Colon carcinoma<

Colon carcinoma< - Medicow

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Topic: Colon carcinoma<

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MedlinePlus Medical Encyclopedia: <bb>>Colonb>bb>> cancer

When cancer arises from the lining of an organ like the large intestine, it is called a carcinoma.
Some evidence suggests that non-steroidal anti-inflammatory drugs (NSAIDs) may help prevent <bb>>colonb>bb>> cancer, but again, screening is still necessary.
Factors that increase the risk of <bb>>colonb>bb>> cancer are colorectal polyps, cancer elsewhere in the body, a family history of <bb>>colonb>bb>> cancer, and ulcerative colitis.

http://www.nlm.nih.gov/medlineplus/ency/article/000262.htm (1623 words)



eMedicine - Obstruction, Large Bowel : Article by Charles McCabe, MD

Sigmoid <bb>>colonb>bb>> and rectal tumors cause colonic obstruction much earlier in their development because the <bb>>colonb>bb>> is narrower and the stool is harder in that area.
Pathophysiology: Colonic obstruction that occurs from the rotating or twisting of the cecum or sigmoid <bb>>colonb>bb>> normally causes abrupt onset of symptoms.
Patient may describe intermittent, crampy abdominal pain that is colicky and relieved by assuming fetal position.

http://www.emedicine.com/emerg/topic65.htm (1623 words)



<bb>>Colonb>bb>> cancer

Eligible patients should be considered for entry into carefully controlled clinical trials comparing various postoperative chemotherapy regimens, postoperative radiation therapy, or biological therapy, alone or in combination.[ 4, 16 ] Refer to PDQ and to CancerNet ( http://cancernet.nci.nih.gov) for information on clinical trials for patients with stage III <bb>>colonb>bb>> cancer.
Beart RW, Moertel CG, Wieand HS, et al.: Adjuvant therapy for resectable colorectal carcinoma with fluorouracil administered by portal vein infusion: a study of the Mayo Clinic and the North Central Cancer Treatment Group.
For locally advanced disease, the role of radiation therapy with chemotherapy in <bb>>colonb>bb>> cancer is under clinical evaluation.

http://www.meds.com/pdq/colon_pro.html (1623 words)



MedlinePlus Medical Encyclopedia: <bb>>Colonb>bb>> cancer

Some evidence suggests that non-steroidal anti-inflammatory drugs (NSAIDs) may help prevent <bb>>colonb>bb>> cancer, but again, screening is still necessary.
Factors that increase the risk of <bb>>colonb>bb>> cancer are colorectal polyps, cancer elsewhere in the body, a family history of <bb>>colonb>bb>> cancer, and ulcerative colitis.
<bb>>Colonb>bb>> cancer is, in almost all cases, a treatable disease if caught early.

http://www.nlm.nih.gov/medlineplus/ency/article/000262.htm (1623 words)



Carcinoma in Situ of the Penis in a 76-Year-Old Circumcised Man

Significant past medical history included nonrecurrent bladder carcinoma, left hemicolectomy in 1964 for <bb>>colonb>bb>> adenocarcinoma, excision of a rectal tubovillous adenoma in 1994, benign prostatic hypertrophy status post-transuretharl resection of prostate, prostatourethritis in 1965, and hepatitis A with jaundice in 1942.
In one study of 11 men with carcinoma in situ of the penis, 10 had been circumcised as infants.
In a Danish study, men with localized squamous cell carcinoma of the penis were 7.81 times as likely to have been circumcised after the newborn period as the general population.

http://www.cirp.org/library/disease/cancer/vanhowe (1914 words)



Pooled Analysis of Fluorouracil-Based Adjuvant Therapy for Stage II and III <bb>>Colonb>bb>> Cancer: Who Benefits and by How Much? -- Gill et al. 22 (10): 1797 -- Journal of Clinical Oncology

Iwashyna TJ, Lamont EB: Effectiveness of adjuvant fluorouracil in clinical practice: A population-based cohort study of elderly patients with stage III <bb>>colonb>bb>> cancer.
therapy for stage II and III <bb>>colonb>bb>> cancer in an accessible format.
<bb>>colonb>bb>> cancers are observed with the MSI-H phenotype.

