Acromegaly - Medicow
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Topic: Acromegaly



  
 Acromegaly
The pathogenesis of acromegaly: clinical and immunocytochemical analysis in 75 patients.
Acromegaly is usually treated by transsphenoidal surgery; a procedure in which all or part of a pituitary tumor is removed.
Because results are delayed, radiation therapy is rarely used to treat acromegaly without combining it with surgery or drug therapy.
http://hw.healthdialog.com/kbase/nord/nord51.htm   (2575 words)

  
 Acromegaly and Gigantism Summary - Acromegaly and Gigantism Information
Typically, the first step in treating acromegaly is surgical removal of a pituitary adenoma.
People with acromegaly have more skin tags, or outgrowths on the skin, than normal.
Under normal conditions, the pituitary's activity is directed by the hypothalamus, a small structure located at the base of the brain.
http://www.bookrags.com/other/health/acromegaly-and-gigantism-woh.html   (760 words)

  
 Acromegaly & Octreotide - Neuroendocrine Clinical Center & Pituitary Tumor Center at MGH/Harvard
Most patients note a marked improvement in their symptoms of acromegaly including headaches, joint pains and diaphoresis very soon after starting octreotide therapy.
Surgical cure is dependent on surgical skill and experience as well as the size of the tumor.
Jackson IMD, Barnard LB, Lamberton P. Role of a long-acting somatostatin analogue (SMS 201-995) in the treatment of acromegaly.
http://pituitary.mgh.harvard.edu/e-f-943.htm   (1260 words)

  
 UpToDate Patient information: Acromegaly (somatotroph adenomas)
Not all patients with acromegaly are alike, and it is important that your situation is individually evaluated by someone who knows you as a whole person.
Although no direct comparisons of pegvisomant have yet been reported, anecdotally it appears to be effective in lowering the serum IGF-1 concentration to normal even in many patients in whom surgery, radiation, and other medications were not successful.
Information provided by the National Institutes of Health, national medical societies, and some other well-established organizations are often reliable sources of information, although the frequency with which their information is updated is variable.
http://patients.uptodate.com/topic.asp?file=endo_hor/4528&title=Acromegaly   (2834 words)

  
 eMedicine - Acromegaly : Article by Robert A Schwartz, MD, MPH
A report of a case secondary to acromegaly treated with plastic surgery and x-ray therapy.
Deep barrel chest often is pronounced in long-standing acromegaly as a result of continued costal growth.
Ferguson et al showed that the mean skin thickness of 22 patients with acromegaly was increased many fold compared to 55 control subjects matched by age.
http://www.emedicine.com/derm/topic593.htm   (5717 words)

  
 SOMAVERT® and Acromegaly
SOMAVERT is indicated for the treatment of acromegaly in patients who have had an inadequate response to surgery and/or radiation therapy and/or other medical therapies, or for whom these therapies are not appropriate.
SOMAVERT is a medicine used to treat patients who have acromegaly.
Find product and condition information, downloads, and support.
http://www.acromegaly.com   (352 words)

  
 OHSU Pituitary Unit - Acromegaly
By contrast, IGF-1 is produced in the liver in response to GH stimulation and its value correlates with the average level of GH in the serum.
Acromegaly is particularly characterized by skeletal changes including enlarging hands and feet.
Growth hormone antagonist (GHA) therapy is a new treatment option and may soon become the most widely used medical adjunct treatment for acromegaly.
http://www.ohsupituitary.com/patients/acromeg.asp   (1251 words)

  
 Acromegaly and Acromegaly Symptoms and Sandostatin
Fortunately, there are several ways to successfully control acromegaly — including transsphenoidal surgery, medical therapy, and radiation therapy (radiotherapy).
Besides changes in appearance, acromegaly produces changes in the way the body works that can have serious health implications, which may include:
However, surgery is not right for everyone with acromegaly; for these patients, alternate treatments, such as medical therapy, are available.
http://www.us.sandostatin.com/info/pages/acromegaly/home.do   (924 words)

