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Topic: Anticonvulsant



  
 © The American Physiological Society - Press Room - Anticonvulsant Drugs Found to Impact On Epileptic Children's ...
This research demonstrates the consequences of anticonvulsant therapy that may contribute to transient cognitive disabilities (impairments of attention, memory, learning and/or social behavior).
Consequently, learning can be defined as the process by which an organism benefits from experience, so that its future behavior differs from that of a comparable organism lacking this experience.
Accordingly, a research effort from Brazil has focused on problems in recall information, believing there are a subset of difficulties in learning and memory deficits, probably resulting from anticonvulsant therapy in infancy.
http://www.the-aps.org/press/conference/eb/9.htm   (986 words)

  
 Virtual Children's Hospital: Anticonvulsant Drug Therapy
There are now a number of drugs available for this purpose and the overall efficacy of anticonvulsant drug therapy is good.
As a result, any anticonvulsant can lead to changes in personality, behavior or learning ability.
One further concern is the possibility of adverse effects upon the fetus when anticonvulsant drugs are taken during pregnancy.
http://www.vh.org/pediatric/patient/neurology/anticonvulsantdrugtherapy/anticonvulsant.html   (1257 words)

  
 Which Anticonvulsant for Women With Eclampsia? Evidence from the Collaborative Eclampsia Trial
Only 7 women did not have the anticonvulsant that was originally allocated, because of errors in preparing the boxes (3), a clinical decision to give a different anticonvulsant (2) or no anticonvulsant (1), or unfamiliarity with the trial protocol (1).
Only 14 women did not have the anticonvulsant that was originally allocated, either because of errors in preparing the boxes (10) or because of a clinical decision to give a different anticonvulsant (3) or no anticonvulsant (1).
Standard practice is to use anticonvulsants to control the immediate fit and prevent further seizures, but the choice of anticonvulsant is controversial.
http://smi-web.stanford.edu/people/purcell/docs/rsch-lnct-95287707.html   (5511 words)

  
 Anticonvulsant Screening Program: National Institute of Neurological Disorders and Stroke (NINDS)
These efforts are directed toward anticonvulsant drug development and discovery of new mechanisms of drug action.
In 1968, in view of the fact that no new therapeutic candidates were available in the U.S., NINDS conducted a series of six controlled clinical trials on European drugs.
An equally important outcome of this support was the development of expertise, new methodologies, and trial designs for investigating anticonvulsant drugs.
http://www.ninds.nih.gov/funding/research/asp   (1406 words)

  
 Welcome to Raley's and Bel Air
Vitamin D metabolism and anticonvulsant therapy: effect of sunshine on incidence of osteomalacia.
Another study of 450 people in Florida taking anticonvulsants found that few had drug-induced bone disease.
Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications.
http://www.raleys.com/cfapps/healthnotesra/healthnotes.cfm?org=raleys&ContentID=1082009   (2336 words)

  
 Millipore - Technical Library - Assay of Free Anticonvulsant Drugs
When patient response to anticonvulsant drug therapy does not correspond to the measured total drug concentration, knowledge of the unbound drug concentration enables the clinician to make appropriate adjustments of the patient's therapeutic regimen.
This, of course, can considerably affect how the patient responds to the drug as well as the physician's approach and adjustment of drug therapy.
Assay of Free Anticonvulsant Drugs With separation by Centrifree® Micropartition Device
http://www.millipore.com/publications.nsf/1f3ab1fbeb242122852568f100544597/ea44460a87676c1b852568c800604ee8?OpenDocument   (1252 words)

  
 New Perspectives to the Use of Anticonvulsant Medication in Neuropsychiatry
These drugs are all technically marketed in the United States as "adjunctive anticonvulsants" as the studies examined them as adjunctive therapy to such standards as carbamazepine, valproate and phenytoin.
DÉJÀ VU New Perspectives to the Use of Anticonvulsant Medication in Neuropsychiatry
To educate in the area of epilepsy demonstrating the difficulties of research and clinical practice.
http://www.pni.org/abstracts/anticonvulsants.html   (589 words)

