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Topic: Anticholinergic



  
 Anticholinergic drugs used in Parkinson's disease: An overlooked class of drugs from a pharmacokinetic perspective.
Anticholinergic drugs used in Parkinson's disease: An overlooked class of drugs from a pharmacokinetic perspective.
Although this poor tolerability of the elderly towards anticholinergic drugs is a clinically important observation, it is rather surprising that there are only a few reports in the literature dealing with the pharmacokinetics of the ACP in the elderly.
Anticholinergic Drugs Used In Parkinson's Disease: An Overlooked Class Of Drugs From A Pharmacokinetic Perspective.
http://www.ualberta.ca/~csps/JPPS2(2)/D.Brocks2/anticholinergic.htm   (4328 words)

  
 GTP cyclohydrolase I mutations in patients with dystonia responsive to anticholinergic drugs -- Jarman et al. 63 (3): ...
Anticholinergic drug therapy is widely recognised to be of benefit in some patients with primary torsion dystonia.
Anticholinergic therapy is therefore not a substitute for levodopa
Not all patients with clinically definite dopa responsive dystonia respond to anticholinergic drugs.
http://www.jnnp.com/cgi/content/full/63/3/304   (2809 words)

  
 Anticholinergics in Asthma/COPD
Combined anticholinergic therapy in the management of acute asthma.
The clinical efficacy of combination nebulized anticholinergic and adrenergic bronchodilators vs nebulized adrenergic bronchodilator alone in acute asthma.
Rudolf M. Combination therapy--a review of clinical studies.
http://www.umdnj.edu/rspthweb/bibs/antichol.htm   (689 words)

  
 News - Anticholinergic Drugs May Influence Verbal Memory In Patients With Schizophrenia
Anticholinergic drugs may impede on semantic organisation at encoding, contributing to the verbal memory deficit observed in patients with schizophrenia, new research suggests.
Previous studies have shown an association between anticholinergicity and verbal memory impairment.
Anticholinergic Drugs May Influence Verbal Memory In Patients With Schizophrenia
http://www.docguide.com/news/content.nsf/news/8525697700573E1885256E4700471549?OpenDocument&id=48DDE4A73E09A969852568880078C249&c=Schizophrenia&count=10   (427 words)

  
 Anticholinergic agents for chronic asthma in adults (Cochrane Review)
Objectives: To examine the effectiveness of anticholinergic agents versus placebo and in comparison with ß2 -agonists or as adjunctive therapy to ß2 -agonists.
The role of long term anticholinergics such as tiotropium bromide has yet to be established in patients with asthma and any future trials might draw on the messages derived from this review.
Authors' conclusions: Overall this review provides no justification for routinely introducing anticholinergics as part of add-on treatment for patients whose asthma is not well controlled on standard therapies.
http://www.update-software.com/abstracts/AB003269.htm   (645 words)

  
 Central Anticholinergic Syndrome on Almondnet
Anticholinergic drugs are less effective than levodopa in treating Parkinson's disease but are used: in combination with levodopa, particularly when tremor is a particular problem
Find anticholinergic drugs and more at Lycos Search.
To determine the effectiveness of anticholinergic drugs for the treatment of overactive...
http://www.siuk.org.uk/schb/central_anticholinergic_syndrome.html   (382 words)

  
 Anticholinergic drugs: response of parkinsonism not responsive to levodopa -- Yamada et al. 72 (1): 111 -- Journal of ...
Anticholinergic drugs: response of parkinsonism not responsive to levodopa
Anticholinergic drugs: response of parkinsonism not responsive to levodopa -- Yamada et al.
Ishikawa A, Tsuji S. Clinical analysis of 17 patients in 12 Japanese families with autosomal-recessive type juvenile parkinsonism.
http://jnnp.bmjjournals.com/cgi/content/full/72/1/111   (1382 words)

  
 Hybrid Publishing -- Serum Anticholinergic Activity and Delirium
The results of the study show that patients in the intervention group had less delirium after their anticholinergic load was reduced.
Recent research into the mechanisms of delirium suggests a role for central cholinergic neurotransmission impairment as the final common pathway for the development of this condition.
In an effort to further assess the relationship between anticholinergic load and delirium, researchers studied 34 residents in three nursing homes.
http://hybridpub.com/eldercare/cme703_tune.html   (999 words)

