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| | Anticoagulant Rodenticide Toxicosis in the Dog and Cat |
 | | Reports of natural anticoagulant rodenticide toxicosis are relatively common in dogs but have not been published concerning cats. | | | Signs of external hemorrhage such as melena, petechial to ecchymotic hemorrhage of mucosal surfaces, hyphema, hematamesis, epistaxis, and hematuria may or may not be apparent. | | | Mount M, Feldman B: Mechanism of diphacinone rodenticide toxicosis in the dog and its therapeutic implications. |
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http://www.vet.uga.edu/vpp/clerk/Harrell
(2490 words)
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| | LIPHATECH - Vet Guide |
| | Regardless of the anticoagulant involved, it is important to initiate therapy promptly. | | | Dodds and Frantz have been conducting research on poisoning of animals by anticoagulant rodenticides; the clinical data and recommendations reported here are drawn largely from their work. | | | The following case histories are representative of the range of dog poisoning incidents involving anticoagulants now being encountered and thus may be of use to veterinarians when designing treatment programs. |
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http://www.liphatech.com/vetguide.html
(5861 words)
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| | Anticoagulant rodenticides (EHC 175, 1995) |
| | The suggestion that the anticoagulant effect in rats is mediated by the unchanged compound itself rather than by its metabolites has been confirmed by the effects of phenobarbital and SKF525A pretreatments on the general pattern of responses to warfarin and brodifacoum (Bachmann & Sullivan, 1983). | | | There is no evidence to suggest that any anticoagulant rodenticides are mutagenic, but there are insufficient data available on individual compounds to demonstrate an absence of mutagenicity. | | | A distinction needs to be made between the characteristics of the technical compounds and those of their formulated products concerning the risks that their use poses to human health and the environment. |
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http://www.inchem.org/documents/ehc/ehc/ehc175.htm
(13782 words)
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| | Lupus Anticoagulant: The Test |
| | If someone tests positive for the lupus anticoagulant, the test may be done again in several weeks to see if the antibody was due to a temporary condition or is a chronic issue. | | | If possible, lupus anticoagulant testing should be done prior to the start of anticoagulation therapy. | | | Patients on heparin or heparin substitute (such as hirudin, danaparoid, or argatroban) anticoagulation therapy may have false-positive results for lupus antibodies but those on warfarin (coumadin) anticoagulant therapy should not. |
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http://www.labtestsonline.org/understanding/analytes/lupus_anticoagulant/test.html
(957 words)
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| | Lupus Anticoagulant Titration |
| | Exner, T., Richard, K. A., Kronenberg, H., A Sensitive Test Demonstrating Lupus Anticoagulant and its Behavioral Patterns. | | | Coumadin therapy, heparin therapy, factor deficiencies, for example, do not effect the endpoint determination. | | | ACS’s Spectra™ APCT shows good sensitivity to the lupus anticoagulant, factor VIII deficiency, Coumadin therapy and heparin therapy. |
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http://www.analyticalcontrols.com/LupTitr.htm
(600 words)
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| | Antiphospholipid Syndrome MEDSTUDENTS-RHEUMATOLOGY |
| | There are controversy between the relation of aCL and LA, thus the test may be positive for one, negative for other, or positive for all. | | | Both a primary form, in patients without clinically or serologically evident autoimune disorders, and a secondary form, usually in patients with systemic lupus erythematosus, are recognized. | | | Both lupus anticoagulant and anticardiolipin antibody are associated with each of the clinical manifestations of the antiphospholipid syndrome. |
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http://www.medstudents.com.br/reumat/reumat2.htm
(1042 words)
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| | Anticoagulant |
| | Germany provides much better health care support that us Americans have... | | | Generally, our practice involves the type of valve and other patient charateristics (ejection fraction, diabetes, etc..) in the descision how to manage a hiatus of anticoagulation. | | | Perhaps the reason that there are so few people self-testing in the US is that most doctors and medical people don't know of the point-of-care monitors, or have not had experience with them and therefore don't trust them. |
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http://www.medhelp.org/forums/cardio/messages/34583.html
(1053 words)
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| | Anti-Phospholipid Antibodies (Lupus Anticoagulant) |
| | All patients received 100 mg/d aspirin and 3,000 anti-Xa U/d certoparin. | | | To evaluate the use of intravenous immunoglobulin in RSA patients with APA and history of treatment failure, we initiated a study with standard therapy (aspirin and low-molecular-weight heparin) and intravenous immunoglobulin. | | | A total of 49 patients had positive APAs at the initial test, but were negative for ACA and lupus anticoagulant at the second test administered approximately 5 weeks after the start of therapy. |
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http://www.thedoctorsdoctor.com/diseases/antiphospholipid_antibody.htm
(5584 words)
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| | LONG ACTING ANTICOAGULANT RODENTICIDES |
| | Treatment consists of symptomatic and supportive therapy and vitamin Kl at a dose and for a duration of time based on the type of anticoagulant ingested and the response of the patient | | | More detailed discussions of the mechanisms, diagnosis, and therapy of anticoagulant rodenticide poisoning can be found in the references. | | | Treatment for all anticoagulant rodenticidetoxicoses is vitamin Kl with symptomatic and supportive treatment. |
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http://www.addl.purdue.edu/newsletters/1995/rodent.shtml
(530 words)
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| | AllRefer.com - anticoagulant (Pharmacology) - Encyclopedia |
| | Anticoagulants are used to treat blood clots, which appear especially frequently in veins of the legs and pelvis in bedridden patients. | | | Another anticoagulant, heparin, is a polysaccharide (see carbohydrate) found naturally in many cells. | | | They are only effective after the body's existing supply of prothrombin is depleted. |
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http://reference.allrefer.com/encyclopedia/A/anticoag.html
(260 words)
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| | Anticoagulant Therapy-Argatroban |
| | Argatroban is approved as anticoagulant therapy in patients who have or are at risk for HIT undergoing percutaneous coronary intervention (PCI). | | | When patients are at risk and heparin is no longer an option due to heparin-induced thrombocytopenia (HIT)... | | | Argatroban is the ONLY direct thrombin inhibitor approved for BOTH the prophylaxis and treatment of thrombosis associated with HIT. |
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http://www.argatroban.com
(120 words)
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| | Lupus Anticoagulant Reflex |
| | Lupus anticoagulants are nonspecific antibodies that extend the clotting time of phospholipid-dependent clotting assays such as the aPTT. | | | Unlike specific factor antibodies, LA are usually associated with venous thrombosis, pulmonary embolism, arterial thrombosis, and recurrent fetal loss. | | | Reagents with reduced amounts of phospholipid, such as the aPTT-LA and dilute Russell viper venom time (dRVTT), have enhanced sensitivity for LA. Due to the heterogeneity of LA antibodies, no single assay will identify all cases. |
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http://www.labcorp.com/datasets/labcorp/html/chapter/mono/cf000400.htm
(686 words)
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