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Topic: Antiemetic



  
 Advances in antiemetic pharmacology
With the clinical succes of ondansetron, much of the recent research involving antiemetics has focused on the development of other 5-HT -antagonists which might be effective antiemetics.
We studied the antiemetic effect of dexamethasone in a prospective, double-blind, placebo-controlled, randomized study in females who underwent general anesthesia for major gynecological surgery and used a IV-PCA with morphine in the postoperative period.
Unless NK -antagonist have multiple sites of action, the most economical explanation of their efficacy is that there is a common, NK receptor-mediated link in the reflex pathway for all the emetogens tested.
http://www.euroanesthesia.org/education/rc_vienna/09rc4.HTM   (3163 words)

  
 Cannabis Research - Medical Uses - anti-emetic
Efficacy of tetrahydrocannabinol in patients refractory to standard antiemetic therapy.
The antiemetic activity and side-effects of delta-9-tetrahydrocannabinol (THC) were evaluated in 116 patients (median age 61 years) receiving combined 5-fluorouracil and semustine (methyl CCNU) therapy for gastrointestinal carcinoma.
Significant advances in the treatment of certain disseminated malignancies have been accompanied by an increased awareness of the consequences of inadequate antiemetic therapy.
http://www.ukcia.org/research/medline/5b.htm   (4500 words)

  
 PREVENTION OF CHEMOTHERAPY-INDUCED NAUSEA AND VOMITING
Antiemetic therapy should be given on a scheduled basis, around the clock, throughout the period of anticipated emetic response.
In an effort to expand the number of patients who achieve complete response to antiemetic therapy in general, recent literature has explored the potential benefits of combination antiemetic therapy.
It is important the for the clinician to consider any physical or psychosocial factors when choosing a patient's antiemetic therapy.
http://daccx.bsd.uchicago.edu/drug/Bulletins/n0696.html   (3912 words)

  
 CancerNausea.com - Medications to Prevent or Control CINV, RINV, and PONV
They are often combined with other antiemetic medicines like serotonin antagonists and corticosteroids to increase their effectiveness.
For this reason, antiemetic medicines are best given immediately before chemotherapy or radiation therapy.
Like most medicines, antiemetics are all slightly different and may work better for some patients than others.
http://www.cancernausea.com/treatment_options/medications.asp   (2221 words)

  
 Chemotherapy-Induced Nausea and Vomiting: The Importance of Acute Antiemetic Control -- Schnell 8 (2): 187 -- The ...
is an important goal of antiemetic therapy [7].
prophylaxis is achieved by tailoring antiemetic therapy to the
Effectiveness of serotonin-receptor antagonist antiemetic therapy over successive courses of carboplatin-based chemotherapy.
http://theoncologist.alphamedpress.org/cgi/content/full/8/2/187   (5687 words)

  
 Delta-9-Tetrahydrocannibinol as an Antiemetic in Cancer Patients Receiving High-Dose Methotrexate (Annals of Internal ...
The concomitant infusion of a chemotherapeutic drug may have precluded any appetite-enhancing actions of THC in our patient population.
Controlled clinical studies of orally administered antiemetic drugs.
Clearly, an alternative parenteral drug route needs to be established if THC is to have wide clinical acceptability.
http://www.thecompassionclub.org/library/antiemetic7.html   (4048 words)

  
 A risk score-dependent antiemetic approach effectively reduces postoperative nausea and vomiting - a continuous quality ...
Antiemetic prophylaxis does not improve outcomes after outpatient surgery when compared to symptomatic treatment.
(multimodal approach) is superior to a single antiemetic.
antiemetic strategy could effectively reduce the incidence of
http://www.cja-jca.org/cgi/content/full/51/4/320   (2714 words)

  
 TriCenturion
There must also be a statement on the order which indicates that the oral antiemetic drug is a full therapeutic replacement for an intravenous antiemetic drug and is used as part of a cancer chemotherapy regimen.
The supplier may dispense only a single course of oral antiemetic drugs at one time.
Claims submitted by entities not licensed to dispense drugs will be denied for lack of medical necessity.
http://www.tricenturion.com/content/dmerc/rev17_ch19_misc-oral_antiemetic.cfm   (1530 words)