  
 Side Effects of Anticholinergic Drugs
Many of the prescription drugs used in the treatment of Parkinson's disease, depression, allergies, migraine, and irritable bowel syndrome (IBS), fall into this category, as do some pain relieving drugs.
Doctors may assume that any side-effects are an inevitable part of the ageing process rather than something which could be avoided by altering existing medication regimes.
Many medications, both prescription and non-prescription work by blocking the action of acetylcholine including antihistamines, cold remedies, dopamine agonists, antidepressants etc. It is very easy for the effect of these medications to "add up" if several are taken, for various reasons, at the same time.
http://www.pspinformation.com/medicine/interactions/anti.shtml   (999 words)

  
 Anticholinergic medications for urinary incontinence in women
A recent study showed an 85% reduction in urge incontinence using anticholinergic medication and behavioral techniques, compared with 72% and 57% reduction after using only anticholinergic medications or behavioral techniques.
In other words, using anticholinergic medication and behavioral techniques together reduces urge incontinence better than either treatment used alone.
If you develop diarrhea while taking an anticholinergic medication, stop taking it and call your doctor.
http://my.webmd.com/hw/urinary_control/te7892.asp   (434 words)

  
 Anticholinergic medications for cerebral palsy - [Medication] - Quest Diagnostics Patient Health Library
Anticholinergic medications are used to treat muscle stiffness, tremors, and spasms.
Anticholinergics should not be taken along with antihistamine medications that can be bought without a prescription (such as Benadryl) to treat colds, the flu, or allergies; using anticholinergics with antihistamines further increases mouth dryness and dryness in other moist, mucous-lined areas in the body.
Anticholinergic medications reduce uncontrollable body movements in people who have dystonic cerebral palsy.
http://www.questdiagnostics.com/kbase/topic/detail/drug/ue5187/detail.htm   (256 words)

  
 Long-acting inhaled anticholinergic therapy improves sleeping oxygen saturation in COPD -- McNicholas et al. 23 (6): ...
Long-acting inhaled anticholinergic therapy improves sleeping oxygen saturation in COPD -- McNicholas et al.
Long-acting inhaled anticholinergic therapy improves sleeping oxygen saturation in COPD
http://erj.ersjournals.com/cgi/content/abstract/23/6/825   (259 words)

  
 Review: anticholinergic drugs improve symptoms but increase dry mouth in adults with overactive bladder syndrome -- ...
The reviewers conclude that use of anticholinergic medication
In 13 parallel arm studies, anticholinergic drugs and placebo
Meta-analysis of parallel arm studies showed that patients who
http://ebn.bmjjournals.com/cgi/content/full/6/2/49   (578 words)

  
 The Association of Serum Anticholinergic Activity With Delirium in Elderly Medical Patients -- Flacker et al. 6 (1): 31 ...
Golinger R, Peet T, Tune L: Association of elevated plasma anticholinergic activity with delirium in surgical patients.
of atropine that would be as anticholinergic as the subject's
which serum anticholinergic activity is affected by any of the
http://ajgp.psychiatryonline.org/cgi/content/full/6/1/31   (3300 words)

  
 Reducing prescribing of highly anticholinergic antidepressants for elderly people: randomised trial of group versus ...
In both intervention arms the incidence of prescribing less anticholinergic antidepressants for patients aged
We think the observed changes over time are not due to a "regression to the mean" effect.
with a less anticholinergic antidepressant after the intervention
http://www.bmj.com/cgi/content/full/322/7287/654   (3101 words)

  
 Site Index 25: University Health of Augusta, Georgia
Anticholinergic medications for cerebral palsy - What To Think About
Anticholinergic medications for urinary incontinence - What To Think About
Anticholinergic medications for cerebral palsy - How It Works
http://www.universityhealth.org/1025.cfm   (469 words)

  
 Virtual Hospital: Clinical Psychopharmacology Seminar : Anticholinergic Psychosis
Extreme caution should be exercised before vigorous physostigmine treatment is instituted in patients with these conditions.
The drug has both central and peripheral cholinomimetic actions (Granacher and Baldessarini 1975).
Physostigmine: its use in acute anticholinergic syndrome with antidepressant and antiparkinson drugs.
http://www.vh.org/adult/provider/psychiatry/CPS/25.html   (1913 words)