http://www.jco.org/cgi/content/full/22/10/1797 (1914 words)



Carcinoma in Situ of the Penis in a 76-Year-Old Circumcised Man

Significant past medical history included nonrecurrent bladder carcinoma, left hemicolectomy in 1964 for <bb>>colonb>bb>> adenocarcinoma, excision of a rectal tubovillous adenoma in 1994, benign prostatic hypertrophy status post-transuretharl resection of prostate, prostatourethritis in 1965, and hepatitis A with jaundice in 1942.
In one study of 11 men with carcinoma in situ of the penis, 10 had been circumcised as infants.
The detection of human papillomavirus deoxyribonucleic acid in intraepithelial, in situ verrucous and invasive carcinoma of the penis.

http://www.cirp.org/library/disease/cancer/vanhowe (1914 words)



Current Status of Sentinel Lymph Node Mapping and Biopsy: Facts and Controversies -- Jakub et al. 8 (1): 59 -- The Oncologist

Atypical ductal hyperplasia and ductal carcinoma in situ as revealed by large-core needle breast biopsy: results of surgical excision.
Ductal carcinoma in situ diagnosed with stereotactic core needle biopsy: can invasion be predicted?
Sentinel lymph node mapping for carcinoma of the <bb>>colonb>bb>>: a pilot study.

http://theoncologist.alphamedpress.org/cgi/content/full/8/1/59 (1914 words)



Strictures of the Sigmoid <bb>>Colonb>bb>>: Barium Enema Evaluation -- Blakeborough et al. 220 (2): 343 -- Radiology

Diverticulitis and carcinoma of the <bb>>colonb>bb>>: differential diagnosis.
oblique views of the sigmoid, supine oblique view of the cecum,
Sigmoid diverticular abscesses: percutaneous drainage as an adjunct to surgical resection in 24 cases.

http://radiology.rsnajnls.org/cgi/content/full/220/2/343 (1914 words)



Gastrointestinal II, Case 11

Adult <bb>>colonb>bb>> obstruction: carcinoma (65%), acute diverticulitis (20%), volvulus (5%), other-hernia, intussusception.
Colonic distention and the patient's history indicate a mechanical obstruction.
However, not infrequently with low (distal) colonic obstructions, the descending <bb>>colonb>bb>> is fluid filled accounting for its absence on the plain films.

http://www.indyrad.iupui.edu/rtf/teaching/medstudents/gastro2c2.htm (1914 words)



Colorectal Cancer Treatment, from Avastin.com

Avastin, used in combination with intravenous 5-fluorouracil-based chemotherapy, is indicated for first-line treatment of patients with metastatic carcinoma of the <bb>>colonb>bb>> or rectum.
In a small study, the incidence of serious or fatal hemoptysis was 31% in patients with squamous histology and 4% in patients with adenocarcinoma receiving AVASTIN as compared to no cases in patients treated with chemotherapy alone.
Serious, and in some cases fatal, hemoptysis has occurred in patients with non-small cell lung cancer treated with chemotherapy and AVASTIN.

http://www.avastin.com (245 words)



Liver Cancer Complete medical information associated with this form of cancer on MedicineNet.com

The subject of this article is hepatocellular carcinoma, which I will refer to as liver cancer.
When patients or physicians speak of liver cancer, however, they are often referring to cancer that has spread to the liver, having originated in other organs (such as the <bb>>colonb>bb>>, stomach, pancreas, breast, and lung).
Liver cancer (hepatocellular carcinoma) is a cancer arising from the liver.

http://www.medicinenet.com/liver_cancer/article.htm (2261 words)



The Political Graveyard: Politicians Who Died of <bb>>Colonb>bb>> Cancer

Died, of carcinoma of the sigmoid <bb>>colonb>bb>>, in North Adams,
Died, of <bb>>colonb>bb>> cancer, in South Woodstock, Woodstock,
Died, of <bb>>colonb>bb>> cancer, at George Washington University

http://politicalgraveyard.com/death/colon-cancer.html (2261 words)



