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| Â | News - Women With Diarrhoea-Predominant Irritable Bowel Satisfied With Alosetron Therapy |
 | | Women With Diarrhoea-Predominant Irritable Bowel Satisfied With Alosetron Therapy | | | News - Women With Diarrhoea-Predominant Irritable Bowel Satisfied With Alosetron Therapy | | | The majority of alosetron-treated patients also approve the therapy when referring to the five specific medication attributes they consider most important, say researchers in the United States. |
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http://www.docguide.com/news/content.nsf/news/8525697700573E1885256C9700002ABA
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| Â | product_info |
| | A clinical interaction study was also conducted with alosetron and the CYP3A4 substrate cisapride. | | | The effect of induction or inhibition of individual pathways on metabolite kinetics and pharmacodynamic consequences has not been examined. | | | The effect on CYP1A2 was explored further in a clinical interaction study with theophylline and no effect on metabolism was observed. |
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http://www.fda.gov/cder/drug/infopage/lotronex/product_info.htm
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| Â | Is Alosetron An Effective Treatment For Irritable Bowel Syndrome? |
| | Alosetron is an example of this new class of drugs. | | | Forty-one percent of subjects in the alosetron group reported adequate relief of pain for all three months of treatment, this compared with 29% of the placebo group. | | | Although the results appear encouraging, only 12% more women in the alosetron group achieved satisfactory pain relief than in the placebo group. |
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http://www.arcmesa.com/cont_ed/mddigest/03-28-00.html
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| Â | MedlinePlus Drug Information: Alosetron (Systemic) |
| | Signing the agreement means that you understand the risks and benefits of alosetron therapy and that you have read and understand the Medication Guide. | | | Only doctors enrolled in the prescribing program for alosetron can write a prescription. | | | Mothers who are taking this medicine and who wish to breast-feed should discuss this with their doctor. |
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http://www.nlm.nih.gov/medlineplus/druginfo/uspdi/500107.html
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| Â | alosetron (oral) |
| | Continue to take alosetron and talk to your doctor if you experience | | | Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. | | | Your pharmacist has additional information about alosetron written for health professionals that you may read. |
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http://www.subscriberx.com/.SRX?Service=SRXLeaflet&Function=GetLeaflet&DrugId=31761&Dialect=English
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| Â | Alosetron Hydrochloride |
| | The exact relationship between this drug and acute colitis has not been determined. | | | Alosetron is effective as long as you continue to take the medication. | | | However, if you experience rectal bleeding or bloody diarrhea, low-grade fever, and abdominal distention and tenderness, discontinue alosetron and contact your doctor immediately. |
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http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,898,00.html
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| Â | DG DISPATCH - ACG: Alosetron Yields Relief In Non-Constipated Women With IBS |
| | Patients treated with alosetron (1 mg twice daily) for 12 weeks experienced a significant improvement in pain relief. | | | This side effect tended to occur in the first month of therapy, lasted approximately six days and tended not to recur. | | | A clear improvement over placebo was seen after one week of treatment. |
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http://www.pslgroup.com/dg/13c3ce.htm
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| Â | alosetron - Crohn's Disease: health and medical information about Crohns Disease and other digestive disorders |
| | Serotonin and its receptors in the intestines are believed to control how pain is felt (sensation), contraction of intestinal muscle, and release of fluid into the intestines. | | | In two, 12-week studies involving over 1,200 women, most of whom suffered from diarrhea-predominant IBS, 40% of the patients (or 40 out of every 100 patients) had adequate relief from abdominal pain and discomfort while taking alosetron. | | | PREGNANCY: There are no studies of alosetron in pregnant women. |
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http://www.medicinenet.com/alosetron/article.htm
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| Â | Alosetron: a case study in regulatory capture, or a victory for patients' rights? -- Moynihan 325 (7364): 592 -- BMJ |