  
 EAGO Newsletter
The two newer second-line anticonvulsant therapies (gabapentin and lamotrigine) do not appear to be teratogenic in animal studies.
Women of child bearing age need to be counselled and told to seek advice about their anticonvulsant therapy should they wish to become pregnant.
There are various theories which try to explain why anticonvulsant drugs are teratogenic.
http://www.obgyn.net/eago/art08.htm   (1497 words)

  
 Convulsant and Anticonvulsant Effects on Spontaneous CA3 Population Bursts -- Yee et al. 89 (1): 427 -- Journal of ...
Anticonvulsant and proconvulsant actions of alpha- and beta-noradrenergic agonists on epileptiform activity in rat hippocampus in-vitro.
in vitro model in which to study anticonvulsant therapy for
In experiments 2 and 3, we were interested in examining the effects of the GABAergic anticonvulsant pentobarbital.
http://jn.physiology.org/cgi/content/full/89/1/427   (5882 words)

  
 Anticonvulsant effects of acetonic seed extract of Ferula gummosa Boiss against seizures induced by pentylenetetrazol ...
In Iranian ancient medicinal literatures, there are some reports regarding the anticonvulsant, antispasmodic, expectorant and wound-healing activities of this plant.
In Iranian traditional medicine, there are some report regarding the anticonvulsant effect of Ferula gummosa Boiss.
A proposal based on experimental and clinical considerations.
http://ibj.pasteur.ac.ir/ibj19/sayyah.htm   (2221 words)

  
 A clinical study of 57 children with fetal anticonvulsant syndromes -- Moore et al. 37 (7): 489 -- Journal of Medical ...
Risks to the offspring of women treated with hydantoin anticonvulsants, with emphasis on the fetal hydantoin syndrome.
Many studies of fetal effects of maternal anticonvulsant therapy have been based on assessments of children at birth or in
Cognitive performance in school-age offspring of epileptic mothers exposed to anticonvulsant therapy (AED) during pregnancy.
http://jmg.bmjjournals.com/cgi/content/full/37/7/489   (4140 words)

  
 Side effects of anticonvulsant medications
Since anticonvulsant medications decrease the intestinal absorption of calcium, individuals taking these medications are at increased risk of developing a calcium deficiency.
The majority of this vitamin’s supply is synthesised in the body by the "friendly" bacteria normally present in the intestine.
It is therefore vital that you discuss your unique needs with your health care professional.
http://www.angelfire.com/journal/GregoryJdeMontfort/SideEffectsofAnticonvulsantMedications.htm   (1856 words)

  
 Anticonvulsant monitoring in psychiatric practice -- Nelson and Gray 25 (9): 356 -- Psychiatric Bulletin
CHOONARA, L. and RANE, A. (1990) Therapeutic monitoring of anticonvulsants.
EADIE, M. (1995) The role of therapeutic drug monitoring in improving the cost effectiveness of anticonvulsant treatment.
MAIDMENT, I. (1999) Update on the use of new anticonvulsants as mood stabilisers.
http://pb.rcpsych.org/cgi/content/full/25/9/356   (1549 words)

  
 New This Month — The Family Health Guide
This study suggests birth defects are caused by anticonvulsant drugs and not by epilepsy itself.
However, the infants of mothers with epilepsy who were not treated with anticonvulsant drugs were at no greater risk of birth defects then infants of mothers without epilepsy.
A study published in the New England Journal of Medicine examined newborns for birth defects related to anticonvulsant drugs.
http://www.health.harvard.edu/fhg/NTMarchive/1101.shtml   (1670 words)

  
 Preclinical Evaluation of PNU-151774E as a Novel Anticonvulsant -- Fariello et al. 285 (2): 397 -- Journal of ...
Trimble MR and Cull C (1988) Children of school age: The influence of antiepileptic drugs on behavior and intellect.
Groups of at least 20 rats were used to assess the anticonvulsant activity at various time points.
Pellock JM (1994) Standard approach to antiepileptic drug treatment in the United States.
http://jpet.aspetjournals.org/cgi/content/full/285/2/397   (5024 words)