Archives of Pathology & Laboratory Medicine: Focus of signet ring cell carcinoma in an adenoma of the sigmoid <bb>>colonb>bb>>

Hamazaki M, Kono S, Mimaya J, Ishihara A. Signet ring cell carcinoma in a polyp of the <bb>>colonb>bb>>: a case report of a six-year-old boy.
Histologic examination of the medium-sized polyp was consistent with an adenoma to carcinoma sequence for signet ring cell carcinoma of the <bb>>colonb>bb>>, similar to that for the common adenocarcinomas.
Signet ring cell carcinoma has been described in virtually all mucinous organs of the body, most frequently in the stomach,5 but also in the urinary bladder,6 prostate,7 pancreas,8 breast,9 lung,10 and elsewhere.

http://www.findarticles.com/p/articles/mi_qa3725/is_199910/ai_n8874375 (1121 words)



In Vitro and in Vivo Antitumor Activity of Methotrexate Conjugated to Human Serum Albumin in Human Cancer Cells -- Wosikowski et al. 9 (5): 1917 -- Clinical Cancer Research

Intratumoral Administration of Methotrexate Bound to Activated Carbon Particles: Antitumor Effectiveness against Human <bb>>Colonb>bb>> Carcinoma Xenografts and Acute Toxicity in Mice
PC3 (human prostate adenocarcinoma), T84 (human <bb>>colonb>bb>> carcinoma),
Colo-205 (human <bb>>colonb>bb>> carcinoma), WiDr (human <bb>>colonb>bb>> carcinoma),

http://clincancerres.aacrjournals.org/cgi/content/full/9/5/1917 (1121 words)



<bb>>Colonb>bb>> Carcinoma, EL SALVADOR ATLAS of Gastrointestinal VideoEndoscopy

It has been reported that carcinoma of the <bb>>colonb>bb>> occurring
Carcinoma of the transverse <bb>>colonb>bb>>, proximal to the
<bb>>Colonb>bb>> Carcinoma, EL SALVADOR ATLAS of Gastrointestinal VideoEndoscopy

http://www.gastrointestinalatlas.com/English/Colon_and_Rectum/Colon_Carcinoma/colon_carcinoma.html (1121 words)



Archives of the AFIP -- RadioGraphics 1995; 15: 127-146

Some adenocarcinomas of the <bb>>colonb>bb>>, however, develop not from preexisting adenomas but from a premalignant condition within flat mucosa called dysplasia.
This condition may be partially responsible for the carcinoma seen in patients with the hereditary nonpolyposis <bb>>colonb>bb>> cancer syndrome.
More common conditions associated with an increased risk of developing <bb>>colonb>bb>> carcinoma include a personal history of colorectal carcinoma or adenoma; a personal history of ovarian, endometrial, or breast cancer; and a history of <bb>>colonb>bb>> cancer or adenoma in a first-degree relative.

http://www.rsna.org/REG/publications/rg/afip/privateM/1995/0015/0001/0127/3.htm (1657 words)



Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human <bb>>colonb>bb>> carcinoma HT-29 cells

Together, these results identify molecular mechanisms of silibinin efficacy as a cell cycle regulator and apoptosis inducer in human <bb>>colonb>bb>> carcinoma HT-29 cells, and justify further studies to investigate potential usefulness of this nontoxic agent in <bb>>colonb>bb>> cancer prevention and intervention.
Silibinin upregulates the expression of cyclin-dependent kinase inhibitors and causes cell cycle arrest and apoptosis in human <bb>>colonb>bb>> carcinoma HT-29 cells
Silymarin, a defined mixture of natural flavonoid, has recently been shown to have potent cancer chemopreventive efficacy against <bb>>colonb>bb>> carcinogenesis in rat model; however, the mechanism of such efficacy is not elucidated.

http://www.nature.com/onc/journal/v22/n51/abs/1207158a.html (514 words)



Fluorouracil plus Levamisole as Effective Adjuvant Therapy after Resection of Stage III <bb>>Colonb>bb>> Carcinoma: A Final Report -- Moertel et al. 122 (5): 321 -- Annals of Internal Medicine

