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| | Recombinant Human Alanine Aminotransferase (ALT/SGPT) - ENZ-280 |
 | | The associations of physical activity and adiposity with alanine aminotransferase and gamma-glutamyltransferase. | | | Relationship between serum alanine aminotransferase levels and liver histology in chronic hepatitis C-infected patients. | | | Strenuous physical labor is important as a cause of elevated alanine aminotransferase levels in Japanese patients with chronic hepatitis C viremia. |
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http://www.prospec.co.il/~prospec/cart/catalog/rALT.html
(368 words)
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| | International Conference on Psychophysiology of Panic Attacks |
| | There were significant differences between Aspartate transaminase, alanine transaminase and alkaline phosphatase just before examination when compared to relaxed state. | | | This study examines the influence of examination stress during panic situation, on Aspartate transaminase, Alanine transaminase and alkaline phosphatase among students. | | | These normally serve us well but when things are starting to get out of control they can have a tendency to get into a feedback cycle. |
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http://anxiety-panic.com/conference/c004ah.cfm
(302 words)
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| | ALT - Hepatitis C News Articles |
| | Liver Transaminase Changes in HIV-HCV Coinfected Antiretroviral-naïve Patients Treated with Tenofovir Versus Stavudine | | | Anti-TNF Therapy May Be Safe for Patients with Hepatitis C | | | Liver Histology and Alanine Aminotransferase Levels in Children and Adults with Chronic Hepatitis C Infection |
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http://www.hivandhepatitis.com/hep_c/hepc_news_alt.html
(591 words)
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| | Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine ... |
| | Exploratory analysis using stepwise modeling revealed that HBeAg seroconversion correlated highly with pretherapy ALT (P <.001) followed by lamivudine therapy (P =.013), but only marginally with baseline HBV-DNA (P =.071) and cirrhosis (P =.066) for lamivudine 100 mg and placebo comparison. | | | Pretherapy alanine transaminase level as a determinant for hepatitis B e antigen seroconversion during lamivudine therapy in patients with chronic hepatitis B. Asian Hepatitis Lamivudine Trial Group. | | | These results suggest that pretherapy ALT is the strongest determinant for HBeAg seroconversion during lamivudine therapy, and should be considered in selecting patients for treatment. |
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http://www.aegis.com/aidsline/1999/nov/A99B0398.html
(561 words)
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| | Adult Health Advisor 2005.2: Blood (Serum) Glutamate Pyruvate Transaminase (SGPT) Test |
| | You should speak to your physician or make an appointment to be seen if you have questions or concerns about this information or your medical condition. | | | This information is approved and/or reviewed by U-M Health System providers but it is not a tool for self-diagnosis or a substitute for medical treatment. | | | This enzyme is found in many body tissues in small amounts, but it is very concentrated in the liver. |
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http://www.med.umich.edu/1libr/aha/aha_sgpt_crs.htm
(541 words)
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| | AACE: Studies Reveal Good News Regarding Liver Safety of Pioglitazone |
| | "Our studies show that PIO decreases in normal levels of transaminase and bilirubin, so we don't have the same risk and, in all these studies, there were very little liver problems," says Frederick T. Murray, MD, Director of Medical affairs, Takeda Pharmaceuticals North America, Inc. Dr. | | | In contrast, continuing studies of PIO show reductions of alanine transaminase levels in the overwhelming majority of type 2 patients. | | | Murray is an author of 3 of the studies presented at the American Association of Clinical Endocrinologists 12th Annual Meeting and Clinical Congress,May 14 — 18, San Diego, Calif. |
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http://www.pslgroup.com/dg/233352.htm
(504 words)
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| | Bioline International Official Site (site up-dated regularly) |
