERAPY Antiviral Agents/*TOXICITY Cell Fusion Cell Survival/DRUG EFFECTS Drug Screening/*METHODS Human HIV/*DRUG EFFECTS HIV Infections/*DRUG THERAPY HIV-1/*DRUG EFFECTS/PHYSIOLOGY *National Institutes of Health (U.S.) United States Virus Replication/DRUG EFFECTS JOURNAL ARTICLE |
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http://www.aegis.com/aidsline/1996/feb/M9620354.html
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| | SARS Information For Antiviral Drug Design Released By Protein Data Bank |
| | "Structure-based drug design has had an important impact on the development of anti-AIDS drugs that are now in use, and the rapid progress with characterizing the SARS coronavirus will enable more efficient paths to developing drugs for treating SARS. | | | As a tool to help unlock the secrets of biological systems in medical and pharmaceutical research, the PDB is a critical asset to 21st century genomic research and drug design. | | | Its availability to medical researchers worldwide is crucial because this enzyme is considered the primary target for new antiviral drugs being developed to combat the virus. |
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http://www.sciencedaily.com/releases/2003/07/030731081515.htm
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| | Truvada |
| | To learn more about how this once-a-day HIV treatment is used, click here. | | | Should only be taken in combination with other drugs for HIV | | | Truvada is an anti-HIV drug in the nucleoside reverse transcriptase inhibitor (NRTI or "nuke") family and is always given in combination with other anti-HIV drugs. |
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http://www.JustOnceADay.com
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| | New antiviral drug cuts flu's lifespan |
| | Any patients who experience such spasms should stop taking the drug and call their doctor. | | | For patients who have a chronic breathing condition, such as asthma or chronic obstructive pulmonary disease, the drug has not been shown effective and may carry risk, notes the FDA. | | | Anyone with an underlying respiratory disease is advised to have a bronchodilator readily available when they are taking the drug. |
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http://www.th-record.com/1999/07/28/fluspray.htm
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| | Panavir ® - the Russian antiviral drug |
| | For the present the drug has no analogues in the world and is successfully applied where usual antiviral drugs does not cure: chronic tick-borne encephalitis, recurrent genital herpes, Human Papilloma Virus (HPV), Epstein-Barr Virus. | | | * The Study of antiviral drug Panavir for herpes viral infection in vitro culture (Scientific Research Institute of virology, RAMS). | | | * The study of antiviral activity of the drug Panavir at experimental infection caused by hepatitis C virus in cell cultures. |
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http://panavir.com
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| | Amazon.ca: Books: Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats |
| | Antiviral Drug Discovery gives readers a cutting-edge view of how chemical concepts are being mobilized to develop novel approaches that will effectively confront emerging diseases and biowarfare. | | | Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats | | | Look for books like Antiviral Drug Discovery for Emerging Diseases and Bioterrorism Threats by subject: |
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http://www.amazon.ca/exec/obidos/ASIN/0471668273
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| | Stability and release of antiviral drug from EVA copolymer |
| | The study utilizes an oral biocompatible material based on ethylene vinyl acetate copolymer (EVA) designed to release drugs in vitro at therapeutic levels over several days. | | | Conclusions: It seems clear that among several factors, the dissolution of drug in the polymer matrix and the rate at which the drug molecules diffuse, influence drug release process. | | | The “burst” effects may be attributed to the rate of dissolution of drug molecules in EVA and the rate of diffusion of drug molecules through the matrix. |
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http://iadr.confex.com/iadr/2005Balt/techprogram/abstract_60192.htm
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| | Antiviral Drug May Be Effective Against Smallpox |
| | There also is great promise in the area of antiviral drugs, Fauci said. | | | But all doctors have to offer smallpox patients are therapies to help keep them alive, not fight the virus. | | | WASHINGTON -- While the government tries to ramp up production of smallpox vaccine, scientists are hopeful that an antiviral drug that is already on the market might prove to be the first effective treatment for the disease. |
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http://www.freerepublic.com/focus/fr/554234/posts
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| | American Family Physician: Antiviral drug therapy.@ HighBeam Research |
| | American Family Physician: Antiviral drug therapy.@ HighBeam Research | | | Amantadine, used in the treatment of Parkinson's disease, was initially used to prevent or reduce the severity of influenza. | | | American Family Physician; 1/1/1991; Goodpasture, Hewitt C. In the past 20 years major advances have been made in the development of antiviral agents that may some day make viruses as treatable as bacteria. |
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http://highbeam.com/library/doc0.asp?DOCID=1G1:10365385&...
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| | BBC NEWS Business Bird flu drug sales boost Roche |
| | During the third quarter Roche said it also benefited from strong sales of its anti-cancer treatments, with sales of anti-cancer drug Avastin doubling to 486m francs. | | | Roche's Tamiflu drug is seen as the most effective treatment for the most dangerous strain of bird flu, which killed 60 people in Asia in 2003, but it is not a vaccine. | | | Drugs firm Roche has seen third-quarter revenues rise 17% helped by a jump in sales of Tamiflu, which is seen as the best treatment for bird flu. |
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http://news.bbc.co.uk/2/hi/business/4355636.stm
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| | HIVDrugResistance.com - A site for the HIV community |
| | If you or someone you care about is living with HIV, you need to know what HIV drug resistance is, how it's measured and how it affects treatment. | | | Is an HIV drug resistance test right for you? | | | Has your healthcare provider previously used an HIV drug resistance test as part of your treatment planning? |
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http://www.HIVDrugResistance.com
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| | Antiviral Agents Bulletin Home Page |
| | The Bulletin covered all antiviral therapeutics, but the largest portion of news articles, patents, etc., concern HIV/AIDS-related antiviral drugs and vaccines. | | | For 15 years (3/1988-3/2003), the Antiviral Agents Bulletin was the only periodical specializing in antiviral drug and vaccine development. | | | Articles in the Antiviral Agents Bulletin described and assessed commercial and scientific developments, treatment advances and trends, patents and technology transfers, federal and regulatory activities, and information resources. |
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http://www.bioinfo.com/antiviral.html
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| | ABC News: WHO Questions Misused Antiviral Drug |
| | "This is a matter of concern if these studies are proven to be correct and this drug is not useful in the fight against H5N1 in humans," Wadia said. | | | WHO Seeks Information From China After Report of Misused Antiviral Drug | | | Health experts worry that bird flu might mutate into a form that can spread directly from person to person, setting off a pandemic that could claim millions of lives. |
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http://abcnews.go.com/Health/wireStory?id=865253
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| | Scientific Program — Fifth HIV DRP Symposium: Antiviral Drug Resistance |
| | Scientific Program — Fifth HIV DRP Symposium: Antiviral Drug Resistance | | | Present address: Laboratory of Molecular Virology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland | | | Further, these results demonstrate that infection with the PPTSUB virus results in a dramatic increase in 2-LTR circle formation, possibly reflecting a reduction in the fraction of proviral DNA which is integrated. |
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http://web.ncifcrf.gov/campus/symposium/abstract58_2004.html
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| | Antiviral drug : Antiviral |
| | drug : Antiviral article @ Euro Online Encyclopedia'>Antiviral drug : Antiviral | | | It uses material from the wikipedia article Antiviral drug : Antiviral. | | | drug : Antiviral article @ Euro Online Encyclopedia'>Antiviral drug : Antiviral
article at Free Euro Online Encyclopedia | |
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http://www.eurofreehost.com/an/Antiviral_6.html
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