Surgical adjuvant therapy of large-bowel carcinoma: an evaluation of levamisole and the combination of levamisole and fluorouracil.
Effectiveness of Adjuvant Fluorouracil in Clinical Practice: A Population-Based Cohort Study of Elderly Patients With Stage III <bb>>Colonb>bb>> Cancer
Levamisole and fluorouracil for adjuvant therapy of resected <bb>>colonb>bb>> carcinoma.

http://www.annals.org/cgi/content/full/122/5/321 (4866 words)



Comparative Hepatology Abstract MHC class I expression protects rat <bb>>colonb>bb>> carcinoma cells from hepatic natural killer cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway

MHC class I expression protects CC531s <bb>>colonb>bb>> carcinoma cells from hepatic NK cell-mediated apoptosis and cytolysis, by blocking the perforin/granzyme pathway.
Therefore, using isolated rat hepatic NK cells and the syngeneic <bb>>colonb>bb>> carcinoma cell line CC531s, we investigated whether this protective role of MHC class I is also operative in hepatic NK cells, and addressed the mechanism of MHC class I protection.
Hepatic natural killer (NK) cells, the most cytotoxic cells of the natural occurring NK cells, are located in the liver sinusoids and are thus in a strategic position to kill arriving metastasising tumour cells, like <bb>>colonb>bb>> carcinoma cells.

http://www.comparative-hepatology.com/content/1/1/2/abstract (339 words)



Case of the Month July 2002

Transitional cell carcinoma of the right and left ovary with metastases to the omentum, serosa of the small intestine, serosa/adventitia and wall of rectosigmoid <bb>>colonb>bb>>, posterior pelvic peritoneum, posterior cervical region and lateral portions of uterus, and spleen.
On the other hand, some experts claim that transitional cell carcinoma of the ovary is a variant of serous carcinoma with pseudopapillary pattern, although the current view favors that transitional cell carcinoma of the ovary is a separate entity.
Immunohistochemical and pathological studies appear to favor that transitional cell carcinoma of ovary is one subtype of ovarian surface epithelial carcinomas, originating in celomic epithelium (as proposed by Austin and Norris 1987), and is different from urothelial carcinoma of urinary bladder.

http://www.hsc.wvu.edu/som/pathology/pathcases/apcases2003/apcasejan03/apcasejan03discussion.htm (339 words)



stage 3 <bb>>colonb>bb>> cancer

increase the overall survival in patients with TNM stage 3 <bb>>colonb>bb>> cancer, over those treated by surgery alone, from 46...
Stage 0 <bb>>colonb>bb>> cancer may be treated by cutting out the lesion, often via a colonoscopy...
Stage 0 <bb>>Colonb>bb>> Cancer (Carcinoma in Situ) Stage I <bb>>Colonb>bb>> Cancer.

http://www.youramazinglife.com/cancercures/11/stage-3-colon-cancer.html (339 words)



: The AMEDEO Literature Guide

Familial adenomatous polyposis associated with <bb>>colonb>bb>> carcinoma, desmoid tumour, gallbladder carcinoma, and endometrioid carcinoma: a case report.
MONAGHAN H, Williams AR Brenner tumour with carcinoma in situ: evidence for a spectrum from benign to malignant.
Alteration of PTEN expression in endometrial carcinoma is associated with down-regulation of cyclin-dependent kinase inhibitor, p27.

http://www.amedeo.com/medicine/ovc/histopa.htm (339 words)



: The AMEDEO Literature Guide

Familial adenomatous polyposis associated with <bb>>colonb>bb>> carcinoma, desmoid tumour, gallbladder carcinoma, and endometrioid carcinoma: a case report.
MONAGHAN H, Williams AR Brenner tumour with carcinoma in situ: evidence for a spectrum from benign to malignant.
Alteration of PTEN expression in endometrial carcinoma is associated with down-regulation of cyclin-dependent kinase inhibitor, p27.

http://www.amedeo.com/medicine/ovc/histopa.htm (339 words)