  
 Effectiveness of anticholinergic drugs compared with placebo in the treatment of overactive bladder: systematic review ...
that the use of placebo arms in trials with anticholinergic drugs
Our study was carried out under the auspices of the Cochrane Incontinence Group.
For many of the outcomes studied, the observed difference between
http://bmj.com/cgi/content/full/326/7394/841   (3098 words)

  
 Oxytrol (Transdermal Oxybutynin) Calms Overactive Bladder Without Excessive Anticholinergic Side Effects
Dry mouth occurred in 9.6 percent of patients in the 3.9 mg/day transdermal oxybutynin group and in 8.3 percent of those receiving placebo.
One theory for the observed reduction in anticholinergic side effects is the novel delivery system.
Overactive bladder is a condition characterized by symptoms of urinary frequency, urgency and urge incontinence, and has typically been treated with anticholinergic drugs such as oxybutynin.
http://www.docguide.com/dg.nsf/PrintPrint/0BB3BA4AA566CA6585256AA8004BE8DA   (615 words)

  
 anticholinergic: Definition and Much More From Answers.com
Many other drugs have anticholinergic properties, including cyclic antidepressants and the common allergy medications diphenhydramine (Benadryl) and its 8-chlorotheophylline salt dimenhydrinate (Dramamine), which are used medically for antihistaminergic and antiemetic purposes, and sometimes recreationally for their psychoactive effects.
This may happen accidentally or intentionally as a form of recreational drug use.
However, in extreme cases, especially those that involves severe distortions of mental state, a reversible cholinergic agent such as physostigmine may be used.
http://www.answers.com/topic/anticholinergic   (505 words)

  
 © Priory Lodge Education Limited, 1996.
The research evidence proporting and refuting such practice remains inconclusive and the recommendation that anticholinergic drugs should be administered prophylactically has attracted several critics (Klett et al, 1972; Mindham et al, 1972; McClelland et al, 1974; Mindham 1976; McClelland 1976).
Since such treatment results in an increase in morbidity (May & Simpson, 1980), it is important to try and distinguish the group of patients who need prophylactic anticholinergic drugs from those who do not.
Therefore, if anticholinergic drugs are used prophylactically many patients are unnecessarily treated with these.
http://www.priory.com/psych/frames/long.htm   (946 words)

  
 Chronic Exposure to Anticholinergic Medications Adversely Affects the Course of Alzheimer Disease -- Lu and Tune 11 ...
TABLE 1. Medications with anticholinergic effects (adapted from Tune and Egeli
Folstein MF, Folstein SE, McHugh PR: Mini-Mental State: a practical method for grading the cognitive state of patients for the clinician.
therapy with anticholinergic medications may be associated with
http://ajgp.psychiatryonline.org/cgi/content/full/11/4/458   (1143 words)

  
 UpToDate Role of anticholinergic therapy in COPD
It is important to recognize that regular long-term therapy with bronchodilators does not alter the natural history of COPD, as was clearly demonstrated by the outcome of the Lung Health Study [1].
By comparison, there is currently no effective therapy for the irreversible airflow obstruction that results from airway obliteration, peribronchial and peribronchiolar fibrosis, and loss of elastic recoil.
In addition, combination therapy with both beta-agonist and anticholinergic bronchodilators may be helpful in some patients.
http://patients.uptodate.com/topic.asp?file=copd/4991   (447 words)

  
 FDA > CDRH > CFR Title 21 Database Search
There are inadequate safety and effectiveness data to establish general recognition of the safety and/or effectiveness or any of these ingredients, or any other ingredient, for OTC use as an anticholinergic in cough-cold drug products.
(c) Clinical investigations designed to obtain evidence that any cough-cold drug product labeled, represented, or promoted for OTC use as an anticholinergic is safe and effective for the purpose intended must comply with the requirements and procedures governing the use of investigational new drugs set forth in part 312 of this chapter.
Anticholinergic drugs have been marketed OTC in cough-cold drug products to relieve excessive secretions of the nose and eyes, symptoms that are commonly associated with hay fever, allergy, rhinitis, and the common cold.
http://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?fr=310.533   (393 words)

  
 Drug Crisis Response
It's possible, for example, for a person taking one product for sniffles, say, and another for diarrhea and yet another for depression to be completely unaware of the risk of drug synergism.
If the earlier sections constituted the bare bones of drug crisis response, this chapter represents the skin and teeth and bones and hair.
These drugs, which include a variety of prescription and non-prescription medications based on the plant belladonna and its derivatives, are used to treat problems as diverse (and far-flung) as sinus congestion and irritable bowel syndrome.
http://www.doitnow.org/pages/208/208-7.html   (1556 words)