| | All parameters were analyzed using one-way analysis of variance (ANOVA) while the differences between treatment groups were tested using the Scheffe multiple comparison method with 0.05 representing the level of significance. | | | Determination of serum aspartate and alanine transaminases (AST, ALT), alkaline phosphatase (ALP) and bilirubin | | | The biochemical parameters like alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP) and also total and conjugated bilirubin were measured. |
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http://www.bioline.org.br/request?ph04102
(1453 words)
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| | Intestinal Mucosal Amino Acid Catabolism -- Wu 128 (8): 1249 -- Journal of Nutrition |
| | Methionine transamination occurs in small intestinal homogenates (Mitchell and Benevanga 1978), and glutamine transaminase | | | Alanine is an important nitrogenous product of the intestinal catabolism of glutamine, glutamate, aspartate (Windmueller 1982 | | | of phenylalanine transaminase activity in the isoenzymes of aspartate |
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http://www.nutrition.org/cgi/content/full/128/8/1249
(4020 words)
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| | UEGW: Clevudine Potent and Well Tolerated Against Hepatitis B Virus |
| | Hyo-Suk Lee, MD, principal investigator, professor of internal medicine, Department of Internal Medicine, and Liver Research Institute, Seoul National University Hospital, Seoul, South Korea, presented the multicentre, randomised, double-blind, placebo-controlled, phase 2 clinical study. | | | [Presentation title: "A 12-week Clevudine Therapy Showed Durable Antiviral Activity and Normalization of Alanine Transaminase Levels for 6 Months After Discontinuation of Treatment in Patients with Chronic Hepatitis C. Abstract OP-G-84." Abstract 544] | | | PRAGUE, CZECH REPUBLIC -- September 29, 2004 -- The pyrimidine nucleoside analogue clevudine is well tolerated and shows potent antiviral activity against hepatitis B virus (HBV), with durable viral suppression and sustained normalization of alanine transaminase (ALT) levels, according to results of a trial presented here September 27th at the 12th United European Gastroenterology Week. |
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http://www.docguide.com/dg.nsf/PrintPrint/545386A68BB373FF85256F1E006A019A
(693 words)
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| | Responses - Alanine Transaminase and ALS |
| | She has been told that she cannot receive the treatment of choice due to her level of alanine transaminase which is 56. | | | Alanine transaminase is an enzyme that is located both in liver and in muscle and can be elevated in diseases that effect either. | | | Because there is muscle deterioration in ALS, alanine transaminase levels can be elevated in this disease. |
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http://www.mdausa.org/experts/question.cfm?id=1069&disease=66
(208 words)
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| | alanine on Encyclopedia.com |
| | Glutamine and Alanine Kinetics in Humans: Role of the Liver. | | | Daily interferon monotherapy for chronic hepatitis C in patients with normal or nearnormal serum alanine transaminase levels: a comparison of two protocols.(Original Article) | | | Prospective study of the association between the proline to alanine codon 12 polymorphism in the PPAR[gamma] gene and type 2 diabetes.(Pathophysiology/Complications) |
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http://www.encyclopedia.com/html/a1/alanine.asp
(511 words)
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| | Common Liver Function Tests |
| | This test may be performed to assess liver function, and/or to evaluate treatment of acute liver disease, such as hepatitis. | | | This test measures the level of aspartate transaminase (an enzyme that is found in the liver, kidneys, pancreas, heart, skeletal muscle, and red blood cells) that is released into the bloodstream after liver or heart problems. | | | This test measures the level of alanine aminotransferase (an enzyme found predominantly in the liver) that is released into the bloodstream after acute liver cell damage. |
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http://www.healthsystem.virginia.edu/uvahealth/adult_liver/tests.cfm
(497 words)
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| | Amino Acid Metabolism |