Melanoma immunotherapy by targeted IL-2 depends on CD4+ T-cell help mediated by CD40/CD40L interaction -- Lode et al. 105 (11): 1623 -- Journal of Clinical Investigation

Xiang, R., Lode, H.N., Gillies, S.D., and Reisfeld, R.A. T cell memory against <bb>>colonb>bb>> carcinoma is long lived in the absence of antigen.
Xiang, R., Lode, H.N., Dreier, T., Gillies, S.D., and Reisfeld, R.A. Induction of persistent tumor-protective immunity in mice cured of established <bb>>colonb>bb>> carcinoma metastases.
Suppression of human prostate carcinoma metastases in severe combined immunodeficient mice by interleukin 2 immunocytokine therapy.

http://www.jci.org/cgi/content/full/105/11/1623 (339 words)



T cell homeostatic proliferation elicits effective antitumor autoimmunity -- Dummer et al. 110 (2): 185 -- Journal of Clinical Investigation

Thirty-five days after challenge, splenocytes were cultured for 72 hours with either B78D14 melanoma cells (black bars) or MC-38 <bb>>colonb>bb>> carcinoma cells (white bars).
Ten days after challenge, splenocytes were coincubated with either irradiated B78D14 melanoma cells (filled squares) or irradiated MC-38 <bb>>colonb>bb>> carcinoma cells (open squares) for 48 hours; a standard 4-hour
The B6-derived B78D14 murine melanoma ( 17) and the MC-38 <bb>>colonb>bb>>

http://www.jci.org/cgi/content/full/110/2/185 (339 words)



Expression of histo-blood group A antigen increases resistance to apoptosis and facilitates escape from immune control of rat <bb>>colonb>bb>> carcinoma cells -- Marionneau et al. 12 (12): 851 -- Glycobiology

Expression of histo-blood group A antigen increases resistance to apoptosis and facilitates escape from immune control of rat <bb>>colonb>bb>> carcinoma cells -- Marionneau et al.
Expression of histo-blood group A antigen increases resistance to apoptosis and facilitates escape from immune control of rat <bb>>colonb>bb>> carcinoma cells
A and <bb>>Bb>bb>> histo-blood group antigens are present on carcinoma

http://glycob.oupjournals.org/cgi/content/abstract/12/12/851 (339 words)



MedlinePlus Medical Encyclopedia: <bb>>Colonb>bb>> cancer

Some evidence suggests that non-steroidal anti-inflammatory drugs (NSAIDs) may help prevent <bb>>colonb>bb>> cancer, but again, screening is still necessary.
Factors that increase the risk of <bb>>colonb>bb>> cancer are colorectal polyps, cancer elsewhere in the body, a family history of <bb>>colonb>bb>> cancer, and ulcerative colitis.
Diarrhea, constipation, or other change in bowel habits that does not resolve

http://www.nlm.nih.gov/medlineplus/ency/article/000262.htm (1623 words)



NordiQC

Among germ cell tumours, CEA is seen in most cases of embryonal carcinoma but rarely in the other types.
In normal adult tissue, CEA is expressed in the apical border and, to a lesser extent in the cytoplasm, of the columnar cells of <bb>>colonb>bb>> (Fig.
Among non-epithelial tumours, CEA may be detected in secretory meningioma (but not in other meningioma types) and in synovial and epitheloid sarcoma.

http://www.nordiqc.org/Epitopes/CEA/CEA.htm (1623 words)



carcinoma: Definition and Much More From Answers.com

Sometimes a tumour is referred to by the presumptive organ of the primary (eg carcinoma of the prostate) or the putative cell of origin (hepatocellular carcinoma, renal cell carcinoma).
The UICC/AJCC TNM system is often used, however for some common tumours, classic staging methods (such as the Dukes classification for <bb>>colonb>bb>> cancer) are still used.
Severely anaplastic tumours might be so undifferentiated that they do not have a distinct histological appearance.

http://www.answers.com/main/ntquery?method=4&dsid=2222&dekey=Carcinoma&gwp=8&curtab=2222_1&sbid=lc01a (1623 words)

Topic: <b>Colon</b> <b>carcinoma<

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