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| | Pseudonaja affinis (PIM 450) |
 | | Following antivenom therapy there is a possibility that the patient may develop serum sickness. | | | Specific treatment If there is evidence of systemic envenomation, antivenom therapy is the most important treatment. | | | This ignores the danger of coagulopathy, best managed by antivenom therapy, and the fact that early antivenom therapy may avoid severe paralysis and the hazards of artificial ventilation. |
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http://www.intox.org/databank/documents/animal/pseunaja/pseunaja.htm
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| | BestBETs: Scorpion envenomation: Does antivenom reduce serum... |
| | Efficacy of antivenom therapy for neutralizing circulating venom antigens in patients stung by Tityus serrulatus scorpions. | | | Evaluation of antivenom therapy in children severely envenomed by Androctonus australis garzonii (Aag) and Buthus occitans tunetanus (Bot) scorpions. | | | Two studies documented clinical improvements with antivenom treatment. |
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http://www.bestbets.org/cgi-bin/bets.pl?record=00796
(489 words)
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| | Template |
| | For this reason it is advisable to give adrenaline with the antivenom, and all patients being treated with antivenom must be monitored carefully. | | | This suggests that human immunoglobulin antivenom may be possible in the future. | | | At the moment however, no such antivenom exists. |
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http://www.portfolio.mvm.ed.ac.uk/studentwebs/session3/68/antivenom.html
(821 words)
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| | Antivenom immunesera - Patent 6833131 |
| | Conventional polyspecific antivenoms, however, lack the specifity of monospecific antivenoms and are, therefore, less effective in neutralising the pharmacological activity of a venom. | | | The antisera which comprise the antivenom may be whole antisera. | | | According to a fifth aspect of the present invention there is provided a kit for administering antivenom to a human or animal body comprising: |
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http://www.freepatentsonline.com/6833131.html
(4201 words)
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| | Gaboon Viper (Bitis gabonica) |
| | As soon as the patient is stabilized, continue the antivenom infusion at a slower rate. | | | Assuming the patient's condition is stable, wait 15-30 minutes before administering the antivenom. | | | IF SIGNIFICANT SYSTEMIC SIGNS OR SYMPTOMS become apparent, begin antivenom therapy as follows: |
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http://www-surgery.ucsd.edu/ent/davidson/Snake/Gabonica.htm
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| | eMJA: Antivenom dosing in 35 patients with severe brown snake (Pseudonaja) envenoming in Western Australia over 10 years |
| | Theakston RD. An objective approach to antivenom therapy and assessment of first-aid measures in snake bite. | | | There may have been variations in practice and we were unable to analyse the influence of factors such as the use of exogenous coagulation factors, sampling times for coagulation studies and clinical end-points used to determine when circulating venom was neutralised. | | | The use of a pressure-immobilisation bandage was documented in the notes of 34 of the 35 patients; however, immediate application of a pressure-immobilisation bandage was documented for only six patients (17%). |
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http://www.mja.com.au/public/issues/181_11_061204/yeu10307_fm.html
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| | Spiders - Funnel-web Spider antivenom |
| | An antivenom for the Sydney Funnel-web Spider was first developed for clinical use in 1981 By Dr Struan Sutherland and his team at the Commonwealth Serum Laboratories. | | | At the same time Sutherland experimentally established the effectiveness of the compression/immobilisation first aid technique for funnel-web bite. | | | This antivenom has also been effective against other dangerous funnel-web spider species. |
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http://www.amonline.net.au/spiders/dangerous/funnelweb/antivenom.htm
(99 words)
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| | Antivenom Research |
| | Skin testing with antivenom for allergy to antivenom is unreliable and waste of time. | | | It may also assist the development of desensitising therapy for herpetologists, many of whom suffer from potentially lethal allergy to snakes and their venom. | | | An antihistamine may also be given parenterally, bearing in mind it may have sedatory effects and may also cause hypotension. |
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http://www.kingsnake.com/toxinology/antivenom.html
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| | eMJA: Antivenom efficacy, safety and availability: measuring smoke |
| | This study is in contrast to a previous study from Brazil that failed to demonstrate any difference in early antivenom reactions with prophylactic promethazine alone. | | | 4 However, the recent WHO workshop called for a re-examination of old assumptions concerning such reactions and, consequently, what constitutes “best practice” for antivenom manufacture and administration. | | | Serum reactions: an analysis of commercial antivenoms and the possible role of anticomplementary activity in de-novo reactions to antivenoms and antitoxins. |
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http://www.mja.com.au/public/issues/180_01_050104/che10701_fm-2.html
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| | eMedicine - Snake Envenomations, Coral : Article by Robert Norris, MD |
| | The doctor should leave the bandages and splint in position until he or she has assembled appropriate antivenom and drugs that may need to be used when the dressings and splint are removed. | | | Also effective in oral form for treating itching associated with serum sickness. | | | If acute reaction occurs, antivenom should be halted and the patient treated prn with epinephrine, antihistamines, and steroids. |
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http://www.emedicine.com/emerg/topic542.htm
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| | Airline escorted by F16 to IAH airport Houston TX |
| | Stay tuned to khou.com and Channel 11 for more information on this incident. | | | Navigation: use the links below to view more comments. | | | I think this is a different incident than the one you have linked to. |