| | Alanine is transferred to the circulation by many tissues, but mainly by muscle, in which alanine is formed from pyruvate at a rate proportional to intracellular pyruvate levels. | | | Alanine's catabolic pathway involves a simple aminotransferase reaction that directly produces pyruvate. | | | There are 2 main pathways to production of muscle alanine: directly from protein degradation, and via the transamination of pyruvate by alanine transaminase, ALT (also referred to as serum glutamate-pyruvate transaminase, SGPT). |
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http://web.indstate.edu/thcme/mwking/amino-acid-metabolism.html
(3753 words)
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| | Liver Function Tests |
| | Alanine transaminase is an enzyme that plays a role in processing proteins, and it's found in the liver, heart, muscles, and kidneys. | | | Aspartate transaminase is an enzyme that plays a role in metabolism, the process that converts the fuel from food into energy the body needs. | | | These tests can help a doctor diagnose viral infections (like mononucleosis or viral hepatitis) or any sort of liver damage from other health problems. |
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http://kidshealth.org/parent/general/sick/labtest6.html
(459 words)
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| | ALT |
| | ALT is present in many different kinds of tissue in the body. | | | ALT is an enzyme that takes part in the metabolism (chemical processing by the body) of the amino acid, alanine. | | | This test determines the level of the enzyme alanine transaminase (ALT) in the blood. |
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http://www.northmemorial.com/HealthEncyclopedia/content/1031.asp
(306 words)
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| | Aspartate transaminase - Wikipedia, the free encyclopedia |
| | It is also present in red cells and cardiac muscle. | | | Aspartate transaminase (AST) also called Serum Glutamic Oxaloacetic Transaminase (SGOT) or aspartate aminotransferase (ASAT) (EC 2.6.1.1) is similar to alanine transaminase (ALT) in that it is another enzyme associated with liver parenchymal cells. |
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http://en.wikipedia.org/wiki/Aspartate_transaminase
(69 words)
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| | Process and reagent for the determination of transaminase - Patent 4728604 |
| | The determination of the GOT is also used for diagnosis of diseases of the heart muscles. | | | A process as in claim 1 wherein said transaminase is glutamate-oxalacetate-transaminase, and said amino acid is aspartate, wherein said process further comprises adding malate dehydrogenase to said sample. | | | A process as in claim 1, wherein said transaminase is glutamate-pyruvate-transaminase, and said amino acid is alanine. |
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http://www.freepatentsonline.com/4728604.html
(1977 words)
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| | [No title] |
| | This reaction is rather interesting because Glutamate Dehydrogenase may use NAD or NADP as a coenzyme. | | | Alanine may diffuse out of the extrahepatic tissue, into the Hepatocytes. | | | Alanine may then transfer the Nitrogen to an (-KG. |
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http://people.musc.edu/~neilseea/biochem/aametab.doc
(788 words)
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| | Toxicity With Selective Serotonin Reuptake Inhibitors -- SOLOMONS et al. 162 (6): 1225 -- American Journal of Psychiatry |
| | Investigations demonstrated elevated levels of liver enzymes: alanine transaminase, 378 µmol/liter (her level at admission was 26 µmol/liter); aspartate transaminase, 609 µmol/liter (her level at admission was 11 µmol/liter); lactic hydrogenase, 850 µmol/liter (her level at admission was 101 µmol/liter); and serum creatinine, 763 µmol/liter (her level at admission was 66 µmol/liter). | | | Epigastric and right upper quadrant pain developed after 4 days of citalopram use, with the liver enzyme aspartate transaminase rising from 34 to 251 µmol/liter and alanine transaminase from 94 to 282 µmol/liter. | | | Liver enzyme levels decreased with fluvoxamine discontinuation but increased within 4 days of rechallenge, from an alanine transaminase level of 208 to 379 µmol/liter and an aspartate transaminase level of 121 to 181 µmol/liter. |
