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| | Caffeine, caffeine withdrawal, adenosine, and primary headache |
 | | BACKGROUND: Caffeine is an adenosine antagonist used as a headache and migraine medicine. | | | 24 And adenosine causes localized pain and vasodilation when applied topically to the skin,25 which is one reason Burnstock proposed that adenosine triphosphate (ATP) and adenosine may cause the pain and vasodilation associated with migraine. | | | That would readily explain the major symptoms of primary headache (headache and nausea/vomiting), the high prevalence of primary headache, the irregularly episodic nature of primary headache, and the ability of caffeine to abort primary headache, and may explain many other symptoms and aspects of primary headache as well. |
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http://www.batnet.com/spencer/theory.html
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| | Science News Online - This Week - News Feature - 5/24/97 |
| | The new adenosine research may bolster a recent theory that the body's regular desire for sleep stems from the brain's periodic need to replenish low stores of energy. | | | Since the sleeping brain is much less active than the waking one, sleep allows the organ to replenish its energy, they proposed. | | | We predicted what they got," says Miodrag Radulovacki of the University of Illinois College of Medicine in Chicago, the earliest champion of the adenosine theory of sleep. |
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http://www.sciencenews.org/sn_arc97/5_24_97/fob2.htm
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| | Adenosine news articles |
| | Caffeine dampens the neurotransmitter adenosine, which acts as a calming and mildly pain-relieving force upon the body. | | | A drug called Adenosine is used to "trick" the body into thinking it is exercising. |
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http://www.mongabay.com/drugs/drugs/Adenosine.html
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| | Adenosine Monophosphate, AMP |
| | Adenosine is a sensitive oxygen sensor in the heart. | | | Endogenous adenosine improves work rate to oxygen consumption ratio in catecholamine stimulated isovolumic rat heart. | | | Adenosine monophosphate (AMP) has been used in connection with the following conditions (refer to the individual health concern for complete information): |
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http://www.truestarhealth.com/Notes/2796008.html
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| | Adenosine A2B Receptors -- Feoktistov and Biaggioni 49 (4): 381 -- Pharmacological Reviews |
| | Adenosine is an endogenous nucleoside that modulates many physiological processes. | | | Whereas most studies of the cardiovascular effects of adenosine have focused on its acute actions on vascular tone and adrenergic | | | Schematic representation of intracellular pathways coupled to adenosine A |
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http://pharmrev.aspetjournals.org/cgi/content/full/49/4/381
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| | Adenosine And Sleep |
| | Some researchers now are determining whether sleep relates back to ATP by examining the relationship between adenosine and ATP on a cellular level. | | | This suggested that adenosine plays a role in sleep. | | | Other scientists are investigating ways to manipulate adenosine to treat sleep disorders. |
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http://www.sfn.org/content/Publications/BrainBriefings/adenosine.html
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| | Adenosine for fast heart rates - [Medication] |
| | Adenosine is always given by a health professional while you are hooked up to a heart monitor. | | | Adenosine is a quick-acting, short-term therapy intended to convert the fast heart rhythm of a supraventricular tachycardia (SVT) that affects the AV node back to a normal rate. | | | Adenosine can be very effective at slowing or ending a rapid heart rate if the problem is caused by an abnormal electrical pathway in the heart. |
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http://www.peacehealth.org/kbase/topic/detail/drug/ps1324/detail.htm
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| | InterPro: IPR001634 Adenosine receptor |
| | The physiological role of adenosine is thought to be to adjust energy demands in line with oxygen supply. | | | Many of the clinical actions of methylxanthines are thought to be mediated through antagonism of adenosine receptors. | | | In the CNS, adenosine exerts a pre- and post-synaptic depressant action, reducing motor activity, depressing respiration, inducing sleep and relieving anxiety. |
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http://www.ebi.ac.uk/interpro/IEntry?ac=IPR001634
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| | Adenosine triphosphate - Wikipedia, the free encyclopedia |
| | In signal transduction pathways, ATP is used to provide the phosphate for the protein-kinase reactions. | | | For other uses of the initials ATP, see ATP (disambiguation) | | | ATP consists of adenosine and three phosphate groups(triphosphate). |
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http://en.wikipedia.org/wiki/Adenosine_triphosphate