  
 Safety and efficacy of an anticholinergic injection used in a community smoking cessation clinic -- Voelker 126 (4): ...
Safety and efficacy of an anticholinergic injection used in a community smoking cessation clinic -- Voelker 126 (4): 713S -- Chest Meeting Abstracts
is then prescribed anticholinergic medications to continue the
up and counseling and or a repeat anticholinergic shot, we were
http://meeting.chestjournal.org/cgi/content/abstract/126/4/713S-a   (291 words)

  
 Active Skim View of: Appendix J: Anticholinergic Drugs and the EEG-- by Max Fink, Ph.D.
Conaiderlag the many hundred a of patlenta 90 created and the continuation of this form of therapy in patients in eastern Europe today, it is unlikely that there is a behavioral syndrome of toxicity.
T.M. 1966 : Quantltative EEG changea induced by anticholinergic druga and their behavioral correlates in man.
Focusing exclusively on the anticholinergic properties of the drugs examined in military volunteers, considering the low doses used and the minimal exposures, ant aware that heroic doses of ant!
http://www.nap.edu/nap-cgi/skimit.cgi?isbn=POD090&chap=263-270   (386 words)

  
 MedlinePlus Medical Encyclopedia: Glaucoma
Careful use of dilating eye drops and systemic anticholinergic medications will minimize the risk of acute attacks in high-risk individuals.
Use of systemic anticholinergic medications (such as atropine or eye dilation drops) in a high-risk individual
Patients with risk factors for closed angle glaucoma should be evaluated and those at high risk should have laser iridotomy, which will prevent acute attacks.
http://www.nlm.nih.gov/medlineplus/ency/article/001620.htm   (1249 words)

  
 Synonyms of anticholinergic
anticholinergic, anticholinergic drug, medicine, medication, medicament, medicinal drug
usage: inhibiting or blocking the action of acetylcholine at a receptor site; "anticholinergic drugs"
http://www.infoplease.com/thesaurus/anticholinergic   (49 words)

  
 Spirometric Correlates of Improvement in Exercise Performance after Anticholinergic Therapy in Chronic Obstructive ...
dyspnea in response to acute high-dose anticholinergic therapy
The study included 29 patients with stable COPD who satisfied the following criteria: (1) moderate to severe COPD (FEV
Spirometric Correlates of Improvement in Exercise Performance after Anticholinergic Therapy in Chronic Obstructive Pulmonary Disease
http://www.ajrccm.org/cgi/content/full/160/2/542   (5082 words)

  
 Long-Term Response to Tiotropium, an Anticholinergic Bronchodilator for COPD - Journal Watch (General)
Long-Term Response to Tiotropium, an Anticholinergic Bronchodilator for COPD
Long-Term Response to Tiotropium, an Anticholinergic Bronchodilator for COPD - Journal Watch (General)
Tiotropium is a new inhaled anticholinergic bronchodilator that
http://general-medicine.jwatch.org/cgi/content/full/2003/527/1   (215 words)

  
 s000321a - Anticholinergic Syndrome
Diagnosis of this potentially fatal condition rests on a detailed history and observation of peripheral and central anticholinergic signs.
While supportive therapy is sufficient in most patients, some require treatment with physostigmine.
Title: The anticholinergic intoxication syndrome: diagnosis and treatment.
http://www.emory.edu/WHSCL/grady/amreport/litsrch99/s000321a.html   (572 words)

  
 Acute anticholinergic syndrome (Treatment Guide)
Other laboratory examinations may be needed as dictated by the general condition of the patient.
CLINICAL FEATURES The clinical diagnosis is based on the appearance of the anticholinergic toxidrome.
DIFFERENTIAL DIAGNOSIS Alcohol withdrawal Organic delirium (usually secondary to sepsis) Psychiatric illness Psychedelic drugs Sympathomimetic drugs RELEVANT INVESTIGATIONS Measurement of blood and urine levels of the anticholinergic agents are of little or no practical value.
http://www.intox.org/databank/documents/treat/treate/trt05_e.htm   (422 words)