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http://ajp.psychiatryonline.org/cgi/content/full/162/6/1225
(539 words)
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| | Dorlands Medical Dictionary |
| | Called also alanine aminotransferase and glutamic-pyruvic transaminase (GPT). | | | The enzyme can also act on γ-aminobutyrate and S-β-aminoisobutyrate; it has been listed as a secondary activity of the enzyme 4-aminobutyrate transaminase but may be a separate enzyme. | | | Serum enzyme activity (SGPT) is greatly increased in liver disease and also elevated in infectious mononucleosis. |
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http://www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspzQzpgzEzzSzppdocszSzuszSzcommonzSzdorlandszSzdorlandzSzdmd_a_21zPzhtm
(1370 words)
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| | Amino acid degradation |
| | These two enzymes, alanine transaminase and aspartate transaminase, are also important in the diagnosis of heart attacks and liver diseases. | | | Therefore, elevated levels of alanine transaminase and aspartate transaminase in the serum are indicative of liver or heart damage. | | | Under these disease conditions, these enzymes "leak" into the serum from damaged cells. |
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http://www.db.uth.tmc.edu/faculty/faculty/alevine/1521_2000/aadeg.htm
(811 words)
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| | dializedabs abstract |
| | O, resulted in a gradual decline in the enrichment of alanine from albumin, while the enrichments in plasma free alanine and body water were negligible. | | | Enrichment of alanine from plasma albumin gradually increased, with again ~80 to 100% as much | | | Thus, presumably due to the action of alanine transaminase, there is a rapid exchange, essentially complete, between the hydrogens of the amino acid and the hydrogens of body water. |
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http://www.cwru.edu/artsci/math/alexander/abstracts/dializedabs.html
(228 words)
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| | Diclofenac hepatitis -- Purcell et al. 32 (11): 1381 -- Gut |
| | transaminase and alanine transaminase activity of up to 30 to 40 times the | | | alanine transaminase for the group was exponential, with half lives of | | | The average total dose taken by 18 patients for whom |
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http://gut.bmjjournals.com/cgi/content/abstract/32/11/1381
(414 words)
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| | Contig916 |
| | pirA39900 alanine transaminase (EC 2.6.1.2) - rat 195 4e-49 | | | To make a new and actualized BLAST analysis click on Blast it now in accord to the database desired. | | | Click on BLASTs to see the data used in our annotation, data from 04/2002. |
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http://www.icb.ufmg.br/~lgb/schisto/Contig916.htm
(83 words)
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| | Amino Acid Synthesis |
| | There are at least 3 different fates of alanine all of which are the removal of the amine to become pyruvate. | | | Required cofactors: Zn Vitamin deficiencies blocking this reaction: Niacin |
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http://www2.canisius.edu/~corsot/biochemistry/amino_acid_catabolism.htm
(607 words)
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| | HEPATIC EFFECTS OF AMIODARONE ARE BEST CORRELATED WITH MONITORING ALANINE TRANSAMINASE* |
| | Purpose: Study the relationship between markers of hepatic function and serum concentrations of the antiarrhythmic agent, amiodarone (AMIO) and its active metabolite, desethylamiodarone (DEA). | | | Methods: Hepatic transaminases, alkaline phosphatase, bilirubin, albumin, total protein, were measured at baseline and regularly in 51 patients receiving AMIO for at least 24 mo. Subclinical hepatotoxicity was defined as alanine (ALT) or aspartate transaminase (AST) > twice upper limit of normal for at least 2 consecutive recordings. | | | HEPATIC EFFECTS OF AMIODARONE ARE BEST CORRELATED WITH MONITORING ALANINE TRANSAMINASE* |
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http://www.ccs.ca/society/congress2001/abstracts/abs/a404.htm
(178 words)
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| | Tables |