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http://www.freerepublic.com/focus/news/748831/posts
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| | New Antivenom For Snake Bites |
| | The researchers state all the patients studied improved during a four-hour period, despite a worsening of their condition just before they received the antivenom. | | | The researchers note that current antivenom treatment is ineffective against nervous system poisoning caused by crotalid snake bite, but "this new therapy shows promise in the reversal of neurotoxicity." | | | The Fab antivenom is effective against the most common of these, which are caused by the crotalid family of pit vipers -- copperheads, cottonmouth water moccasin, and about 30 different species of rattlesnake (including the North American and Western diamondback). |
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http://www.personalmd.com/news/a1997070405.shtml
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| | British Journal of Pharmacology - The effects of specific antibody fragments on the 'irreversible' neurotoxicity ... |
| | The new Fab based antivenom was found to be 8.5 times more effective in vivo and more than twice as effective in vitro compared to the current clinical treatment (CSL F(ab') | | | antivenom resulted in a 40−50% blockade of the response which was reversed by washing. | | | This reversal could also be demonstrated following the late addition of antivenom, an important factor in effective snake bite therapy. |
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http://www.nature.com/bjp/journal/v126/n3/full/0702286a.html
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| | Position Statement |
| | Decisions regarding which antivenom to obtain and in what amounts should be made by the physician or clinical toxicologist identified below. | | | The facility should have the capability to properly care for any possible adverse reactions to envenomation or treatment with antivenom. | | | When only non-FDA approved species-specific antivenom(s) are available, it is the responsibility of the institution to obtain an importation permit and FDA investigational new drug (IND) application for appropriate antivenom. |
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http://www.ijmt.net/ijmt/5_3/5_3_23.htm
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| | AM - Australia must help neighbours combat snakebite deaths: Antivenom Expert |
| | About 70 per cent of those need antivenom therapy and he says, many don't receive it. | | | KIEN XUAN TRINH: We don't have enough funding to increase, to develop number of antivenom for my patient. | | | JOSIE TAYLOR: And Dr Winkel says most people who fall victim to snakebites are those who are least likely able to afford antivenom treatment or even travel to a hospital. |
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http://www.abc.net.au/am/content/2003/s945282.htm
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| | Developing the Equations |
| | Our development of the equations you will need, in order to model the behavior of venom and/or antivenom in the human body, will be quick and dirty, but also relatively straight-forward. | | | Believe it or not, but the way in which venom and antivenom interact with receptor sites on the diaphragm muscle may be modeled as a catalytic reaction. | | | The development is similar for the other relevant concentrations for antivenom and venom-antivenom product in the blood, C |
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http://www.engin.umich.edu/dept/che/OldFiles/kinetics/web_mod/cobra/develop.htm
(268 words)
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| | Snake Antivenom |
| | Antivenins effective against only one given species are classified as "Monovalent" whereby antivenins effective against a broad range of species are classified as "Polyvalent". | | | Venomous snake bites may be treated with Antivenom. | | | Even though the antivenins are purified by multiple processes, it may contain other serum proteins and some individuals may have an extreme hypersensitive reaction to the injection and is only administered exercising caution. |
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http://www.tigerhomes.org/animal/snake-antivenom.cfm
(751 words)
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| | APPGuide Online - Consumer Medicine Information - DEATH ADDER ANTIVENOM - CMI |
| | APPGuide Online - Consumer Medicine Information - DEATH ADDER ANTIVENOM - CMI | | | As there are sometimes unpleasant and dangerous reactions to the antivenom (see Side Effects Of Death Adder Antivenom), it should not be given to people who have no effects from the bite. | | | The antivenom is purified and made into an injection for those people who may need it after being bitten by a death adder. |
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http://www.appco.com.au/appguide/drug.asp?drug_id=00098865&t=cmi
(634 words)
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| | SCORPION ENVENOMATION IN CHILDREN |
| | The treatment of scorpion envenomation consists of nonspecific or supportive care and specific treatment with scorpion antivenom, which should be species-specific. | | | reported that 58% of patients treated with antivenom had a delayed onset of rash or symptoms of serum sickness, and states that the use of antivenom for the less severe envenomation may subject them to unjustified risk. | | | With regards to treatment of completely asymptomatic cases, which in our series were 201, of which 182 (90%) could not be given any serum, these patients did not develop any symptoms and were discharged home in good condition after 24 hours of observation. |
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http://www.kfshrc.edu.sa/annals/195/98-189.html
(1762 words)
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| | NATURE. Australia's Little Assassins. Venom Rx PBS |
| | Venom may be deadly, but it can also be the source of medical cures. | | | Antivenom isn't the only medical use of venom. | | | Researchers also study venom because it contains dozens of substances that may be of medicinal value. |
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http://www.pbs.org/wnet/nature/australia/rx.html
(336 words)
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| | Rocky Mountain Poison and Drug Center |