  
 Acromegaly - Wikipedia, the free encyclopedia
Currently, treatment options include surgical removal of the tumor, drug therapy, and radiation therapy of the pituitary.
The second medication used to treat acromegaly is octreotide (Sandostatin) and lanreotide (Somatulin).
Most patients with acromegaly respond to this medication.
http://en.wikipedia.org/wiki/Acromegaly   (1630 words)

  
 Filter Paper Collection of Plasma for IGF-I Test in Patients with Acromegaly -- Wu et al. 32 (3): 287 -- Annals of ...
to 88 ng/ml in 3 patients with surgically cured acromegaly.
to 503 ng/ml in 4 patients with recurrent acromegaly, and 27
11 patients with newly diagnosed but untreated acromegaly, 138
http://www.annclinlabsci.org/cgi/content/abstract/32/3/287   (349 words)

  
 The Pituitary Foundation Disorders Acromegaly
Acromegaly is a very rare condition and usually develops between the ages of 30 and 50.
The use of Somatostatin Analogues in Patients with Acromegaly.
If the condition develops before a person has stopped growing (which usually occurs between the ages of 15 to 17 years of age), it causes gigantism because growth hormone promotes growth of bones in the body.
http://www.pituitary.org.uk/disorders/acromegaly.htm   (264 words)

  
 Transgenic rabbits overexpressing growth hormone develop acromegaly and diabetes mellitus -- Costa et al. 12 (14): 1455 ...
Mastaglia, F. (1973) Pathological changes in skeletal muscle in acromegaly.
correlate better with clinically active acromegaly than the
phenotype that is not observed in acromegaly (14–16).
http://www.fasebj.org/cgi/content/full/12/14/1455   (3122 words)

  
 Acromegaly & Gigantism - Endocrinology - Medstudents
FROHMAN, Lawrence A.: "Clinical Review 22 Therapeutic Options in Acromegaly".
"Consensus Statement: Benefits Versus Risks of Medical Therapy for Acromegaly".
More than 10 ng/mL is found in 90% of patients with acromegaly.
http://www.medstudents.com.br/endoc/endoc8.htm   (1873 words)

  
 acromegaly on Encyclopedia.com
FDA approves first in a new class of medicines to treat acromegaly.
New study offers hope for patients with acromegaly, a rare, life-threatening hormonal disorder...; Treatment with Sandostatin LAR may reverse effects of acromegalic cardiomyopathy in young patients.
Acromegaly is usually caused by a tumor of the pituitary; treatment consists of irradiation or surgical removal of the tumor.
http://www.encyclopedia.com/html/a1/acromega.asp   (375 words)

  
 Tall Persons Club GB & Ireland · Medical Information · Acromegaly/Gigantism
Acromegaly: when normal growth is complete the ends of the long bones fuse, and the person has reached their final height.
The affected person will continue to grow upwards, as well as outwards, until secretion is stopped, by medical or surgical intervention.
If the pituitary starts to produce growth hormone again, the person will experience some upwards growth but, due to the fusion of the long bones, many bones, such as the lower jaw, will grow outwards.
http://www.tallclub.co.uk/medical/acromegaly.asp   (377 words)

  
 Novartis Pharmaceutical- A through Z - Acromegaly
Diseases and Conditions / A through Z / Acromegaly
Our aim is to get people's high blood pressure into the BP Success Zone (less than 140/90 to 120/80 mm HG or below).
Other changes in appearance, as well as inside the body, can also happen.
http://www.pharma.us.novartis.com/conditions/az/acromegaly.jsp   (131 words)

  
 Acromegaly
Because acromegaly is so uncommon and the physical changes occur so gradually, doctors often don't recognize it immediately.
Acromegaly usually develops slowly, and even your family members may not initially notice the gradual physical changes that occur with the disorder.
Progression of acromegaly can result in major health problems.
http://www.cnn.com/HEALTH/library/DS/00478.html   (1312 words)