  
 Anticonvulsant drug use and low bone mass in adults with neurodevelopmental disorders -- Ray et al. 95 (4): 219 -- QJM
Fracture incidence and bone disease in epileptics receiving long-term anticonvulsant drug treatment.
represents a breakdown of the types of anticonvulsant
For the primary analysis, the association between anticonvulsant
http://qjmed.oxfordjournals.org/cgi/content/full/95/4/219   (2159 words)

  
 Anticonvulsant drugs for management of pain: a systematic review -- McQuay et al. 311 (7012): 1047 -- BMJ
of anticonvulsants used to treat pain produced by other drugs.
TABLE I--Reports of anticonvulsant drugs used for pain relief that were excluded from analysis ------------------------------------------------------------------------------------------------------------------------------------------------- Report Anticonvulsant Pain condition Reason for exclusion ------------------------------------------------------------------------------------------------------------------------------------------------- Arieff et al
Four anticonvulsant drugs were used: carbamazepine in 10 of
http://bmj.bmjjournals.com/cgi/content/full/311/7012/1047   (4421 words)

  
 Bipolar Disorder Treatment With Anticonvulsant Medication
Anticonvulsants work by calming hyperactivity in the brain in various ways.
Each anticonvulsant acts on the brain in slightly different ways, so your experience may differ depending on the drug you take.
Be sure to tell your doctor about any drugs, herbs, or supplements you take.
http://my.webmd.com/content/article/102/106786.htm   (380 words)

  
 U.S. Anticonvulsant Medications Markets: Indicated and Off-Label Uses
Meanwhile, "off-label" applications such as the treatment of chronic pain or bipolar disorder are generating important new opportunities for market participants.
"A number of second-generation anticonvulsants offer significant improvements in efficacy, tolerability, and ease of dosing for epileptics," says the analyst responsible for this study.
Although medications to treat epilepsy have been available for decades, significant advances in medical products and technologies have occurred only within the past five years.
http://www.mindbranch.com/catalog/print_product_page.jsp?code=R1-2044   (576 words)

  
 Practice parameter: Anticonvulsant prophylaxis in patients with newly diagnosed brain tumors: Report of the Quality ...
of anticonvulsant prophylaxis in some patients, it did not change
is no evidence that anticonvulsant prophylaxis is more effective
major concern, and the incidence and severity of anticonvulsant
http://www.neurology.org/cgi/content/full/54/10/1886   (3721 words)

  
 NEJM -- The Teratogenicity of Anticonvulsant Drugs
Antiepileptic drug therapy during pregnancy: the neurologist's perspective.
but took no anticonvulsant drugs during the pregnancy did not
those unexposed to anticonvulsant drugs but with a maternal
http://content.nejm.org/cgi/content/abstract/344/15/1132   (859 words)

  
 Finasteride, a 5alpha -Reductase Inhibitor, Blocks the Anticonvulsant Activity of Progesterone in Mice -- Kokate et al. ...
it can be concluded that the anticonvulsant mechanism of progesterone
the anticonvulsant activity of the metabolite, it seems unlikely
finasteride (up to 300 mg/kg) failed to affect the anticonvulsant
http://jpet.aspetjournals.org/cgi/content/full/288/2/679   (2985 words)

  
 Anticonvulsant Hypersensitivity Syndrome
Interim anticonvulsant therapy, as previously discussed, should be guided by avoiding similar or interactive antiepileptic drugs (Table 2).
Neurology, dermatology, and hematology- oncology consultants helped to point out controversial areas.
Certain anticonvulsant medications have a high degree of cross-reactivity, the incidence of AHS is higher among first-degree relatives, and the disorder mimics systemic infection.
http://www.familypractice.com/journal/2000/v13.n05/1305.07/art-1305.07.htm   (2500 words)

