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| | Tribulus terrestris & Protodioscin Study - Acrosome Reaction & Sperm Motility |
 | | There was, however, a considerable difference in the proportion of live spermatozoa with normal acrosome in the treated group, as compared to the control. | | | Evaluation of the acrosome in oligozoospermic subjects by simplified triple stain technique. | | | The general goal of this study is to evaluate the use of Tribulus terrestris L. as a medical treatment of oligoasthenoteratozoospermia, with specific goals of the following: |
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http://www.libilov.com/en/clinical_studies/study_Setiawan_1996.htm
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| | Guanylate Cyclase Activity and Sperm Function -- Revelli et al. 23 (4): 484 -- Endocrine Reviews |
| | Anderson RA, Feathergill KA, Drisdel RC, Rawlins RG, Mack SR, Zaneveld LJ 1994 Atrial natriuretic peptide (ANP) as a stimulus of the human acrosome reaction and a component of ovarian follicular fluid: correlation of follicular ANP content with in vitro fertilization outcome. | | | NO) strongly affect sperm motility, capacitation, and acrosomal | | | Benoff S 1998 Modelling human sperm-egg interactions in vitro: signal transduction pathways regulating the acrosome reaction. |
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http://edrv.endojournals.org/cgi/content/full/23/4/484
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| | Mammalian acrosome reaction |
| | This would suggest that neither pathway is sufficient and that the combined products of both pathways are critical for generating the acrosome response. | | | Perhaps the most well studied case concerns the degranulation of histamine granules in our bodies' mast cells that is responsible for allergic reactions. | | | So while the pathways within the sperm leading to the acrosome's exocytosis are accounted for, the initial receptor reaction is still controversial. |
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http://zygote.swarthmore.edu/fert5.html
(889 words)
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| | UNSW Embryo- Acrosome OMIM ENTRY 102530 |
| | The fact that about half the early spermatids lacked the acrosome granule suggested that the original cause is genetic and that the gene is expressed in the haploid phase. | | | (1983) found that the round-headed spermatozoa of an infertile patient with globozoospermia lacked the constituting components of the outer acrosomal membrane as well as the intraacrosomal acrosin system (see 102480). | | | (1977) observed acrosome malformations of spermatids and spermatozoa in the testes of 2 infertile males who were investigated by light and electron microscopy. |
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http://embryology.med.unsw.edu.au/OMIMfind/fert/102530.htm
(534 words)
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| | Acrosome Reaction Animation |
| | The Ca++ increase causes the acrosome vesicle (green) to fuse with the plasma membrane of the sperm and the vesicle undergoes exocytosis. | | | The increase in pHi causes the actin (pink) to go from the globular state to the filamentous state pushing out the acrosomal process and exposing | | | This causes an influx of Ca++ into the sperm head and an increase in pHi. |
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http://www.luc.edu/depts/biology/dev/acrosanm.htm
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| | Marie-France Pfenninger, Ph.D. |
| | The laboratory has determined the composition of some of these complexes and is in the process of studying their role in the biogenesis of the acrosome. | | | The acrosome is a cap-like vesicular organelle located in the anterior two-thirds of the sperm head. | | | We also have studied the maturation of the acrosome during sperm passage through the epididymis. |
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http://www.uchsc.edu/bsp/profiles/pfenningerm.htm
(290 words)
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| | Sperm receptor |
| | This is what is commonly referred to as the acrosome reaction. | | | Further research is required to identify the role of the ZP1 in the fertilization process as well as to explain the unexpected ZP2 binding results reported by Bleil and Wassarman in 1986. | | | The researchers proposed that ZP2 may act as a secondary receptor, interacting with the inner acrosomal membrane after the binding and release of ZP3. |
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http://www.ucalgary.ca/~browder/zonafunction.html
(994 words)
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| | Acrosome Reaction |
| | The acrosome reaction is a change in the sperm that is common to many higher animals. | | | The acrosomal vesicle (green) fuses with the plasma membrane, releasing enzymes from the tip of the sperm that aid digestion of egg jelly. | | | In response to signals presumably transduced by receptors on the surface of the sperm that bind to components of egg jelly (red), actin polymerizes from a pool of globular actin (pink) to form the acrosomal process. |
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http://worms.zoology.wisc.edu/urchins/SUfert_acrosome.html
(125 words)
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| | Gp273, the Ligand Molecule for Sperm-Egg Interaction in the Bivalve Mollusk, Unio elongatulus, Binds to and Induces ... |
| | Gp273, the Ligand Molecule for Sperm-Egg Interaction in the Bivalve Mollusk, Unio elongatulus, Binds to and Induces Acrosome Reaction in Human Spermatozoa Through a Protein Kinase C-Dependent Pathway | | | Gp273, the Ligand Molecule for Sperm-Egg Interaction in the Bivalve Mollusk, Unio elongatulus, Binds to and Induces Acrosome Reaction in Human Spermatozoa Through a Protein Kinase C-Dependent Pathway -- Delle Monache et al. | | | region, and that gp273 induces the acrosome reaction in human |
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http://www.biolreprod.org/cgi/content/abstract/69/6/1779
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| | SUE - Acrosome Reaction |
| | This induces the acrosome reaction causing the acrosome in green to fuse with the plasma membrane of the sperm. | | | The actin in pink goes from a globular state to a filamentous state pushing the front of the sperm outward exposing the binding receptors, blue. | | | The red receptors on the sperm come into contact with the egg jelly, yellow. |
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http://www.stanford.edu/group/Urchin/acrosome.htm
(87 words)
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| | things to come records - The New Direction - Home Page |
| | Photos from Horrorist & Acrosome live in Balingen, Germany. | | | Photos from Horrorist & Satronica live in Aalen, Germany. | | | Check out the new sticker designs and important re-ordering information. |
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http://www.thingstocome.com
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| | Acrosome |
| | In sperm cells of many higher animals, the acrosome develops over the anterior half of its head. | | | It is a cap-like structure derived from the Golgi apparatus. | | | The acrosome contains digestive enzymes (including hyaluronidase and acrosin) needed to penetrate the zona pellucida covering the ovum. |
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http://www.worldhistory.com/wiki/A/Acrosome.htm
(134 words)
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| | SUE - Acrosome Reaction |
| | The cytoplasm of the sperm contains NOS (Nitric Oxide Synthase) which is activated along with the acrosome reaction by contact with egg jelly [yellow] [NOS turns green here when activated]. | | | Activated NOS produces Nitric Oxide [light green spray]. | | | Macintosh: Hold click on animation and choose save to file |
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http://www.stanford.edu/group/Urchin/nos.htm
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