  
 Anticholinergic sensitivity in the aging rat septohippocampal system as assessed in a spatial memory task.
Since the same behavioral deficit was produced by cholinergic blockade in young rats with septal lesions, we concluded that the impaired water maze performance seen in the aged rats during cholinergic blockade resulted from impaired function in the septohippocampal system.
Anticholinergic sensitivity in the aging rat septohippocampal system as assessed in a spatial memory task.
The effects of central cholinergic blockade on spatial memory were tested in aged and basal forebrain-lesioned rats using the Morris Water Maze.
http://www.arclab.org/medlineupdates/abstract_8247231.html   (289 words)

  
 Amazon.ca: Books: Anticholinergic Agents in the Upper and Lower Airways
Discusses anticholinergic agents, integrating the treatment of rhinitis, the common cold, and asthma in the upper and lower airways, while updating the latest therapeutic practices.
Discusses anticholinergic agents, integrating the treatment of rhinitis, the common cold, and asthma in the upper and lower airways.
Use Your Account to view or change your orders
http://www.amazon.ca/exec/obidos/ASIN/082471959X   (202 words)

  
 Anticholinergic potency of diphenhydramine (Benadryl) measured against bethanechol in the gastric fistula dog -- ...
Anticholinergic potency of diphenhydramine (Benadryl) measured against bethanechol in the gastric fistula dog -- Hirschowitz and Molina 226 (1): 171 -- Journal of Pharmacology And Experimental Therapeutics
Anticholinergic potency of diphenyhydramine was 10,000 times less than that
We quantitated the gastric secretory anticholinergic effect of
http://jpet.aspetjournals.org/cgi/content/abstract/226/1/171   (141 words)

  
 Anticholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive ...
Anticholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease (Cochrane Review)
Anticholinergic bronchodilators versus beta2-sympathomimetic agents for acute exacerbations of chronic obstructive pulmonary disease.
Background: Inhaled bronchodilators form the mainstay of treatment for acute exacerbations of COPD.
http://www.update-software.com/abstracts/ab003900.htm   (514 words)

  
 Anticholinergic therapy for bronchiectasis (Cochrane Review)
Authors' conclusions: No formal recommendations can be made about the use of anticholinergic therapy in acute or stable bronchiectasis based on the literature currently available.
Objectives: To determine the effect of anticholinergic therapy in acute exacerbations and stable bronchiectasis.
They are effective in obstructive airways disease and may be beneficial in bronchiectasis
http://www.cochrane.org/cochrane/revabstr/ab002163.htm   (257 words)

  
 AGS: Olanzapine Has No Anticholinergic Effects in Elderly Patients With Dementia
A study presented yesterday at the American Geriatric Society’s annual meeting by Bruce Kinon, MD and his colleagues at Lilly Research Laboratories in Indianapolis, Indiana, suggests, however, that it may - if anything - increase cholinergic activity in these patients.
Most patients had been on other psychotropic drugs prior to the study.
Peripheral anticholinergic events were measured using the UKU autonomic symptom subscale, while the Mini Mental State Exam was used to evaluate cognitive impairment.
http://www.pslgroup.com/dg/1FAC96.htm   (485 words)

  
 Cheryl's Herbs Herbal and Aromatherapy Encyclopedia
Eliminates a biliary or jaundice condition in the body.
Anticholinergic Blocking the passage of impulses through the parasympathetic nerves; parasympatholytic.
Prevents clotting in a liquid, as in blood.
http://www.cherylsherbs.com/encyclopedia.htm   (1822 words)

  
 GERD AND Anticholinergic
golfer julienne the GERD AND anticholinergic letterperfect barrenwort with cookiecutter barometric pressure.
Respectful Doctor of Science GERD AND anticholinergic deenergize the unloving opportunist
GERD AND anticholinergic Softwood misdemeanor accommodate the unbordered snit with curatorial horticulturist.
http://www.alto-infotech.com/gerd/GERD-AND-anticholinergic.html   (1635 words)

  
 The Comparative Peripheral Anticholinergic-Like Adverse Event Profiles of Olanzapine and Risperidone/PCC Abstract ...
Method: Data from a double-blind, randomized trial of olanzapine versus risperidone in 339 patients (age range, 18-65 years) with DSM-IV schizophrenia spectrum acute psychosis were retrospectively analyzed.
When only patients who did not receive anticholinergic adjunct therapy were considered, no significant differences in the frequency of specific anticholinergic adverse events occurred in olanzapine-treated patients as compared with risperidone-treated patients (p >=.245).
Subgroups based on the median of the mean daily drug dose were constructed (olanzapine <= 17 mg; olanzapine > 17 mg; risperidone <= 6 mg; risperidone > 6 mg).
http://www.psychiatrist.com/pcc/abstracts/pc020402.htm   (341 words)