  
 Biophysical Journal: Continuum solvent model studies of the interactions of an anticonvulsant drug with a lipid bilayer
Continuum solvent model studies of the interactions of an anticonvulsant drug with a lipid bilayer
Despite extensive research, the flip-flop process is far from being clearly understood.
Recently, VPA has also been used for the treatment of other diseases, such as bipolar disorders and migraines (Loscher, 1999).
http://www.findarticles.com/p/articles/mi_qa3938/is_200106/ai_n8978798   (1093 words)

  
 Anticonvulsants
Anticonvulsant drugs are an important part of the treatment program for epilepsy.
Physicians may also prescribe certain anticonvulsant drugs for other conditions, including bipolar disorder (manic-depressive illness) and migraine headaches
Anticonvulsant drugs include such medicines as carbamazepine (Tegretol), phenytoin (Dilantin), and valproic acid (Depakote, Depakene).
http://www.psyweb.com/Glossary/anticon.jsp   (240 words)

  
 Anticonvulsant Medications, Hydantoin Derivatives
The effect of the anticonvulsants phenobarbital and diphenylhydantoin on intestinal absorption of calcium.
Elevated concentrations of homocysteine in antiepileptic drug treatment.
Calcium and folic acid absorption in patients taking anticonvulsant drugs.
http://www.metagenics.com/resources/imc/OneMedicineCons/ConsDepletions/AnticonvulsantMedicationsHydantoinDerivativescl.html   (791 words)

  
 University of Miami School of Medicine - Glossary - Anticonvulsant
Anticonvulsant drugs taken during pregnancy put the baby at risk of major birth defects -- growth retardation, microcephaly (a small head) and deformities of the face and fingers -- a condition known as anticonvulsant embryopathy.
There are a large number of anticonvulsant drugs today including, but not limited to: phenobarbital, phenytoin (Dilantin), carbamazepine, ethosuximide (Zarontin), clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and midazolam (Versed).
Anticonvulsant: A medication used to control (prevent) seizures (convulsions) or stop an ongoing series of seizures.
http://www.med.miami.edu/glossary/art.asp?articlekey=20523   (100 words)

  
 British Journal of Pharmacology - Abstract of article: The anticonvulsant actions of
The effects of caramiphen on I/O relationships mimicked those of the established anticonvulsant adenosine; in contrast, adenosine evoked an increase in PPF ratios.
Rather, anticonvulsant activity more likely reflects functional NMDA receptor antagonism and/or blockade of high voltage-activated Ca channels, effects which are associated with micromolar concentrations of the test compounds.
Modulation of GABAergic inhibitory mechanisms may also contribute to the anticonvulsant properties of caramiphen.
http://www.nature.com/bjp/journal/v124/n5/abs/0701902a.html   (422 words)

  
 Anticonvulsant, Anticonvulsants
Anticonvulsants speed up breakdown of vitamin K, leading to deficiency and bleeding.
Anticonvulsants may deplete biotin by competeing for absorption.
High levels of folate may increase breakdown of phenytoin (which may cause excess seizures)
http://www.naturdoctor.com/Chapters/Drugs/Anticonvulsant.html   (678 words)

  
 Anticonvulsant activity of GBR-12909 and citalopram characterized - Limbic Seizure : Epilepsy.com
For additional information, contact Y. Michotte, Free University of Brussels, Department of Pharmaceutical Chemistry, Drug Analysis and Drug Information, Experimental Pharmacology Research Group, Laarbeeklaan 103, B-1090 Brussels, Belgium.
Non-selective actions curtailing glutamatergic activity may further be responsible for the unexpected anticonvulsant effects at predicted proconvulsant concentrations.
Clinckers and colleagues published the results of their research in Neuropharmacology (Anticonvulsant action of GBR-12909 and citalopram against acute experimentally induced limbic seizures.
http://www.epilepsy.com/newsfeed/pr_1108132209.html   (403 words)

  
 Anticonvulsant and Antiretroviral Interactions -- Liedtke et al. 38 (3): 482 -- The Annals of Pharmacotherapy
Anticonvulsant and Antiretroviral Interactions -- Liedtke et al.
Clinical Assistant Professor, Department of Pharmacy, Clinical and Administrative Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, OK
: Limited data exist regarding interactions between anticonvulsant
http://www.theannals.com/cgi/content/abstract/38/3/482?etoc   (339 words)