  
 Acromegaly definition - Medical Dictionary definitions of popular medical terms
The cardinal manifestations of acromegaly include thickening of the skin, soft tissues, and bones of the hands and feet.
Inadequate treatment of pituitary gigantism or acromegaly is associated with increases in deaths from cardiovascular causes, cancer, and other causes.
Acromegaly definition - Medical Dictionary definitions of popular medical terms
http://www.medterms.com/script/main/art.asp?articlekey=2127   (355 words)

  
 Cardiovascular Function in Acromegaly -- Clayton 24 (3): 272 -- Endocrine Reviews
change in acromegaly is more likely secondary to the increased
Even with modern treatment, acromegaly is associated with a
Lie JT 1980 Pathology of the heart in acromegaly; anatomic findings in 27 autopsied patients.
http://edrv.endojournals.org/cgi/content/full/24/3/272   (4378 words)

  
 MedlinePlus Medical Encyclopedia: Acromegaly
Calling your health care provider Return to top
Call your health care provider if symptoms of acromegaly are present or if symptoms do not improve with treatment.
These medications may be used as initial treatment if surgery is unavailable or if the person is unable to tolerate surgery.
http://www.nlm.nih.gov/medlineplus/ency/article/000321.htm   (652 words)

  
 Long-term maintenance of the anabolic effects of GH on the skeleton in successfully treated patients with acromegaly -- ...
Conclusion: Our data suggest that the anabolic effect of GH on trabecular and cortical bone remains demonstrable after remission
clinical and biochemical cure of acromegaly remains to be established.
Long-term maintenance of the anabolic effects of GH on the skeleton in successfully treated patients with acromegaly -- Biermasz et al.
http://www.eje-online.org/cgi/content/abstract/152/1/53   (415 words)

  
 History of Acromegaly and Gigantism
Disclaimer: Please note that these web pages are an historical record and appreciation of acromegaly and gigantism and in no way represents current clinical guidelines or state of clinical practice.
Acromegaly and gigantism: An historical portrait of a disease
Recent updates include the addition of pages and information about postcards of giants and the modern equivalent in how the public tends to view giants from the popular press.
http://www.cladonia.co.uk/acromegaly   (129 words)

  
 Acromegaly
Post a question or comment on our Message Board
Find the clinical definition of acromegaly and treatment options.
A review of Acromegaly and Gigantism with focus on etiology, pathogenesis and treatment.
http://www.health-nexus.com/acromegaly.htm   (268 words)

  
 Endocrine System Diseases
Acromegaly: A New Therapy [KE Friend] - Cancer Control J/May-Jun 2002, HL Moffit Cancer Cenetr (US)
Patient's Guide to Acromegaly Diagnosis and Therapy [DM Cook] - The Pituitary Society (US)
Medical Guidelines for Diagnosis and Treatment of Acromegaly - AACE
http://micf.mic.ki.se/Diseases/C19.html   (2368 words)

  
 Veterinary Information - Hormonal Disorders of Cats
I have an 8 month old kitten who is very large framed, well muscled and
Acromegaly is a disorder in which there is overproduction of growth
I would like to know more about acromegaly in cats and how common it is.
http://www.vetinfo.com/cathorm.html   (753 words)

  
 Acromegaly
The symptoms of acromegaly may resemble other conditions or medical problems.
The disease also increases a patient's risk for cardiovascular disease and colon polyps that may lead to cancer.
Symptoms of acromegaly vary depending on how long the patient has had the disease.
http://www.healthsystem.virginia.edu/uvahealth/adult_endocrin/acromegaly.cfm   (318 words)