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| | Adenosine Molecule |
| | antiarrhythmic agent.The pharmacological effects of adenosine are blunted in individuals who are taking | | | Adenine forms adenosine, a nucleoside, when attached to ribose, and deoxyadenosine when attached to deoxyribose, and it forms adenosine triphosphate (ATP), a nucleotide, when three phosphate groups are added to adenosine. | | | Adenosine triphosphate is used in cellular metabolism as one of the basic methods of transferring chemical energy between reactions. |
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http://www.worldofmolecules.com/life/adenine.htm
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| | Adenosine |
| | Methylxanthines (for example, caffeine and theophylline) antagonize the action of adenosine. | | | Adenosine is the drug of choice for paroxysmal supraventricular tachvcardia (PSVT) and can be used diagnostically for stable, wide complex tachyardias of unknown type after two doses of lidocaine. | | | Dipyridamole potentiates the effect of adenosine; reduction of adenosine dose may be required. |
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http://www.randylarson.com/acls/drugs/adenosine.html
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| | PART5 |
| | Patients receiving theophylline or caffeine may not respond to adenosine therapy. | | | Adenosine has a half-life of approximately 10 seconds. | | | It is useful for the treatment of paroxysmal supraventricular tachycardia (PSVT) associated with accessory bypass tracts (Wolf-Parkinson-White syndrome). |
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http://rems.vaems.org/Protocols/Part5.HTML
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| | Adenosine triphosphate definition - Medical Dictionary definitions of popular medical terms |
| | Adenosine triphosphate definition - Medical Dictionary definitions of popular medical terms | | | Adenosine triphosphate: An important carrier of energy in cells in the body and a compound that is important in the synthesis (the making) of RNA. | | | The body produces ATP from food and then ATP produces energy as needed by the body. |
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http://www.medterms.com/script/main/art.asp?articlekey=6582
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| | Adenosine Therapeutics |
| | Adenosine Therapeutics Announces Initiation of Phase III Clinical Trials | | | Adenosine Therapeutics Announces Collaboration with Ortho-McNeil Pharmaceutical, Inc. to Develop Novel Oral Drugs for Diabetes and Asthma |
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http://www.adenrx.com
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| | Age-related changes in cardiac adenosine receptor expression. |
| | Subsequently, relative analysis of the adenosine receptor subtypes using 18S rRNA found a significant age-related reduction in the expression of the adenosine A(1) receptor (5.5-fold), with no changes in the expression of the adenosine A(2A), A(2B) and A(3) receptors. | | | Absolute quantification showed that no age-related changes occurred in the expression of 18S rRNA or adenosine A(2B) receptor internal control genes. | | | It is well established that functional responses to adenosine decline with age. |
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http://www.arclab.org/medlineupdates/abstract_15013665.html
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| | adenosine |
| | Doug Markham of the Institute for Cancer Research, Fox Chase Cancer Center,Philadelphia, PA, has contributed the following structure for adenosine. | | | Doug Markham has contributed a molecular mechanics computation of the structure! | | | He computed this structure in sdf format using MacroModel, a molecular mechanics program. |
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http://www.biocheminfo.org/klotho/html/adenosine.html
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| | NDI Terminology - adenosine |
| | adenosine triphosphate - A nucleotide involved in energy metabolism and required for RNA synthesis; it occurs in all cells and is used to store energy in the form of high-energy phosphate bonds. | | | adenosine monophosphate - A nucleotide involved in energy metabolism. | | | It is a component of ribonucleic acid and its nucleotides play major roles in the reactions and regulation of metabolism. |
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http://www.ndif.org/Terms/adenosine.html
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| | Medcyclopaedia - Adenosine |
| | It is considered to be a mediator of metabolically induced vasodilatation by acting upon adenosine receptors on vascular smooth muscle cells. | | | Adenosine is used to induce regional blood flow imbalance in the presence of a haemodynamically significant coronary arterial stenosis. | | | It serves as one of several pharmacological stress agents for radionuclide perfusion imaging for the detection of haemodynamically significant obstructive disease of the coronary arteries. |
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http://www.medcyclopaedia.com/library/topics/volume_v_2/a/ADENOSINE.aspx
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