| | Certainly the possibility exists to reduce the morbidity associated with inadequate dosing of antivenom and misguided fasciotomies for the treatment of crotalidae envenomations. | | | Patients presenting with milder symptoms, or those bitten by Akistrodon contortrix (copperhead) who would have previously gone untreated, may become acceptable candidates for therapy with a safer antivenom. | | | Based on experience from clinical trials, 4 to 6 vials are recommended as a starting dose to achieve "initial control". |
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http://www.rmpdc.org/crofab/index.cfm
(450 words)
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| | WHO Animal sera |
| | Antivenom therapy is key to the medical management of snakebite and other venomous bites and stings. | | | Unfortunately there are a number a problems for developing countries in accessing and using antivenoms. | | | The collaboration of manufacturers and regulatory bodies worldwide is needed in order to assure the availability of safe and effective antivenoms, particularly to those in developing countries. |
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http://www.who.int/bloodproducts/animal_sera/en
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| | Mechanism of Antivenom |
| | Careful execution of the injection of the antivenom is necessary to avoid any complications that may result from improper treatment. | | | The authors made the decision to use antivenom rather than antivenin, because this is a non-technical presentation, and the average person is more familiar with the word antivenom. | | | The spent antivenom and the neutralized venom are then excreted from the body. |
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http://www.engin.umich.edu/~cre/web_mod/cobra/avenom.htm
(375 words)
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| | Information on the Use of Antivenoms |
| | Antivenoms produced by a foreign manufacturer not licensed by the U. are considered experimental drugs, and the Department of Health and Human Service requires an Investigational New Drug filing to permit their importation. | | | A Statement of Investigator (Form FDA 1572) must accompany this statement for your new BB-IND or when there is a change. | | | Finally, it is important to remember that, in the event any foreign antivenom is used clinically, a complete case report must be submitted to the Center for Biologics Evaluation and Research. |
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http://www.fda.gov/Cber/ind/antiven.htm
(698 words)
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| | Find antivenom international for bites and stings - phones and links |
| | Universal Antivenom Project of the IMVS, a major medical and veterinary science R & D organisation in Australia, Institute of Medical & Veterinary Science (IMVS), and Veterinary Science Division (VSD - Gilles Plains) | | | Design of techniques and facilities to manufacture effective, inexpensive antivenoms The EPSRC and BBSRC are jointly funding a project under the Innovative Manufacturing Initiative (IMI) for the design of techniques and facilities to manufacture effective, inexpensive antivenoms. | | | produces antivenom for the treatment of snake, scorpion and spider bites. |
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http://globalcrisis.info/latestantivenom.htm
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| | The Columbian: Antivenom stock goes up@ HighBeam Research |
| | Search for more information on HighBeam Research for. | | | Hospitals hope the increase will replenish their supplies of the serum, depleted after the original antivenom manufacturer stopped making the product. | | | The Columbian: Antivenom stock goes up@ HighBeam Research |
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http://www.highbeam.com/library/doc0.asp?DOCID=1P1:86169284&refid=holomed_1
(198 words)
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| | SCORPION ANTIVENOM |
| | Stings by other scorpions, and many parabuthus stings, have only a slight effect, and the symptoms produced can often be alleviated without recourse to antivenom. | | | Can prevent symptoms and reduce pain if injected with the least possible delay. | | | Cold compresses and a local anaesthetic injected at the site of the sting may relieve pain. |
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http://home.intekom.com/pharm/saimr/scorpion.html
(385 words)
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| | Development of an Irukandji Jellyfish Antivenom |
| | The plan is to test the effectiveness of this antivenom against C. | | | The world’s only commercially available jellyfish antivenom is that made by CSL Limited (in Victoria) to combat the venom of the box jellyfish, Chironex fleckeri. | | | So far its efficacy has been assessed against only jimble venom. |
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http://www.hermonslade.org.au/projects/HSF_97_1/hsf_97_1.htm
(888 words)
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| | National Guard Health Affairs :: Antivenom |
| | In addition to the main plant the Center has several other laboratories for research and development, quality control, venom treatment and fractionation. | | | The Center’s being a producer of a very potent antivenoms against the venoms of local snakes and scorpions has its ultra modern plant for plasma processing and ampoule filling. | | | Antivenom against ALL Saudi venomous snakes and all of the highly dangerous Saudi scorpions are prepared from immune sera raised mainly in horses. |
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http://www.ngha.med.sa/Abount-NGHA/Centers-noHP/Antivenom
(235 words)
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| | Forum Message: 'Q: antivenom ?' |
| | We'll bring you back to this forum when you're done. | | | I was just curious how long after receiving a snakebite that is poisonous should you be givin antivenom? |
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http://www.practical-pet-care.com/snake_question.php?ID=1.465872345
(237 words)
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| | LS1TECH - View Profile: Antivenom |
| | Antivenom is not a member of any public groups | | | Contact Us - LS1TECH - Archive - Top |
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http://www.ls1tech.com/forums/member.php?u=4362
(17 words)
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| | Antivenom handbook eBook |
| | Including first aid and species information and pictures. | | | Information about use of CSL antivenoms for spider, snake and jelly fish bites. |
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http://www.memoware.com/?screen=doc_detail&doc_id=13417&p=category^!Medicine~!
(69 words)
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