  
 Introduction: Acromegaly - WrongDiagnosis.com
Treatments for Acromegaly: Various information is available about treatments available for Acromegaly, or research treatments for other diseases.
Researching symptoms of Acromegaly: Further information about the symptoms of Acromegaly is available including a list of symptoms of Acromegaly, other diseases that might have similar symptoms in differential diagnosis of Acromegaly, or alternatively return to research other symptoms in the symptom center.
Misdiagnosis and Acromegaly: Research more detailed information about misdiagnosis of Acromegaly, underlying causes of Acromegaly (possibly misdiagnosed), or research misdiagnosis of other diseases.
http://www.wrongdiagnosis.com/a/acromegaly/intro.htm   (225 words)

  
 Modern treatment of acromegaly -- Merza 79 (930): 189 -- Postgraduate Medical Journal
Acromegaly is an endocrine disorder characterised by increased
Modern treatment of acromegaly -- Merza 79 (930): 189 -- Postgraduate Medical Journal
It is usually caused by a growth hormone
http://pmj.bmjjournals.com/cgi/content/abstract/79/930/189   (104 words)

  
 Sandostatin® LAR® approved in Japan for acromegaly and symptoms of gastrointestinal hormone secreting tumors
Sandostatin LAR is indicated for long-term maintenance therapy in acromegalic patients for whom medical therapy is appropriate and who have been shown to respond to and can tolerate Sandostatin® (octreotide acetate) injection.
In clinical studies of acromegaly, some patients experienced diarrhea, abdominal pain, flatulence, constipation, nausea, vomiting, pain at injection site, slow or irregular heart rate, and high or low blood sugar levels.
In studies of carcinoid syndrome, some patients experienced nausea, abdominal pain, headache, dizziness, fatigue, flatulence, vomiting, pain at injection site, and low blood sugar levels.
http://www.medicalnewstoday.com/index.php?newsid=7593   (663 words)

  
 Neuroendocrine Clinical Center & Pituitary Tumor Center at MGH/Harvard
Information on acromegaly, Cushing's disease or syndrome, prolactinoma, chromophobe or nonfunctioning pituitary adenoma, and thyrotroph adenomas
Including the Neuroendocrine Center Bulletin; A newsletter with information regarding pituitary tumors.
http://pituitary.mgh.harvard.edu   (677 words)

  
 Acromegaly -- eCureMe.com
In adults it is involved in regulatory functions in the body, but since the growth plates are closed, excessive levels cause abnormal growth of hands, feet, and internal organs.
Acromegaly is the excessive production of growth hormone, which continues to be produced well into adulthood.
http://www.ecureme.com/emyhealth/data/Acromegaly.asp   (152 words)

  
 acromegaly - OneLook Dictionary Search
acromegaly : The On-line Medical Dictionary [home, info]
acromegaly : Dorland's Illustrated Medical Dictionary [home, info]
acromegaly : Webster's Revised Unabridged, 1913 Edition [home, info]
http://www.onelook.com/?w=acromegaly&ls=a   (259 words)

  
 Sandostatin.com Global for Healthcare Professionals - Sandostatin LAR Home
Acromegaly is a rare and complex disease caused by overproduction of growth hormone.
http://www.sandostatin.com/index.html   (171 words)

  
 [No title]
Diseases : Endocrine Disorders : Pituitary : Acromegaly : HealthCentral - General Encyclopedia - Acromegaly
When excessive secretion of growth hormone occurs in children before normal growth has been completed, it causes gigantism rather than acromegaly.
Disease Directory : HealthCentral - General Encyclopedia - Acromegaly
http://www.diseasedirectory.net/detailed/22099.aspx   (45 words)

  
 Acromegaly
Acromegaly - Hands - Normal female hand for comparison.
For more information see the Online Mendelian Inheritance in Man (OMIM).
http://tray.dermatology.uiowa.edu/Acromeg.htm   (44 words)

  
 Reduction of Lung Distensibility in Acromegaly after Suppression of Growth Hormone Hypersecretion -- ...
Reduction of Lung Distensibility in Acromegaly after Suppression of Growth Hormone Hypersecretion -- GARCÍA-RÍO et al.
http://ajrccm.atsjournals.org/cgi/reprint/164/5/852   (28 words)

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