  
 Defining the Emetogenicity of Cancer Chemotherapy Regimens: Relevance to Clinical Practice -- Hesketh 4 (3): 191 -- The ...
of combination antiemetic therapy, tailoring therapy for both
emesis in the absence of effective antiemetic prophylaxis.
The National Comprehensive Cancer Network makes no warranties of any kind whatsoever regarding their content, use, or application and disclaims any responsibility for their application or use in any way.
http://theoncologist.alphamedpress.org/cgi/content/full/4/3/191   (2392 words)

  
 (S-8) THE EFFECTIVENESS OF RESCUE ANTIEMETICS IN PATIENTS WHO RECEIVED A PROPHYLACTIC ANTIEMETIC
Data from a large multicenter study was analyzed to investigate the efficacy of rescue antiemetics.
The choice of antiemetic was left to the discretion of the anesthesiologists.
METHODS: Following IRB approval and informed consent, 2061 adult surgical outpatients at high risk for PONV were randomized to receive one of 4 prophylactic antiemetics Droperidol 0.625mg, Droperidol 1.25mg, Ondansetron 4mg or placebo at induction of anesthesia.
http://www.iars.org/abstracts/abstracts/S1/S8.htm   (292 words)

  
 Peer Reviewed Results of New York State-sponsored Cancer/Marijuana Studies
Cassileth PA, Lusk EJ, Torri S, et al: Antiemetic efficacy of dexamethasone therapy in patients receiving cancer chemotherapy.
Kris MG, Gralla RJ, Tyson LB, et al: Improved control of cisplatin-induced emesis with high-dose metoclopramide, and with combinations of metoclopramide, dexamethasone, and diphenhydramine.
Carey MP, Burish TG, Brenner DE: Delta-9-tetrahydrocannabinol in cancer chemotherapy: Research problems and issues.
http://www.medmjscience.org/Pages/science/vinciguerra.html   (1946 words)

  
 Recommendations for the Use of Antiemetics: Evidence-Based, Clinical Practice Guidelines -- Gralla et al. 17 (9): 2971 ...
therapy, the patient should be given antiemetics appropriate
Weeks JC: Special issues that arise in applying techniques of economic analysis to evaluation of cancer therapies.
equally effective and are as safe as intravenous antiemetics.
http://www.jco.org/cgi/content/full/17/9/2971   (8657 words)

  
 The safety and effectiveness of antiemetic therapy for NVP
The safety and effectiveness of antiemetic therapy for NVP
One small trial of 30 women with severe NVP found that ondansetron was no more effective than promethazine.
Teaching Attending Physician, Obstetric and General Internal Medicine, Mount Sinai Hospital, Staff, the Motherisk Program, the Hospital for Sick Children, Assistant Professor of Medicine, University of Toronto, Toronto, Canada
http://www.nvp-volumes.org/p1_11.htm   (1931 words)

  
 Medical Marijuana: Nausea and Vomiting
Gralla and colleagues (1984) examined metoclopramide versus dronabinol in patients given cisplatin in a randomized double-blind trial.
Gralla, R.J.; Tyson, L.B.; Bordin, L.A.; Clark, R.A.; Kelsen, D.P.; Kris, M.G.; Kalman, L.B.; and Groshen, S. Antiemetic therapy: A review of recent studies and a report of a random assignment trial comparing metoclopramide with delta-9-tetrahydrocannabinol.
Report of patient data from randomized trials of placebo antiemetics with cisplatin.
http://www.hivpositive.com/f-Nutrition/MedicalMarijuana/MM-Nausea.html   (811 words)

  
 Ginger Brew - The Joy of Ginger
In addition to the previously mentioned antiemetic properties of ginger there are many other benefits associated with the digestive system.
Chinese medicine has incorporated ginger in remedies for the digestive system for centuries and it is regularly used as a calmative for stomach upsets.
Ginger is "an effective and promising prophylactic antiemetic, which may be especially useful for day case surgery." (1)
http://www.gingerbrew.com/health.php   (2663 words)