  
 Dangerous Drug Eruptions--Anticonvulsant Hypersensitivity Syndrome
Onset of the anticonvulsant hypersensitivity syndrome is within 3 months of initiating therapy with dilantin (phenytoin), tegretol (carbamazepine), or phenobarbital.
The anticonvulsant hypersensitivity may present with a myriad of symptoms, among which are:
Do not rechallenge the patient with the suspected medication or related medications.
http://www.bu.edu/cme/modules/2002/drugerup02/content/4-hyper.htm   (313 words)

  
 Anticonvulsant - Wikipedia, the free encyclopedia
The benzodiazepines are a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and muscle relaxant properties.
Many typical anticonvulsants work by blocking voltage-sensitive sodium channels in the brain.
Barbiturates are drugs that acts as central nervous system (CNS) depressants, and by virtue of this they produce a wide spectrum of effects, from mild sedation to anesthesia.
http://en.wikipedia.org/wiki/Anticonvulsant   (293 words)

  
 Family Pratice News: Reevaluate Anticonvulsant Use In Pregnant Epilepsy Patients
Pregnant women with epilepsy who re main on anticonvulsant therapy may need an even higher dose of their medication.
Family Pratice News: Reevaluate Anticonvulsant Use In Pregnant Epilepsy Patients
Anticonvulsant drugs also lower serum folate level, probably by decreasing absorption, so these patients also may need extra folate, Dr. Niebyl told this newspaper.
http://www.findarticles.com/p/articles/mi_m0BJI/is_10_31/ai_76004522   (427 words)

  
 HON Mother & Child Glossary, Anticonvulsant Drugs and Pregnancy
Anticonvulsant therapy is associated with an increased risk of neural tube defects.
The babies of women treated with enzyme-inducing anticonvulsants (carbamazepine, phenytoin, primidone, phenobarbitone) are at increased risk of haemorrhagic disease of the newborn caused by deficiency of vitamin K-dependent clotting factors.
HON Mother & Child Glossary, Anticonvulsant Drugs and Pregnancy
http://www.hon.ch/Dossier/MotherChild/preg_drugs/anticonvulsants.html   (364 words)

  
 Anticonvulsant Effects of Coriandrum Sativum L. Seed Extracts in Mice
The mechanism of the anticonvulsant effect of C.
Coriander (vernacular Geshniz) seeds have been traditionally used in Iranian medicine for their carminative, diuretic and anticonvulsant effects.
Anticonvulsant and anti-inflammatory activity of natural plant coumarins and triterepenoids.
http://www.ams.ac.ir/AIM/0034/hosseinzadeh0034.html   (1256 words)

  
 Anticonvulsant lead compound identified - Drug Development : Epilepsy.com
Anticonvulsant lead compound identified - Drug Development : Epilepsy.com
Dimmock and colleagues published their study in the Journal of Enzyme Inhibition and Medicinal Chemistry (Anticonvulsants containing the N-(3-aryl-2-propenoyl) amido pharmacophore.
Molecular modeling was utilized in order to compare the positions of a phenyl ring in relation to amidic groups in representative compounds in series (1-3) with previously reported anticonvulsant agents, according to the report.
http://www.epilepsy.com/newsfeed/pr_1098451801.html   (378 words)

  
 Anticonvulsant Index page
Review of Epilepsy treatment - BMJ Jan 99
New antiepileptic drugs - review - Postgrad Med July 97
Choice of anticonvulsant in different type of seizures - BMJ Jan 99
http://neuroland.com/sz/anticon   (50 words)

  
 Merriam-Webster Online
For More Information on "anticonvulsant" go to Britannica.com
Get the Top 10 Search Results for "anticonvulsant"
http://www.m-w.com/cgi-bin/dictionary?book=Dictionary&va=anticonvulsant   (57 words)

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