| | November 1999: "We conclude there is no evidence for a causal relationship between the development of ischemic colitis and alosetron treatment" | | | The Food and Drug Administration's director of the Centre for Drug Evaluation and Research, Dr Janet Woodcock, strongly rejects | | | June 2000: "Our overall conclusion is that ischemic colitis appears more frequently than at least was recognized by us"; the company emphasised that the harm is "acute, transient and self-limiting" |
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http://bmj.com/cgi/content/full/325/7364/592
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| Â | Role of serotonin in the pathophysiology of the irritable bowel syndrome -- Crowell 141 (8): 1285 -- British Journal of ... |
| | CAMILLERI, M. and PRATHER, C.M. The irritable bowel syndrome: mechanisms and a practical approach to management. | | | BARDHAN, K.D., BODEMAR, G., GELDOF, H., SCHUTZ, E., HEATH, A., MILLS, J.G. and JACQUES, L.A. A double-blind, randomized, placebo-controlled dose-ranging study to evaluate the efficacy of alosetron in the treatment of irritable bowel syndrome. | | | BEARCROFT, C.P., ANDRE, E.A. and FARTHING, M.J. In vivo effects of the 5-HT antagonist alosetron on basal and cholera toxin-induced secretion in the human jejunum; as segmental perfusion study. |
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http://www.brjpharmacol.org/cgi/content/full/141/8/1285
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| Â | Incidence of colonic ischemia, hospitalized complications of constipation, and bowel surgery in relation to use of ... |
| | The incidence rates were essentially the same in alosetron users (1.24/1000 person-yr) and in IBS patients with no alosetron use (0.92/1000 person-yr). | | | Thirty instances of bowel surgery occurred, giving rates of 10.2/1000 person-yr in the alosetron cohort and 11.8/1000 person-yr in the IBS/no alosetron cohort. | | | CONCLUSIONS: Alosetron users did not differ from IBS patients not using alosetron in the incidence of bowel surgery or hospitalized complications of constipation; there were no cases of colonic ischemia. |
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http://currentinsurance.com/ref-insurance-7/insurance-7-research-abs3.228.html
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| Â | alosetron |
| | Click here to request further information on Drug News | | | Lead Story from Drug News, 26 June 2002 | | | The product is to be remarketed for use in women with severe diarrhea-predominant IBS who have failed to respond to conventional therapy, whose IBS symptoms are chronic and who have had other gastrointestinal medical conditions that could explain their symptoms. |
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http://www.ims-global.com/insight/drugs_news/0206/drug_news_020626.htm
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| Â | Irritable Bowel Syndrome Symptoms Signs - Natural Treatments |
| | Alosetron hydrochloride (Lotronex) has been re-approved by the U.S. Food and Drug Administration (FDA) for women with severe Irritable Bowel Syndrome who have not responded to conventional therapy and whose primary symptom is diarrhea. | | | However, even in these patients, it should be used with caution because it can have serious side effects, such as severe constipation or decreased blood flow to the colon. |
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http://www.heartspring.net/irritable_bowel_syndrome.html
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| Â | Lotronex |
| | The committee discussed risk management for new drug application (NDA) 21-107, Lotronex (alosetron), GlaxoSmithKline. | | | FDA announced June 7, 2002 the approval of a supplemental New Drug Application (sNDA) that allows restricted marketing of Lotronex (alosetron hydrochloride), to treat only women with severe diarrhea-predominant irritable bowel syndrome (IBS). | | | The approved sNDA for Lotronex includes a risk management program to ensure patients and physicians are fully informed of risks and possible benefits of Lotronex. |
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http://www.fda.gov/cder/drug/infopage/lotronex/lotronex.htm
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| Â | Pharmacy: Drugs and Medications: A: Alosetron Treasure Coast Health |
| | Lotronex (Alosetron HCI) - GSK - Official pharmaceutical website with information for patients and care givers. | | | Lotronex Information - FDA - Includes information for patients and care givers with links to current (re-released)product information and information about the previous withdrawal from the market in 2000. | | | Brand name drugs we sell include Lipitor, Nexium & Prevacid. |
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http://www.tchealth.com/Resources-Health/Pharmacy/Drugs_and_Medications/A/Alosetron/
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| Â | Alosetron |
| | Official pharmaceutical website with information for patients and care givers. | | | Starware search is an excellent resource for quality sites on alosetron and much more! | | | Find the Best Sites For alosetron With Starware |
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http://haxwax-rx.com/Alosetron.html
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