  
 Influence of Antipsychotic, Antiemetic, and Ca2+ Channel Blocker Drugs on the Cellular Accumulation of the Anticancer ...
Several drugs found to modulate Pgp function by the flow cytometric method were selected for the proliferation assay (Figs.
Modulation of P-glycoprotein Function by Some Drugs as Tested by Flow Cytometry.
) cells by antiemetic drugs using rhodamine123 as a substrate.
http://www.jpet.org/cgi/content/full/295/3/1276   (4897 words)

  
 Multinational Association of Supportive Care in Cancer
The 2004 Perugia Antiemetic Consensus Guideline process: methods, procedures, and participants
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Antiemetic therapy for multiple-day chemotherapy and high-dose chemotherapy with stem cell transplant: review and consensus statement
http://www.mascc.org/index.php?load=pro_study_groups&page_id=86   (349 words)

  
 POSTER 117
  This study is an open label, cross-over design (15 mgs/30 mgs) to provide an initial test of the analgesic and antiemetic characteristics of mirtazapine in a series of 20 cancer patients on opioid therapy for cancer related pain.
AN INVESTIGATION OF THE ANALGESIC AND ANTIEMETIC EFFICACY OF MIRTAZAPINE (REMERON) IN CANCER  PAIN PATIENTS.
http://www.medlib.iupui.edu/faculty/scs2000/p117.htm   (227 words)

  
 National Cancer Institute - Marijuana Use in Supportive Care for Cancer
To address issues surrounding the medical uses of marijuana, the National Institutes of Health convened a meeting in February 1997 to review the scientific data concerning its potential therapeutic uses and explore the need for additional research.
Although patients usually receive antiemetics, drugs that help control nausea and vomiting, there is no single best approach to reducing these symptoms in all patients.
National Cancer Institute (NCI) scientists feel that other antiemetic drugs or combinations of antiemetic drugs have been shown to be more effective than synthetic THC as “first-line therapy” for nausea and vomiting caused by anticancer drugs.
http://www.cancer.gov/cancertopics/factsheet/support/marijuana   (915 words)

  
 antiemetic - definition of antiemetic by the Free Online Dictionary, Thesaurus and Encyclopedia.
Phenergan, promethazine - antihistamine (trade name Phenergan) used to treat allergies; also an antiemetic used to treat motion sickness
prochlorperazine - antipsychotic and antiemetic drug used to treat schizophrenia and to combat nausea and vomiting
antiemetic - a drug that prevents or alleviates nausea and vomiting
http://www.thefreedictionary.com/antiemetic   (156 words)

  
 New Antiemetic Drug Introduced For Use in Chemotherapy and Surgery
New Antiemetic Drug Introduced For Use in Chemotherapy and Surgery
mesylate), an antiemetic used for the prevention of nausea and vomiting in chemotherapy and surgery patients.
KANSAS CITY, MO. -- October 6, 1997 -- The U.S. Food and Drug Administration has cleared for marketing the oral and intravenous formulations of Hoechst Marion Roussel’s Anzemet® (dolasetron
http://www.pslgroup.com/dg/3c032.htm   (366 words)

  
 UpToDate Characteristics of antiemetic drugs
Thus, drug selection in many clinical situations is based upon empiricism, the preferred route of administration, and safety.
A general approach to the patient with nausea and vomiting and the treatment of nausea and vomiting caused by gastric dysmotility are discussed separately.
The available antiemetic drugs will be reviewed here, using a classification system based upon their site of action.
http://patients.uptodate.com/topic.asp?file=gi_dis/12256   (395 words)

  
 Antiemetic
(a) An over-the-counter antiemetic drug product in a form suitable for oral administration is generally recognized as safe and effective and is not misbranded if it meets each of the conditions in this part and each of the general conditions established in Sec.
[[Page 232]] Subpart C--Labeling 336.50 Labeling of antiemetic drug products.
The labeling of the product contains the established name of the drug, if any, and identifies the product as an ``antiemetic.'' (b) Indications.
http://www.fda.gov/cder/otcmonographs/Antiemetic/antiemetic(336).htm   (913 words)