| | Normal values: alanine transaminase, 0-35 units/ L; aspartate transaminase, 0-35 units/L; alkaline phosphatase, 30-114 units/L; lactate dehydrogenase, 118-242 units/L; total bilirubin, <1.2 mg/dL; direct bilirubin, <0.2 mg/dL; | | | Alanine transaminase (units/L) & transaminase (units/L)  & (units/L) Lactate dehydrogenase (units/L) b | | | Alanine transaminase (units/L) & transaminase (units/L)  & (units/L) Total bilirubin (mg/dL) |
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http://www.medscape.com/content/2002/00/44/02/440227/440227_tab.html
(152 words)
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| | [No title] |
| | 1092 : Q9S7E9_ARATH 0.30 0.28 779 1170 10 467 389 10 72 481 Q9S7E9 Putative alanine aminotransferase; 63135- 1093 : Q881G8_PSESM 0.30 0.36 780 1165 7 395 376 6 23 402 Q881G8 Aspartate aminotransferase. | | | 977 : Q9C5K2_ARATH 0.31 0.29 404 776 30 467 370 9 71 481 Q9C5K2 Putative alanine aminotransferase. | | | 980 : Q9C5K2_ARATH 0.31 0.29 16 388 30 467 370 9 71 481 Q9C5K2 Putative alanine aminotransferase. |
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http://www.infobiogen.fr/db/hssp/1xi9.hssp
(15924 words)
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| | ALT - TheBestLinks.com - Liver, NASA, Space Shuttle, 1976, ... |
| | ALT is an abbreviation for alanine transaminase, an enzyme in the liver. | | | ALT is also the name of a band, the members of which are Andy White (Irish Musician), Tim Finn and Liam O'Maonlai. | | | ALT, Liver, NASA, Space Shuttle, 1976, Telomere, Alanine transaminase... |
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http://www.thebestlinks.com/ALT.html
(213 words)
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| | EC 2.6.1.44 |
| | A second component also catalyses the reaction of EC 2.6.1.51 serine—pyruvate transaminase. | | | With one component of the animal enzyme, 2-oxobutanoate can replace glyoxylate. |
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http://www.chem.qmw.ac.uk/iubmb/enzyme/EC2/6/1/44.html
(85 words)
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| | Exam 3 - 1995 |
| | Enzymes that incorporate free ammonia into forms useful for the central pathways of amino acid metabolism include A. aspartate transaminase and alanine transaminase B. carbamoyl phosphate synthase II and adenosine deaminase C. alpha-ketoglutarate aminotransferase and phosphoserine transaminase D. glutamine synthetase and glutamate dehydrogenase E. phenylalanine hydroxylase and cystathionase 2. | | | On the answer sheet, mark the one which is best in each case. | | | The primary function of the urea cycle is A. to convert toxic ammonia to urea which can be excreted B. the turnover of excess arginine C. the production of the citric acid cycle intermediate fumarate D. the synthesis of ornithine for spermidine synthesis E. the synthesis of aspartate 3. |
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http://www.usd.edu/med/som/somdept/biochem/courses/bioc520/b520e3.htm
(912 words)
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| | Proteases and Transaminases-Rockland Immunochemicals |
| | Anti-ASPARTATE TRANSAMINASE (AST) (Pig Heart) (Sheep) Biotin Conjugated | | | Anti-ASPARTATE TRANSAMINASE (AST) (Pig Heart) (Sheep) Peroxidase Conjugated | | | Anti-ALANINE TRANSAMINASE (ALT) (Pig Heart) (Sheep) Biotin Conjugated |
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http://www.rockland-inc.com/ccc1149-proteases-and-transaminases.htm
(56 words)
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| | [No title] |
| | For 17 AA: amino groups transferred to Glutamic Acid, or broken down to Glutamic acid transaminated with pyruvate AA amino group Glutamic Acid Alanine 2. | | | Serine synthesis: (3-Phospho Glyceric Acid (keto acid (Serine) Glutamic Acid Dehydrogenase + transaminase Phosphotase NAD + B6 H20 3 PGA (3 Phospho 3 POH pyruvate NADH 3P Serine Serine Glyceric Acid) (keto acid) 3. |
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http://www.uhmc.sunysb.edu/som/students/2002/2002Web/Lectures/Cells/cells32.doc
(126 words)
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| | EC 2.6.1.2 |
| | Wilson, D.G., King, K.W. and Burris, R.H. Transaminase reactions in plants. | | | -alanine-a-ketoglutarate aminotransferase; pyruvate transaminase; pyruvate-alanine aminotransferase; pyruvate-glutamate transaminase | | | Green, D.E., Leloir, L.F. and Nocito, W. Transaminases. |
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http://www.chem.qmw.ac.uk/iubmb/enzyme/EC2/6/1/2.html
(120 words)
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