  
 Anticholinergic Medicine In Quitting Smoking
Continue to take this medicine even if you feel better.
more slowly and to be more sensitive to the anticholinergic, sedative, and...
http://www.free-radical.org/anticholinergic-medicine-in-quitting-smoking.html   (168 words)

  
 Asthma Treatments: Medications and Their Effects
How they work: Inhaled anticholinergic asthma drugs relax the airway muscles much like atropine (belladonna), but without the unpleasant side effects to the nervous system.
Common drugs: Common anticholinergic drugs include Atrovent®, Combivent® and Duoneb®.
If a ß2 is followed by ipratropium, the two drugs tend to enhance each other's effects.
http://www.treatments-for-asthma.com   (799 words)

  
 Gale Encyclopedia of Psychology: Psychoactive drugs
Tardive dyskinesia, a condition characterized by involuntary movements of the mouth and other locations on the body, has been reported in some patients who take antipsychotic medication on a long-term basis.
Additional medications may also be prescribed to address severe side effects (e.g., anticholinergic medication may be prescribed for muscle spasms caused by antipsychotic medications).
In some cases, a dosage adjustment or change of prescription can alleviate any discomfort caused by them.
http://www.findarticles.com/p/articles/mi_g2699/is_0005/ai_2699000589   (914 words)

  
 eMedicine - Toxicity, Anticholinergic : Article by John J Bruns, Jr, MD
Always inquire about use of dermally applied drugs (ie, scopolamine transdermal delivery system).
Most patients can be treated safely without physostigmine, but it is recommended for use when at least one of the following aberrations are present: tachydysrhythmias with subsequent hemodynamic compromise, intractable seizures, or severe agitation or psychosis (in which the patient is considered a threat to self or others).
Asymptomatic patients without anticholinergic signs or symptoms can be discharged after a 4-6 hour observation period.
http://www.emedicine.com/emerg/topic36.htm   (3065 words)

  
 Arch Intern Med -- Abstract: A Prescribing Cascade Involving Cholinesterase Inhibitors and Anticholinergic Drugs, April ...
inhibitors and anticholinergic drugs used to manage urinary
with an increased risk of receiving an anticholinergic drug
Arch Intern Med -- Abstract: A Prescribing Cascade Involving Cholinesterase Inhibitors and Anticholinergic Drugs, April 11, 2005, Gill et al.
http://archinte.ama-assn.org/cgi/content/abstract/165/7/808   (263 words)

  
 IngentaConnect Hepatic encephalopathy - a physostigmine-reactive central anticho...
A 60-year-old anaemic woman was admitted unconscious and with a delayed reaction to pain but with no focal neurological deficits.
This report describes an association between hepatic encephalopathy and central anticholinergic syndrome (CAS).
Hepatic encephalopathy – a physostigmine-reactive central anticholinergic syndrome?
http://api.ingentaconnect.com/content/gmed/eja/1999/00000016/00000002/art00012   (240 words)

  
 ANTICHOLINERGIC TOXICITY
Conservative, supportive therapy is the mainstay of treatment of anticholinergic toxicity.
Anticholinergic medications are commonly prescribed for elderly patients, often resulting in drug-induced delirium.
The indications for its use include the presence of peripheral anticholinergic signs and seizures unresponsive to conventional therapy, uncontrollable agitation, hemodynamically unstable arrhythmias unresponsive to conventional therapy, coma with respiratory depression, malignant hypertension, or refractory hypotension.
http://www.heacamjournal.com/htdocs/pages/art/55-tox.html   (1121 words)

  
 Clinical Aspects of Inhaled Anticholinergic Therapy
[Respir Care 2000:45(7):864-867] Key words: lung disease, obstructive, bronchodilator, ipratropium, tiotropium, muscarinic, anticholinergic.
The term "anticholinergic" refers to a pharmacologic action that opposes cholinergic receptor stimulation.
In the lung, the cholinergic receptors that cause airways obstruction are of the muscarinic type.
http://www.rcjournal.com/contents/07.00/07.00.0864.asp   (223 words)

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