  
 CancerNausea.com - Choosing the right antiemetic
Could they forget to take their prescribed antiemetic?
Does the patient have renal or hepatic disease?
Choose an antiemetic with no dose adjustment required in hepatically or renally impaired patients
http://www.cancernausea.com/splfeatures/choose_antiemetic.asp   (238 words)

  
 Aprepitant: A Novel Antiemetic for Chemotherapy-Induced Nausea and Vomiting -- Massaro and Lenz 39 (1): 77 -- The ...
CONCLUSIONS: Triple antiemetic therapy with aprepitant, a corticosteroid,
Aprepitant: A Novel Antiemetic for Chemotherapy-Induced Nausea and Vomiting -- Massaro and Lenz 39 (1): 77 -- The Annals of Pharmacotherapy
Articles by Massaro, A. Articles by Lenz, K. Aprepitant: A Novel Antiemetic for Chemotherapy-Induced Nausea and Vomiting
http://www.theannals.com/cgi/content/abstract/39/1/77   (316 words)

  
 The Body: Chemotherapy and You: A Guide to Self-Help During Treatment
Different drugs work for different people, and it may be necessary to use more than one drug to get relief.
If you experience this side effect, your doctor can choose from a range of drugs known as antiemetics, which help curb nausea and vomiting.
Nausea and vomiting almost always can be controlled or at least lessened.
http://www.thebody.com/nih/chemotherapy/chemotherapy3.html   (5477 words)

  
 Treatments: Antiemetic - CureResearch.com
Count: Antiemetic is listed as a: treatment for 0 conditions; alternative treatment for 0 conditions; preventive treatment for 0 conditions; research treatment for 0 conditions.
Use of this site is subject to our TERMS OF USE.
Antiemetic: Class of drugs against nausea and vomiting
http://www.cureresearch.com/treat/antiemetic.htm   (196 words)

  
 Antiemetic - Wikipedia, the free encyclopedia
Antiemetics are typically used to treat motion sickness and the side effects of opioid analgesics and chemotherapy directed against cancer.
An antiemetic is a drug that is effective against vomiting and nausea.
This page was last modified 13:11, 15 January 2006.
http://en.wikipedia.org/wiki/Antiemetic   (71 words)

  
 Clinical Trial: Comparison of Antiemetic Drugs in Preventing Delayed Nausea After Chemotherapy in Patients With Cancer
RATIONALE: Antiemetic drugs may help to reduce or prevent nausea and vomiting in patients being treated with chemotherapy.
Comparison of Antiemetic Drugs in Preventing Delayed Nausea After Chemotherapy in Patients With Cancer
PURPOSE: Randomized phase III trial to compare the effectiveness of different antiemetic drugs in preventing delayed nausea after chemotherapy in patients who have cancer.
http://www.clinicaltrials.gov/ct/gui/show/NCT00020657   (642 words)

  
 Antiemetic Therapy Guidelines
Lorazepam is a weak antiemetic and should be considered for patients with significant anxiety.
Delayed emesis regimen (For all patients receiving cisplatin > or =25 mg/m
Duke University Health System's 2000 Antiemetic Guidelines For Chemotherapy
http://www2.mc.duke.edu/depts/hospital/9200bmt/antiemetics.htm   (273 words)

  
 Improving the Care of Patients With Regard to Chemotherapy-Induced Nausea and Emesis: The Effect of Feedback to ...
Improving the Care of Patients With Regard to Chemotherapy-Induced Nausea and Emesis: The Effect of Feedback to Clinicians on Adherence to Antiemetic Prescribing Guidelines -- Mertens et al.
http://www.jco.org/cgi/reprint/21/7/1373   (36 words)

  
 Arch Pediatr Adolesc Med -- Abstract: Antiemetic Use for Acute Gastroenteritis in Children, May 2003, Li et al. 157 ...
for an antiemetic is associated with a significant risk of adverse
Conclusion  Antiemetic use among children with acute gastroenteritis
an antiemetic prescription was filled and for those who did
http://archpedi.ama-assn.org/cgi/content/abstract/157/5/475   (313 words)

  
 Antiemetic treatment in patients (pts) submitted to consecutive days of 5-Fluorouracil (5-FU) ± folinic acid (FA)
Methods: To evaluate to behavior of Italian oncologists on such issue, we analyzed this category of pts as part of a multicenter, prospective, observational study on antiemetic drug utilization in pts submitted to cancer CT of different emetogenic potential.
Two hundred and nineteen pts (84.5%) received an antiemetic prophylaxis: 43.4% a 5-HT3 antagonist ± steroids, 37.5% an antidopaminergic drug (metoclopramide or alizapride), 10.9% a steroid ± antidopaminergic drug and 8.2% other drugs.
At unifactorial analysis, the previous experience of V/N by CT was found a significant prognostic factor.
http://www.esmo.org/reference/abstracts/psc/680.htm   (402 words)

  
 Serotonin - Wikipedia, the free encyclopedia
They are particularly important in treating the nausea and vomiting that occur during anticancer chemotherapy using cytotoxic drugs.
5-HT antagonists such as ondansetron, granisetron and tropisetron are important antiemetic agents.
http://en.wikipedia.org/wiki/Serotonin   (935 words)

  
 NEJM -- Antiemetic Effects of Ondansetron and Metopimazine
NEJM -- Antiemetic Effects of Ondansetron and Metopimazine
and safe antiemetic regimen that is markedly superior to treatment
The primary end point of antiemetic treatment is complete protection
http://content.nejm.org/cgi/content/short/329/18/1356-a   (133 words)

  
 Antiemetic definition - Medical Dictionary definitions of popular medical terms
As a noun, a drug taken to prevent or treat nausea and vomiting.
Antiemetic definition - Medical Dictionary definitions of popular medical terms
MedicineNet Home > MedTerms medical dictionary A-Z List > Antiemetic
http://www.medterms.com/script/main/art.asp?articlekey=33265   (168 words)

  
 Major Exam 5: "Antianxiety, Antidepressant, Antipsychotic, Antiemetic & Antivertigo"
Major Exam 5: "Antianxiety, Antidepressant, Antipsychotic, Antiemetic & Antivertigo"
Betty Chong-Menard, R.R.T., R.N. / Libby De Leon, R.N. Read Antianxiety, Antidepressant, Antipsychotic, Antiemetic & Antivertigo Drugs Unit from your textbook and answer the questions below.
http://edtech.utb.edu/quizserver/quizzes/hprs230001/quiz5hprs2300.html   (295 words)

  
 The Cancer Center at HUMC-Glossary
Antiemetic: A medicine that prevents or controls nausea and vomiting.
Does not invade nearby tissue or spread to the other parts of the body.
Symptoms of anemia include feeling tired, weak, and short of breath.
http://www.humc.com/cancercenterNew/index.php?category=secondary&page=glossary   (726 words)

  
 Antiemetic
This website has information on emend antiemetic or
http://www.meddex.net/antiemetic/antiemetic.html   (8 words)

  
 A Comparison of the Costs and Efficacy of Ondansetron Versus Dolasetron for Antiemetic Prophylaxis -- Zarate et al. 90 ...
no differences in the antiemetic efficacy of the 4 and 8 mg
A Comparison of Three Antiemetic Combinations for the Prevention of Postoperative Nausea and Vomiting
The Effect of Timing of Dolasetron Administration on its Efficacy as a Prophylactic Antiemetic in the Ambulatory Setting
http://www.anesthesia-analgesia.org/cgi/content/abstract/90/6/1352   (907 words)

  
 Antiemetic
and this is the best resource on and antiemetic and best
http://www.tabbox.net/antiemetic/antiemetic.html   (11 words)

  
 Buy Meclizine HCl, USP 12.5 mg, Antiemetic, Tablets Online at drugstore.com
Buy Meclizine HCl, USP 12.5 mg, Antiemetic, Tablets Online at drugstore.com
http://www.drugstore.com/product.asp?pid=44340   (444 words)

  
 Listserve For EmergencyMedical Practioners: Re: [EMED-L] Zofran
: Fergus Thornton: "Re: [EMED-L] Zofran as antiemetic"
: Lovenstein, Jennifer: "Re: [EMED-L] Zofran as antiemetic"
http://www.ucsf.edu/its/listserv/emed-l/19398.html   (349 words)

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